766
Here , we report that a mutation predicting the substitution of Gly 230 by glutamic acid ( G230E ) between segments D3 and D4 dramatically alters the pore properties of a recombinant human muscle Cl - channel ( hCIC - 1 ) expressed in a mammalian cell line ( tsA201 ) .
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Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Disease 
Text: {0} 
Answer:
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