12452
It has been proposed that insulin resistance ( IR ) underlies a cluster of cardiovascular disease ( CVD ) risk factors constituting a " metabolic syndrome . " CVD is a leading cause of premature mortality among indigenous Australians .
 insulin
Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: GENE 
Text: {0} 
Answer:
 insulin