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Here we demonstrate that under hypoxic conditions , the ubiquitin ligase Siah ( seven in absentia homolog ) 2 controls ASPP2 availability , with concomitant effect on epithelial cell polarity .
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Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
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