3475
Heat stability was found to be markedly decreased ( 8 % of residual activity after 20 min of incubation at 46 degrees C ) and a particular characteristic of this enzyme was a biphasic pH curve with a greatly increased activity at low pH .
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Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: Disease 
Text: {0} 
Answer:
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