This sequence is notable as one of the earliest to feature 1 - methoxy - 3 - siloxybutadiene in total synthesis .
1 - methoxy - 3 - siloxybutadiene is the so - called Danishefsky diene .
This sequence is notable as one of the earliest to feature 1 - methoxy - 3 - siloxybutadiene , the so - called Danishefsky diene , in total synthesis .