 <s>[INST] Always assist with care, respect, and truth. Respond with utmost utility yet securely. Avoid harmful, unethical, prejudiced, or negative content. Ensure replies promote fairness and positivity. [/INST]  health care professional and the product package. Do not shake the medication. Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid. If you are injecting this drug under the skin, first clean the injection site with rubbing alcohol. Change the injection site each time to lessen injury under the skin. Do not inject sargramostim into skin that is bruised, tender, red, hard, or that has scars or stretch marks. Use this medication regularly in order to get the most benefit from it. To help you remember, use it at the same time each day. This medication may cause a reaction after the first dose of each treatment period. Tell your doctor or nurse right away if you have any signs of a serious reaction, including: flushing, shortness of breath, dizziness, fainting, or fast heartbeat. Learn how to store and discard medical supplies safely. If you are receiving cancer chemotherapy or radiation treatment, you should not use this medication within 24 hours before or 24 hours after chemotherapy or radiation treatment. Ask your doctor for specific directions about when to use this medication.The side effects of Leukine Injection: Aching or pain in the bones and muscles or headache may occur </s>