4500
They are homozygous for a point mutation at codon 307 ( CTT --> CCT ) resulting in the substitution of leucine 307 by proline .
 Chemical: leucine; Chemical: proline
Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
 Chemical: leucine; Chemical: proline