2553
In this study , to examine hypoxia - specific production of anti - angiogenic therapeutic gene , we constructed 5 copies of HRE ( 5xHRE ) of human VEGF linked to soluble Tie2 ( sTie2 ) driven by minimal SV40 promoter ( 5xHRE / SV40 / sTie2 ) .
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Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: Anatomy 
Text: {0} 
Answer:
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