  To satisfy the ever-increasing capacity demand and quality of service (QoS) requirements of users, 5G cellular systems will take the form of heterogeneous networks (HetNets) that consist of macro cells and small cells. To build and operate such systems, mobile operators have given significant attention to cloud radio access networks (C-RANs) due to their beneficial features of performance optimization and cost effectiveness. Along with the architectural enhancement of C-RAN, large-scale antennas (a.k.a. massive MIMO) at cell sites contribute greatly to increased network capacity either with higher spectral efficiency or through permitting many users at once. In this article, we discuss the challenging issues of C-RAN based HetNets (H-CRAN), especially with respect to large-scale antenna operation. We provide an overview of existing C-RAN architectures in terms of large-scale antenna operation and promote a partially centralized approach. This approach reduces, remarkably, fronthaul overheads in CRANs with large-scale antennas. We also provide some insights into its potential and applicability in the fronthaul bandwidthlimited H-CRAN with large-scale antennas. 
Large-scale Antenna Operation in Heterogeneous Cloud Radio Access   Networks: A Partial Centralization Approach