507
We describe the clinical response, as determined by increases in total Hb and decreased transfusion needs, in five patients with thalassemia intermedia treated with HU alone or in combination with SPB.
 in five patients with thalassemia intermedia: Subject; five: Subject.Population; increases in total Hb and decreased transfusion needs: Effect; HU alone or in combination with SPB: Treatment; HU: Treatment.Drug; SPB: Treatment.Drug; thalassemia intermedia: Treatment.Disorder; HU: Combination.Drug; SPB: Combination.Drug
Given event type and trigger, please tell me the arguments of all the listed option. Output format is "name1: role1; name2: role2". 
Event type: potential therapeutic event 
  Option: Treatment.Freq, Subject.Population, Combination.Drug, Subject.Gender, Treatment.Duration, Subject, Effect, Treatment, Treatment.Disorder, Treatment.Time_elapsed, Subject.Disorder, Subject.Race, Treatment.Route, Treatment.Dosage, Subject.Age, Treatment.Drug 
Text: {0} 
Answer:
 in five patients with thalassemia intermedia: Subject; five: Subject.Population; increases in total Hb and decreased transfusion needs: Effect; HU alone or in combination with SPB: Treatment; HU: Treatment.Drug; SPB: Treatment.Drug; thalassemia intermedia: Treatment.Disorder; HU: Combination.Drug; SPB: Combination.Drug