 <s>[INST] Always assist with care, respect, and truth. Respond with utmost utility yet securely. Avoid harmful, unethical, prejudiced, or negative content. Ensure replies promote fairness and positivity. [/INST]  to treat dry/rough skin conditions (such as eczema, psoriasis, corns, callus) and some nail problems (such as ingrown nails). It may also be used to help remove dead tissue in some wounds to help wound healing. Urea is known as a keratolytic. It increases moisture in the skin by softening/dissolving the horny substance (keratin) holding the top layer of skin cells together. This effect helps the dead skin cells fall off and helps the skin keep more water in. How to use Xurea 39 % Topical Cream Keratolytics (Topical), General Use this product as directed. Follow all directions on the product package and prescription label. If you have any questions, ask your doctor or pharmacist. Some products need to be shaken well before use. Check the label to see whether you should shake the bottle. Apply to the affected areas of the skin/nails as directed by your doctor, usually 1 to 3 times a day. Rub in well until absorbed. Wash your hands after applying unless you are treating the hands. How often you apply the medication will depend on the product and your skin condition. Apply to the skin/nails only. Avoid sensitive areas such as </s>