3015
In a phase II study of hycanthone in patients with breast cancer we have recently observed severe hepatotoxicity , even at lower doses , which resulted in two drug - related deaths .
 adverse effect: severe hepatotoxicity, hycanthone
Given a phrase that describes the relationship between two words, extract the words and the lexical relationship between them. The output format should be "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 adverse effect: severe hepatotoxicity, hycanthone