In 1884 , Austrian ophthalmologist Karl Koller ( 1857 -- 1944 ) instilled a 2 % solution of cocaine into his own eye .
In 1884 , Austrian ophthalmologist Karl Koller ( 1857 -- 1944 ) tested its effectiveness as a local anesthetic by pricking the eye with needles .
In 1884 , Austrian ophthalmologist Karl Koller ( 1857 -- 1944 ) instilled a 2 % solution of cocaine into his own eye and tested its effectiveness as a local anesthetic by pricking the eye with needles .