12850
We describe a patient with CREST syndrome ( calcinosis , Raynaud 's phenomenon , esophageal dysfunction , sclerodactyly , and telangiectasia ) who paradoxically experienced worsening of Raynaud 's phenomenon when using yohimbine for ED .
 adverse effect: worsening of Raynaud 's phenomenon, yohimbine
Given a phrase that describes the relationship between two words, extract the words and the lexical relationship between them. The output format should be "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 adverse effect: worsening of Raynaud 's phenomenon, yohimbine