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We report 5 patients ( 3 patients with chronic hepatitis C treated with pegylated interferon alfa-2b in association with oral ribavirin and two patients with chronic myelocytic leukemia ) who developed local cutaneous reactions at sites of injection after the administration of weekly subcutaneous injections of pegylated interferon alfa-2b at different doses .
 adverse effect: local cutaneous reactions, pegylated interferon alfa-2b; adverse effect: local cutaneous reactions, pegylated interferon alfa-2b; adverse effect: local cutaneous reactions, ribavirin
Given a phrase that describes the relationship between two words, extract the words and the lexical relationship between them. The output format should be "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 adverse effect: local cutaneous reactions, pegylated interferon alfa-2b; adverse effect: local cutaneous reactions, pegylated interferon alfa-2b; adverse effect: local cutaneous reactions, ribavirin