1977
Our results indicated that the mechanism of cell death involves cytochrome c release forming the apoptosome together with Apaf - 1 and caspase 9 , converting the caspase 9 into its active form , allowing it to activate caspase 3 as observed by immunofluorescence .
 None
Given options, please tell me the categories of all the listed entity words.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
 Entities:  
Answer:
 None