I know someone who suffers from agoraphobia.
Really? What is agoraphobia? Is that one of the anxiety disorders?
It's the fear of wide open spaces. It can also be fear of crowds, which would cause social anxiety and even traveling short distances.
That sounds really difficult. Can it be treated with cognitive behavioral therapy?
Yes it can be treated with cognitive behavorial counseling.. I know it's considered an anxiety disorder.
I think agoraphobia doesn't usually resolve on its own, so therapy must be pretty important. 
Yes therapy is extremely important to help recovery. I was surprised to find out that it could also be inherited.
I did not know that.  Wow. I understand people who have this disorder are also at greater risk for substance abuse and depression. It sounds very hard.