1541
However , these animals had shown a significant increase in heart rate beginning at 8 weeks after drug administration ( P less than 0 . 01 ) . ( ABSTRACT TRUNCATED AT 400 WORDS )
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Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Disease, Chemical 
Text: {0} 
Answer:
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