12412
These results indicate that the Warburg - like effect , which is characteristic of aerobic metabolism in cancer cells by which lactate is overproduced with reduced linking to mitochondria metabolism , plays an important role in impaired metabolism - secretion coupling in diabetic beta - cells and suggest that ROS reduction can improve mitochondrial metabolism by suppressinglactate overproduction through inhibition of HIF1 alpha stabilization .
 Chemical: lactate; Chemical: suppressinglactate
Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
 Chemical: lactate; Chemical: suppressinglactate