6481
IL-12 is a critical immunoregulatory cytokine that promotes cell-mediated immune responses and the differentiation of naive CD4+ cells to Th1 cells ; however, relatively few IL-12 target genes have been identified.
 Th1 cells, CD4+ cells, critical immunoregulatory cytokine, IL-12, IL-12
Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: cell line, protein, RNA, DNA, cell type 
Text: {0} 
Answer:
 Th1 cells, CD4+ cells, critical immunoregulatory cytokine, IL-12, IL-12