Issawi Frej (, ; born 14 December 1963) is an Arab-Israeli politician who currently serves as a minister and was a member of the Knesset for Meretz in 2021. He was also a member of Knesset for the party between 2013 and 2019. He is the Minister of Regional Cooperation since 2021. He is the second Muslim minister in Israeli history, after Raleb Majadle.