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The reported cases of in utero exposure to cyclosposphamide shared the following manifestations with our patient : growth deficiency , developmental delay , craniosynostosis , blepharophimosis , flat nasal bridge , abnormal ears , and distal limb defects including hypoplastic thumbs and oligodactyly .
 adverse effect: blepharophimosis, cyclosposphamide; adverse effect: craniosynostosis, cyclosposphamide; adverse effect: developmental delay, cyclosposphamide; adverse effect: distal limb defects, cyclosposphamide; adverse effect: flat nasal bridge, cyclosposphamide; adverse effect: hypoplastic thumbs, cyclosposphamide; adverse effect: oligodactyly, cyclosposphamide
Given a phrase that describes the relationship between two words, extract the words and the lexical relationship between them. The output format should be "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 adverse effect: blepharophimosis, cyclosposphamide; adverse effect: craniosynostosis, cyclosposphamide; adverse effect: developmental delay, cyclosposphamide; adverse effect: distal limb defects, cyclosposphamide; adverse effect: flat nasal bridge, cyclosposphamide; adverse effect: hypoplastic thumbs, cyclosposphamide; adverse effect: oligodactyly, cyclosposphamide