4677
Thus , these results together suggest that sunitinib initially exerts its apoptotic effect through the inhibition of VEGFR - 2 , which , when followed by reduction of its downstream effectors , including Akt / mTOR / S6K1 , may lead to inhibition of the antiapoptotic molecule Bcl - 2 and activation of the proapoptotic molecule BAD in PC12 cells .
 PC12 cells
Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: Anatomy 
Text: {0} 
Answer:
 PC12 cells