1946
Tub is a substrate of insulin receptor tyrosine kinase ( IRTK ) and leptin receptor ( LEPR ) - Janus kinase 2 ( JAK2 ) in hypothalamic nuclei .
 tyrosine
Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: Chemical 
Text: {0} 
Answer:
 tyrosine