1900
OBJECTIVE : To describe a case of exacerbated mania potentially related to an interaction between lopinavir / ritonavir and valproic acid ( VPA ) and propose a mechanism of action for this interaction .
 adverse effect: mania, lopinavir; adverse effect: mania, ritonavir; adverse effect: mania, valproic acid; adverse effect: mania, VPA
Given a phrase that describes the relationship between two words, extract the words and the lexical relationship between them. The output format should be "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 adverse effect: mania, lopinavir; adverse effect: mania, ritonavir; adverse effect: mania, valproic acid; adverse effect: mania, VPA