4193
Thus , SQSTM1 - mediated dysregulation of the Keap1 - Nrf2 axis , which could potentially lead to aberrant production of oxidative response genes , may contribute to disease aetiology in a subset of PDB patients .
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Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
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