1614
CONCLUSIONS : These results suggest that bupivacaine stimulates COX - 2 gene expression after tissue injury , which is associated with higher PGE2 production and pain after the local anesthetic effect dissipates .
 Chemical: bupivacaine; Disease: tissue injury; Chemical: PGE2; Disease: pain
Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Disease, Chemical 
Text: {0} 
Answer:
 Chemical: bupivacaine; Disease: tissue injury; Chemical: PGE2; Disease: pain