13443
In this review we highlight some recent studies that have identified structural elements within GluN2 subunits that contribute to the heterogeneous biophysical properties of NMDARs , consider why some recently described novel pharmacological tools may permit better identification of native NMDAR subtypes , examine the evidence that NMDAR subtypes differentially contribute to the induction of long - term potentiation and long - term depression and discuss how through the use of chimeric proteins additional insights have been obtained that account for NMDAR subtype - dependency of physiological and pathophysiological signalling .
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Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
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