6
Although this combination agent has been associated with a hypersensitivity syndrome involving cutaneous skin eruptions , pediatric cases of TMP - SMX - induced hepatotoxicity are rare .
 adverse effect: cutaneous skin eruptions, TMP - SMX; adverse effect: hepatotoxicity, TMP - SMX; adverse effect: hypersensitivity syndrome, TMP - SMX
Given a phrase that describes the relationship between two words, extract the words and the lexical relationship between them. The output format should be "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 adverse effect: cutaneous skin eruptions, TMP - SMX; adverse effect: hepatotoxicity, TMP - SMX; adverse effect: hypersensitivity syndrome, TMP - SMX