11869
Reactive oxygen species ( ROS ) such as hydrogen peroxide serve as second messengers in the induction of the transcription factor NF-kappaB , and hence in the activation and replication of human immunodeficiency virus type 1 ( HIV-1 ) in human cells .
 transcription factor, human cells, NF-kappaB
Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: cell line, protein, RNA, DNA, cell type 
Text: {0} 
Answer:
 transcription factor, human cells, NF-kappaB