Histone acetylation and the cAMP - PKA - CREB1 pathway are extremely important for normal hippocampal function and aging in mice .
Scientists further investigate RbAp48 to test whether its modulation was the cause of age - related memory losses in animals , especially mice .
Since histone acetylation and the cAMP - PKA - CREB1 pathway are extremely important for normal hippocampal function and aging in mice , scientists further investigate RbAp48 to test whether its modulation was the cause of age - related memory losses in animals , especially mice .