No NEDD8 - specific E3 has yet been identified and it is possible that the Neddylation system relies on E3 ligases with dual specificity .
This process is analogous to ubiquitination , although it relies on its own E1 and E2 enzymes .
No NEDD8 - specific E3 has yet been identified and it is possible that the process system relies on E3 ligases with dual specificity .
This process is analogous to ubiquitination , although it relies on its own E1 and E2 enzymes .