2842
We report here a 3 - base pair in - frame deletion of the PAH gene ( delta 194 ) in a mild variant , with markedly reduced affinity of the enzyme for phenylalanine ( Km = 160 nM ) , and we provide functional evidence for responsibility of the deletion in the mutant phenotype .
 None
Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: Disease 
Text: {0} 
Answer:
 None