10253
Rac causes uncapping of actin filaments ( F - actin ) at the plus - ends , through phosphatidylinositol 4 , 5 bisphosphate ( PIP2 ) , and eventually induces membrane ruffling .
 Rac, actin filaments, F - actin
Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: GENE 
Text: {0} 
Answer:
 Rac, actin filaments, F - actin