how long at what temp do i cook meatloaf for?
<answer> A meatloaf should cooked at 350° for at least 60 minutes. <context> 13 Comments Latest Mar 29, 2016 by lagatta. 1  greygarious Jan 29, 2015 That's not an uncommon experience. Home cooks assume that published recipes have been tested and checked thoroughly but that is... 2  LindaWhit Jan 29, 2015 I've not made a 2+ lb. meatloaf in a long time, but when I do make them, they're usually at least 1 to 1-1/4 lbs. At 350°, I usually... I've not made a 2+ lb. meatloaf in a long time, but when I do make them, they're usually at least 1 to 1-1/4 lbs. At 350°, I usually bake at least 60 minutes. So for 2 lbs. of meat, I'd probably go at least 90 minutes. But definitely use a meat thermometer so you can properly gauge the internal temp.