2850
Leptin signaling is required for normal bone homeostasis ; however , loss of leptin results in differing effects on cortical and cancellous bone , as well as altered responses between the axial and appendicular regions .
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Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
 None