During embryonic development in mice , inactivation of LPP3 results in early lethality in part due to failure of extra-embryonic vascular development .
It was further observed that reduced levels of endothelial LPP3 is associated with disturbed flow and mechano - regulation in blood vessels .
During embryonic development in mice , inactivation of endothelial results in early lethality in part due to failure of extra-embryonic vascular development .
It was further observed that reduced levels of endothelial LPP3 is associated with disturbed flow and mechano - regulation in blood vessels .