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DISCUSSION : The main adverse effects of leflunomide consist of diarrhea , nausea , liver enzyme elevation , hypertension , alopecia , and allergic skin reactions .
 adverse effect: allergic skin reactions, leflunomide; adverse effect: alopecia, leflunomide; adverse effect: diarrhea, leflunomide; adverse effect: hypertension, leflunomide; adverse effect: liver enzyme elevation, leflunomide; adverse effect: nausea, leflunomide
Given a phrase that describes the relationship between two words, extract the words and the lexical relationship between them. The output format should be "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 adverse effect: allergic skin reactions, leflunomide; adverse effect: alopecia, leflunomide; adverse effect: diarrhea, leflunomide; adverse effect: hypertension, leflunomide; adverse effect: liver enzyme elevation, leflunomide; adverse effect: nausea, leflunomide