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Enhanced activity of topoisomerases in nuclear extracts upon translocation of VDR might reflect interaction of both within the nuclear compartment , thus initiating DNA-unwinding , a prerequisite of transcription initiation .
 protein: topoisomerases; protein: VDR
Given options, please tell me the categories of all the listed entity words.Output format is "type1: word1; type2: word2". 
Option: cell line, protein, RNA, DNA, cell type 
Text: {0} 
 Entities: topoisomerases, VDR 
Answer:
 protein: topoisomerases; protein: VDR