hat
Finasterid se yon inibitè 5α-reduktaz, espesyalman tip II ak III isoenzymes yo. Pa anpeche 5α-reduktaz, finasteride anpeche konvèsyon nan testostewòn dihydrotestosteron (DHT) pa tip II a ak isoenzymes III, sa ki lakòz yon diminisyon nan nivo sòm DHT pa sou 65-70% ak nan nivo DHT pwostat yo pa jiska 85-90%, kote ekspresyon de isoenzyme kalite II a dominant.
eng
Finasteride is a 5α-reductase inhibitor, specifically the type II and III isoenzymes.By inhibiting 5α-reductase, finasteride prevents conversion of testosterone to dihydrotestosterone (DHT) by the type II and III isoenzymes, resulting in a decrease in serum DHT levels by about 65–70% and in prostate DHT levels by up to 85–90%,where expression of the type II isoenzyme predominates.