4704
The incidence of neurotoxicity may be reduced by employing lower doses of methotrexate in the presence of central nervous system leukemia , in older children and adults , and in the presence of epidural leakage .
 Disease: neurotoxicity; Chemical: methotrexate; Disease: central nervous system leukemia
Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Disease, Chemical 
Text: {0} 
Answer:
 Disease: neurotoxicity; Chemical: methotrexate; Disease: central nervous system leukemia