23657
Upon their discovery almost 40 years ago , isoforms of the lipid - activated protein kinase C ( PKC ) family were initially regarded only as downstream effectors of the second messengers calcium and diacylglycerol , undergoing activation upon phospholipid hydrolysis in response to acute stimuli .
 Chemical: calcium; Chemical: diacylglycerol
Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
 Chemical: calcium; Chemical: diacylglycerol