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Correlations with much better predictive abilities are achieved when the volume of the solute is used as additional variable , which illustrates the main roles of both lipophilicity and size of the solute to penetrate through the skin .
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Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
 None