12839
Despite inducing a decrease in PKB ( protein kinase B ) / Akt phosphorylation , spermidine promoted cell survival and opposed the anti - proliferative effects of PI3K inhibitors .
 spermidine
Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: Chemical 
Text: {0} 
Answer:
 spermidine