20665
As seen in a recently reported structure of the related tyrosine kinase Syk , Tyr 315 of ZAP - 70 is part of a hydrophobic interface between the regulatory apparatus and the kinase domain , and the integrity of this interface would be lost upon engagement of doubly - phosphorylated peptides by the SH2 domains .
 Chemical: tyrosine; Chemical: Tyr
Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
 Chemical: tyrosine; Chemical: Tyr