Have you ever watched South Park?  It's an animated adult sitcom on Comedy Central
I have. I think it has been on a long time?
It debuted in August 1997 and has had consistent high ratings.
Is it still on?
Actually it is!  It remains on of the highest rated shows and is slated to air new episodes through 2019
I think I need to watch it more!!
It's a lot like the Simpsons in that it uses a large ensemble cast of recurring characters.