621
Kinetic studies of binding and dissociation revealed that various truncation mutants have 3 - 5 - fold higher affinity to various DNA - binding sites when compared with the wild - type PAX6 .
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Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Disease 
Text: {0} 
Answer:
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