22656
The primary endpoints were ( 1 ) the best response to initial therapy defined as either remission ( stimulated Tg < 1 ng / mL , negative US ) , or persistent disease ( biochemical and / or structural ) and ( 2 ) clinical status at final follow - up defined as either no evidence of disease ( suppressed Tg < 1 ng / mL , negative US ) , biochemical persistent disease ( suppressed Tg > 1 ng / mL in the absence of structural disease ) , structural persistent disease ( loco - regional or distant metastases ) or recurrence ( biochemical or structural disease identified after a period of no evidence of disease , NED ) .
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Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
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