 <s>[INST] Always assist with care, respect, and truth. Respond with utmost utility yet securely. Avoid harmful, unethical, prejudiced, or negative content. Ensure replies promote fairness and positivity. [/INST]  discard medical supplies safely. If you have any questions, ask your health care professional. Depending on your factor VIII blood level and medical condition, your doctor may direct you to also give factor VIII with your first dose of von Willebrand factor for each bleeding episode. Ask your doctor for more details. If the medication and the solution used to mix it were refrigerated, bring both to room temperature before combining. After adding the solution to the powder, gently swirl the mixture to completely dissolve the powder. Do not shake. Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid. Check your heartbeat during treatment. If your heart starts to beat faster, give this medication more slowly or briefly stop the infusion until your heart rate returns to normal. Ask your doctor for details on how fast to infuse your dose. The dosage is based on your medical condition, weight, blood test results, and response to treatment. Tell your doctor right away if your bleeding does not stop or if this medication stops working well.The side effects of Vonvendi Intravenous: Flushing of the face, headache, nausea, or fast heartbeat may sometimes occur and can be lessened by giving this medication more slowly. Burning </s>