1881 Dr John H Watson having received a medical degree is attached to the British army war in Afghanistan; however after being badly wounded and stricken with fever, he is sent back to England with a half-pay pension for a year. Finding that he must move to cheaper lodgings, he makes the acquaintance of Sherlock Holmes -an eccentric student of chemistry and crime; this however is a sideline-Holmes real profession is that of a private consulting detective-with an extraordinary memory for both observation and knowledge Holmes can deduce both a persons profession and where they have been. Detective Gregson of Scotland Yard letters Holmes to consult him on a murder case. Holmes and Watson go to the scene of the crime-Holmes deduces that the victim Enoch Drebber had been poisoned; that the murderer smoke cigars; was over six feet tall and had a florid complexion, and that the cause of the murder was a woman. Despite a false start, Holmes tries to trap the killer with a fake ring advertisement but fails. The second murder is of secretary Joseph Strangerson who was stabbed in his hotel room. One clue is a small pillbox containing two pills-one harmless and one a poison. Holmes has a cabman try to lift his trunk-and arrests the cabman Jefferson Hope by name as the killer. Taken to Scotland Yard, Hope- who is dying from a weak heart- confesses: over twenty years before he was engaged to marry the daughter of a wealthy farmer in Salt Lake City Utah; however Strangerson killed the father and Drebber forced the girl to marry him; she died within a month of a broken heart; Hope vowed revenge and after many years traced Drebber and Strangerson to Cleveland Ohio; the now wealthy Drebber had Hope imprisoned; when Hope was released he found that Drebber and Strangerson fled to Europe-; St Petersburg Russia; Cobenhagen Denmark; Paris, France and then to London. Hope got himself hired as a Cabman so he could spy out his query. Drebber and Stragerson split up; the drunken Drebber gets himself thrown out of his boarding house for trying to court the landlady's daughter. Hope takes Drebber in his cab to the murder scene and confronts Drebber with his real identity. He then forces Drebber to take a pill while he eats the second one. Drebber dies looking at his wives wedding ring; Hope then goes after Strangerson and offers him the same choice-Starangerson tries to strangle Hope who stabs him. Hope decides to earn a little more money to go back to America even though he admits he has nothing left to live for having accomplished his revenge, when he hears a Baker Street Irregeler [a gang of boy spies employed by Holmes] inquire for him by name for a cab job. That very night Hopes heart bursts in his cell; after Holmes and Watson read about it in the newspaper Watson begins to write for the public an 18-year career of Holmes consulting work.