Florence () is the capital city of the region of Tuscany ("Toscana"), in Italy. From 1865 to 1870 the city was also the capital of the Kingdom of Italy. Florence is on the Arno River. The city has a population of around 400,000 people, and a suburban population of over 2,000,000 persons. The greater area has some 956,000 people. The city was a center of medieval European trade and finance. It is often considered the birthplace of the Italian Renaissance and was long ruled by the Medici family. Florence is also famous for its fine art and architecture. It is said that, of the 1,000 most important European artists of the second millennium, 350 lived or worked in Florence.