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While analyzing a large data set of a discovery study for diagnostic biomarkers of the Parkinson ' s Disease ( " ParkCHIP " ) we have revealed the need for distinct improvements of the suggested workflow concerning raw data acquisition , normalization and pre - selection method availability , batch effects , feature selection , and feature validation .
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Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
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