hat
Pati nan premye nan pwojè sa a pwal enplike retrospektiv imen analiz done MR yo devlope yon biomarqueur pou vasodilatory estati fonksyonèl nan rezo yo macro- ak mikwo-vaskilè patisipe nan ekipman pou san ak règleman pou ale ak pou ki nan sèvo imen an. Pati nan dezyèm pral kòmanse yon neroimajri bèt etid modèl konparatif, k ap aplike menm teknik yo MR D, ki lye ak l 'ak modèl la D aterosklereuz ap devlope nan Pwojè 2 ak fòmil yo nivo selilè nan fonksyon nerovaskulèr etidye nan Pwojè 1.
eng
The first part of this project will involve retrospective human MR data analysis to develop a biomarker for vasodilatory functional status of the macro- and micro-vascular networks involved in blood supply and regulation to and within the human brain. The second part will initiate a comparative animal neuroimaging model study, applying the same MR imaging techniques, linking it with the atherosclerotic imaging model being developed in Project 2 and the cellular level mechanisms of neurovascular function studied in Project 1.