2335
It is increasingly observed that the majority of pharmaceutical drugs , even those believed to have minimal adverse effects , such as proton pump inhibitors and anti - hypertensives , in fact adversely affect immune development and functions and are most likely also deleterious to microbiota .
 None
Given options, please tell me the categories of all the listed entity words.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
 Entities:  
Answer:
 None