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Neuromyelitis optica ( NMO ) is an inflammatory demyelinating disease of the central nervous system caused by binding of pathogenic IgG autoantibodies ( NMO - IgG ) to astrocyte water channel aquaporin - 4 ( AQP4 ) .
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Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: Chemical 
Text: {0} 
Answer:
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