8298
The substrate - dependent alterations in activities of CDA70Thr and DCK24Val in vitro were observed for the first time , and demonstrate that the in vivo consequences of these genetic variations should not be extrapolated from one substrate of these enzymes to another .
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Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: Chemical 
Text: {0} 
Answer:
 None