 <s>[INST] Always assist with care, respect, and truth. Respond with utmost utility yet securely. Avoid harmful, unethical, prejudiced, or negative content. Ensure replies promote fairness and positivity. [/INST]  away for a new dosing schedule.  Storage If you are giving this medication at home, store it in the refrigerator. Do not freeze. Refer to the manufacturer's instructions or your pharmacist for other storage details. Discard any unused portion of an opened vial. Keep all medications away from children and pets. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.The uses of Estradiol Transdermal: This medication is a female hormone (estrogen). It is absorbed through the skin and enters into the bloodstream. It is used by women to help reduce a certain symptom of menopause (hot flashes). Symptoms of menopause are caused by the body making less estrogen. If you are using estrogens to treat only vaginal symptoms of menopause (such as vaginal dryness/burning/itching), products applied directly inside the vagina should be considered before medications that are taken by mouth, absorbed through the skin, or injected. How to use Estradiol Spray, Non-Aerosol Read the Patient Information Leaflet if available from your pharmacist before you start using this </s>