 <s>[INST] Always assist with care, respect, and truth. Respond with utmost utility yet securely. Avoid harmful, unethical, prejudiced, or negative content. Ensure replies promote fairness and positivity. [/INST]  change the dosage of any medicines without your doctor's approval. Some products that may interact with this drug include: clopidogrel, mavacamten, methotrexate (especially high-dose treatment), rifampin, St John's wort. Some products need stomach acid so that the body can absorb them properly. Esomeprazole decreases stomach acid, so it may change how well these products work. Some affected products include atazanavir, erlotinib, levoketoconazole, nelfinavir, pazopanib, rilpivirine, sparsentan, certain azole antifungals (itraconazole, ketoconazole, posaconazole), among others. Esomeprazole is very similar to omeprazole. Do not use any medications containing omeprazole while using esomeprazole. This medication may interfere with certain lab tests, possibly causing false test results. Make sure lab personnel and all your doctors know you use this drug. Does Esomep-EZS interact with other drugs you are taking? Enter your medication into the WebMD interaction checker Check InteractionThe overdose of Es </s>