15305
In vivo studies of the effects of nicotine in animals demonstrated widespread effects on bone including osteoneogenesis , osseointegration , steady - state skeletal bone and genes and cytokines relevant to bone cell physiology and bone homeostasis .
 Chemical: nicotine
Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
 Chemical: nicotine