  The problem of simulating the interaction of spacecraft travelling at velocities necessary for starflight with the interplanetary and interstellar medium is considered. Interaction of protons, atoms, and ions at kinetic energies relative to the spacecraft (MeV per nucleon) is essentially a problem of sputtering. More problematic is the impact of dust grains, macroscopic objects on the order of 10 nm ($10^{-21}$ kg) to 1 $\mu$m ($10^{-15}$ kg), the effects of which are difficult to calculate, and thus experiments are needed. The maximum velocity of dust grains that can be achieved at present in the laboratory using electrostatic methods is approximately 100 km/s, two orders of magnitude below starflight velocities. The attainment of greater velocities has been previously considered in connection with the concept of impact fusion and was concluded to be technologically very challenging. The reasons for this are explained in terms of field emission, which limits the charge-to-mass ratio on the macroscopic particle being accelerated as well as the voltage potential gradient of the accelerating electrostatic field, resulting in the accelerator needing to be hundreds to thousands of kilometers long for $\mu$m-sized grains. Use of circular accelerators (cyclotrons and synchrotrons) is not practical due to limitations on magnetic field strength making the accelerator thousands of kilometers in size for $\mu$m-sized grains. Electromagnetic launchers (railguns, coilguns) have not been able to produce velocities greater than conventional gas guns (< 10 km/s). The nearest feasible technologies (tandem accelerators, macromolecular accelerators) to reach the regime of projectile mass and velocity of interest are reviewed. Pulsed lasers are found to be the only facilities able to accelerate condensed phase matter to velocities approaching 1000 km/s but unlikely to be able to reach greater speeds. 
Experimental Simulation of Dust Impacts at Starflight Velocities