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The results demonstrated that intracerebral infusions of LTD4 ( 1 ng / mouse ) produced memory impairment as determined by Morris water maze test and Y - maze test in mice , and caused the accumulation of A beta 1 - 40 and A beta 1 - 42 in the hippocampus and cortex through increased activity of beta - and gamma - secretases accompanied with increased expression of amyloid precursor protein ( APP ) .
 Chemical: LTD4
Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
 Chemical: LTD4