3045
In both cell types , insulin led to a dose - dependent increase in the association of tyrosine phosphorylated IRS - 1 with the SH2 domain of the p85 regulatory subunit of PI - 3 kinase , and also increased the amount of PI kinase activity detected in anti - IRS - 1 immunoprecipitates .
 GENE: insulin; GENE: tyrosine phosphorylated IRS - 1; GENE: SH2 domain; GENE: p85 regulatory subunit; GENE: PI - 3 kinase; GENE: PI kinase; GENE: anti - IRS - 1
Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: GENE 
Text: {0} 
Answer:
 GENE: insulin; GENE: tyrosine phosphorylated IRS - 1; GENE: SH2 domain; GENE: p85 regulatory subunit; GENE: PI - 3 kinase; GENE: PI kinase; GENE: anti - IRS - 1