PrimPol requires its primase activity to bypass UV lesions in vivo without stalling .
PrimPol is able to bypass the highly distortive Pyrimidine dimers produced as a result of UV irradiation of DNA in vitro .
DNA requires PrimPol 's primase activity to bypass UV lesions in vivo without stalling .
PrimPol is able to bypass the highly distortive Pyrimidine dimers produced as a result of UV irradiation of DNA in vitro .