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Telomeric quadruplex stabilization by small molecules can lead to telomere uncapping , followed by DNA damage response and senescence , as well as chromosomal fusions leading to deregulation of mitosis , followed by apoptosis and downregulation of oncogene expression .
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Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
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