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Apoptosis was also further confirmed by DNA fragmentation analysis . Furthermore , HCE inhibited migration of human umbilical vein endothelial cells as well as decreased secretion of matrix metalloproteinase and vascular endothelial growth factor . In conclusion , the present study has assessed the in vitro antiproliferative / antiangiogenic potential of HCE .
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Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: Chemical 
Text: {0} 
Answer:
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