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Glucose 6 - phosphate dehydrogenase ( G6PD ) is a cytosolic enzyme encoded by a housekeeping X - linked gene whose main function is to produce NADPH , a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions .
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Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: Disease 
Text: {0} 
Answer:
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