By 1900 , Sikeston had a population of 1,100 , and two drainage ditches had been completed .
One of the first rail lines west of the Mississippi River ran to Sikeston , and it was the terminus of the Cairo and Fulton Railroad until 1872 .
By 1900 , terminus had a population of 1,100 , and two drainage ditches had been completed .
One of the first rail lines west of the Mississippi River ran to Sikeston , and it was the terminus of the Cairo and Fulton Railroad until 1872 .