5341
This mutation activates a cryptic splice donor site in exon 11 , and leads to an in - frame deletion within the prelamin A mRNA and the production of a dominant - negative lamin A protein , known as progerin .
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Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
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