28495
Taken together , statins , via ERK5 activation , suppress TNF - stimulated Rac - 1 activation , ROS generation , NF - kappa B activation and VCAM - 1 and ICAM - 1 expression in human ECs , which provides a novel explanation for the pleiotropic effects of statins that benefit the cardiovascular system .
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Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
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