8128
Although estrogen involves in the adaptive responses of bone cells to mechanical loadings , its effects on osteocytic Cx43 - based gap junction intercellular communication ( GJIC ) remain obscure .
 Chemical: estrogen
Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
 Chemical: estrogen