15739
Eleven genes were upregulated in pediatric ALL , including the histone deacetylases HDAC2 and PAK1 , and seven genes were downregulated , including PRMT2 and the putative tumor suppressor EP300 .
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Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: Chemical 
Text: {0} 
Answer:
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