9460
CYP3A4 * 1B carriers and CYP3A5 expressers , independently or when assessed as a combined CYP3A4 - 3A5 genotype , had significantly lower dose - normalized pre - dose ( C ( 0 ) / dose ) and 2 - hour post - dose ( C ( 2 ) / dose ) concentrations of tacrolimus and metabolites .
 Chemical: tacrolimus
Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
 Chemical: tacrolimus