19964
However , modifications of both regions leads to more substantial decreases in agonist potency and efficacy to stimulate Gq - signaling , beta - arrestin recruitment , ERK1 / 2 phosphorylation and receptor internalization than to stimulate Gs .
 None
Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
 None