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Polybrominated diphenyl ethers ( PBDEs ) have been shown to affect the estrogen receptor ( ER ) signaling pathway , and one of the proposed disruption mechanisms is direct binding of hydroxylated PBDE ( OH - PBDE ) to ER .
 Polybrominated diphenyl ethers, PBDEs, estrogen, PBDE, OH - PBDE
Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: Chemical 
Text: {0} 
Answer:
 Polybrominated diphenyl ethers, PBDEs, estrogen, PBDE, OH - PBDE