1445
Two cases of lepromatous leprosy with erythema nodosum leprosum who were on high doses of clofazimine , showed discoloration of nail plate , subungual hyperkeratosis and onycholysis .
 adverse effect: discoloration of nail plate, clofazimine; adverse effect: onycholysis, clofazimine; adverse effect: subungual hyperkeratosis, clofazimine
Given a phrase that describes the relationship between two words, extract the words and the lexical relationship between them. The output format should be "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 adverse effect: discoloration of nail plate, clofazimine; adverse effect: onycholysis, clofazimine; adverse effect: subungual hyperkeratosis, clofazimine