1944
We hypothesize that caffeine toxicity injured the muscle cells , which were fragile due to the potassium depletion induced by the coexisting hyponatremia , to result in unusually severe rhabdomyolysis .
 adverse effect: caffeine toxicity, caffeine; adverse effect: coexisting hyponatremia, caffeine; adverse effect: injured the muscle cells, caffeine; adverse effect: potassium depletion, caffeine; adverse effect: rhabdomyolysis, caffeine
Given a phrase that describes the relationship between two words, extract the words and the lexical relationship between them. The output format should be "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 adverse effect: caffeine toxicity, caffeine; adverse effect: coexisting hyponatremia, caffeine; adverse effect: injured the muscle cells, caffeine; adverse effect: potassium depletion, caffeine; adverse effect: rhabdomyolysis, caffeine