James Patrick Allison (born August 7, 1948) is an American immunologist. He is a professor and chair of Immunology and executive director of immunotherapy platform at the M. D. Anderson Cancer Center. His discoveries have led to new cancer treatments for the deadliest cancers. He is also the director of the Cancer Research Institute (CRI). He is thought to be the first person to isolate the T-cell antigen receptor complex protein.