7663
Animals treated with HAL showed a highly significant 32%-46 % loss of tyrosine hydroxylase ( TH ) immunoreactive neurons in the substantia nigra , and 20 % contraction of the TH stained dendritic arbour .
 adverse effect: significant 32%-46 % loss of tyrosine hydroxylase ( TH ) immunoreactive neurons, HAL
Given a phrase that describes the relationship between two words, extract the words and the lexical relationship between them. The output format should be "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 adverse effect: significant 32%-46 % loss of tyrosine hydroxylase ( TH ) immunoreactive neurons, HAL