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Together , our data unravel novel roles for CTSK in macrophage - regulated processes , and provide evidence for close interplay between inflammatory , osteolytic and tumor cell - driven events in the bone - tumor microenvironment .
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Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
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