19542
Both in vivo and in vitro results demonstrate that leptin suppresses Isl - 1 expression and insulin secretion in islet in physiological and pathophysiological conditions , e . g . high fat diet .
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Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
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