21257
The results suggest that although the dual delivery of TGF - beta 3 and IGF - 1 may not synergistically enhance the quality of engineered tissue , the delivery of IGF - 1 alone from bilayered composite hydrogels positively affects osteochondral tissue repair and holds promise for osteochondral tissue engineering applications .
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Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
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