However , it has been associated with progressive multifocal leukoencephalopathy , a usually fatal viral infection of the brain , that may limit its use .
Natalizumab is an anti-integrin monoclonal antibody that shown utility as induction and maintenance treatment for moderate to severe Crohn 's disease .
Natalizumab has been associated with progressive multifocal leukoencephalopathy , a usually fatal viral infection of the brain , that may limit Natalizumab 's use .
Natalizumab is an anti-integrin monoclonal antibody that shown utility as induction and maintenance treatment for moderate to severe Crohn 's disease .