Lieke Klaassen (born 23 April 1991) is a Dutch water polo player. She was a member of the Netherlands women's national water polo team. She played at the 2011 World Aquatics Championships, 2013 World Aquatics Championships, 2015 World Aquatics Championships, 2012 Women's European Water Polo Championship, 2014 Women's European Water Polo Championship, 2016 Women's European Water Polo Championship, and 2017 FINA Women's Water Polo World League.