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ErbB2 is frequently highly expressed in premalignant breast cancers , including ductal carcinoma in situ ( DCIS ) ; however , little is known about the signals or pathways it contributes to progression into the invasive / malignant state .
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Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
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