13298
We reported 3 patients who developed acute generalized dystonia and akinetic rigid syndrome following an initial therapy with d - penicillamine 125 - 500 mg daily .
 adverse effect: acute generalized dystonia, d - penicillamine; adverse effect: akinetic rigid syndrome, d - penicillamine
Given a phrase that describes the relationship between two words, extract the words and the lexical relationship between them. The output format should be "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 adverse effect: acute generalized dystonia, d - penicillamine; adverse effect: akinetic rigid syndrome, d - penicillamine