As such , the oral bioavailability of estradiol valerate is only around 3 to 5 % .
Is comparable to that of micronized estradiol ( which has similarly improved bioavailability relative to ( non-micronized ) oral estradiol ) .
As such , the oral bioavailability of estradiol valerate is only around 3 to 5 % , and is comparable to that of micronized estradiol ( which has similarly improved bioavailability relative to ( non-micronized ) oral estradiol ) .