11108
We now report the first known cancer patient who developed life - threatening complications after treatment with topical 5-FU and was shown subsequently to have profound DPD deficiency .
 adverse effect: life - threatening complications, 5-FU
Given a phrase that describes the relationship between two words, extract the words and the lexical relationship between them. The output format should be "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 adverse effect: life - threatening complications, 5-FU