12326
These epigenetic changes were accompanied by the activation of members of the ERK pathway as well as increased expression of the immediate early genes ( IEG ) c - fos and activity - regulated cytoskeleton - associated protein ( Arc / Arg3 . 1 ) .
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Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
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