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In the present study , the effect of chronic pre - treatment with metformin on cardiac dysfunction and toll - like receptor 4 ( TLR4 ) activities following myocardial infarction and their relation with AMPK were assessed .
 Chemical: metformin; Disease: cardiac dysfunction; Disease: myocardial infarction
Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Disease, Chemical 
Text: {0} 
Answer:
 Chemical: metformin; Disease: cardiac dysfunction; Disease: myocardial infarction