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Knockdown of PIP5K1B in control fibroblasts using shRNA reproduced abnormal actin cytoskeleton remodeling , whereas over - expression of PIP5K1B , but not FXN , suppressed this phenotype in FRDA cells .
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Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: Chemical 
Text: {0} 
Answer:
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