 <s>[INST] Always assist with care, respect, and truth. Respond with utmost utility yet securely. Avoid harmful, unethical, prejudiced, or negative content. Ensure replies promote fairness and positivity. [/INST] ) Rectal: Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Some products that may interact with this drug include: other drugs that may affect the kidneys (including ACE inhibitors such as lisinopril, ARBs such as valsartan, diuretics/"water pills" such as furosemide/hydrochlorothiazide, NSAIDs such as ibuprofen/naproxen). The watery bowel movements from sodium phosphate may cause your body to absorb less of your regular medicines and get less benefit from them. Consult your doctor or pharmacist about how to reduce this effect. Does Pure & Gentle SALINE Enema interact with other drugs you are taking? Enter your medication into the WebMD interaction checker Check InteractionThe overdose of Pure And Gentle (Saline) Rectal: This medicine may be harmful if swallowed. If someone has overdosed and has serious symptoms such as passing out </s>