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The recognition of the prognostic value of human papillomavirus ( HPV ) status , and the advent of biologically targeted therapies with potential for decreased toxicities and increased selectivity , represent significant developments in our understanding of SCCHN .
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Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
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