3455
Complete deficiency of hypoxanthine - guanine phosphoribosyltransferase ( HPRT ) causes the Lesch - Nyhan syndrome .
 deficiency of hypoxanthine - guanine phosphoribosyltransferase, Lesch - Nyhan syndrome
Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: Disease 
Text: {0} 
Answer:
 deficiency of hypoxanthine - guanine phosphoribosyltransferase, Lesch - Nyhan syndrome