Luigi De Magistris (23 February 1926 – 16 February 2022) was a Sardinian prelate of the Catholic Church. He was Pro-Major Penitentiary of the Apostolic Penitentiary from 2001 to 2003 after working for more than forty years in the Roman Curia. He was made a bishop in 1996, an archbishop in 2001, and a cardinal in 2015. He was born in Cagliari, Sardinia, Italy.