1390
The mechanism involves Gbetagamma subunit - mediated increases in tyrosine phosphorylation of the Shc adapter protein , Shc * Grb2 complex formation , and recruitment of Ras guanine nucleotide exchange factor activity .
 GENE: Gbetagamma; GENE: Shc adapter protein; GENE: Shc; GENE: Grb2; GENE: Ras guanine nucleotide exchange factor
Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: GENE 
Text: {0} 
Answer:
 GENE: Gbetagamma; GENE: Shc adapter protein; GENE: Shc; GENE: Grb2; GENE: Ras guanine nucleotide exchange factor