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A study was undertaken to characterize the mutation ( s ) responsible for Tay - Sachs disease ( TSD ) in a Cajun population in southwest Louisiana and to identify the origins of these mutations .
 Tay - Sachs disease, TSD
Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: Disease 
Text: {0} 
Answer:
 Tay - Sachs disease, TSD