11690
Phosphoinositide 3-kinase ( PI 3-kinase ) is activated by a diverse set of receptors that determine T-cell function , including the T-cell antigen receptor ( TCR ), the costimulatory receptor CD28 , and negative regulators of T-cell activation such as CTLA-4 .
 CTLA-4, TCR, negative regulators, Phosphoinositide 3-kinase, T-cell antigen receptor, PI 3-kinase, costimulatory receptor CD28
Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: cell line, protein, RNA, DNA, cell type 
Text: {0} 
Answer:
 CTLA-4, TCR, negative regulators, Phosphoinositide 3-kinase, T-cell antigen receptor, PI 3-kinase, costimulatory receptor CD28