10472
CONCLUSION : In Cdks functioning throughout the cell cycle , tyrosine phosphorylation is inhibitory to the activation of kinase , whereas the phosphorylation of threonine in the T - loop is essential for activation .
 Cdks
Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: GENE 
Text: {0} 
Answer:
 Cdks