4124
After therapy with parenteral amiodarone ( 2300 mg in 3 days ) and other measures , signs of congestive heart failure disappeared ; subsequently the patient developed jaundice , marked increase in serum transaminase levels and fall in prothrombin time , and histologic changes of severe centrilobular necrosis were observed in hepatic biopsy .
 adverse effect: fall in prothrombin time, amiodarone; adverse effect: jaundice, amiodarone; adverse effect: marked increase in serum transaminase levels, amiodarone; adverse effect: severe centrilobular necrosis, amiodarone
Given a phrase that describes the relationship between two words, extract the words and the lexical relationship between them. The output format should be "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 adverse effect: fall in prothrombin time, amiodarone; adverse effect: jaundice, amiodarone; adverse effect: marked increase in serum transaminase levels, amiodarone; adverse effect: severe centrilobular necrosis, amiodarone