On 19 March 2014, it was announced that the popular BBC long-running continuous drama "EastEnders," had cast Hammond in the role of disabled market trader Donna Yates. The character of Donna was not originally going to be written into "EastEnders" as a disabled character, but Hammond impressed bosses at her audition, and was awarded the part. Donna is the second disabled regular in the soap, after Adam Best (David Proud) who left the show in 2010. Speaking of her casting, Hammond said: "I'm really excited to join the cast of "EastEnders". It's a great opportunity to be a part of such a big and popular show. Donna is a bit of a handful but they're always the most fun characters to play! It feels good to be bad!" Donna's storylines have included: her fierce attitude, which often runs her into arguments; the introduction of her family; and a relationship with Fatboy (Ricky Norwood). Lisa decided to leave the soap in 2018 to pursue other roles. Her last appearance in "EastEnders" was on 20 July 2018, when Donna was seen leaving in the back of a black cab.