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The findings suggest that when SOCS-3 is rapidly induced by IL-2 in T cells , it acts to inhibit IL-2 responses in a classical negative feedback loop .
 IL-2, IL-2, SOCS-3, T cells
Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: cell line, protein, RNA, DNA, cell type 
Text: {0} 
Answer:
 IL-2, IL-2, SOCS-3, T cells