In October 1st, 2016, he was nominated to the elections to the Ecuadorian presidency by his party, Alianza País. In February 2017, Moreno and Guillermo Lasso made it to the run-off election which was held on April 2, 2017. Moreno won the election with 51% of the vote to Lasso's 49%. Moreno was then sworn-in as President of Ecuador on 24 May 2017 in Quito.