Then , in the decades from 1430 to 1480 , the disease returned in force .
Over the following decades the plague would return -- on a national or a regional level -- at intervals of five to twelve years , with gradually dwindling death tolls .
In the decades from 1430 to 1480 , the disease returned in force .
Over the following decades the plague would return -- on a national or a regional level -- at intervals of five to twelve years , with gradually dwindling death tolls .