17040
Following structure - activity relationship studies in vitro , a number of compounds were identified as potent TRPM8 antagonists and were subsequently evaluated in an in vivo pharmacodynamic assay of icilin - induced ' wet - dog ' shaking in which compound 12 was fully effective .
 icilin
Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: Chemical 
Text: {0} 
Answer:
 icilin