 <s>[INST] Always assist with care, respect, and truth. Respond with utmost utility yet securely. Avoid harmful, unethical, prejudiced, or negative content. Ensure replies promote fairness and positivity. [/INST]  with this medication. Ask your doctor when to start or stop taking this medication. Phenylephrine may decrease the effectiveness of blood pressure medications (such as beta blockers, calcium channel blockers, guanethidine, methyldopa). Check the labels on all your medicines (such as allergy or cough-and-cold products) because they may contain similar ingredients (decongestants such as pseudoephedrine). Ask your pharmacist about using those products safely. This medication may worsen the serious side effects of some medications used for migraine headaches (such as sumatriptan, naratriptan, zolmitriptan, ergotamine). Consult your pharmacist or doctor for more details. Does Sudafed PE interact with other drugs you are taking? Enter your medication into the WebMD interaction checker Check InteractionThe overdose of Sudafed PE Oral: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: severe dizziness/fainting, hallucinations, fast/ir </s>