6710
Here we show that NEDD4 - 1 is a novel E3 ligase that specifically regulates ubiquitin - dependent trafficking of pAKT in insulin - like growth factor ( IGF ) - 1 signaling .
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Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
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