8196
Structure - activities studies guided optimization of a lead compound , identified through high - throughput screening , gave rise to sub - nanomolar inhibitors of human sEH with stability in human liver microsomal assay suitable for preclinical development .
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Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
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