3453
These data provide the first demonstration in vivo that activation of a protein phosphatase can inactivate I kappa B , and suggest one possible explanation for mechanism-based toxicities associated with FK-506 and CsA by demonstrating that these drugs can inhibit the calcineurin -dependent activation of a virtually ubiquitous transcription factor .
 ubiquitous transcription factor, I kappa B, protein phosphatase, calcineurin
Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: cell line, protein, RNA, DNA, cell type 
Text: {0} 
Answer:
 ubiquitous transcription factor, I kappa B, protein phosphatase, calcineurin