9598
Interestingly , the substituents on the methylene bridge showed strong influences on the inhibitory activities leading to opposite effects , that is , a given substituent showed an increase in inhibition of one enzyme , while it led to a decrease for the other enzyme .
 Chemical: methylene
Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
 Chemical: methylene