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We performed an in vitro evaluation of the genotoxic potential of water extracts from four Hypoxis species ( Hypoxis hemerocallidea , H . colchicifolia , H . rigidula , H . acuminata ) and a commercial preparation thereof using the neutral red uptake ( NRU ) assay , the alkaline comet assay and the cytome assay in human hepatoma HepG2 cells .
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Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: Chemical 
Text: {0} 
Answer:
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