Free flaps are usually the best solution for reconstruction of large defects that can not be closed locally .
That have unfavourable wound conditions such as severe infection , exposed sinuses , dura or brain tissue , CSF leakage or radiation damage .
Free flaps are usually the best solution for reconstruction of large defects that can not be closed locally and that have unfavourable wound conditions such as severe infection , exposed sinuses , dura or brain tissue , CSF leakage or radiation damage .