1675
As a consequence of blocking I ( f ) , clonidine reduced the slope of the diastolic depolarization and the frequency of pacemaker potentials in sinoatrial node cells from wild - type and alpha2ABC - knockout mice .
 clonidine
Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: Disease, Chemical 
Text: {0} 
Answer:
 clonidine