14649
The V600E mutation in the kinase BRAF is frequently detected in melanomas and results in constitutive activation of BRAF , which then promotes cell proliferation by the mitogen - activated protein kinase signaling pathway .
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Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
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