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Because vigorous growth of malignant tumors may create stressful conditions , such as hypoglycemia , hypoxia , or accumulation of misfolded proteins during revved up protein synthesis , the adaptive , pro - survival components of the ER stress response system ( e . g . , GRP78 / BiP ) are frequently found chronically activated in tumor cells .
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Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
 None