From Hell is a 2001 American Czech period horror thriller movie directed by The Hughes Brothers and was based on the graphic novel of the same name by Alan Moore and Eddie Campbell. It stars Johnny Depp, Heather Graham, Ian Holm, Ian Richardson, Robbie Coltrane, Jason Flemyng, Annabelle Apsion, Lesley Sharp, Susan Lynch, Paul Rhys, Ian McNeice, David Schofield, Bruce Byron and was distributed by 20th Century Fox.