13239
Methotrexate , the standard disease - modifying anti - rheumatic drug ( DMARD ) , has shown a gradual loss of efficacy in a significant proportion of patients , probably due to the onset of drug resistance , and thus it was hoped that the development of biologics would revolutionise RA management .
 Chemical: Methotrexate
Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
 Chemical: Methotrexate