2047
Interestingly , adult transgenic mnd2 mice develop accelerated aging phenotypes , such as premature weight loss , hair loss , reduced fertility , curvature of the spine , heart enlargement , increased autophagy , and death by 12 - 17 months of age .
 None
Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: Chemical 
Text: {0} 
Answer:
 None