5861
These data demonstrate that 1 , 25 - dihydroxyvitamin D stimulates adipose leptin production in a VDR - dependent manner , suggesting that vitamin D may affect energy homeostasis through direct regulation of leptin expression .
 1 , 25 - dihydroxyvitamin D, vitamin D
Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: Chemical 
Text: {0} 
Answer:
 1 , 25 - dihydroxyvitamin D, vitamin D