6486
We showed that IL-12 had a direct effect on IRF-1 , an effect not mediated indirectly by the induction of IFN-gamma production .
 IRF-1, IFN-gamma, IL-12
Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: cell line, protein, RNA, DNA, cell type 
Text: {0} 
Answer:
 IRF-1, IFN-gamma, IL-12