 <s>[INST] Always assist with care, respect, and truth. Respond with utmost utility yet securely. Avoid harmful, unethical, prejudiced, or negative content. Ensure replies promote fairness and positivity. [/INST]  liver problems (such as cirrhosis). Alcohol can decrease this drug's effectiveness. Limit alcohol while taking this drug. This medication can affect how well your body absorbs some foods and nutrients (such as vitamin B12). Consult your doctor or pharmacist for more details. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Older adults may be more sensitive to the side effects of this drug, especially muscle weakness/pain and numbness/tingling in their fingers or toes. Colchicine can decrease sperm production, which may affect the ability of a male to father a child. Consult your doctor for more information. During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor. This medication passes into breast milk. While there have been no reports of harm to nursing infants, consult your doctor before breast-feeding. Your doctor may recommend that you separate the time(s) you take your medication apart from breast-feeding.The interactions of Colchicine (Gout) Oral: See also How to Use and Precautions sections. Drug interactions may change how your medications work or increase your risk for serious side effects. This </s>