9020
Further , E - 64d - pretreated seizure rats ( EXP2 ) showed a significant downregulation of mRNA expression of PRG - 1 , PRG - 3 and PRG - 5 , cathepsin B and ApoE , as well as up - regulated nSMase and ANX7 in hippocampus when compared with EXP1 rats .
 Chemical: E - 64d
Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
 Chemical: E - 64d