2548
The sG145R mutation strongly reduced HBsAg levels and was able to fully restore the impaired replication of LAM - resistant HBV mutants to the levels of wild - type HBV , and PC or BCP mutations further enhanced viral replication .
 HBsAg, LAM
Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: Disease, Chemical 
Text: {0} 
Answer:
 HBsAg, LAM