581
Systemic or local administration of AMN082 into the nucleus accumbens ( NAc ) , a critical brain region involved in reward and drug dependence processes , inhibited the reinforcing and motivational effects of cocaine , heroin and ethanol , as assessed by the intravenous drug self - administration procedure .
 Chemical: AMN082; Chemical: cocaine; Chemical: heroin; Chemical: ethanol
Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
 Chemical: AMN082; Chemical: cocaine; Chemical: heroin; Chemical: ethanol