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Together , these data identify the Ide gene as a regulator of GSIS , suggest a molecular mechanism for beta - cell degeneration as a consequence of Ide deficiency , and additionally corroborates and extends a previously established important role for alpha - synuclein in beta - cell function .
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Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
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