It is followed by karyorrhexis , or fragmentation of the nucleus .
Pyknosis , or karyopyknosis , is the irreversible condensation of chromatin in the nucleus of a cell undergoing necrosis or apoptosis .
Pyknosis is followed by karyorrhexis , or fragmentation of the nucleus .
Pyknosis , or karyopyknosis , is the irreversible condensation of chromatin in the nucleus of a cell undergoing necrosis or apoptosis .