CYP3A4 is mostly responsible for biotransformation of etoricoxib to carboxylic acid metabolite .
A non CYP450 metabolism pathway to glucuronide metabolite is also at hand .
CYP3A4 is mostly responsible for biotransformation of etoricoxib to carboxylic acid metabolite , but a non CYP450 metabolism pathway to glucuronide metabolite is also at hand .