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Human Duo contains a guanine nucleotide exchange factor ( GEF ) domain that is likely to be rac1 - specific , a pleckstrin homology ( PH ) domain and spectrin - like repeat units .
 Human Duo, guanine nucleotide exchange factor, GEF, rac1, pleckstrin homology, PH, spectrin - like repeat units
Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: GENE 
Text: {0} 
Answer:
 Human Duo, guanine nucleotide exchange factor, GEF, rac1, pleckstrin homology, PH, spectrin - like repeat units