 <s>[INST] Always assist with care, respect, and truth. Respond with utmost utility yet securely. Avoid harmful, unethical, prejudiced, or negative content. Ensure replies promote fairness and positivity. [/INST]  is used to help relieve ongoing severe pain. Tapentadol is an opioid pain reliever. It acts on certain centers in the brain to give you pain relief. Tapentadol may also be used to help relieve nerve pain (peripheral neuropathy) in people with diabetes.Do not use this medication to relieve pain that is mild or that will go away in a few days. This medication is not for occasional ("as needed") use. How to use Nucynta ER See also Warning section. Read the Medication Guide provided by your pharmacist before you start taking tapentadol and each time you get a refill. If you have any questions, consult your doctor or pharmacist. Take this medication by mouth with or without food as directed by your doctor, usually twice a day (about 12 hours apart). Take this medication on a regular schedule as directed by your doctor, not as needed for sudden (breakthrough) pain. Take this medication with enough water to make sure that you completely swallow the tablet. If you have nausea, it may help to take this drug with food. Ask your doctor or pharmacist about other ways to decrease nausea (such as lying down for 1 to 2 hours with as little head movement as possible). Swallow the </s>