5694
We describe the 3D - QSAR - assisted design of an Aurora kinase A inhibitor with improved physicochemical properties , in vitro activity , and in vivo pharmacokinetic profiles over those of the initial lead .
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Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
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