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To investigate the effect of hyperthyroidism on the pattern and time course of O2 uptake ( VO2 ) following the transition from rest to exercise , six patients and six healthy subjects performed cycle exercise at an average work rate ( WR ) of 18 and 20 W respectively .
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Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: GENE 
Text: {0} 
Answer:
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