2311
RESULTS : The estimated number of Accutane prescriptions for reproductive - aged women has more than doubled in the past 10 years ; it is the most widely used teratogenic drug in the United States , with approximately 2.5 per 1,000 reproductive - aged women exposed to Accutane in 1999 .
 adverse effect: teratogenic, Accutane
Given a phrase that describes the relationship between two words, extract the words and the lexical relationship between them. The output format should be "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 adverse effect: teratogenic, Accutane