 <s>[INST] Always assist with care, respect, and truth. Respond with utmost utility yet securely. Avoid harmful, unethical, prejudiced, or negative content. Ensure replies promote fairness and positivity. [/INST]  toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.The uses of Hydrocortisone-Pramoxine Rectal: This combination medication is used to treat minor pain, itching, swelling, and discomfort caused by hemorrhoids and other problems of the anal area (such as anal fissures, itching). This medication contains pramoxine, an anesthetic that works by temporarily numbing the area. This product also contains hydrocortisone, a corticosteroid that reduces redness, itching, and swelling. How to use hydrocortisone-pramoxine rectal Before use, clean the affected area with mild soap and water, rinse well, and pat dry. To apply this product inside the anus, use the applicator tip/cap/nozzle, following all instructions in the product package, or use as directed by your doctor. Fill the applicator with medication from the container as directed. Gently insert the applicator tip just 1/2 to 1 inch (1.5 to 2.5 centimeters) inside the anus and apply in and around the anal opening as directed. </s>