In neuronal tissue , STIM2 plays a crucial role in ischemia - induced neuronal damage .
The absence of STIM2 in knockout mice reduced the neuronal damage produced by ischemia after transient interruption of blood flow in brain .
In neuronal tissue , STIM2 plays a crucial role in ischemia - induced neuronal damage , and the absence of STIM2 in knockout mice reduced the neuronal damage produced by ischemia after transient interruption of blood flow in brain .