Deadpool has genre Comedy
[Human]: Could you recommend a movie like Deadpool?  I'm looking for something funny! [Assistant]: Sure do you like Ryan Reynolds? [Human]: Yes, I like him a lot. [Assistant]: He stars in Harold and Kumar go to White Castle, that's a comedy!  [Human]: Oh, and an irreverent comedy, too. I love those!  Thanks for the suggestion! 
You're welcome! Some similar comedies are Zoolander and Zombieland as well if you'd like to check them out. 