751
Cleavage by the intron - encoded enzyme ( I - CreI ) occurs 5 bp and 1 bp 3 ' to the intron insertion site ( in the 3 ' - exon ) in the top ( / ) and bottom ( , ) strands , respectively , resulting in 4 - nt single - stranded overhangs with 3 ' - OH termini .
 I - CreI
Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: GENE 
Text: {0} 
Answer:
 I - CreI