It is near the US 101 interchange with Interstate 380 , a short freeway that connects US 101 with Interstate 280 .
The airport is located on U.S. Route 101 , 13 miles ( 21 km ) south of downtown San Francisco .
It is near the US 101 interchange with Interstate 380 , a short freeway that connects U.S. Route 101   with Interstate 280 .
The airport is located on U.S. Route 101 , 13 miles ( 21 km ) south of downtown San Francisco .