It enters from Missouri across the Mississippi River on the Mark Twain Memorial Bridge , and runs east , crossing Interstate 55 in Springfield .
In the state of Illinois , U.S. 36 runs concurrently with much of Interstate 72 .
U.S. enters from Missouri across the Mississippi River on the Mark Twain Memorial Bridge , and runs east , crossing Interstate 55 in Springfield .
In the state of Illinois , U.S. 36 runs concurrently with much of Interstate 72 .