25695
Molecular dynamics simulations conducted with the truncated and homology models of the fully length BoNT LC / A indicate the flexibility of the C - terminus of the full length enzyme is responsible for the potency shifts of active - site proximally binding inhibitors while distal binding ( alpha - exosite ) inhibitors remain equipotent .
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Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
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Answer:
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