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Pretreatment with S . virgaurea extract for 5 weeks at a dose of 250 mg / kg followed by isoproterenol injection significantly prevented the observed alterations .
 Chemical: isoproterenol
Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Disease, Chemical 
Text: {0} 
Answer:
 Chemical: isoproterenol