Next , the first macromolecules capable of replication were formed , probably through spontaneous base pairing .
First , there must have been the formation of nucleotides and amino acids from simple carbon compounds and non-biological catalysts .
The first macromolecules capable of replication were formed , probably through spontaneous base pairing .
First , there must have been the formation of nucleotides and amino acids from simple carbon compounds and non-biological catalysts .