28574
Crosslinking S5 and S2 , which not only restricts S5 ' s lateral movement , but also prevents substrate from passing between the two helices , does not hinder the protease ' s ability to cleave a membrane protein substrate in detergent solution and in reconstituted membrane vesicles .
 None
Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
 None