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The authors describe a case of valvular heart disease in a 48-year - old woman receiving benfluorex ( 150 mg t.i.d . for 8 years ) and leading to surgical mitral valve replacement .
 adverse effect: valvular heart disease, benfluorex
Given a phrase that describes the relationship between two words, extract the words and the lexical relationship between them. The output format should be "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 adverse effect: valvular heart disease, benfluorex