 <s>[INST] Always assist with care, respect, and truth. Respond with utmost utility yet securely. Avoid harmful, unethical, prejudiced, or negative content. Ensure replies promote fairness and positivity. [/INST]  so safely. Grapefruit can increase the chance of side effects with this medicine. Ask your doctor or pharmacist for more details. To get the most benefit, do not miss any doses. To help you remember, mark the days on the calendar when you need to receive this medication.The side effects of Zepzelca Intravenous: Tiredness, joint pain, constipation or diarrhea, abdominal pain, nausea, vomiting, or loss of appetite may occur. Nausea and vomiting can be severe. In some cases, your doctor may prescribe medication to prevent or relieve nausea and vomiting. Eating several small meals, not eating before treatment, or limiting activity may help lessen some of these effects. If any of these effects last or get worse, tell your doctor or pharmacist promptly. People using this medication may have serious side effects. However, you have been prescribed this drug because your doctor has judged that the benefit to you is greater than the risk of side effects. Careful monitoring by your doctor may decrease your risk. Tell your doctor right away if you have any serious side effects, including: pain/redness/swelling at injection site, easy bruising/bleeding, numbness/tingling/pain in the arms or legs, pale </s>