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An antisense oligonucleotide ( ASO ) was used to correct defective pre - mRNA splicing of transcripts from the USH1C gene with the c . 216G > A mutation , which causes human Usher syndrome , the leading genetic cause of combined deafness and blindness .
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Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
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