2894
A 53-year-old man developed lower leg edema 4 weeks after rosiglitazone was increased from 4 mg once/day to 4 mg twice/day.
 A 53-year-old man: Subject; 53-year-old: Subject.Age; man: Subject.Gender; lower leg edema: Effect; 4 weeks after rosiglitazone was increased from 4 mg once/day to 4 mg twice/day: Treatment; 4 weeks: Treatment.Time_elapsed; rosiglitazone: Treatment.Drug; 4 mg: Treatment.Dosage; twice/day: Treatment.Freq
Given event type and trigger, please tell me the arguments of all the listed option. Output format is "name1: role1; name2: role2". 
Event type: adverse event 
  Option: Treatment.Freq, Subject.Population, Combination.Drug, Subject.Gender, Treatment.Duration, Subject, Effect, Treatment, Treatment.Disorder, Subject.Disorder, Treatment.Route, Subject.Race, Treatment.Time_elapsed, Treatment.Dosage, Subject.Age, Treatment.Drug 
Text: {0} 
Answer:
 A 53-year-old man: Subject; 53-year-old: Subject.Age; man: Subject.Gender; lower leg edema: Effect; 4 weeks after rosiglitazone was increased from 4 mg once/day to 4 mg twice/day: Treatment; 4 weeks: Treatment.Time_elapsed; rosiglitazone: Treatment.Drug; 4 mg: Treatment.Dosage; twice/day: Treatment.Freq