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Subsequent molecular biology , biosynthetic , and immunofluorescence studies demonstrated that C2 secretion is impaired in Type II C2 deficiency because of different missense mutations at highly conserved residues in each of the C2Q0 alleles .
 Disease: Type II C2 deficiency
Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Disease 
Text: {0} 
Answer:
 Disease: Type II C2 deficiency