1824
In accordance with the emerging repurposing trend of evaluating known compounds for novel pharmacological activity , ongoing research on augmentation of cholinergic signaling that has been aided by the use of opioids will be reviewed .
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Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
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