Henry N. Cobb (April 8, 1926 – 2020) was an American architect. He was a founding partner with I.M. Pei and Eason H. Leonard of Pei Cobb Freed & Partners, an international architectural firm based in New York City. Cobb was born in Boston, Massachusetts. His best known designs were Hyatt Center, John Hancock Tower and U.S. Bank Tower.