The most significant difference in side effects of loprazolam and diazepam is it is less prone to day time sedation as the half - life of loprazolam is considered to be intermediate .
Diazepam has a very long half - life .
The most significant difference in side effects of loprazolam and diazepam is it is less prone to day time sedation as the half - life of loprazolam is considered to be intermediate whereas diazepam has a very long half - life .