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As very rare variants constitute the majority of variants identified in sequencing studies , these findings suggest that careful attention need to be placed on the plausible relationship that exist between very rare variants and common disease . European Journal of Human Genetics advance online publication , 16 January 2013 ; doi : 10 . 1038 / ejhg . 2012 . 284 .
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Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
 None