29427
The discovery that GPC1 and GPC3 regulate BMP2 - mediated osteogenesis , and that inhibition of endogenous GPC1 and GPC3 potentiates BMP2 responsiveness of human suture mesenchymal cells , indicates how downregulation of glypican expression could lead to the bony suture fusion that characterizes craniosynostosis .
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Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
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