  We examine the dynamical evolution of the state of a neurone, with particular care to the non-equilibrium nature of the forces influencing its movement in state space. We combine non-equilibrium statistical mechanics and dynamical systems theory to characterise the nature of the neural resting state, and its relationship to firing. The stereotypical shape of the action potential arises from this model, as well as bursting dynamics, and the non-equilibrium phase transition from resting to spiking. Geometric properties of the system are discussed, such as the birth and shape of the neural limit cycle, which provide a complementary understanding of these dynamics. This provides a multiscale model of the neural cell, from molecules to spikes, and explains various phenomena in a unified manner. Some more general notions for damped oscillators, birth-death processes, and stationary non-equilibrium systems are included. 
Characterising the Non-Equilibrium Dynamics of a Neural Cell