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Here , we review the tumor promoting function of TGF - beta and its possible promise as a therapeutic target in high grade gliomas , including glioblastoma multiforme ( GBM ) , a disease with very poor prognosis .
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Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
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