However , oral clonidine can take up to 45 minutes to take full effect , and drawbacks include hypotension and bradycardia .
In children , clonidine premedication is at least as effective as benzodiazepines and has less serious side effects .
Oral clonidine can take up to 45 minutes to take full effect , and drawbacks include hypotension and bradycardia .
In children , clonidine premedication is at least as effective as benzodiazepines and has less serious side effects .