22987
These results indicate that OPE may have anti - thrombotic effects through restricting the induced expression of tissue factor via down - regulating mitogen - activated protein kinase ( MAPK ) activation upon coagulation stimulus , leading to the prolongation of time for arterial thrombosis .
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Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
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