14433
However , due to their high cost and limited accessibility , these formulations are generally used as second - line antifungal therapy in cases of conventional AmB refractoriness and / or intolerance or pre - existing renal dysfunction .
 AmB
Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: Chemical 
Text: {0} 
Answer:
 AmB