3933
No histopathological alterations or differences in bone formation were seen in the limbs or toes of any chicks from any group ; however , extensive cranial hemorrhage occurred in all nicotine sulfate - treated chicks .
 cranial hemorrhage, nicotine
Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: Disease, Chemical 
Text: {0} 
Answer:
 cranial hemorrhage, nicotine