Mahomes was born on September 17, 1995, in Tyler, Texas, to MLB player, Pat Mahomes and Randi Mahomes. In high school, Mahomes played football, baseball, and basketball. Playing football in his senior year, Mahomes he had 4,619 passing yards and 50 passing touchdowns. In baseball, he threw a no-hitter with 16 strikeouts in a game. He was selected in the 37th round of the 2014 MLB Draft by the Detroit Tigers, but did not sign a contract.