15306
In these studies , nicotine ' s effects are predominately negative , inhibiting bone cell metabolism and fracture repair , whereas most in vitro studies reported biphasic responses in all bone cells except osteoclastic cells .
 Chemical: nicotine
Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
 Chemical: nicotine