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Angiogenesis is controlled positively or negatively by extrinsic and intrinsic molecular cues in endothelial cells ( ECs ) ; in the tumor microenvironment , the action of positive regulators exceeds that of negative regulators .
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Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
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