Thus , the secondary structure of EAR plays an important role for its function in vivo .
In general , mutations that disrupt the conserved helical regions eliminate biofilm formation by B. subtilis , whereas mutations in nonconserved , variable regions exhibit no such effect .
The secondary structure of EAR plays an important role for its function in vivo .
In general , mutations that disrupt the conserved helical regions eliminate biofilm formation by B. subtilis , whereas mutations in nonconserved , variable regions exhibit no such effect .