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To address the role of the isoform backbone on function , we generated a transgenic mouse in which the endogenous alpha - MHC was partially replaced with transgenically encoded beta - MHC or alpha - MHC .
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Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
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