16353
We identified depleted PK - M2 ( M2 isoform of pyruvate kinase ) activity and apoptosis of NPCs revealed by the genomic DNA fragmentation and elevated PARP ( poly ADP ribose polymerase ) activity along with increased Caspase activity initiated by severely depolarised mitochondrial membranes .
 Chemical: pyruvate; Chemical: poly ADP ribose
Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
 Chemical: pyruvate; Chemical: poly ADP ribose