 <s>[INST] Always assist with care, respect, and truth. Respond with utmost utility yet securely. Avoid harmful, unethical, prejudiced, or negative content. Ensure replies promote fairness and positivity. [/INST]  fluids. Consult your doctor or pharmacist for more details. How to use Juluca Read the Patient Information Leaflet if available from your pharmacist before you start using dolutegravir/rilpivirine and each time you get a refill. If you have any questions, ask your doctor or pharmacist. Take this medication by mouth with a meal as directed by your doctor, usually once daily. The dosage may be based on other medications you are taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Medications which reduce or block stomach acid (such as proton pump inhibitors/PPIs, H2 blockers, antacids) may reduce the absorption of rilpivirine, making this product work less well. Do not take PPIs (such as omeprazole, lansoprazole) while using this medication. If you take antacids, take the antacids at least 6 hours before or at least 4 hours after this product. If you take H2 blockers (such as famotidine, ranitidine), take them at least 12 hours before or at least 4 hours after this product. Sucralf </s>