Similarly , BDNF exon IV expression following depolarization is increased and is associated with increased histone acetylation , reduced DNA methylation and reduced MeCP2 binding at the BDNF promoter .
In concordance , histone acetylation , particularly at the BDNF promoter II , increases BDNF expression .
BDNF exon IV expression following depolarization is increased and is associated with increased histone acetylation , reduced DNA methylation and reduced MeCP2 binding at the BDNF promoter .
In concordance , histone acetylation , particularly at the BDNF promoter II , increases BDNF expression .