20277
This cooperative activation of gene expression was enhanced by steroid receptor coactivator 3 coactivator , and required each ligand - bound subunit of the dimer to bind to DNA , as well as both activation function 1 domains for maximal transcriptional activity .
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Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: Chemical 
Text: {0} 
Answer:
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