88865
The crucial test result ( in a murine model of " Streptococcus pyogenes " systemic infection ) that preliminarily established the antibacterial efficacy of Prontosil in mice dates from late December 1931 .
 Streptococcus pyogenes
Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: media, plant, vehicle, astronomical object, time, disease, animal, location, person, organization, mythical figure, food, biology, geographical phenomenon, instrument, event 
Text: {0} 
Answer:
 Streptococcus pyogenes