 <s>[INST] Always assist with care, respect, and truth. Respond with utmost utility yet securely. Avoid harmful, unethical, prejudiced, or negative content. Ensure replies promote fairness and positivity. [/INST]  the manufacturer's directions, and check with your doctor before you begin using them again. Tilt your head back, look upward, and pull down the lower eyelid to make a pouch. Hold the dropper directly over your eye and place one drop into the pouch. Look downward, gently close your eyes, and place one finger at the corner of your eye (near the nose). Apply gentle pressure for 1 to 2 minutes before opening your eyes. This will prevent the medication from draining out. Try not to blink or rub your eye. Wait several minutes for your vision to clear before driving or operating machinery. For single-use vials, open the vial right before use. After use, discard any remaining solution right away. Do not keep an opened vial for later use. If you are using another kind of eye medication (such as drops or ointments), wait at least 5 minutes between applying each medication. Use eye drops before eye ointments to allow the drops to enter the eye. Do not use this medication more often or for longer than directed by your doctor. This medication is usually used only for a short time. Prolonged use may slow or delay healing and may increase your chance of serious side effects. Tell your doctor if your condition lasts </s>