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The results of the transient - transfection assay showed that the Sp1 binding element located in the core region ( positions - - 64 to + 1 ) of the alpha2 - integrin promoter plays an essential role in the alpha2 - integrin promoter activity and its downregulation by Erb - B2 .
 GENE: Sp1 binding element; GENE: alpha2 - integrin promoter; GENE: alpha2 - integrin promoter; GENE: Erb; GENE: B2
Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: GENE 
Text: {0} 
Answer:
 GENE: Sp1 binding element; GENE: alpha2 - integrin promoter; GENE: alpha2 - integrin promoter; GENE: Erb; GENE: B2