Some LTag homologs also have a disordered C - terminal tail called the host range domain although the molecular mechanism of its essentiality is unclear .
The host range domain can be phosphorylated and in some strains is essential .
Some LTag homologs also have a disordered C - terminal tail called the host range domain , which can be phosphorylated and in some strains is essential , although the molecular mechanism of its essentiality is unclear .