10760
The pathophysiological mechanisms remain unknown , although the drug could act through massive cytokines liberation after destruction of CD20 positive cells by rituximab .
 adverse effect: destruction of CD20 positive cells, rituximab; adverse effect: massive cytokines liberation, rituximab
Given a phrase that describes the relationship between two words, extract the words and the lexical relationship between them. The output format should be "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 adverse effect: destruction of CD20 positive cells, rituximab; adverse effect: massive cytokines liberation, rituximab