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We developed a hybrid method for predicting plasma concentration - time curves in humans by integrating species differences in in vitro intrinsic clearance ( CL ( int ) ) into the Dedrick approach based on the allometry concept .
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Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
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