8185
Cloning of a human phosphoinositide 3 - kinase with a C2 domain that displays reduced sensitivity to the inhibitor wortmannin .
 human phosphoinositide 3 - kinase, C2
Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: GENE 
Text: {0} 
Answer:
 human phosphoinositide 3 - kinase, C2