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The germline T - to - A transversion responsible for the APC I1307K allele converts the wild - type sequence to a homopolymer tract ( A8 ) that is genetically unstable and prone to somatic mutation .
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Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Disease 
Text: {0} 
Answer:
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