1621
Beginning ductopenia was present in two , suggesting that itraconazole might be responsible for the occurrence of prolonged drug - induced cholangiopathy .
 adverse effect: cholangiopathy, itraconazole; adverse effect: ductopenia, itraconazole
Given a phrase that describes the relationship between two words, extract the words and the lexical relationship between them. The output format should be "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 adverse effect: cholangiopathy, itraconazole; adverse effect: ductopenia, itraconazole