4452
Using MDA - MB - 231 cells , in which FOXO3a activity can be induced by 4 - hydroxytamoxifen , we showed that FOXO3a induction up - regulates PI3K - Akt activity and enhanced doxorubicin resistance .
 MDA - MB - 231 cells
Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: Anatomy 
Text: {0} 
Answer:
 MDA - MB - 231 cells