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Overall , this evidence suggests that disparity in estrogen disposition and the subsequent elevation of cumulative body burden of E2 - 3 , 4 - Q may play a role in the development of breast cancer .
 estrogen, E2 - 3 , 4 - Q
Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: Chemical 
Text: {0} 
Answer:
 estrogen, E2 - 3 , 4 - Q