hat
Yon repons iminitè vize pou MBP te fè nan enfeksyon maladi letal . Inokulasyon nan MBP jenere ogmante pèmeyabilite a nan baryè a san-sèvo (BBB), sa ki pèmèt iminite selil antre nan sèvo a, sit prensipal la nan raj viris replikasyon. Nan yon etid sou sourit ki enfekte avèk viris rabies Silver-chveu (SHBRV), pousantaj mòtalite nan sourit yo trete ak MBP amelyore 20% -30% sou gwoup la kontwòl trete. Li enpòtan pou note ke sourit ki pa enfekte yo te trete ak MBP te montre yon ogmantasyon nan to mòtalite ant 0% ak 40%.
eng
A targeted immune response to MBP has been researched in lethal rabies infection. The inoculation of MBP generates increases the permeability of the blood–brain barrier (BBB), allowing immune cells to enter the brain, the primary site of rabies virus replication. In a study of mice infected with Silver-haired bat rabies virus (SHBRV), the mortality rate of mice treated with MBP improved 20%-30% over the untreated control group. It is significant to note that healthy uninfected mice treated with MBP showed an increase in mortality rate between 0% and 40%.