385458
The US Food and Drug Administration ( FDA ) approved lomitapide on 21 December 2012 , as an orphan drug to reduce LDL cholesterol , total cholesterol , apolipoprotein B , and non-high-density lipoprotein ( non-HDL ) cholesterol in patients with homozygous familial hypercholesterolemia ( HoFH ) .
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Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: location, person, organization 
Text: {0} 
Answer:
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