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These results suggest that chronic nicotine - treated rats develop locomotor hyperactivity in response to nicotine initially due to increases of both the density of nicotinic receptors and DA concentration , followed by inducing DA receptor supersensitivity in the striatum .
 Chemical: nicotine; Disease: locomotor hyperactivity; Chemical: nicotine; Chemical: DA; Chemical: DA
Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Disease, Chemical 
Text: {0} 
Answer:
 Chemical: nicotine; Disease: locomotor hyperactivity; Chemical: nicotine; Chemical: DA; Chemical: DA