3550
Homozygous C2 deficiency in a 19 - year - old boy was associated with variable immunodeficiency manifested by marked hypoimmunoglobulinemia and impaired antibody responses , normal circulating B lymphocytes , and subnormal T - cell functions .
 C2 deficiency, immunodeficiency, hypoimmunoglobulinemia
Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: Disease 
Text: {0} 
Answer:
 C2 deficiency, immunodeficiency, hypoimmunoglobulinemia