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Currently available methods to produce CpG - methylated plasmid DNA have certain limitations and cannot generate large quantities of methylated DNA without cost or problems of purity .
 Anatomy: plasmid
Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Anatomy 
Text: {0} 
Answer:
 Anatomy: plasmid