1325
Bone insulin signaling is known to support bone metabolism ; therefore , we also tested the hypothesis that OVX DMII rats ( DOVX ) would exhibit greater reductions in the expression of proteins important in insulin signaling , including IRS - 1 , IRS - 2 , and IGF - 1 .
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Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
 None