11482
A marked decrease in the type 1 insulin - like growth factor ( IGF ) receptor ( IGF - IR ) occurs in prostate epithelial cells during transformation from the benign to the metastatic state .
 type 1 insulin - like growth factor ( IGF ) receptor, IGF - IR
Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: GENE 
Text: {0} 
Answer:
 type 1 insulin - like growth factor ( IGF ) receptor, IGF - IR