26487
Studies with transgenic mice with an early postnatal conditional hepatocyte - specific knockout of the beta - catenin gene Ctnnb1 revealed that beta - catenin deficiency decreases the magnitude of induction of drug - metabolizing enzymes by CAR activators , abrogates zonal differences in the hepatocytes ' susceptibility to these compounds , and impacts on hepatocyte proliferation .
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Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
 None