2578
The objective of this study was to show that the blood - brain barrier ( BBB ) , through a combination of tight junctions and active efflux transporters in the brain microvasculature , can significantly restrict delivery of molecularly targeted agents to invasive glioma cells .
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Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
 None