4127
These observations indicate that submassive hepatic necrosis may result from treatment with propylthiouracil and are consistent with the notion that sensitization mechanisms may be responsible for the hepatic injury induced by this drug .
 adverse effect: hepatic injury, propylthiouracil; adverse effect: submassive hepatic necrosis, propylthiouracil
Given a phrase that describes the relationship between two words, extract the words and the lexical relationship between them. The output format should be "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 adverse effect: hepatic injury, propylthiouracil; adverse effect: submassive hepatic necrosis, propylthiouracil