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Objectives of the present study were as follows : 1 ) to characterize crizotinib time - dependent inhibition ( TDI ) potency for CYP3A in human liver microsomes ( HLM ) and cryopreserved human hepatocytes suspended in human plasma ( HSP ) ; 2 ) to characterize crizotinib enzyme induction potency on CYP3A4 in cryopreserved human hepatocytes ; 3 ) to predict crizotinib steady - state plasma concentrations in patients ( e . g . , autoinhibition and autoinduction ) using the mechanistic dynamic model , Simcyp population - based simulator ; and 4 ) to predict a clinical crizotinib - midazolam interaction using the dynamic model as well as the static mathematical model .
 Chemical: crizotinib; Chemical: crizotinib; Chemical: crizotinib; Chemical: crizotinib; Chemical: midazolam
Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
 Chemical: crizotinib; Chemical: crizotinib; Chemical: crizotinib; Chemical: crizotinib; Chemical: midazolam