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We report a 50-year - old male patient with a 15-year history of psoriasis including mutilating psoriatic arthritis , in whom the withdrawal of cyclosporin A induced a generalised pustular exacerbation and a aggravation of the joint condition .
 adverse effect: aggravation of the joint condition, cyclosporin A; adverse effect: generalised pustular exacerbation, cyclosporin A
Given a phrase that describes the relationship between two words, extract the words and the lexical relationship between them. The output format should be "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 adverse effect: aggravation of the joint condition, cyclosporin A; adverse effect: generalised pustular exacerbation, cyclosporin A