3259
Estrogen has positive effects on mood , sexual function , target end organs and cognitive function , and may play an important role in the etiology of Alzheimer ' s Disease by acting to prevent amyloid plaque formation , oxidative stress , or deterioration of the cholinergic neurotransmitter system .
 None
Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: GENE 
Text: {0} 
Answer:
 None