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The reliability of current tests in predicting the onset , progression and response to various regimens for diabetic nephropathy is still under debate ; and it has engendered a search for more sensitive and specific urinary biomarkers , especially those reflective of tubular dysfunctions .
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Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
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