1523
A method for the simultaneous determination of de ( N - methyl ) - N - ethyl - 8 , 9 - anhydroerythromycin A 6 , 9 - hemiacetal ( EM523 , I ) and its three metabolites in human plasma and urine has been developed using high - performance liquid chromatography ( HPLC ) with chemiluminescence ( CL ) detection .
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Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: GENE 
Text: {0} 
Answer:
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