11255
Moreover , Acrolein resulted in activation of astrocytes , up - regulation of BACE - 1 in cortex and down - regulation of ADAM - 10 in hippocampus and cortex .
 Acrolein
Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: Chemical 
Text: {0} 
Answer:
 Acrolein