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The objective of the first is the preservation of the cosmetic and functional integrity of the vulva in younger and sexually active patients , in whom a steady increase in the incidence of vulvar intraepithelial neoplasia has been observed in the last decade .
 vulvar intraepithelial neoplasia
Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: media, plant, vehicle, astronomical object, time, disease, animal, location, person, organization, mythical figure, food, biology, geographical phenomenon, instrument, event 
Text: {0} 
Answer:
 vulvar intraepithelial neoplasia