12979
When the acute manic state is characterized by marked psychotic symptoms and intense anxiety , it may be associated with increased vulnerability to the development of severe lithium neurotoxicity .
 adverse effect: intense anxiety, lithium; adverse effect: neurotoxicity, lithium; adverse effect: psychotic symptoms, lithium
Given a phrase that describes the relationship between two words, extract the words and the lexical relationship between them. The output format should be "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 adverse effect: intense anxiety, lithium; adverse effect: neurotoxicity, lithium; adverse effect: psychotic symptoms, lithium