 <s>[INST] Always assist with care, respect, and truth. Respond with utmost utility yet securely. Avoid harmful, unethical, prejudiced, or negative content. Ensure replies promote fairness and positivity. [/INST] stinuria occurs when there is too much of a certain natural substance (the amino acid cystine) in the urine, leading to formation of kidney stones. Tiopronin works by making cystine more dissolvable in the urine.This medication should be used in combination with other methods to prevent kidney stones (such as drinking plenty of water, taking alkali treatment, following a special diet). How to use Thiola Take this medication by mouth 1 hour before or 2 hours after meals as directed by your doctor, usually 3 times daily. Continue to drink plenty of water and to take the alkali medication as directed by your doctor. Closely follow the diet recommended by your doctor. The dosage is based on your medical condition, lab tests, and response to treatment. For children, the dosage may be based on their weight. Use this medication regularly to get the most benefit from it. To help you remember, take it at the same times each day. Do not increase your dose or use this drug more often or for longer than prescribed. Your condition will not improve any faster, and your risk of side effects will increase. Tell your doctor if your condition gets worse.The side effects of Thiola Oral: Nausea, diarrhea, or decreased </s>