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PURPOSE : To investigate the concentration - side effect relationship in a patient with severe acyclovir - induced neurotoxicity and to summarize the information available in the literature about central nervous system side effects due to acyclovir .
 adverse effect: central nervous system side effects, acyclovir; adverse effect: neurotoxicity, acyclovir
Given a phrase that describes the relationship between two words, extract the words and the lexical relationship between them. The output format should be "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 adverse effect: central nervous system side effects, acyclovir; adverse effect: neurotoxicity, acyclovir