Mutations in the ALPL gene lead to varying low activity of the enzyme tissue - nonspecific alkaline phosphatase ( TNSALP ) resulting in hypophosphatasia ( HPP ) .
is changed in the ALPL gene .
Mutations in the ALPL gene lead to varying low activity of the enzyme tissue - nonspecific alkaline phosphatase ( ALPL ) resulting in hypophosphatasia ( HPP ) .
is changed in the ALPL gene .