6639
We describe 2 male patients , a 49-year - old with psoriatic arthritis and impaired renal function and a 43-year - old renal transplant recipient , who both sustained a marked decline in glomerular filtration rate in conjunction with a selective inhibitor of cyclooxygenase-2 ( COX-2 ) , rofecoxib .
 adverse effect: decline in glomerular filtration rate, rofecoxib
Given a phrase that describes the relationship between two words, extract the words and the lexical relationship between them. The output format should be "relation1: word1, word2; relation2: word3, word4". 
Option: adverse effect 
Text: {0} 
Answer:
 adverse effect: decline in glomerular filtration rate, rofecoxib