Susan Tyrrell (born Susan Jillian Creamer; March 18, 1945 – June 16, 2012) was an American actress, painter, and writer. She is known for her Best Supporting Actress Oscar-nominated performance as Oma in "Fat City", and for her role as Ramona Rickettes in the John Waters movie "Cry-Baby". In 2000, she was diagnosed with thrombocythemia which led to amputation of both her legs below the knee. She spent the years painting and writing.