13180
In this small library of novel bioactive macrocyclic lathyrane diterpene derivatives , designed to evaluate structure - activity relationships essential in overcoming multidrug resistance ( MDR ) , some correlations between MDR reversal and molecular weight , accessible solvent areas , and octanol / water partition coefficient were identified that can contribute to the development of new selective P - gp reversal agents .
 lathyrane diterpene, octanol
Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: Chemical 
Text: {0} 
Answer:
 lathyrane diterpene, octanol