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In a screen for markers of tumor angiogenesis , we recently identified high - mobility group box 1 ( HMGB1 ) , known to act as proinflammatory cytokine and chromatin - binding molecule .
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Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
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