I - 22 begins at an interchange with I - 269 at Byhalia in northmost Mississippi .
I - 22 continues across rural areas , connecting together towns such as Fulton , Tupelo , New Albany , and Holly Springs .
I - 22 begins at an interchange with I - 269 at Byhalia in northmost Mississippi and continues across rural areas , connecting together towns such as Fulton , Tupelo , New Albany , and Holly Springs .