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When pilsicainide is prescribed in patients with coronary artery disease or renal dysfunction , close attention must be paid to avoid life - threatening arrhythmias due to high plasma concentrations of the drug .
 adverse effect: life - threatening arrhythmias, pilsicainide
Given a phrase that describes the relationship between two words, extract the words and the lexical relationship between them. The output format should be "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 adverse effect: life - threatening arrhythmias, pilsicainide