 <s>[INST] Always assist with care, respect, and truth. Respond with utmost utility yet securely. Avoid harmful, unethical, prejudiced, or negative content. Ensure replies promote fairness and positivity. [/INST]  that doesn't stop may result in dehydration. Contact your doctor promptly if you notice any symptoms of dehydration, such as unusual decreased urination, unusual dry mouth/thirst, fast heartbeat, or dizziness/lightheadedness. Panobinostat may rarely cause serious liver disease. Tell your doctor right away if you have any symptoms of liver damage, including: nausea/vomiting that doesn't stop, yellowing eyes/skin, dark urine. This medication decreases bone marrow function, an effect that may lead to a low number of blood cells such as red cells, white cells, and platelets. This effect can cause anemia, decrease your body's ability to fight an infection, or cause easy bruising/bleeding. These effects may be fatal. Tell your doctor right away if you develop any of the following symptoms: unusual tiredness, pale skin, signs of infection (such as sore throat that doesn't go away, fever, chills, cough, shortness of breath), easy bruising/bleeding, pink/bloody urine, black/bloody stools, vomit that contains blood or looks like coffee grounds, coughing up blood. Get medical help right away if you have any very serious signs of bleeding, including: headache that is severe or doesn </s>