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Targeting the highly conserved kinase domain in these systems represents a promising strategy for the design of a broad - spectrum antibiotic ; however , development of such compounds has been marred by an incomplete understanding of the conserved binding features within the active site that could be exploited in molecule design .
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Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
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