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By detailed phenotypic analysis of our patients , and by critical literature review , we found that homozygous TRAPPC9 loss - of - function mutations cause a distinctive phenotype , characterized by peculiar facial appearance , obesity , hypotonia ( all signs resembling a Prader - Willi - like phenotype ) , moderate - to - severe ID , and consistent brain abnormalities .
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Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
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