1546
These observations suggest that clr4 + and rik1 + must play a role in the assembly of Swi6p into a transcriptionally silent , inaccessible chromatin structure at fission yeast centromeres which is required to facilitate interactions with spindle microtubules and to ensure normal chromosome segregation .
 GENE: clr4 +; GENE: rik1 +; GENE: Swi6p
Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: GENE 
Text: {0} 
Answer:
 GENE: clr4 +; GENE: rik1 +; GENE: Swi6p