10123
Single - nucleotide polymorphisms ( SNPs ) in the CYP2C gene cluster have been extensively investigated as predisposing factors for nonsteroidal anti - inflammatory drug ( NSAID ) - induced peptic ulcer disease ( PUD ) or upper gastrointestinal bleeding ( UGIB ) .
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Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: Chemical 
Text: {0} 
Answer:
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