410
Several hypersensitivity reactions to cloxacillin have been reported , although IgE - mediated allergic reactions to the drug are rare and there is little information about possible tolerance to other semisynthetic penicillins or cephalosporins in patients with cloxacillin allergy .
 adverse effect: hypersensitivity, cloxacillin; adverse effect: IgE - mediated allergic reactions, cloxacillin
Given a phrase that describes the relationship between two words, extract the words and the lexical relationship between them. The output format should be "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 adverse effect: hypersensitivity, cloxacillin; adverse effect: IgE - mediated allergic reactions, cloxacillin