The first major leaguer whose number was retired was Gehrig , in July 1939 , following his retirement due to amyotrophic lateral sclerosis , which became known popularly as Lou Gehrig 's Disease .
Hence , Babe Ruth wore number 3 and Lou Gehrig number 4 .
The first major leaguer whose number was retired was Lou Gehrig , in July 1939 , following his retirement due to amyotrophic lateral sclerosis , which became known popularly as Lou Gehrig 's Disease .
Hence , Babe Ruth wore number 3 and Lou Gehrig number 4 .