Over the years 1670 -- 1710 , the Five Nations achieved political dominance of much of Virginia west of the Fall Line .
Over the years 1670 -- 1710 , the Five Nations extending to the Ohio River valley in present - day West Virginia and Kentucky .
Over the years 1670 -- 1710 , the Five Nations achieved political dominance of much of Virginia west of the Fall Line and extending to the Ohio River valley in present - day West Virginia and Kentucky .