8080
Tacrolimus , although effective against AD , is a challenging molecule due to low solubility , low - penetration , poor - bioavailability , and toxicity .
 Chemical: Tacrolimus
Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
 Chemical: Tacrolimus