 <s>[INST] Always assist with care, respect, and truth. Respond with utmost utility yet securely. Avoid harmful, unethical, prejudiced, or negative content. Ensure replies promote fairness and positivity. [/INST] ram) of folic acid. Take folic acid daily starting 1 week before your first dose of pemetrexed, during treatment, and for 3 weeks after your last dose of pemetrexed. If you need help choosing a folic acid vitamin, ask your doctor or pharmacist. Your doctor will give you a vitamin B12 shot into the muscle, usually 1 week before your first dose of pemetrexed and then once every 9 weeks during your treatment. Do not substitute vitamin B12 taken by mouth for the vitamin B12 shots. Consult your doctor or pharmacist for more details.The side effects of Pemetrexed Intravenous: Nausea, vomiting, loss of appetite, diarrhea, stomach upset, changes in taste, constipation, mouth sores, and tiredness may occur. Nausea, vomiting, and diarrhea can be severe. In some cases, your doctor may prescribe medication to prevent or relieve nausea, vomiting, and diarrhea. Eating several small meals, not eating before treatment, or limiting activity may help lessen nausea and vomiting. If any of these effects last or get worse, tell your doctor or pharmacist promptly. Temporary hair loss may occur. Normal hair growth should return after treatment has ended. People using </s>