Flot - 2 binds to PAR - 1 and may influence tumour progression .
PAR - 1 is a known upstream mediator of major signal transduction pathways implicated in cell growth and metastasis .
Flot - 2 binds to PAR - 1 , a known upstream mediator of major signal transduction pathways implicated in cell growth and metastasis , and may influence tumour progression .