3662
Grade 3 hepatotoxicity ( AST and ALT > 5 to 20 upper limit normal ) or higher has been observed in as many as 1.4 % of MS patients on IFN beta .
 adverse effect: Grade 3 hepatotoxicity, IFN beta
Given a phrase that describes the relationship between two words, extract the words and the lexical relationship between them. The output format should be "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 adverse effect: Grade 3 hepatotoxicity, IFN beta