3504
The immunosuppressant sirolimus and curcumin , the main principle of the turmeric spice , have shown antiproliferative effects on many human and not - human cell lines .
 sirolimus, curcumin
Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: Chemical 
Text: {0} 
Answer:
 sirolimus, curcumin