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Similarly , the sequence of the U2 RNA region shown to be involved in pre - mRNA branchpoint recognition in yeast , and exactly conserved in metazoan U2 RNAs , was totally divergent in trypanosomes .
 U2 RNA region, metazoan U2 RNAs
Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: GENE 
Text: {0} 
Answer:
 U2 RNA region, metazoan U2 RNAs