A polymorphism of the enzyme CYP2C19 affects the response to clopidogrel hence decreasing enzymatic activity and therefore reducing the active metabolite of clopidogrel .
One of the crucial enzymes in clopidogrel metabolism is CYP2C19 which is involved in both steps of the biotransformation .
A polymorphism of the CYP2C19 CYP2C19 affects the response to clopidogrel hence decreasing enzymatic activity and therefore reducing the active metabolite of clopidogrel .
One of the crucial enzymes in clopidogrel metabolism is CYP2C19 which is involved in both steps of the biotransformation .