These compounds are activated in the cells by being converted into nucleotides ; they are administered as nucleosides as charged nucleotides can not easily cross cell membranes .
The viral polymerase incorporates these compounds with non-canonical bases .
These compounds are activated in the cells by being converted into nucleotides ; compounds are administered as nucleosides as charged nucleotides can not easily cross cell membranes .
The viral polymerase incorporates these compounds with non-canonical bases .