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Past studies have documented a crosstalk between H2B ubiquitylation ( H2Bub ) and H3K4 methylation , but little ( if any ) direct evidence exists explaining the mechanism underlying H2Bub - dependent H3K4 methylation on chromatin templates .
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Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
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