18476
Because of the low susceptibility of this fungus to antifungal drugs , and the low permeability of the blood - brain barrier ( BBB ) , therapeutic drug monitoring is necessary to reach an effective tissue concentration with limited side effects .
 None
Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
 None