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We validate our approach by screening combinations of cellulases with real - world insoluble substrates , and demonstrate that the chip - based screening is in excellent agreement with the conventional screening methods , while offering advantages of throughput , speed and lower reagent consumption .
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Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
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