Brandon Radcliff rushed for 118 yards and a score as Louisville won its biggest ACC before national TV audience .
Jaire Alexander contributed a 69 - yard punt return for a TD and a fumble recovery leading to another Louisville score .
Brandon Radcliff rushed for 118 yards and a score as Louisville won Louisville 's biggest ACC before national TV audience .
Jaire Alexander contributed a 69 - yard punt return for a TD and a fumble recovery leading to another Louisville score .