22441
Recent studies suggest that the mammalian target of rapamycin and its downstream 70 - kDa ribosomal S6 kinase 1 negatively modulate the insulin - signaling pathway , which is considered the main cause of insulin resistance .
 Chemical: rapamycin
Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
 Chemical: rapamycin