Finally , in order to achieve tracking quality , the values are in most commercial applications smoothed by a spline smoothing function along the ROI .
The regional measurements are not pure regional , but rather to a degree , spline functions of the global average .
Finally , in order to achieve tracking quality , the values are in most commercial applications smoothed by a spline smoothing function along the ROI , so the regional measurements are not pure regional , but rather to a degree , spline functions of the global average .