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A 64 year old man with recurrent metastatic squamous cell carcinoma of the head and neck developed severe skin rash and bone marrow aplasia 4 and 7 days, respectively, following a single dose of 40 mg/m2 methotrexate (MTX).
 A 64 year old man with recurrent metastatic squamous cell carcinoma of the head and neck: Subject; 64 year old: Subject.Age; man: Subject.Gender; skin rash and bone marrow aplasia: Effect; a single dose of 40 mg/m2 methotrexate (MTX): Treatment; recurrent metastatic squamous cell carcinoma of the head and neck: Treatment.Disorder; 40 mg/m2: Treatment.Dosage; methotrexate: Treatment.Drug; a single dose: Treatment.Freq; 4 and 7 days: Treatment.Time_elapsed
Given event type and trigger, please tell me the arguments of all the listed option. Output format is "name1: role1; name2: role2". 
Event type: adverse event 
  Option: Treatment.Freq, Subject.Population, Combination.Drug, Subject.Gender, Treatment.Duration, Subject, Effect, Treatment, Treatment.Disorder, Subject.Disorder, Treatment.Route, Subject.Race, Treatment.Time_elapsed, Treatment.Dosage, Subject.Age, Treatment.Drug 
Text: {0} 
Answer:
 A 64 year old man with recurrent metastatic squamous cell carcinoma of the head and neck: Subject; 64 year old: Subject.Age; man: Subject.Gender; skin rash and bone marrow aplasia: Effect; a single dose of 40 mg/m2 methotrexate (MTX): Treatment; recurrent metastatic squamous cell carcinoma of the head and neck: Treatment.Disorder; 40 mg/m2: Treatment.Dosage; methotrexate: Treatment.Drug; a single dose: Treatment.Freq; 4 and 7 days: Treatment.Time_elapsed