2585
We report the case histories of two patients with histologically confirmed adenocarcinoma of the prostate, both of whom had been treated with steroidal anti-androgen therapy in the form of cyproterone acetate prior to radical or palliative pelvic irradiation, and who subsequently developed femoral head avascular necrosis.
 two patients with histologically confirmed adenocarcinoma of the prostate: Subject; two: Subject.Population; femoral head avascular necrosis.: Effect; steroidal anti-androgen therapy in the form of cyproterone acetate prior to radical or palliative pelvic irradiation: Treatment; adenocarcinoma of the prostate: Treatment.Disorder; cyproterone acetate: Treatment.Drug
Given event type and trigger, please tell me the arguments of all the listed option. Output format is "name1: role1; name2: role2". 
Event type: adverse event 
  Option: Treatment.Freq, Subject.Population, Combination.Drug, Subject.Gender, Treatment.Duration, Subject, Effect, Treatment, Treatment.Disorder, Subject.Disorder, Treatment.Route, Subject.Race, Treatment.Time_elapsed, Treatment.Dosage, Subject.Age, Treatment.Drug 
Text: {0} 
Answer:
 two patients with histologically confirmed adenocarcinoma of the prostate: Subject; two: Subject.Population; femoral head avascular necrosis.: Effect; steroidal anti-androgen therapy in the form of cyproterone acetate prior to radical or palliative pelvic irradiation: Treatment; adenocarcinoma of the prostate: Treatment.Disorder; cyproterone acetate: Treatment.Drug