4636
This report describes unique contrast enhancement of the white matter on T1 - weighted magnetic resonance images of two patients with disseminated necrotizing leukoencephalopathy , which developed from acute lymphoblastic leukemia treated with high - dose methotrexate .
 Disease: leukoencephalopathy; Disease: acute lymphoblastic leukemia; Chemical: methotrexate
Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Disease, Chemical 
Text: {0} 
Answer:
 Disease: leukoencephalopathy; Disease: acute lymphoblastic leukemia; Chemical: methotrexate