9250
Here we demonstrate that the mechanism of activation of HIF - 1alpha is a multi - step process which includes hypoxia - dependent nuclear import and activation ( derepression ) of the transactivation domain , resulting in recruitment of the CREB - binding protein ( CBP ) / p300 coactivator .
 HIF - 1alpha, CREB - binding protein, CBP, p300 coactivator
Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: GENE 
Text: {0} 
Answer:
 HIF - 1alpha, CREB - binding protein, CBP, p300 coactivator