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To the best of our knowledge , this is the first time that cyclo - ( His , Leu ) has been isolated from natural products .
 Chemical: cyclo - ( His , Leu )
Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
 Chemical: cyclo - ( His , Leu )