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A literature search of the PubMed database was conducted to identify articles that described the molecular mechanisms of BCR - ABL1 - mediated leukemic transformation , the efficacy and safety of imatinib , nilotinib , dasatinib , and bosutinib in patients with CML , the kinase - binding spectrum of each TKI , and evidence suggesting a link between the TKI - binding profile and adverse events .
 imatinib, nilotinib, dasatinib, bosutinib
Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: Chemical 
Text: {0} 
Answer:
 imatinib, nilotinib, dasatinib, bosutinib