Thus , it has come to be known as the Regional Trade and Industrial Center of north - eastern Luzon .
Strategically located at the center of Cagayan Valley region , Isabela is acknowledged to have demonstrated strengths in business and industry .
Isabela has come to be known as the Regional Trade and Industrial Center of north - eastern Luzon .
Strategically located at the center of Cagayan Valley region , Isabela is acknowledged to have demonstrated strengths in business and industry .