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The association of the K variant with AD in a controversial manner in different surveys is probably caused by its linkage disequilibrium with - 116A that , by reducing BChE activity , potentially increases cholinergic transmission in comparison with usual genotypes .
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Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
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