Her father Ranuccio had previously been married to Margaret Yolande of Savoy .
The marriage produced no surviving issue ; as such , Margherita Maria was the first of Ranuccio 's children to survive infancy .
Her father Ranuccio had previously been married to Margaret Yolande of Savoy but the marriage produced no surviving issue ; as such , Margherita Maria was the first of Ranuccio 's children to survive infancy .