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Although it has been reported that deficiency of toll - like receptor 4 ( TLR4 ) is associated with reduced atherosclerosis in atherosclerosis - prone mice and attenuated pro - inflammatory state in diabetic mice , it remains undetermined whether treatment with a TLR4 antagonist reduces atherosclerosis in nondiabetic or diabetic mice that have TLR4 expression .
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Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
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