114552
" R7 " is a small-molecule flavonoid and orally active , potent , and selective agonist of the tropomyosin receptor kinase B ( TrkB ) – the main signaling receptor for the neurotrophin brain-derived neurotrophic factor ( BDNF ) – which is under development for the treatment of Alzheimer 's disease .
 Alzheimer 's disease
Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: media, plant, vehicle, astronomical object, time, disease, animal, location, person, organization, mythical figure, food, biology, geographical phenomenon, instrument, event 
Text: {0} 
Answer:
 Alzheimer 's disease