1998
In the budding yeast , Saccharomyces cerevisiae , replicators can function outside the chromosome as autonomously replicating sequence ( ARS ) elements ; however , within chromosome III , certain ARSs near the transcriptionally silent HML locus show no replication origin activity .
 GENE: HML locus
Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: GENE 
Text: {0} 
Answer:
 GENE: HML locus