Mutations to the V - ATPase ' a4 ' or ' B1 ' isoforms result in distal renal tubular acidosis in some cases with sensorineural deafness .
Distal renal tubular acidosis is a condition that leads to metabolic acidosis .
Mutations to the V - ATPase ' a4 ' or ' B1 ' isoforms result in distal renal tubular acidosis , a condition that leads to metabolic acidosis , in some cases with sensorineural deafness .