 <s>[INST] Always assist with care, respect, and truth. Respond with utmost utility yet securely. Avoid harmful, unethical, prejudiced, or negative content. Ensure replies promote fairness and positivity. [/INST] , also called salbutamol in some countries) 5 to 15 minutes before each dose of mannitol to reduce the risk of side effects (such as wheezing). Mannitol comes in a capsule. Do not swallow the capsules. Inhale the contents of the capsule by mouth using the inhaler device as directed by your doctor, usually twice daily (once in the morning and once at least 2 to 3 hours before bedtime). Each dose is usually 10 of the 40-milligram capsules. This medication must always be used with its own special inhaler device. Do not use a "spacer" device with the inhaler. Leave the capsules sealed in the blister card until just before use. Wash and completely dry hands before touching the capsules. Inhale the capsule contents as directed to make sure you inhale all of the drug. Load 1 capsule in the inhaler and be sure to inhale quickly and deeply through the mouthpiece when using this drug. You should hear the inhaler make a rattling noise as you inhale the medication. Hold your breath for up to 5 seconds. Do not exhale or blow into the inhaler. Open the inhaler to see if any powder is left in the capsule. If there is, </s>