1056
However , we report that combining these drugs with 5 - azadC results in a 2 - to 5 - fold increase in FMR1 mRNA levels obtained with 5 - azadC alone , thus showing a marked synergistic effect of histone hyperacetylation and DNA demethylation in the reactivation of FMR1 full mutations . .
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Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: Disease 
Text: {0} 
Answer:
 None