1425
Careful follow - up of so - called " self - limited " insulin edema is encouraged , and the early institution of diuretic therapy is advocated in elderly patients to prevent the development of overt cardiac failure .
 adverse effect: edema, insulin
Given a phrase that describes the relationship between two words, extract the words and the lexical relationship between them. The output format should be "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 adverse effect: edema, insulin