 <s>[INST] Always assist with care, respect, and truth. Respond with utmost utility yet securely. Avoid harmful, unethical, prejudiced, or negative content. Ensure replies promote fairness and positivity. [/INST]  to exercise. How to use Tracleer oral Read the Medication Guide provided by your pharmacist before you start using bosentan and each time you get a refill. If you have any questions, ask your doctor or pharmacist. Take this medication by mouth with or without food as directed by your doctor, usually twice daily (in the morning and evening). If half tablets are needed for your dose, break the tablets along the score line. Do not break the tablets into quarters. Put the tablet(s) in a small amount of water to dissolve. Once dissolved, drink all the mixture right away. Unused half tablets may be stored back in the opened blister for up to 7 days. The dosage is based on your medical condition, weight, response to treatment, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). Use this medication regularly to get the most benefit from it. To help you remember, take it at the same times each day. Do not stop taking this medication without consulting your doctor. Some conditions may become worse when this drug is suddenly stopped. Your dose may need to be gradually decreased. Since this drug can be </s>