Infants also tend to have a larger volume of distribution due to their higher concentration of extracellular fluid , where aminoglycosides reside .
In general , amikacin should be avoided in infants .
Infants also tend to have a larger volume of distribution due to infants ' higher concentration of extracellular fluid , where aminoglycosides reside .
In general , amikacin should be avoided in infants .