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We have previously shown that women with congenital isolated GH deficiency ( IGHD ) caused by a homozygous mutation in the GHRH receptor gene ( GHRHR ) ( MUT / MUT ) have a short reproductive life , with anticipated climacteric .
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Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
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