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DISCUSSION: Methotrexate-induced papular eruption is rarely reported shortly after beginning methotrexate therapy in patients with acute exacerbation of collagen vascular diseases.
 patients with acute exacerbation of collagen vascular diseases: Subject; acute exacerbation of collagen vascular diseases: Subject.Disorder; papular eruption: Effect; Methotrexate: Treatment; Methotrexate: Treatment.Drug; shortly after: Treatment.Time_elapsed
Given event type and trigger, please tell me the arguments of all the listed option. Output format is "name1: role1; name2: role2". 
Event type: adverse event 
  Option: Treatment.Freq, Subject.Population, Combination.Drug, Subject.Gender, Treatment.Duration, Subject, Effect, Treatment, Treatment.Disorder, Subject.Disorder, Treatment.Route, Subject.Race, Treatment.Time_elapsed, Treatment.Dosage, Subject.Age, Treatment.Drug 
Text: {0} 
Answer:
 patients with acute exacerbation of collagen vascular diseases: Subject; acute exacerbation of collagen vascular diseases: Subject.Disorder; papular eruption: Effect; Methotrexate: Treatment; Methotrexate: Treatment.Drug; shortly after: Treatment.Time_elapsed