4346
Treatment of previously treated metastatic breast cancer by mitoxantrone and 48 - hour continuous infusion of high - dose 5 - FU and leucovorin ( MFL ) : low palliative benefit and high treatment - related toxicity .
 breast cancer, mitoxantrone, 5 - FU, leucovorin, MFL, toxicity
Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: Disease, Chemical 
Text: {0} 
Answer:
 breast cancer, mitoxantrone, 5 - FU, leucovorin, MFL, toxicity