I've heard so much about Grey's Anatomy, but I've never really watched any of it. What's it about?
Grey's Anatomy is a medical drama about protagonist Meredith Grey, she
Oh okay, so what makes this show different to other medical shows like House or something?
Well most shows like ER are about many doctors whereas Greys Anatomy is almost exclusively centered around Meredith and her work at the hospital as the Chief Surgeon.
Well what makes Meredith so special? Is she just a very talented surgeon?
She has an amazing head on her shoulders and her life is filled with drama. Love interests and all sorts of personal life terbulance. Season 2 was the best, it's mind blowing I watched it in 2005. 
Oh so it's not entirely about her occupation, but also her hectic life? That makes sense, drama really draws viewers in.
Yeah it's pretty clever the name of the show is a play on the "Gray's Anatomy" textbook commonly used in medical schools.