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However , although several studies have demonstrated the relationship between estrogen and glucose uptake via PI3K / Akt in other tissues , not too much is known about the possible cross talk between them for development and maintenance of breast cancer .
 Chemical: estrogen; Chemical: glucose
Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
 Chemical: estrogen; Chemical: glucose