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After induction of general anesthesia and administration of a standard dose of intravenous esmolol hydrochloride , her cardiac rhythm progressed to asystole .
 asystole, esmolol hydrochloride
Please list all entity pairs containing a certain relationship in the given options.Output format is "word1, word2; word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 asystole, esmolol hydrochloride