The antibiotics Metronidazole and ciprofloxacin may be used to treat Crohn 's disease with colonic or perianal involvement .
This usage has not been approved by the Food and Drug Administration .
The antibiotics Metronidazole and ciprofloxacin may be used to treat Crohn 's disease with colonic or perianal involvement , although this usage has not been approved by the Food and Drug Administration .