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The PON1192 genotype significantly modified the effect of age on paraoxonase ( POase ) activity ( p < 0 . 0001 ) such that increases in enzyme activity with age were influenced by the number of R alleles in a dose - dependent manner .
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Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Anatomy 
Text: {0} 
Answer:
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