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Calcipotriol ( Daivonex R ; Leo Pharmaceuticals , Zurich , Switzerland ) may cause irritation of the skin , whereas allergic reactions are less common .
 adverse effect: allergic reactions, Calcipotriol; adverse effect: irritation of the skin, Calcipotriol
Given a phrase that describes the relationship between two words, extract the words and the lexical relationship between them. The output format should be "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 adverse effect: allergic reactions, Calcipotriol; adverse effect: irritation of the skin, Calcipotriol