André Lespagnol (26 July 1943 – 13 September 2020) was a French politician and professor. He was a professor at the University of Rennes 2, focusing on the history of Saint-Malo. He was President of the University of Rennes 2 from 1991 to 1996. In 2004, he was elected Vice-President of the Regional Council of Brittany, serving until 2010. He was born in Crozon, France.