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The pooled statistical analysis for ventricular septal ( VSD ) and midline ( MD ) defects was performed for rat fetuses exposed to piroxicam , selective and non - selective COX - 2 inhibitor based on present and historic data .
 ventricular septal ( VSD ) and midline ( MD ) defects, piroxicam
Please list all entity words in the text that fit the category. Output format is "word1, word2". 
Option: Disease, Chemical 
Text: {0} 
Answer:
 ventricular septal ( VSD ) and midline ( MD ) defects, piroxicam