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To avoid some of these shortcomings while retaining the desired attributes of the carboxylic acid moiety , medicinal chemists often investigate the use of carboxylic acid ( bio ) isosteres .
 Chemical: carboxylic acid; Chemical: carboxylic acid
Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
 Chemical: carboxylic acid; Chemical: carboxylic acid