1749
Disruption of the IRA2 gene resulted in ( i ) increased sensitivity to heat shock and nitrogen starvation , ( ii ) sporulation defects , and ( iii ) suppression of the lethality of the cdc25 mutant .
 IRA2 gene, cdc25 mutant
Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: GENE 
Text: {0} 
Answer:
 IRA2 gene, cdc25 mutant