1399
At 100 nM total estradiol , a concentration achievable during the third trimester of pregnancy , CYP2B6 activity was predicted to increase by 1 . 5 - 3 - fold , based on increased CYP2B6 activity and mRNA .
 Chemical: estradiol
Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
 Chemical: estradiol