14870
Various strategies such as anti - IGF - 1R antibodies , IGF - 1 mimetic peptides , antisense strategies , IGF - 1R specific peptide aptamers , targeted degradation of IGF - 1R and expression of dominant negative IGF - 1R mutants have been explored to inhibit the IGF - 1R signaling .
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Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: Chemical 
Text: {0} 
Answer:
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