15307
EXPERT OPINION : The review suggests that nicotine has effects on osteoneogenesis , osseointegration and steady - state skeletal bone in animal in vivo models , as well as effects on all ' bone cells ' , via several mechanisms in both animal and human cell in vitro studies .
 Chemical: nicotine
Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
 Chemical: nicotine