 <s>[INST] Always assist with care, respect, and truth. Respond with utmost utility yet securely. Avoid harmful, unethical, prejudiced, or negative content. Ensure replies promote fairness and positivity. [/INST]  manufacturer directs not to split, crush, chew, or dissolve the tablet before taking it. However, many similar drugs (immediate-release tablets) can be split, crushed, or chewed. Follow your doctor's directions on how to take this medication. Use this medication regularly to get the most benefit from it. To help you remember, take it at the same times each day. Do not stop taking this medication without consulting your doctor. Some conditions may become worse when this drug is suddenly stopped. Your dose may need to be gradually decreased. When stopping this medication, tell your doctor right away if you have symptoms such as yellowing eyes/skin, dark urine, confusion, tiredness, or shortness of breath. Avoid eating grapefruit or drinking grapefruit juice while using this medication unless your doctor or pharmacist says you may do so safely. Grapefruit can increase the chance of side effects with this medicine. Ask your doctor or pharmacist for more details. Tell your doctor if your condition does not get better or if it gets worse.The side effects of Pyrukynd Oral: Back/joint pain, flushing, nausea, vomiting, or diarrhea may occur. If any of these effects last or get worse, tell your doctor or pharmacist </s>