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Among 18 BCR - ABL + leukemias presenting acquired trisomy of chromosome 21 , we report a high frequency ( 33 % ) of recurrent point mutations ( 4 in myeloid blast crisis [ BC ] CML and one in chronic phase CML ) within the DNA - binding region of RUNX1 .
 BCR - ABL + leukemias, chromosome 21, myeloid blast crisis [ BC ] CML, chronic phase CML
Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: Anatomy 
Text: {0} 
Answer:
 BCR - ABL + leukemias, chromosome 21, myeloid blast crisis [ BC ] CML, chronic phase CML