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Our data suggest that the C to A mutation at the penultimate nucleotide of exon 6 of the CYP27 gene not only causes the deficiency in the sterol 27 - hydroxylase activity , but also partially leads to alternative pre - mRNA splicing of the gene .
 Disease: deficiency in the sterol 27 - hydroxylase activity
Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Disease 
Text: {0} 
Answer:
 Disease: deficiency in the sterol 27 - hydroxylase activity