20543
The purpose of this review is to discuss the latest knowledge concerning GPER modulation of cardiovascular function , with a particular emphasis upon how activation of this receptor could mediate acute estrogen effects in the heart and blood vessels ( i . e . , vascular tone , cell growth and differentiation , apoptosis , endothelial function , myocardial protection ) .
 Chemical: estrogen
Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
 Chemical: estrogen