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As these cases revealed , close monitoring of blood chemistry is mandatory after starting spironolactone , and patients should be advised to stop spironolactone immediately if diarrhoea develops .
 adverse effect: diarrhoea, spironolactone
Given a phrase that describes the relationship between two words, extract the words and the lexical relationship between them. The output format should be "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 adverse effect: diarrhoea, spironolactone