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Based on these observed effects and the well-described role of oxidative stress and inflammation in CKD , especially in type 2 diabetes , it was hypothesized that bardoxolone methyl could improve renal function in CKD patients with type 2 diabetes .
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Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: location, person, organization 
Text: {0} 
Answer:
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