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The majority of pro - inflammatory cytokines initiate signaling cascades that converge at the activation of the Nuclear Factor Kappa B ( NF kappa B ) , a signal transduction molecule that promotes cell survival , proliferation and angiogenesis .
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Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: Chemical 
Text: {0} 
Answer:
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