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The polycystic changes disappeared from the ovaries in 2 of the women after valproate therapy was discontinued, and the 2 women who had gained weight and developed amenorrhea while being treated with valproate lost weight and resumed menstruating after the change in medication.
 2 of the women: Subject; 2: Subject.Population; women: Subject.Gender; polycystic changes disappeared from the ovaries: Effect; lost weight and resumed menstruating: Effect; after valproate therapy was discontinued: Treatment; valproate: Treatment.Drug
Given event type and trigger, please tell me the arguments of all the listed option. Output format is "name1: role1; name2: role2". 
Event type: potential therapeutic event 
  Option: Treatment.Freq, Subject.Population, Combination.Drug, Subject.Gender, Treatment.Duration, Subject, Effect, Treatment, Treatment.Disorder, Treatment.Time_elapsed, Subject.Disorder, Subject.Race, Treatment.Route, Treatment.Dosage, Subject.Age, Treatment.Drug 
Text: {0} 
Answer:
 2 of the women: Subject; 2: Subject.Population; women: Subject.Gender; polycystic changes disappeared from the ovaries: Effect; lost weight and resumed menstruating: Effect; after valproate therapy was discontinued: Treatment; valproate: Treatment.Drug