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Coadministration of antidepressant agents such as nefazodone , or any other drug that inhibits the CYP3A4 isoenzyme subfamily , should be anticipated to interfere with tacrolimus metabolism .
 adverse effect: interfere with tacrolimus metabolism, nefazodone; adverse effect: interfere with tacrolimus metabolism, tacrolimus
Given a phrase that describes the relationship between two words, extract the words and the lexical relationship between them. The output format should be "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 adverse effect: interfere with tacrolimus metabolism, nefazodone; adverse effect: interfere with tacrolimus metabolism, tacrolimus