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Variability in the number of colorectal adenomas was most apparent in individuals with mutations in region 1 , and upper - gastrointestinal manifestations were more severe in them .
 Disease: colorectal adenomas
Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Disease 
Text: {0} 
Answer:
 Disease: colorectal adenomas