9089
POU - domain proteins , such as the pituitary - specific factor Pit - 1 , are members of the homeodomain family of proteins which are important in development and homeostasis , acting constitutively or in response to signal - transduction pathways to either repress or activate the expression of specific genes .
 POU - domain proteins, pituitary - specific factor Pit - 1, homeodomain family
Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: GENE 
Text: {0} 
Answer:
 POU - domain proteins, pituitary - specific factor Pit - 1, homeodomain family