 <s>[INST] Always assist with care, respect, and truth. Respond with utmost utility yet securely. Avoid harmful, unethical, prejudiced, or negative content. Ensure replies promote fairness and positivity. [/INST]  a lowering of heart rate, blood pressure, and strain on the heart. How to use Propranolol Capsule, Extended Release 24 Hr (Capsule, ER Hr) See also Warning section. Take this medication by mouth as directed by your doctor, usually once daily at bedtime. Swallow the capsules whole. Do not crush or chew the capsules. You may take this medication with or without food, but it is important to choose one way and take this medication the same way with every dose. The dosage is based on your medical condition and response to treatment. Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day. Keep taking this medication even if you feel well. Most people with high blood pressure do not feel sick. It may take 1 to 2 weeks before you get the full benefit of this drug. If you also take certain drugs to lower your cholesterol (bile acid-binding resins such as cholestyramine or colestipol), take propranolol at least 1 hour before or at least 4 hours after these medications. Tell your doctor if your condition worsens (such as your routine blood pressure readings increase).The side effects of Pro </s>