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DISCUSSION : The main adverse effects of leflunomide consist of diarrhea , nausea , liver enzyme elevation , hypertension , alopecia , and allergic skin reactions .
 allergic skin reactions, leflunomide; alopecia, leflunomide; diarrhea, leflunomide; hypertension, leflunomide; liver enzyme elevation, leflunomide; nausea, leflunomide
Please list all entity pairs containing a certain relationship in the given options.Output format is "word1, word2; word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 allergic skin reactions, leflunomide; alopecia, leflunomide; diarrhea, leflunomide; hypertension, leflunomide; liver enzyme elevation, leflunomide; nausea, leflunomide