Endothelins are implicated in vascular diseases of several organ systems , including the heart , lungs , kidneys , and brain .
Endothelins are 21 - amino acid vasoconstricting peptides produced primarily in the endothelium having a key role in vascular homeostasis .
peptides are implicated in vascular diseases of several organ systems , including the heart , lungs , kidneys , and brain .
Endothelins are 21 - amino acid vasoconstricting peptides produced primarily in the endothelium having a key role in vascular homeostasis .