9175
Ligand binding to the receptor complex leads to tyrosine phosphorylation and activation of Janus kinases ( Jak ) , phosphorylation of the signal transducing subunit gp130 , followed by recruitment and phosphorylation of the signal transducer and activator of transcription factors STAT3 and STAT1 and the src homology domain ( SH2 ) - containing protein tyrosine phosphatase ( SHP2 ) .
 Janus kinases, Jak, signal transducing subunit gp130, signal transducer and activator of transcription factors, STAT3, STAT1, src homology domain, SH2, protein tyrosine phosphatase, SHP2
Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: GENE 
Text: {0} 
Answer:
 Janus kinases, Jak, signal transducing subunit gp130, signal transducer and activator of transcription factors, STAT3, STAT1, src homology domain, SH2, protein tyrosine phosphatase, SHP2