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The A305E missense mutation accounted for 48 % ( 24 / 50 ) of mutant chromosomes in patients of western European descent , while the two predominant Jewish mutations each accounted for a single mutant chromosome .
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Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Disease 
Text: {0} 
Answer:
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