12650
These observations suggest that protein glycation in pancreatic beta cells , which occurs in vivo under chronic hyperglycemia , suppresses insulin gene transcription and thus can explain part of the beta cell glucose toxicity .
 pancreatic beta cells
Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: cell line, protein, RNA, DNA, cell type 
Text: {0} 
Answer:
 pancreatic beta cells