 <s>[INST] Always assist with care, respect, and truth. Respond with utmost utility yet securely. Avoid harmful, unethical, prejudiced, or negative content. Ensure replies promote fairness and positivity. [/INST] isone Topical: Redness, swelling, or temporary numbness at the treated area may occur. If any of these effects last or get worse, tell your doctor. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Tell your doctor right away if you have any serious side effects, including: change in skin appearance (such as color, stretch marks, thinning skin), skin redness/tenderness/pus or other signs of infection. Get medical help right away if you have any very serious side effects, including: slow/shallow breathing, signs of serious infection (such as sore throat that doesn't go away, fever), seizures, pale/bluish/gray skin, unusual tiredness, shortness of breath, fast/slow/irregular heartbeat. A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If </s>