The J domain interacts with Hsc70 heat - shock proteins .
The J domain is a DnaJ molecular chaperone that is required for viral genome replication in vivo ( but is dispensable in cell - free laboratory experiments ) .
The J chaperone interacts with Hsc70 heat - shock proteins .
The J domain is a DnaJ molecular chaperone that is required for viral genome replication in vivo ( but is dispensable in cell - free laboratory experiments ) .