10649
Rofecoxib , used for dysmenorrhea , caused a herpetiform fixed drug eruption predominantly involving the lips with classic clinical and histological findings in a red - brown lesion on the dorsal hand .
 adverse effect: herpetiform fixed drug eruption, Rofecoxib; adverse effect: red - brown lesion, Rofecoxib
Given a phrase that describes the relationship between two words, extract the words and the lexical relationship between them. The output format should be "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 adverse effect: herpetiform fixed drug eruption, Rofecoxib; adverse effect: red - brown lesion, Rofecoxib