25490
OBJECTIVEThis study assessed the ability to distinguish between type 1 diabetes - affected individuals and their unaffected relatives using HLA and single nucleotide polymorphism ( SNP ) genotypes . RESEARCH DESIGN AND METHODSEight models , ranging from only the high - risk DR3 / DR4 genotype to all significantly associated HLA genotypes and two SNPs mapping to the cytotoxic T - cell - associated antigen - 4 gene ( CTLA4 ) and insulin ( INS ) genes , were fitted to high - resolution class I and class II HLA genotyping data for patients from the Type 1 Diabetes Genetics Consortium collection .
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Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
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