Second , reads from non-jumped fragments ( i.e. fragments without the circularization junction ) are sequenced and reduce genomic coverage .
First , a read can pass through the biotinylated circularization junction and reduce the effective read length .
Reads from non-jumped fragments ( i.e. fragments without the circularization junction ) are sequenced and reduce genomic coverage .
First , a read can pass through the biotinylated circularization junction and reduce the effective read length .