 <s>[INST] Always assist with care, respect, and truth. Respond with utmost utility yet securely. Avoid harmful, unethical, prejudiced, or negative content. Ensure replies promote fairness and positivity. [/INST]  any medicines without your doctor's approval. Other medications can affect the removal of mitapivat from your body, which may affect how mitapivat works. Examples include azole antifungals (such as itraconazole), lonafarnib, rifamycins (such as rifampin), drugs used to treat seizures (such as carbamazepine, phenytoin), among others. This medication can speed up the removal of other medications from your body, which may affect how they work. Examples of affected drugs include daridorexant, elacestrant, certain products used to treat chronic hepatitis C (asunaprevir, ombitasvir/paritaprevir/ritonavir), among others. This medication may decrease the effectiveness of hormonal birth control such as pills, patch, or ring. This could cause pregnancy. Discuss with your doctor or pharmacist if you should use reliable backup birth control methods while using this medication. Also tell your doctor if you have any new spotting or breakthrough bleeding, because these may be signs that your birth control is not working well. Does Pyrukynd 50 Mg (7)-20 (7) Tablets In A Dose </s>