210
Diltiazem decreased the total body clearance from 34 . 0 + / - 8 . 0 to 28 . 6 + / - 6 . 1 mL / min ( P less than . 01 ) , and prolonged the elimination half - life from 12 . 6 + / - 3 . 0 to 14 . 3 + / - 2 . 5 hours ( P less than . 01 ) of antipyrine without any changes in volume of distribution .
 None
Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: GENE 
Text: {0} 
Answer:
 None