3664
Ethambutol is frequently used in the treatment of tuberculosis , and , although optic neuropathies have been reported with the use of ethambutol , this adverse side effect has been considered to be rare and generally reversible with discontinuation of the medication .
 adverse effect: optic neuropathies, Ethambutol
Given a phrase that describes the relationship between two words, extract the words and the lexical relationship between them. The output format should be "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 adverse effect: optic neuropathies, Ethambutol