hat
Edaravone yo te montre yo atenere methamphetamine- ak 6-OHDA-induit dopaminergic neurotoxicity nan striatòm la ak sibstans nigra, epi yo pa afekte liberasyon dopamine methamphetamine-oswa hyperthermia. [5] [6] Li te tou yo te demontre pwoteje kont MPTP-medyat dopaminergic neurotoxicity nan sibstans lan nigra, menm si miyò pa striatòm la.
eng
Edaravone has been shown to attenuate methamphetamine- and 6-OHDA-induced dopaminergic neurotoxicity in the striatum and substantia nigra, and does not affect methamphetamine-induced dopamine release or hyperthermia.[5][6] It has also been demonstrated to protect against MPTP-mediated dopaminergic neurotoxicity to the substantia nigra, though notably not to the striatum.