4897
Site - directed mutagenesis of the conserved cysteine residue ( tom1C3235A ) in the hect - domain , supposed to be necessary for thioester - bond formation with ubiquitin , abolished the gene function .
 GENE: tom1C3235A; GENE: hect - domain; GENE: ubiquitin
Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: GENE 
Text: {0} 
Answer:
 GENE: tom1C3235A; GENE: hect - domain; GENE: ubiquitin