5342
Here we show that primary HGPS skin fibroblasts experience genome - wide correlated alterations in patterns of H3K27me3 deposition , DNA - lamin A / C associations , and , at late passages , genome - wide loss of spatial compartmentalization of active and inactive chromatin domains .
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Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
 None