Structurally , HtrA2 is a trimeric molecule with central protease domains and a carboxy - terminal PDZ domain , which is characteristic of the HtrA family .
HtrA2 shows similarities with DegS , a bacterial protease present in the periplasm of gram - negative bacteria .
Structurally , HtrA2 is a trimeric HtrA2 with central protease domains and a carboxy - terminal PDZ domain , which is characteristic of the HtrA2 family .
HtrA2 shows similarities with DegS , a bacterial protease present in the periplasm of gram - negative bacteria .