75
We further used immunohistochemistry ( IHC ) to examine the relative role of platelet - derived growth factor - B ( PDGF - B ) , insulin - like growth factor I ( IGF - I ) , transforming growth factor - beta1 ( TGF - beta1 ) and cyclooxygenase-2 ( COX-2 ) in the pathogenesis of BCNU - related pulmonary fibrosis .
 adverse effect: pulmonary fibrosis, BCNU
Given a phrase that describes the relationship between two words, extract the words and the lexical relationship between them. The output format should be "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 adverse effect: pulmonary fibrosis, BCNU