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The intracellular domain of APP ( AICD ) has also emerged as a key epigenetic regulator of gene expression controlling a diverse range of genes , including APP itself , the amyloid - degrading enzyme neprilysin , and aquaporin - 1 .
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Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
 None