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Molecular modeling coupled with site - directed mutagenesis suggests that ICA binds in a channel - specific orientation to a hydrophobic pocket bounded by the S5 / pore helix / S6 of one subunit and S6 of an adjacent subunit .
 Chemical: ICA
Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
 Chemical: ICA