18322
In conclusion , impaired activity of SIRT1 induces endothelial dysfunction and up - regulates NADPH oxidase - derived ROS production in the vascular wall , mimicking the vascular aging phenotype .
 Chemical: NADPH
Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
 Chemical: NADPH