The plague took nearly 11,000 Londoners .
However , The 1592 -- 4 period was difficult for the acting companies of London ; a severe outbreak of bubonic plague meant that the London theatres were closed almost continuously from June 1592 to May 1594 .
The plague took nearly 11,000 London .
However , The 1592 -- 4 period was difficult for the acting companies of London ; a severe outbreak of bubonic plague meant that the London theatres were closed almost continuously from June 1592 to May 1594 .