12432
The RNA levels for Sp - 1 and eNOS phosphorylation were decreased , while p65NF kappa B phosphorylation , cleaved PARP - 1 and COX - 2 expression were increased in arteries from diabetic mice , which were restored after NF kappa B inhibition and in db ( - ) / db ( - p50NF kappa B - / - ) and db ( - ) / db ( - PARP - 1 - / - ) mice . In the present study , we provided evidence that enhanced NF kappa B activity impairs vascular function by PARP - 1 , Sp - 1 and COX - 2 - dependent mechanisms in male type 2 diabetic mice .
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Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
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