14374
The transcription factor E2F activates the expression of multiple genes involved in cell proliferation , such as c-myc and the dihydrofolate reductase gene .
 dihydrofolate reductase gene, E2F, c-myc, transcription factor, genes
Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: cell line, protein, RNA, DNA, cell type 
Text: {0} 
Answer:
 dihydrofolate reductase gene, E2F, c-myc, transcription factor, genes