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In areas where there is little iodine in the diet , typically remote inland areas and semi-arid equatorial climates where no marine foods are eaten , iodine deficiency also gives rise to hypothyroidism , the most serious symptoms of which are epidemic goitre ( swelling of the thyroid gland ) , extreme fatigue , mental slowing , depression , weight gain , and low basal body temperatures .
 goitre
Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: media, plant, vehicle, astronomical object, time, disease, animal, location, person, organization, mythical figure, food, biology, geographical phenomenon, instrument, event 
Text: {0} 
Answer:
 goitre