This approach has also been used to generate knockin rats by TALEN mRNA microinjection in one - cell embryos .
Wu et al. obtained a Sp110 knockin cattle using Talen nickases to induce increased resistance of tuberculosis .
This approach has also been used to generate knockin rats by Talen   microinjection in one - cell embryos .
Wu et al. obtained a Sp110 knockin cattle using Talen nickases to induce increased resistance of tuberculosis .