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Most missense mutations in AHI1 , causing JBTS , occur in known protein domains , however , a common V443D mutation in AHI1 is found in a region with no known protein motifs .
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Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
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