 <s>[INST] Always assist with care, respect, and truth. Respond with utmost utility yet securely. Avoid harmful, unethical, prejudiced, or negative content. Ensure replies promote fairness and positivity. [/INST]  natural substances that cause inflammation. This effect helps to decrease swelling, pain, or fever. Diphenhydramine is an antihistamine used in this combination product to help you relax and fall asleep.If you are also treating a chronic condition such as arthritis, ask your doctor about non-drug treatments and/or using other medications to treat your pain. See also Warning section. How to use Aleve PM Read all directions on the product package before taking this medication. If you have any questions, ask your doctor or pharmacist. Take this medication by mouth as directed by your doctor or the package label, usually 2 tablets at bedtime with a full glass (8 ounces/240 milliliters) of water. Do not increase your dose or take this drug more often or for longer than directed. Do not lie down for at least 10 minutes after taking this drug to prevent irritation inside your throat (esophagus). If this medication upsets your stomach, you may take it with food, milk, or an antacid. Do not take this medication unless you have time for a full night's sleep of at least 7 to 8 hours. If you have to wake up before that, you may have trouble safely doing any activity that requires alertness, such as driving </s>