Consequently , the increase in pyruvate kinase activity directs metabolic flux through glycolysis rather than gluconeogenesis .
Due to the allosteric inhibitory effects of ATP on pyruvate kinase , a decrease in ATP results in diminished inhibition and the subsequent stimulation of pyruvate kinase .
The increase in pyruvate kinase activity directs metabolic flux through glycolysis rather than gluconeogenesis .
Due to the allosteric inhibitory effects of ATP on pyruvate kinase , a decrease in ATP results in diminished inhibition and the subsequent stimulation of pyruvate kinase .