3515
Isotretinoin is contraindicated in pregnancy because of the many reported congenital abnormalities after maternal use ( including microphthalmos , orbital hypertelorism , and optic nerve hypoplasia ) .
 Chemical: Isotretinoin; Disease: congenital abnormalities; Disease: microphthalmos; Disease: hypertelorism; Disease: optic nerve hypoplasia
Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Disease, Chemical 
Text: {0} 
Answer:
 Chemical: Isotretinoin; Disease: congenital abnormalities; Disease: microphthalmos; Disease: hypertelorism; Disease: optic nerve hypoplasia