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Using selective inhibitors , we investigated the signaling pathways involved in the CD28 -mediated induction of AP-1 and NF-kappaB .
 NF-kappaB, AP-1, CD28
Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: cell line, protein, RNA, DNA, cell type 
Text: {0} 
Answer:
 NF-kappaB, AP-1, CD28