1592
The use of methotrexate ( MTX ) has been contraindicated for treatment of severe psoriasis in HIV infection on the basis of six previously reported cases in which MTX appeared to potentiate opportunistic infections and accelerate HIV disease .
 adverse effect: accelerate HIV disease, methotrexate; adverse effect: accelerate HIV disease, MTX; adverse effect: accelerate HIV disease, MTX
Given a phrase that describes the relationship between two words, extract the words and the lexical relationship between them. The output format should be "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 adverse effect: accelerate HIV disease, methotrexate; adverse effect: accelerate HIV disease, MTX; adverse effect: accelerate HIV disease, MTX