2820
These data also suggest the existence of a mechanism by which regulatory subunits modulate the PI 3 - kinase - mediated signals , independent of the kinase activity , possibly through subcellular localization of the catalytic subunit or interaction with additional signaling molecules .
 GENE: PI 3 - kinase
Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: GENE 
Text: {0} 
Answer:
 GENE: PI 3 - kinase