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Codon 344 is a key residue within the tetramerisation domain , and the amino acid substitution of a proline for a leucine is predicted to have profound implications for tetramerisation and potentially DNA binding .
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Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Disease 
Text: {0} 
Answer:
 None