21267
Excess lipids in peripheral tissues - skeletal muscle , liver and adipose tissue - may attenuate insulin signaling through the protein kinase B ( AKt ) pathway and up - regulate protein tyrosine phosphatase 1B ( PTP1B ) , a negative regulator of insulin signaling .
 tyrosine
Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: Chemical 
Text: {0} 
Answer:
 tyrosine