5147
The role of alterations of the MTS1 tumor suppressor gene on chromosome 9p21 , which encodes p16 , the inhibitor of cyclin-dependent-kinase- 4 and 6 , in tumorigenesis is not yet clear.
 chromosome 9p21, MTS1 tumor suppressor gene, p16, MTS1
Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: cell line, protein, RNA, DNA, cell type 
Text: {0} 
Answer:
 chromosome 9p21, MTS1 tumor suppressor gene, p16, MTS1