And that misuse of the aerosol sprays is probably responsible for about three thousand five hundred deaths, but I think you've got to put that into perspective, first of all against the six thousand people who are killed on the roads every year in Britain, and you've also got to set it against our estimate that there are more than a quarter of a million people alive today who would have died in childhood if it hadn't been specifically for the advantage of being able to take medicines, anti-biotics generally in their childhood to keep them alive.