2249
They also negatively modulate the PI 3 - kinase catalytic activity but to different extents , dependent on the unique N - terminal structure of each isoform .
 GENE: PI 3 - kinase
Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: GENE 
Text: {0} 
Answer:
 GENE: PI 3 - kinase