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Osteocyte - originated signals may also contribute to the increased bone fragility associated with bone matrix disorders like osteogenesis imperfecta , and perhaps the rapid reversal of bone turnover above baseline following discontinuation of anti - resorptive treatments , like denosumab .
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Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
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