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The discovery of constitutive activation of the BRAF kinase caused by activating BRAF ( V600E ) kinase mutation in most melanoma patients led to the discovery of the first potent BRAF ( V600E ) signaling inhibitor , vemurafenib .
 Chemical: vemurafenib
Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
 Chemical: vemurafenib