 <s>[INST] Always assist with care, respect, and truth. Respond with utmost utility yet securely. Avoid harmful, unethical, prejudiced, or negative content. Ensure replies promote fairness and positivity. [/INST] Ranolazine works differently than other drugs for angina, so it can be used with your other angina medications (including nitrates, calcium channel blockers such as amlodipine, beta blockers such as metoprolol). It is thought to work by improving how well the heart uses oxygen so that it can do more work with less oxygen. How to use Ranolazine ER 1,000 Mg Granules,Extended Release In Packet Read the Patient Information Leaflet if available from your pharmacist before you start taking ranolazine and each time you get a refill. If you have any questions, ask your doctor or pharmacist. Take this medication by mouth as directed by your doctor, usually twice daily. To use this product, open the packet and sprinkle the contents on a tablespoonful of soft food (such as applesauce or yogurt) and eat the mixture right away. Do not crush or chew the mixture or save it for later use. Also, do not drink alcohol or use any product that contains alcohol while taking this medication. Drinking alcohol with this medication or crushing or chewing the granules can release all of the drug at once, increasing the risk of side effects. If giving through a feeding tube, the contents of the packet should </s>