1494
Both classical analgesics ( nonsteroidal anti - inflammatory drugs , opioid drugs ) and many analgesic adjuvants , including desipramine , duloxetine , fluoxetine , paroxetine , escitalopram , phenytoin or carbamazepine and alpha - lipoic acid can modulate the balance between pro - oxidant and antioxidant processes in the mammalian tissues and these properties of drugs such as indomethacin , meloxicam , tenoxicam , valdecoxib or some metabolites of analgesic drugs formed by the activity of tissue peroxidases may contribute to their clinical efficacy and drug - related toxic effects , including gastrointestinal ulcers , hepatic failure , agranulocytosis , aplastic anemia , neutropenia , opiate - induced hyperalgesia and tolerance .
 desipramine, duloxetine, fluoxetine, paroxetine, escitalopram, phenytoin, carbamazepine, alpha - lipoic acid, indomethacin, meloxicam, tenoxicam, valdecoxib
Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: Chemical 
Text: {0} 
Answer:
 desipramine, duloxetine, fluoxetine, paroxetine, escitalopram, phenytoin, carbamazepine, alpha - lipoic acid, indomethacin, meloxicam, tenoxicam, valdecoxib