11877
Based on this analysis , we propose that the interactions of Sos with the switch 1 and switch 2 regions of Ras have distinct functional consequences : the interaction with switch 2 mediates the anchoring of Ras to Sos , whereas the interaction with switch 1 leads to disruption of the nucleotide - binding site and GDP dissociation .
 Sos, Ras, Ras, Sos
Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: GENE 
Text: {0} 
Answer:
 Sos, Ras, Ras, Sos