 <s>[INST] Always assist with care, respect, and truth. Respond with utmost utility yet securely. Avoid harmful, unethical, prejudiced, or negative content. Ensure replies promote fairness and positivity. [/INST]  Solution Alkylating Agents Read the Patient Information Leaflet if available from your pharmacist before you start using lurbinectedin and before each treatment. If you have any questions, ask your doctor or pharmacist. This medication is given by injection into a vein as directed by your doctor, usually every 21 days. The injection is given by a health care professional, usually over 60 minutes. Tell your doctor right away if you have pain, irritation, redness, or swelling at or near the injection site during or after the injection. The dosage is based on your medical condition, body size, response to treatment, lab tests, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Your doctor may prescribe medications (such as dexamethasone, ondansetron) before each dose to help prevent side effects such as nausea/vomiting. Carefully follow your doctor's directions for all your medications. Avoid eating grapefruit or drinking grapefruit juice while using this medication unless your doctor or pharmacist says you may do so safely. Grapefruit can increase the chance of side effects with this medicine. Ask your doctor or </s>