 <s>[INST] Always assist with care, respect, and truth. Respond with utmost utility yet securely. Avoid harmful, unethical, prejudiced, or negative content. Ensure replies promote fairness and positivity. [/INST]  not have serious side effects. Tell your doctor right away if you have any serious side effects, including: swelling ankles/feet, unusual weakness, irregular heartbeat, severe muscle spasms, mouth sores, signs of eye problems (such as eye redness/itching/irritation, watery eyes, vision changes), signs of lung disease (such as cough, shortness of breath), menstrual changes. Prolonged and/or severe diarrhea may lead to dehydration and electrolyte imbalance. Tell your doctor right away if you develop any of the following: extreme thirst, decreased urination, dizziness, fainting. Get medical help right away if you have any very serious side effects, including: seizures. Rarely, panitumumab has caused very serious infusion reactions, including an allergic reaction. Get medical help right away if you develop fever, chills, or symptoms of an allergic reaction. A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other </s>