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In this study , using the human colon cancer cell line HCT116 , we find that established HCT116 / IGF1 - R transfectants exhibit a more aggressive transformed phenotype than the parental cell line , as demonstrated by their higher proliferation rate in response to IGF1 , higher degree of anchorage - independent growth , resistance to serum deprivation - induced apoptosis , and higher migratory capability in a monolayer " wounding assay . " When injected into nude mice , HCT116 / IGF1 - R transfectants were highly invasive and produced distant metastases , whereas the parental cell did not .
 Anatomy: colon cancer cell line HCT116; Anatomy: HCT116 / IGF1 - R transfectants; Anatomy: parental cell line; Anatomy: serum; Anatomy: monolayer; Anatomy: HCT116 / IGF1 - R transfectants; Anatomy: metastases; Anatomy: parental cell
Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Anatomy 
Text: {0} 
Answer:
 Anatomy: colon cancer cell line HCT116; Anatomy: HCT116 / IGF1 - R transfectants; Anatomy: parental cell line; Anatomy: serum; Anatomy: monolayer; Anatomy: HCT116 / IGF1 - R transfectants; Anatomy: metastases; Anatomy: parental cell