hat
Orlistat se yon pwisan entesten lipaz inhibiteur. Sa a dwòg se yon revèsib inhibite aktif-sit pou lipaz gastwoentestinal. Dwòg la fòme yon lyen kovalan ak sit la aktif serye nan pankreyas ak gastric lipasen, konsa anpeche aksyon yo ak anpeche grès nan rejim alimantè a nan men yo te idrolyzed ak absòbe. (NCI04).
eng
Orlistat is a powerful Intestinal Lipase Inhibitor. This drug is a reversible active-site inhibitor for gastrointestinal lipases. The drug forms a covalent bond with the active serine site in pancreatic and gastric lipases, thus inhibiting their action and preventing fat from the diet from being hydrolyzed and absorbed. (NCI04).