Furthermore , glucose was found to inhibit and disrupt gluconeogenesis , leaving pyruvate kinase activity and glycolysis unaffected .
Alternatively , insulin interferes with the effect of glucagon , cyclic AMP and epinephrine , causing pyruvate kinase to function normally and gluconeogenesis to be shut down .
Glucose was found to inhibit and disrupt gluconeogenesis , leaving pyruvate kinase activity and glycolysis unaffected .
Alternatively , insulin interferes with the effect of glucagon , cyclic AMP and epinephrine , causing pyruvate kinase to function normally and gluconeogenesis to be shut down .