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One trial ( idebenone treatment of Leber hereditary optic neuropathy ) did not show significant improvement in the primary outcome , but there was significant improvement in a subgroup of patients .
 Chemical: idebenone
Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
 Chemical: idebenone