8534
When tested with wild - type ( DBA / 2 ) p16 , both A134C and G232A BALB / c - specific variants of p16 were inefficient in their ability to inhibit the activity of cyclin D2 / CDK4 in kinase assays with retinoblastoma protein , suggesting this defective , inherited allele plays an important role in the genetic susceptibility of BALB / c mice for plasmacytoma induction and that p16 ( INK4a ) is a strong candidate for the Pctr1 locus .
 p16, p16, cyclin D2, CDK4, retinoblastoma protein, p16, INK4a, Pctr1 locus
Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: GENE 
Text: {0} 
Answer:
 p16, p16, cyclin D2, CDK4, retinoblastoma protein, p16, INK4a, Pctr1 locus