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In this study , we quantified the mRNA level of GCH1 in phytohemagglutinin ( PHA ) - stimulated mononuclear blood cells from one Japanese family that do not have a mutation in the coding region or splice junctions of the gene .
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Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: Disease 
Text: {0} 
Answer:
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