Garhi Yasin is a town and taluka in the north of Sindh province of Pakistan. It is the second largest town in the Shikarpur District. It is also one of the four divisions of the districts. The town has a population of more than 14,000. Garhi Yasin is on the right bank of River Indus. The area has always been important as a part of the trade route through the Bolan Pass.