Clinical laboratories do culture and isolate them , but a negative result does not rule out infection , because it may be due simply to reluctance to grow in vitro .
Like various other anaerobes , Actinomyces species are fastidious and thus not easy to culture and isolate .
Clinical laboratories do culture and isolate species , but a negative result does not rule out infection , because it may be due simply to reluctance to grow in vitro .
Like various other anaerobes , Actinomyces species are fastidious and thus not easy to culture and isolate .