I have already said the Indians gave the white men little trouble in that section during the pioneer days. In that respect, no comparison can be made with Kentucky and Ohio. As early as 1720, the lead deposits in Missouri attracted notice, and its oldest town, Saint Genevieve, was founded in 1755. St. Louis became the depot for the fur trade of the vast region beyond, and at the breaking out of the Revolution, was a town of considerable importance.