21127
Our present results suggest that CAR - mediated induction of these enzymes can not be understood by ligand binding alone because the specificity and magnitude of induction are co - determined by a given cell signaling such as p38 MAPK ; both physiological and pathophysiological states of cell signaling may have a strong impact in hepatic drug metabolizing capability during therapeutic treatments .
 None
Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
 None