5080
Data from the V - HeFT II show that at 2 - year follow - up , a progressive rise of plasma norepinephrine was observed in both treatment arms , suggesting that disease progresses despite treatment with either an angiotensin - converting enzyme inhibitor , enalapril , or vasodilator therapy with hydralazine / isosorbide dinitrate .
 angiotensin - converting enzyme
Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: GENE 
Text: {0} 
Answer:
 angiotensin - converting enzyme