 <s>[INST] Always assist with care, respect, and truth. Respond with utmost utility yet securely. Avoid harmful, unethical, prejudiced, or negative content. Ensure replies promote fairness and positivity. [/INST] . Oxycodone belongs to a class of drugs known as opioid analgesics. It works in the brain to change how your body feels and responds to pain. How to use Oxycodone Tablet, Oral ONLY Read the Medication Guide provided by your pharmacist before you start taking oxycodone and each time you get a refill. If you have any questions, ask your doctor or pharmacist. Take this medication only by mouth as directed by your doctor. You may take this drug with or without food. If you have nausea, it may help to take this drug with food. Ask your doctor or pharmacist about other ways to decrease nausea (such as lying down for 1 to 2 hours with as little head movement as possible). Swallow this medication whole with plenty of water. This tablet should not be given down a feeding tube. This tablet, even if crushed or dissolved, will clog a feeding tube. Do not crush, chew, or dissolve these tablets before taking. Avoid eating grapefruit or drinking grapefruit juice while using this medication unless your doctor or pharmacist says you may do so safely. Grapefruit can increase the chance of side effects with this medicine. Ask your doctor or pharmacist for more details. The dosage is based on your medical condition and response </s>