8243
Treatment of Caco - 2 cells with 50 mu g / ml alkaloid extract and 50 mu M chelidonine for up to 48 h resulted in a significant decrease in mRNA levels of P - gp / MDR1 , MRP1 , BCRP , CYP3A4 , GST , and hPXR and in a significant increase in caspase - 3 and caspase - 8 mRNA .
 Chemical: chelidonine
Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
 Chemical: chelidonine