103125
Arsphenamine proved to be the first effective treatment for syphilis , a disease which prior to that time was incurable and led inexorably to severe skin ulceration , neurological damage , and death .
 syphilis
Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: media, plant, vehicle, astronomical object, time, disease, animal, location, person, organization, mythical figure, food, biology, geographical phenomenon, instrument, event 
Text: {0} 
Answer:
 syphilis