what year did the spanish invade ecuador?
<answer> In 1532 the spanish invade ecuador. <context> 10 Facts About the Conquest of the Inca Empire. How Francisco Pizarro and 160 men defeated an Empire. History & Culture. In 1532, Spanish conquistadors under Francisco Pizarro first made contact with the mighty Inca Empire: it ruled parts of present-day Peru, Ecuador, Chile, Bolivia, and Colombia. Within 20 years, the Empire was in ruins and the Spanish were in undisputed possession of the Inca cities and wealth: Peru would continue to be one of Spain's most loyal and profitable colonies for another three hundred years. The conquest of the Inca looks unlikely on paper: 160 Spaniards against an Empire with millions of subjects.