hat
Dirèk klorinasyon ak brominasyon ka kontinye byen kontrè ak nitrisyon ak sulfonation. 3-bromopyridin ka jwenn nan reyaksyon nan molekilè brom nan asid silfirik nan 130 ° C ak piridin. Lè yo fin fè klorinasyon, rezilta 3-Chloropyridine ka ba nan prezans klori aliminyòm ki aji kòm yon katalis nan 100 ° C. Dirèk reyaksyon nan alojene ak paladyòm (II) ka lakòz tou de 2-bromopyridine ak 2-Chloropyridine.
eng
Direct chlorination and bromination can continue well unlike nitration and sulfonation. 3-bromopyridine can be obtained through reaction of molecular bromine in sulphuric acid at 130 °C with pyridine. Upon chlorination, the result of 3-chloropyridine can be low in the presence of aluminum chloride which acts as a catalyst at 100 °C. Direct reaction of halogen and palladium (II) can result in both 2-bromopyridine and 2-chloropyridine.