10261
The objectives of these studies were to explore the possibility of establishing of a link between the pharmacokinetics of TAK - 441 and the responses of Gli1 mRNA in tumor - associated stromal or skin cells and the antitumor effect of hedgehog inhibition .
 Chemical: TAK - 441
Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
 Chemical: TAK - 441