18087
Moreover , the calculations show that the DAPI molecule , when minor groove bound to the nucleic acid , presents both a reduced geometrical flexibility because of the rigid DNA pocket and a reduced polarization due to the very " apolar " microenvironment .
 DAPI
Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: Chemical 
Text: {0} 
Answer:
 DAPI