16049
A series of indazolo [ 4 , 3 - gh ] isoquinolinones derivatives have been synthesized to decrease cardiotoxic side effects in comparison to Mitoxantrone .
 indazolo [ 4 , 3 - gh ] isoquinolinones, Mitoxantrone
Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: Chemical 
Text: {0} 
Answer:
 indazolo [ 4 , 3 - gh ] isoquinolinones, Mitoxantrone