4162
We present two cases of nitrofurantoin - induced pulmonary toxicity in which the initial HRCT showed a widespread reticular pattern and associated distortion of the lung parenchyma , thought to represent established fibrosis .
 adverse effect: distortion of the lung parenchyma, nitrofurantoin; adverse effect: fibrosis, nitrofurantoin; adverse effect: pulmonary toxicity, nitrofurantoin; adverse effect: widespread reticular pattern, nitrofurantoin
Given a phrase that describes the relationship between two words, extract the words and the lexical relationship between them. The output format should be "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 adverse effect: distortion of the lung parenchyma, nitrofurantoin; adverse effect: fibrosis, nitrofurantoin; adverse effect: pulmonary toxicity, nitrofurantoin; adverse effect: widespread reticular pattern, nitrofurantoin