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Screening of compounds interacting with GPCRs has developed during the past decade from receptor binding assays , to various functional determination of coupling to G - proteins , and , more recently , G - protein - independent signal transduction events .
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Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
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