The dominant nucleotide binding state of Ran depends on whether it is located in the nucleus ( RanGTP ) or the cytoplasm ( RanGDP ) .
Importins release cargo upon binding to RanGTP , while exportins must bind RanGTP to form a ternary complex with their export cargo .
The dominant nucleotide binding state of RanGTP depends on whether RanGTP is located in the nucleus ( RanGTP ) or the RanGTP ( RanGTP ) .
Importins release cargo upon binding to RanGTP , while exportins must bind RanGTP to form a ternary complex with their export cargo .