24400
Chemicals showing irreversible or slowly reversible binding to specific receptors will produce cumulative effects with time of exposure , and whenever the effects are also irreversible ( e . g . death ) they are reinforced over time ; these chemical have time - cumulative toxicity .
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Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
 None