His experiments are the first published descriptions of the principle of neuraxial blockade .
Also in 1885 , James Leonard Corning ( 1855 -- 1923 ) injected cocaine between the spinous processes of the lower lumbar vertebrae , first in a dog and then in a healthy man .
James Leonard Corning 's experiments are the first published descriptions of the principle of neuraxial blockade .
Also in 1885 , James Leonard Corning ( 1855 -- 1923 ) injected cocaine between the spinous processes of the lower lumbar vertebrae , first in a dog and then in a healthy man .