21453
Polymorphisms in CYP2D6 and CYP2C19 affect the efficacy and safety of tricyclics , with some drugs being affected by CYP2D6 only , and others by both polymorphic enzymes .
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Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
 None