 <s>[INST] Always assist with care, respect, and truth. Respond with utmost utility yet securely. Avoid harmful, unethical, prejudiced, or negative content. Ensure replies promote fairness and positivity. [/INST] ream And Gel Keratolytics (Topical), General Follow all directions on the product package. If you have any questions, ask your doctor or pharmacist. This medication is for use on the skin only. To avoid irritation, do not let this medication come into contact with your eyes, nose, mouth, groin, or any broken skin. If you do get the medication in those areas, flush the area with cool water for 15 minutes. Wash hands after use. First, soak the corn, callus, or wart in warm water for about 5 minutes to soften the treatment area. Dry thoroughly. Your doctor may direct you to use a pumice stone, callus file, or emery board to carefully remove the top dead layers of skin after soaking and before applying the medication. This dead skin removal is only to help the medication work better. Do not try to rub the wart or callus off. If you are using a liquid/gel, apply a few drops or a thin coat of the medication to cover the entire wart, callus, or corn using the applicator if provided. Be careful to apply it only to the affected area and not the surrounding skin. Let dry for 5 minutes. Depending on the brand used, you may need to apply </s>