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In this review , we examine computational efforts made towards modeling and simulation of ( i ) the complex behavior of membrane lipids , ( ii ) membrane lipid - GPCR interactions as well as membrane lipid - mediated effects on GPCRs and ( iii ) GPCR oligomerization in a native - like membrane environment .
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Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: Chemical 
Text: {0} 
Answer:
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