Meanwhile , in light of Otto 's stroke , members of a Kansas City - based syndicate make plans to move on Fargo .
At home , Lou deals with his wife Betsy 's ( Cristin Milioti ) progressing cancer .
In light of Otto 's stroke , members of a Kansas City - based syndicate make plans to move on Fargo .
At home , Lou deals with his wife Betsy 's ( Cristin Milioti ) progressing cancer .