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The authors suggest that risperidone may increase affect in patients with schizophrenia and that some patients , especially those with anxiety , may have difficulty managing the increase .
 adverse effect: increase affect, risperidone
Given a phrase that describes the relationship between two words, extract the words and the lexical relationship between them. The output format should be "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 adverse effect: increase affect, risperidone