21998
In vivo equilibrium dissociation constant ( KD ) estimates for HAIs due to target binding by TMDD model with rapid binding approximation were 1 to 6 nM ( equivalent to 0 . 3 to 2 nM free drug ) , which appeared comparable to the in vitro Ki estimates ( 2 to 3 nM ) .
 None
Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
 None