In contrast , the dimeric form is its structure in T - state conformation , namely with a low binding affinity to PEP .
The tetrameric form is the pyruvate kinase structure in its R - state conformation , namely with high binding affinity to PEP .
The dimeric form is its structure in T - state conformation , namely with a low binding affinity to PEP .
The tetrameric form is the pyruvate kinase structure in its R - state conformation , namely with high binding affinity to PEP .