2004
Phenotypic and molecular analyses of patients with partial chromosome 21 monosomy enabled us to define a region , spanning 2 . 4 Mb between D21S190 and D21S226 , associated with arthrogryposis , mental retardation , hypertonia , and several facial anomalies .
 GENE: D21S190; GENE: D21S226
Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: GENE 
Text: {0} 
Answer:
 GENE: D21S190; GENE: D21S226