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In three unrelated Japanese children with combined pituitary hormone deficiency , we identified three point mutations in the Pit-1 gene , Pro24Leu , Arg143Gln , and Arg271Trp , located on the major transactivation region , POU-specific domain , and POU-homeodomain , respectively.
 DNA: Arg271Trp; DNA: POU-specific domain; DNA: Arg143Gln; DNA: POU-homeodomain; DNA: Pit-1 gene; protein: Pit-1; DNA: major transactivation region; DNA: Pro24Leu
Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: cell line, protein, RNA, DNA, cell type 
Text: {0} 
Answer:
 DNA: Arg271Trp; DNA: POU-specific domain; DNA: Arg143Gln; DNA: POU-homeodomain; DNA: Pit-1 gene; protein: Pit-1; DNA: major transactivation region; DNA: Pro24Leu