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With longer use amenorrhea ( absence of menstruation ) can occur as can irregular menstruation which is a major source of dissatisfaction , though both can result in improvements with iron deficiency and risk of pelvic inflammatory disease and often do not result in discontinuation of the medication .
 pelvic inflammatory disease
Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: media, plant, vehicle, astronomical object, time, disease, animal, location, person, organization, mythical figure, food, biology, geographical phenomenon, instrument, event 
Text: {0} 
Answer:
 pelvic inflammatory disease