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Throughout the study ( 20 weeks ) , deaths related to cardiotoxicity were observed only in animals that received either free DOX or the mixture of HPMA copolymer and free DOX ; in these cases , histological investigations revealed marked changes in the heart that were consistent with DOX - induced cardiotoxicity .
 Disease: cardiotoxicity; Chemical: DOX; Chemical: HPMA; Chemical: DOX; Chemical: DOX; Disease: cardiotoxicity
Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Disease, Chemical 
Text: {0} 
Answer:
 Disease: cardiotoxicity; Chemical: DOX; Chemical: HPMA; Chemical: DOX; Chemical: DOX; Disease: cardiotoxicity