 <s>[INST] Always assist with care, respect, and truth. Respond with utmost utility yet securely. Avoid harmful, unethical, prejudiced, or negative content. Ensure replies promote fairness and positivity. [/INST]  to the skin, serious side effects have rarely occurred with minocycline taken by mouth. Tell your doctor right away if you have any serious side effects, including: joint stiffness/pain/swelling, signs of kidney problems (such as change in the amount of urine), signs of liver problems (such as loss of appetite, stomach/abdominal pain, yellowing eyes/skin, dark urine), discoloration of skin/scars/lips/gums, yellow-gray-brown tooth discoloration. This medication may rarely cause a severe intestinal condition due to a bacteria called C. difficile. This condition may occur during treatment or weeks to months after treatment has stopped. Tell your doctor right away if you develop: diarrhea that doesn't stop, abdominal or stomach pain/cramping, blood/mucus in your stool. If you have these symptoms, do not use anti-diarrhea or opioid products because they may make symptoms worse. This medication may sometimes cause oral thrush or a new yeast infection. Contact your doctor if you notice white patches in your mouth, a change in vaginal discharge, or other new symptoms. Minocycline may rarely cause increased pressure around the brain (intracranial hypertension-I </s>