10958
Altogether, our data demonstrate that: (a) the ability of B cells to release TNF-alpha after triggering of HLA-DR antigens depends on their stage of differentiation; (b) levels of released TNF-alpha seem to correlate with the stage of B-cell maturation but do not correlate with the amounts of cell surface HLA-DR antigens ; (c) secreted TNF-alpha regulates the levels of expression of NF-kappa B and AP-1 by an autocrine loop ; and (d) intracellular signals mediating TNF-alpha release by B cells are distinct from those regulating homotypic aggregation and proliferation .
 TNF-alpha, B cells, TNF-alpha, AP-1, cell surface HLA-DR antigens, B cells, NF-kappa B, HLA-DR antigens, TNF-alpha, TNF-alpha, HLA-DR antigens
Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: cell line, protein, RNA, DNA, cell type 
Text: {0} 
Answer:
 TNF-alpha, B cells, TNF-alpha, AP-1, cell surface HLA-DR antigens, B cells, NF-kappa B, HLA-DR antigens, TNF-alpha, TNF-alpha, HLA-DR antigens