Threshold Entertainment 's production on a second sequel was initially scheduled to commence shortly after the release of Annihilation .
Annihilation was shelved due to Annihilation 's poor reception and disappointing box - office performance .
Threshold Entertainment 's production on a second sequel was initially scheduled to commence shortly after the release of Annihilation , but it was shelved due to Annihilation 's poor reception and disappointing box - office performance .