99473
When the blood contains inadequate amounts of A1AT or functionally defective A1AT ( such as in alpha-1 antitrypsin deficiency ) , neutrophil elastase is excessively free to break down elastin , degrading the elasticity of the lungs , which results in respiratory complications , such as chronic obstructive pulmonary disease , in adults .
 alpha-1 antitrypsin deficiency
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Answer:
 alpha-1 antitrypsin deficiency