- V. Pedro, Jaime CarbonellChair, Eric Nyberg, R. Frederking, Eduard HovyUSC. 2011. THESIS PROPOSAL. Abstract: Resting-state functional MRI (rs-fMRI) is increasingly used for probing functional connectivity of the human brain. The spontaneous activity identified by rs-fMRI plays a key role in understanding the normal brain’s functional organization. It also holds valuable diagnostic and prognostic information towards various neurological or psychiatric diseases including Alzheimer’s disease, depression, schizophrenia, etc [1]. The blood oxygenation level-dependent (BOLD) signal of fMRI detects the locations of increased neuro activity by measuring the blood oxygen levels at consecutive time points. The higher the temporal correlation between two spatially distant regions, the more likely that there is a functional connection between those regions.
