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The development and function of T lymphocytes are regulated tightly by signal transduction pathways that include specific cell-surface receptors , intracellular signaling molecules , and nuclear transcription factors .
 nuclear transcription factors, intracellular signaling molecules, T lymphocytes, cell-surface receptors
Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: cell line, protein, RNA, DNA, cell type 
Text: {0} 
Answer:
 nuclear transcription factors, intracellular signaling molecules, T lymphocytes, cell-surface receptors