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These data demonstrate that 1 ) there is an identical 2 - base pair deletion in an exon of the C5 gene in several different C5 - deficient mouse strains ; 2 ) the mRNA transcribed from the C5D gene retains this deletion ; and 3 ) this mutation should result in C5 protein deficiency .
 C5 - deficient, C5 protein deficiency
Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: Disease 
Text: {0} 
Answer:
 C5 - deficient, C5 protein deficiency