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The chemotherapeutics , including vincristine , actinomycin D , and epirubicin in case 1 and vincristine and actinomycin D in case 2 , were given before the hepatotoxicity developed .
 adverse effect: hepatotoxicity, actinomycin D; adverse effect: hepatotoxicity, actinomycin D; adverse effect: hepatotoxicity, epirubicin; adverse effect: hepatotoxicity, vincristine; adverse effect: hepatotoxicity, vincristine
Given a phrase that describes the relationship between two words, extract the words and the lexical relationship between them. The output format should be "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 adverse effect: hepatotoxicity, actinomycin D; adverse effect: hepatotoxicity, actinomycin D; adverse effect: hepatotoxicity, epirubicin; adverse effect: hepatotoxicity, vincristine; adverse effect: hepatotoxicity, vincristine