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In a Turkish family with the diagnosis of Li - Fraumeni syndrome , we analyzed the mutation pattern of TP53 , P57KIP2 , P15INK4B , and P16INK4A in the peripheral blood , and loss of heterozygosity ( homo / hemizygous deletion ) pattern of TP53 and P15INK4B / P16INK4A in two tumor tissues .
 Li - Fraumeni syndrome, tumor
Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: Disease 
Text: {0} 
Answer:
 Li - Fraumeni syndrome, tumor