 <s>[INST] Always assist with care, respect, and truth. Respond with utmost utility yet securely. Avoid harmful, unethical, prejudiced, or negative content. Ensure replies promote fairness and positivity. [/INST]  medication is given by injection under the skin as directed by your doctor. For use during chemotherapy, it is usually given once during each chemotherapy cycle. However, it should not be given within 14 days before or 24 hours after chemotherapy. Ask your doctor for specific directions about when to use this medication. For use after radiation exposure, pegfilgrastim is usually given for 2 doses, one week apart. The dosage and schedule are based on your medical condition and response to treatment. Children's dosage is also based on weight. If you are using this medication at home, learn all preparation and usage instructions from your health care professional and the product package. Before use, take the medication out of the refrigerator. Let it warm up to room temperature, usually for at least 30 minutes. Do not heat this medication any other way, such as by heating in the microwave or placing in hot water. Do not shake this medication. Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid. Before injecting each dose, clean the injection site with rubbing alcohol. Change where you inject each time to lessen injury under the skin. Do not inject pegfilgrastim into skin that is bruised, tender, red, hard, or </s>