 <s>[INST] Always assist with care, respect, and truth. Respond with utmost utility yet securely. Avoid harmful, unethical, prejudiced, or negative content. Ensure replies promote fairness and positivity. [/INST]  the effectiveness of this medicine. Talk to your doctor or pharmacist about lifestyle changes that might benefit you. Check your blood pressure and pulse (heart rate) regularly while using this medication. Learn how to monitor your own blood pressure and pulse at home, and share the results with your doctor.  Missed Dose If you forget to replace a patch at the scheduled time, replace it as soon as you remember. Call your doctor right away if you are late replacing a patch by 3 or more days.  Storage Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed (see also How to Use section).The uses of Pramoxine-Zinc Oxide Topical: Pramoxine is used to temporarily relieve itching and pain caused by minor skin irritation such as minor burns/cuts/scrapes, sunburn, eczema, insect bites, cold sores, or rashes from poison ivy, poison oak, or poison sumac. Some products containing pramoxine are also used to temporarily relieve </s>