  Microfluidic mixing is a fundamental functionality in most lab on a chip (LOC) systems,whereas realization of efficient mixing is challenging in microfluidic channels due to the small Reynolds numbers. Here, we design and fabricate a compact three-dimensional (3D) micromixer to enable efficient mixing at various flow rates. The performance of the fabricated micromixer was examined using blue and red inks. The extreme flexibility in fabricating microfluidic structures of arbitrary 3D geometries using femtosecond laser micromachining allows us to tackle the major disadvantageous effects for optimizing the mixing efficiency. 
A compact and efficient three-dimensional microfluidic mixer