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 Mark W. Parrino , the president of the American Association for the Treatment of Opioid Dependence , a national methadone advocacy group based in Manhattan , said that this kind of cross-addiction among methadone users is a growing problem in the roughly 125 clinics in the New York area , but that it only afflicts an estimated 15 percent of methadone users . 
 location contains: New York, Manhattan
Given a phrase that describes the relationship between two words, extract the words and the lexical relationship between them. The output format should be "relation1: word1, word2; relation2: word3, word4". 
Option: nationality, country capital, place of death, children, location contains, place of birth, place lived, administrative division of country, country of administrative divisions, company, neighborhood of, company founders 
Text: {0} 
Answer:
 location contains: New York, Manhattan