It shows a significant sequence divergence between both isoforms and in STIM1 , the C - terminal region is essential for the interaction with SOC channels .
Besides the N - terminus , the C - terminal region is also an essential part of STIM proteins .
STIM shows a significant sequence divergence between both isoforms and in STIM1 , the C - terminal region is essential for the interaction with SOC channels .
Besides the N - terminus , the C - terminal region is also an essential part of STIM proteins .