hat
Sous prensipal la nan dopamine nan zòn sa a mitan-sèvo (striatum) se pwodwi nan zòn nan vegran tegmental (VTA). Li Lè sa a, ale nan nukleus accumbens (NAcc), sant lan rekonpans, an repons a je / Replik la / antisipasyon nan rekonpans la, chaje deklanche a pare pou aksyon. Aksyon an kap vini an - yon motè / aktivite mouvman, ki aktive pa yon siyal eksitateur 'ale jwenn li,' oswa yon siyal inhibition, tankou 'sispann', yo pral detèmine pa yon siyal soti nan cortical a prefrontal yon fwa li te trete enfòmasyon an. Dopamine an plis gen nan sant la rekonpans, se plis la estimilis a santi kòm yon rekonpans. Moun ki gen maladi konpòtman ki pa kontwole, oswa depandans, pwodwi twò fèb yon siyal soti nan cortical prefrontal la anpeche dezi a oswa aksyon san reflechi.
eng
The main source of dopamine in this mid-brain area (striatum) is produced in the ventral tegmental area (VTA). It then goes to the nucleus accumbens (NAcc), the reward centre, in response to the sight/cue/anticipation of the reward, loading the trigger ready for action. The next action – a motor/movement activity, activated by an excitatory signal ‘go get it,’ or an inhibiting signal, such as ‘stop’, will be determined by a signal from the prefrontal cortex once it has processed the information. The more dopamine there is in the reward centre, the more the stimulus is sensed as a reward. People with out-of-control behavioural disorders, or addictions, produce too weak a signal from the prefrontal cortex to inhibit the desire or impulsive action.