1031
While the binding of IL-2 to its receptor was recently shown to lead to the activation of two kinases , Jak-1 and Jak-3 , subsequent steps in the signaling pathway to the nucleus that lead to the activation of specific genes had not been characterized.
 protein: Jak-1; protein: IL-2; protein: Jak-3; protein: kinases
Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: cell line, protein, RNA, DNA, cell type 
Text: {0} 
Answer:
 protein: Jak-1; protein: IL-2; protein: Jak-3; protein: kinases