2469
The isolation of crt5 - 262 , an additional cdc allele of POL1 / CDC17 , suggests for the first time that directly blocking DNA replication can provide a signal to induce the DNA damage response . crt2 mutants show a defect in basal level expression of RNR1 - lacZ reporter constructs .
 GENE: crt5 - 262; GENE: cdc allele; GENE: POL1; GENE: CDC17; GENE: crt2 mutants; GENE: RNR1; GENE: lacZ
Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: GENE 
Text: {0} 
Answer:
 GENE: crt5 - 262; GENE: cdc allele; GENE: POL1; GENE: CDC17; GENE: crt2 mutants; GENE: RNR1; GENE: lacZ