18338
Using cultured human keratinocytes and diabetic rat model , the current study showed that high - glucose environment enhanced IL - 8 production via epidermal growth factor receptor ( EGFR ) - extracelluar signal - regulated kinase ( ERK ) pathway in a reactive oxygen species ( ROS ) - dependent manner in keratinocytes .
 Chemical: glucose; Chemical: oxygen
Please list all entity words in the text that fit the category.Output format is "type1: word1; type2: word2". 
Option: Chemical 
Text: {0} 
Answer:
 Chemical: glucose; Chemical: oxygen