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We examined transactivation activity of the PXR mutants in gene reporter assays , formation of PXRmutant / RXR alpha heterodimer , binding of PXR mutants to the CYP3A4 gene response element DR3 and CYP3A4 expression in HepG2 cells after expression of the mutants .
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Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
 None