12762
Contrary to previous recommendations , our experience cautions against the further use of high - dose cytarabine in patients who develop PPE , and is a timely reminder of the potential toxicity of this agent , which is now increasingly being used as first - line treatment in the management of haematologic malignancies .
 adverse effect: PPE, cytarabine
Given a phrase that describes the relationship between two words, extract the words and the lexical relationship between them. The output format should be "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 adverse effect: PPE, cytarabine