147
Mutations in ASPA that lead to loss of enzymatic activity have been identified , and E285A and Y231X are the two predominant mutations that account for 97 % of the mutant chromosomes in Ashkenazi Jewish patients .
 None
Given options, please tell me the categories of all the listed entity words.Output format is "type1: word1; type2: word2". 
Option: Disease 
Text: {0} 
 Entities:  
Answer:
 None