3945
A significant up - regulation in the expression of apoptosis markers such as P ( 53 ) , P ( 21 ) and cleaved caspase - 3 was observed , while the levels were down - regulated for Bcl ( 2 ) at both mRNA and protein levels .
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Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
 None