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This article aims to review qualitative and quantitative differences in drug metabolizing enzymes in neonates , since both phase I and phase II metabolic pathways are immature at birth and subject to maturational changes in the first period of extrauterine life .
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Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
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