Rather , FXR induces expression of small heterodimer partner ( SHP ) , which then functions to inhibit transcription of the CYP7A1 gene .
FXR does not directly bind to the CYP7A1 promoter .
FXR induces expression of small heterodimer partner ( SHP ) , which then functions to inhibit transcription of the CYP7A1 gene .
FXR does not directly bind to the CYP7A1 promoter .