693
Mutations in the COL3A1 gene have been implicated as a cause of type IV Ehlers - Danlos syndrome , a disease leading to aortic rupture in early adult life .
 Disease: type IV Ehlers - Danlos syndrome; Disease: aortic rupture
Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Disease 
Text: {0} 
Answer:
 Disease: type IV Ehlers - Danlos syndrome; Disease: aortic rupture