99
From these data , acute generalized dystonia with brainstem and thalamic lesions may occur in WD patients after an initial d - penicillamine therapy .
 adverse effect: acute generalized dystonia, d - penicillamine; adverse effect: brainstem and thalamic lesions, d - penicillamine
Given a phrase that describes the relationship between two words, extract the words and the lexical relationship between them. The output format should be "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 adverse effect: acute generalized dystonia, d - penicillamine; adverse effect: brainstem and thalamic lesions, d - penicillamine