4661
The occurrence of a profound alteration in NK receptor expression in RMDD is a novel finding that suggests NK - 1R and NK - 2R pathways as possible relevant players in major depressive disorder , so improving our understanding of the complex pathogenesis of the disease .
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Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
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