However , the exact mechanism of how the binding of iproniazid derivatives to liver proteins would induce liver necrosis remains unclear .
Covalent binding results in liver necrosis by presumably changing protein function leading to organelle stress and acute toxicity .
The exact mechanism of how the binding of iproniazid derivatives to liver proteins would induce liver necrosis remains unclear .
Covalent binding results in liver necrosis by presumably changing protein function leading to organelle stress and acute toxicity .