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The sirtuin - catalyzed deacetylation reaction has captured tremendous interest during the past a few years because of ( i ) its increasingly demonstrated importance in many crucial biological processes such as gene transcription , metabolism , and aging , and thus its therapeutic potential for metabolic and age - related diseases and cancer , and ( ii ) its unique deacetylation chemistry .
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Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
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