Hossein Sheikholeslam (; 29 November 1952 – 5 March 2020) was an Iranian politician, activist and diplomat. He was an advisor to the foreign minister Javad Zarif. He also was a member of the Seventh Islamic Parliament of Iran fro 2004 to 2008. He was the Iranian ambassador to Syria from 1998 to 2003. He was born Isfahan, Iran.