hat
Alzayme a dwòg J147 (1146963-51-0), se yon potansyèl neuroprotective ak nerotwofik konpoze. J147 pwoteje kont neurotoxisite nan newòn kortik nan vitro (EC50 = 25 - 200 nM). J147. J147 ranvèse mantal defisyans nan sourit maladi alzayme a. J147 se yon konpoze nouvo enteresan ki trè pisan, san danje nan syans bèt ak oral aktif. J147 se yon potansyèl AD terapetik akòz kapasite li yo bay benefis imedya imedya, e li tou te gen potansyèl la sispann e petèt ranvèse pwogresyon maladi nan bèt sentòm jan yo demontre nan syans sa yo.
eng
Alzheimer’s drug J147(1146963-51-0), is a potent neuroprotective and neurotrophic compound. J147 protects against neurotoxicity in cortical neurons in vitro (EC50 = 25 – 200 nM). J147. J147 reverses cognitive impairment in aged Alzheimer’s disease mice. J147 is an exciting new compound that is extremely potent, safe in animal studies and orally active. J147 is a potential AD therapeutic due to its ability to provide immediate cognition benefits, and it also has the potential to halt and perhaps reverse disease progression in symptomatic animals as demonstrated in these studies.