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The Thr161Val mutation causes a lethal phenotype in the fission yeast Schizosaccharomyces pombe , while replacement of Thr161 with glutamic acid , potentially mimicking phosphorylation , causes uncoordination of mitosis and multiple cytokinesis .
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Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: GENE 
Text: {0} 
Answer:
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