4145
The second patient was a compound heterozygote , with a missense mutation , C1837 - - > T , changing the arginine at residue 613 to tryptophan on one allele and a single base deletion at the intron - exon 6 boundary as the second mutation .
 None
Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: Disease 
Text: {0} 
Answer:
 None