phy is an X-linked peroxisomal disease affecting mostly males, caused drial membrane.
by deficiency in β-oxidation of very-long-chain fatty acids. The build-up The intermembrane space houses cytochrome c, a molecule involved
of very-long-chain fatty acids in the nervous system and suprarenal in activation of apoptosis.
glands determines progressive deterioration of brain function and The number of mitochondria in a particular cell reflects its general
suprarenal insufficiency (Addison’s disease). For further reading, see energy requirements; e.g. in hepatocytes there may be as many as 2000,
Braverman et al (2013). whereas in resting lymphocytes there are usually very few. Mature