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As the result , we have found that the inhibitor showed about 13 - fold lowered IC50 value compared with that of the corresponding monovalent peptide , thereby activating HIF - 1 alpha and leading to up - regulation of VEGF protein at the cellular level .
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Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
 None