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Our results implicate miR - 22 in downregulating the anti - proliferative p53 and interferon pathways and reveal a new transcription factor - miRNA network that regulates the transition of primary human cells from quiescence to proliferation .
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Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: Chemical 
Text: {0} 
Answer:
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