96346
The CRISPR / Cas9 system uses a short guide RNA ( sgRNA ) sequence to direct a " Streptococcus pyogenes " Cas9 nuclease , acting as a programmable DNA binding protein , to cleave DNA at a site of interest .
 Streptococcus pyogenes
Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: media, plant, vehicle, astronomical object, time, disease, animal, location, person, organization, mythical figure, food, biology, geographical phenomenon, instrument, event 
Text: {0} 
Answer:
 Streptococcus pyogenes