1862
Here , we report unexpected rearrangements to the insulin / IGF - 1 pathway , whereby the insulin - like receptor DAF - 2 and 3 - phosphoinositide - dependent protein kinase PDK - 1 oppose AKT - 1 to promote DNA damage - induced apoptosis .
 Chemical: phosphoinositide
Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
 Chemical: phosphoinositide