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In this article, we describe another case of subcutaneous changes following repeated glatiramer acetate injection, presented as localized panniculitis in the area around the injection sites, in a 46-year-old female patient who was treated with glatiramer acetate for 18 months.
 a 46-year-old female patient: Subject; 46-year-old: Subject.Age; female: Subject.Gender; subcutaneous changes: Effect; presented as localized panniculitis in the area around the injection sites: Effect; repeated glatiramer acetate injection: Treatment; glatiramer acetate: Treatment.Drug; injection: Treatment.Route
Given event type and trigger, please tell me the arguments of all the listed option. Output format is "name1: role1; name2: role2". 
Event type: adverse event 
  Option: Treatment.Freq, Subject.Population, Combination.Drug, Subject.Gender, Treatment.Duration, Subject, Effect, Treatment, Treatment.Disorder, Subject.Disorder, Treatment.Route, Subject.Race, Treatment.Time_elapsed, Treatment.Dosage, Subject.Age, Treatment.Drug 
Text: {0} 
Answer:
 a 46-year-old female patient: Subject; 46-year-old: Subject.Age; female: Subject.Gender; subcutaneous changes: Effect; presented as localized panniculitis in the area around the injection sites: Effect; repeated glatiramer acetate injection: Treatment; glatiramer acetate: Treatment.Drug; injection: Treatment.Route