George Shuffler (April 15, 1925 – April 7, 2014) was an American bluegrass guitarist. He was an early expert of the crosspicking style. He began his career in 1946. He played with The Bailey Brothers, The Stanley Brothers and Ralph Stanley's Clinch Mountain Boys. In 2007, he received the North Carolina Heritage Award. In 2011, he was elected to the International Bluegrass Music Hall of Fame. He was born in Valdese, North Carolina.