1642
Null mutations in daf - 3 suppress mutations in genes encoding this TGF - beta signal , its receptors , and associated Smad signal transduction proteins . daf - 3 encodes a Smad protein that is most closely related to mammalian DPC4 , and is expressed throughout development in many of the tissues that are remodeled during dauer development .
 GENE: daf - 3; GENE: TGF - beta; GENE: Smad signal transduction proteins; GENE: daf - 3; GENE: Smad protein; GENE: mammalian DPC4
Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: GENE 
Text: {0} 
Answer:
 GENE: daf - 3; GENE: TGF - beta; GENE: Smad signal transduction proteins; GENE: daf - 3; GENE: Smad protein; GENE: mammalian DPC4