hat
Inefikasite a se pwopòsyonèl dirèkteman avèk dòz dwòg la te pran. Kòm dòz la dwòg ogmante, pwodiksyon enèji vin pi rezèvwa, vitès metabolik ogmante (ak pi gwo kantite grès boule) pou satisfè demand enèji ak konpanse pou inefikasite la. DNP se youn nan ajan ki pi bon li te ye pou foslorylasyon oxidative uncoupling. Phosphorylation nan ADP pa ATP synthase vin "uncoupled oswa dekonekte soti nan oksidasyon.
eng
The inefficiency is directly proportional to the dose of the drug taken. As the drug dose increases, energy production becomes more inefficient, metabolic rate raises (and higher amount of fat is burned) to meet energy demands and compensate for the inefficiency. DNP is one of the best agent known for uncoupling oxidative phosphorylation. Phosphorylation of ADP by ATP synthase gets “uncoupled or disconnected from oxidation.