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This case study is the second report of localized purpura after prolonged lamotrigine treatment suggesting this may be an atypical lamotrigine - induced drug reaction .
 adverse effect: localized purpura, lamotrigine
Given a phrase that describes the relationship between two words, extract the words and the lexical relationship between them. The output format should be "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 adverse effect: localized purpura, lamotrigine