3315
Two siblings with hemolytic anemia caused by triosephosphate isomerase deficiency developed a progressive neurological syndrome featuring dystonic movements , tremor , pyramidal tract signs , and evidence of spinal motor neuron involvement .
 triosephosphate isomerase
Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: GENE 
Text: {0} 
Answer:
 triosephosphate isomerase