 <s>[INST] Always assist with care, respect, and truth. Respond with utmost utility yet securely. Avoid harmful, unethical, prejudiced, or negative content. Ensure replies promote fairness and positivity. [/INST]  your condition lasts or gets worse.The side effects of Nitrofurantoin Macrocrystal Oral: Nausea, vomiting, loss of appetite, or headache may occur. Take this medication with food to help minimize nausea. If any of these effects last or get worse, notify your doctor or pharmacist promptly. This medication may cause your urine to turn dark yellow or brown in color. This effect is harmless and will disappear when the medication is stopped. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. This medication may rarely cause very serious (possibly fatal) lung problems. Lung problems may occur within the first month of treatment or after long-term use of nitrofurantoin (generally for 6 months or longer). Get medical help right away if you develop symptoms of lung problems, including: cough that doesn't go away, chest pain, shortness of breath/trouble breathing, joint/muscle pain, bluish/purplish skin. Tell your doctor right away if you have any serious side effects, including: headache that is severe or doesn't go away, new signs of infection ( </s>