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@@ -27,8 +27,7 @@ Influenza Surveillance and Response System ( GISRS ) and reported to FluNet wa
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  2024.
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  • During the 28 -day period from 11 December 2023 to 7 January , 53 and 42 countries provided data at least
29
  once on COVID -19"
30
- ".
31
- • During the 28 -day period from 11 December 2023 to 7 January , 53 and 42 countries provided data at least
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  once on COVID -19 hospitalizations and admissions to an intensive care unit (ICU) , respectively . From the
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  available data, over 173 000 new hospitalizations and over 1900 new ICU admissions were reported during
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  the 28 -day period . Amongst the countries reporting these data consistently over the current and past
@@ -42,10 +41,9 @@ risk at the global level based on available evidence. WHO is currently tracking
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  five VOIs – XBB.1.5, XBB.1.16 , EG.5 BA.2.86 and JN.1 ; and five VUMs : DV.7, XBB, XBB.1.9.1, XBB .1.9.2 and
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  XBB.2.3
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  • The Global WHO Coronavirus (COVID -19) Dashboard has been updated and adapted with a new interface
45
- on 22 December 2023 to support WHO and Member States’ work to transition from COVID -"
46
- "Coronavirus (COVID -19) Dashboard has been updated and adapted with a new interface
47
  on 22 December 2023 to support WHO and Member States’ work to transition from COVID -19 as an
48
- emergency to longer -term disease management, as outlined in WHO’s 3 May 2023 COVID -19 2023 -2025
 
49
  Updated Strategic Preparedness and Response Plan . The new dashboard will progressively incorporate more
50
  components throughout 2024. The previous link of the Global WHO Coronavirus (COVID -19) Dashboard will
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  still be active and redirect users to the new one from 22 December onward. Please note that start time of
@@ -70,11 +68,10 @@ Global overview
70
 
71
  Data as of 7 January 2024
72
  Globally, the number of new weekly cases remained stable during the 28 -day period of 11 December 2023 to 7
73
- J"
74
- " as of 7 January 2024
75
- Globally, the number of new weekly cases remained stable during the 28 -day period of 11 December 2023 to 7
76
  January 2024 as compared to the previous 28 -day period, with over 1.1 million new cases reported (Figure 1,
77
  Table 1). The number of new weekly deaths decreased by 26% as compared to the previous 28 -day period, with
 
 
78
  8700 new fatalities reported. As of 7 January 2024, over 774 million confirmed cases and over 7 million deaths
79
  have been reported globally. According to estimates obtained from viral loads in wastewater surveillance, clinical
80
  detection of cases underestimated the real burden 2 to 19 -fold1,2,3
@@ -88,14 +85,13 @@ COVID -19, including increases in newly reported cases and, more importantly, in
88
  deaths – the latter of which are considered more reliable indicators given reductions in testing. Global and
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  national data on SARS -CoV-2 PCR percent positivity are available on WHO’s integrated influenza and other
90
  respiratory viruses surveillance dashboard . Recent data (epidemiological week one, 1 to 7 January 2024) from
91
- sentinel sites show that"
92
- "integrated influenza and other
93
- respiratory viruses surveillance dashboard . Recent data (epidemiological week one, 1 to 7 January 2024) from
94
  sentinel sites show that the SARS -CoV-2 PCR percent positivity from reporting countries averages approximately
95
  8% (Figure 2).
96
  As many countries discontinue COVID -19-specific reporting and integrate it into respiratory disease surveillance,
97
  WHO will use all available sources to continue monitoring the COVID -19 epidemiological situation, especially
98
  data on morbidity and impact on h ealth systems. COVID -19 remains a major threat, and WHO urges Member
 
 
99
  States to maintain, not dismantle, their established COVID -19 infrastructure. It is crucial to sustain, inter alia ,
100
  early warning, surveillance and reporting, variant tracking, early clin ical care provision, administration of vaccine
101
  to high -risk groups, improvements in ventilation, and regular communication.
@@ -113,10 +109,6 @@ continuously updated to retrospectively incorporate changes in reported COVID -1
113
  countries.
114
 
115
 
116
- Figure 1. COVID -19 cases and global deaths by 28 -day intervals reported by WHO Region, as of 7 January 2024 ( A); "
117
- "ries.
118
-
119
-
120
  Figure 1. COVID -19 cases and global deaths by 28 -day intervals reported by WHO Region, as of 7 January 2024 ( A); 26
121
  June to 17 January 2024 (B)**
122
 
@@ -130,7 +122,8 @@ B 4
130
  At the regional level, the number of newly reported 28 -day cases decreased across four of the six WHO regions:
131
  the African Region ( -63%), the Region of the Americas ( -18%), the Eastern Mediterranean Region ( -13%), and
132
  the European Region ( -13%); while case numbers increased in two WHO regions: the Western Pacific Region
133
- (+77%), and the South -East Asia Region (+379%). The number of newly reported 28 -day deaths decreased or
 
134
  remained stable across five regions: the African Region ( -113%), the Eastern Mediterra nean Region ( -53%), the
135
  Western Pacific Region ( -45%), the Region of the Americas ( -41%), and the European Region ( -3%); while death
136
  numbers increased in the South -East Asia Region (+564%).
@@ -138,8 +131,6 @@ At the country level, the highest numbers of new 28 -day cases were reported fro
138
  198 new cases; -30%), Singapore (174 643 new cases; +117%), Italy (163 599 new cases; -18%), Greece (68 590
139
  new cases; +81%), and Malaysia (67 206 n ew cases; +164%). The highest numbers of new 28 -day deaths were
140
  reported from Italy (1016 new deaths; -21%), the Russian Federation (679 new deaths; +45%), Poland (543 new
141
- deaths; +229%), Sweden ("
142
- "(1016 new deaths; -21%), the Russian Federation (679 new deaths; +45%), Poland (543 new
143
  deaths; +229%), Sweden (446 new deaths; -47%), and Greece (322 new deaths; +79%).
144
 
145
  Table 1. Newly reported and cumulative COVID -19 confirmed cases and deaths, by WHO Region, as of 7 January 2024**
@@ -162,6 +153,9 @@ last 28 days Countries
162
  reporting
163
  deaths in
164
  the last 28
 
 
 
165
  days
166
  Europe 701 053
167
  (63%) -13% 278 615
@@ -181,12 +175,6 @@ Pacific 338 056
181
  (49%) 8/35
182
  (23%)
183
  America
184
- s 42 330
185
- (4%) -18% 193 223
186
- 732
187
- (25%) 3 86"
188
- "3%)
189
- America
190
  s 42 330
191
  (4%) -18% 193 223
192
  732
@@ -210,6 +198,8 @@ Africa 3 354
210
  (0%) -113% 175 473
211
  (3%) 28/50
212
  (56%) 4/50
 
 
213
  (8%)
214
  Eastern
215
  Mediter
@@ -229,12 +219,6 @@ Global 1 113 726
229
  (45%) 51/234
230
  (22%)
231
 
232
- *Percent"
233
- "7 012 984
234
- (100%) 106/234
235
- (45%) 51/234
236
- (22%)
237
-
238
  *Percent change in the number of newly confirmed cases/deaths in the past 28 days, compared to 28 days prior. Data from previous weeks are
239
  updated continuously with adjustments received from countries.
240
  **See Annex 1: Data, table, and figure notes
@@ -256,7 +240,8 @@ Source: Influenza and SARS -CoV-2 surveillance data from GISRS reported to FluN
256
  **See Annex 1: Data, table, and figure notes
257
 
258
  7
259
- Figure 4. Percentage change in confirmed COVID -19 cases over the last 28 days relative to the previous 28 days, as of 7 January 2024**
 
260
 
261
  **Se e Annex 1: Data, table, and figure notes
262
 
@@ -268,9 +253,6 @@ Source: Influenza and SARS -CoV-2 surveillance data from GISRS reported to FluN
268
  9
269
  Figure 6. Percentage change in confirmed COVID -19 deaths over the last 28 days relative to the previous 28 days, as of 7 January 2024**
270
 
271
- **Se e"
272
- "6. Percentage change in confirmed COVID -19 deaths over the last 28 days relative to the previous 28 days, as of 7 January 2024**
273
-
274
  **Se e Annex 1: Data, table, and figure notes
275
 
276
  10
@@ -288,14 +270,12 @@ and those due to COVID -19 disease.
288
 
289
 
290
  New hospitalizations
291
- During the past 28 days, 5 3 (23%) countries reported data to WHO on new hospitalizations at least once (Figure 7).
 
292
  The Region of the Americas had the highest proportion of countries reporting data on new hospitalizations (1 9
293
  countries; 3 4%), followed by the European Region (15 countries; 25%), the African Region (12 countries; 24%), the
294
  South -East Asia Region (two countries; 20%), and the Western Pacific Region (five countries; 14%). No country in the
295
  Eastern Mediterranean Region shared1. The number of countries that consistently reported new hospitalizations
296
- for the period was 9"
297
- "%), and the Western Pacific Region (five countries; 14%). No country in the
298
- Eastern Mediterranean Region shared1. The number of countries that consistently reported new hospitalizations
299
  for the period was 9% (22 countries) (Table 2).
300
 
301
  Among the 22 countries consistently reporting new hospitalizations, 8 (36%) countries registered an increase of 20%
@@ -317,16 +297,12 @@ The highest numbers of new hospital admissions were reported from the United Sta
317
 
318
  11
319
 
320
- Table 2. Number of new hospitalization admissions reported by WHO regions, 11 December 2023 to 7 January 2024
 
321
  compared to 16 October to 13 November to 10 December 2023
322
  Region Countries reported at least once in
323
  the past 28 days Countries reported consistently in the past and
324
  previous 28 days*
325
- Number"
326
- "to 10 December 2023
327
- Region Countries reported at least once in
328
- the past 28 days Countries reported consistently in the past and
329
- previous 28 days*
330
  Number of
331
  countries
332
  (percentage)** Number of new
@@ -347,25 +323,8 @@ Pacific 5/35 (14%) 14 300 5/35 (14%) 14 300 +88%
347
  Global 53/234 (2 3%) 173 547 24/234 ( 10%) 167 646 +40%
348
 
349
  *Percent change is calculated for countries reporting consistently both in the past 28 days and the previous 28 days (compari son period).
350
- **Number of countries reported / total number of countries in the region (percentage of reporting).
351
- *** N/A represents not available or applicable .
352
-
353
-
354
-
355
-
356
-
357
-
358
-
359
-
360
-
361
-
362
-
363
-
364
-
365
-
366
-
367
- "
368
- "percentage of reporting).
369
  *** N/A represents not available or applicable .
370
 
371
 
@@ -408,10 +367,8 @@ Europe Czechia 2083 2317 -10%
408
  Europe Estonia 420 474 -11%
409
  Europe Italy 8845 13857 -36%
410
  Europe Portugal 29 57 -49%
411
- South -East Asia Indonesia 1337 149 797%"
412
- "13857 -36%
413
- Europe Portugal 29 57 -49%
414
- South -East Asia Indonesia 1337 149 797%
415
  South -East Asia Bangladesh 21 23 -9%
416
  Western Pacific Brunei Darussalam 588 161 265%
417
  Western Pacific Malaysia 9312 4137 125%
@@ -435,10 +392,8 @@ Americas (10 countries, 14%), the Western Pacific Region (six countries; 17%) ,
435
  country; 10%). No country in the Eastern Mediterranean Region reported ICU data during the period. The
436
  proportion of coun tries that consistently reported new ICU admissions for the period was 8% (1 8 countries).
437
  Among the 1 8 countries consistently reporting new ICU admissions, eight ( 44%) countries showed an increase of
438
- "
439
- "new ICU admissions for the period was 8% (1 8 countries).
440
- Among the 1 8 countries consistently reporting new ICU admissions, eight ( 44%) countries showed an increase of
441
- 20% or greater in new ICU admissions during the past 28 days compared to the previous 28 -day period: Indonesia
442
  (164 vs 18; +811%), Malaysia (135 vs 15; +800%), Singapore (77 vs38; +103%), Estonia (18 vs 10; +80%), Ireland (20
443
  vs 13; +54%), Netherlands (120 vs 86; +40%), Greece (120 vs 88; +36%), and Czechia (18 2 vs 146; +25%)
444
  The highest numbers of new ICU admissions were reported from Italy (464 vs 492; -6%), Czechia (182 vs 146;
@@ -460,12 +415,11 @@ new ICU
460
  admissions Percent change in
461
  new ICU admissions
462
  Africa 13/50 (26%) 6 1/50 ( 2%) 0 N/A
463
- Americas 10/56 (1 8%) 386 2/56 (16%) 99 -"
464
- "6%) 6 1/50 ( 2%) 0 N/A
465
  Americas 10/56 (1 8%) 386 2/56 (16%) 99 -55%
466
  Eastern
467
  Mediterranean 0/22 (<1%) N/A*** 0/22 (<1%) N/A N/A
468
- Europe 12/61 (20%) 1097 8/61 (1 3%) 1032 +3%
 
469
  South -East
470
  Asia 1/10 (10%) 164 1/10 (10%) 164 +811%
471
  Western
@@ -486,19 +440,14 @@ past 28 days New ICU admissions in
486
  previous 28 days % Change in ICU
487
  admissions from
488
  previous 28 -day period
489
- A"
490
- "U admissions in
491
- past 28 days New ICU admissions in
492
- previous 28 days % Change in ICU
493
- admissions from
494
- previous 28 -day period
495
  Africa Mauritania 0 0 N/A
496
  Americas Canada 99 221 -55%
497
  Americas Honduras 0 0 N/A
498
  Europe Italy 464 492 -6%
499
  Europe Czechia 182 146 25%
500
  Europe Netherlands 120 86 40%
501
- Europe Greece 120 88 36%
 
502
  Europe Sweden 101 158 -36%
503
  Europe Ireland 20 13 54%
504
  Europe Estonia 18 10 80%
@@ -524,8 +473,6 @@ admissions (“zero reporting”) if there are no new hospital or ICU admissions
524
 
525
  15
526
  Figure 7. 28 -day global COVID -19 new hospitalizations and ICU admissions, from 3 February 2020 to 7 January
527
- 2024 (A); and from 1 May 2023 to 7 January "
528
- "9 new hospitalizations and ICU admissions, from 3 February 2020 to 7 January
529
  2024 (A); and from 1 May 2023 to 7 January 2024 (B)
530
  A
531
 
@@ -542,7 +489,8 @@ in grey bars are only from countries reporting hospitalizations or ICU admission
542
  Severity indicators
543
 
544
  The ICU -to-hospitalization ratio and death -to-hospitalization ratio have been key indicators for understanding
545
- COVID -19 severity throughout the pandemic. The ICU -to-hospitalization ratio is used to assess the proportion of
 
546
  patients requiring ICU admission in relation to the total number of hospitalizations. The death -to-hospitalization ratio
547
  is used to assess the proportion of death s in relation to hospitalized patients.
548
 
@@ -557,10 +505,6 @@ Overall, the ICU -to-hospitalization ratio has been decreasing since the peak in
557
  dropping below 0.15 since the beginning of 2022, and around 0.05 since the start of 2023 (Figure 8) . The trend has
558
  been stable in recent wee ks. This suggests that a decreasing proportion of new hospitalizations require intensive
559
  care.
560
- "
561
- "2023 (Figure 8) . The trend has
562
- been stable in recent wee ks. This suggests that a decreasing proportion of new hospitalizations require intensive
563
- care.
564
 
565
  Similarly, the death -to-hospitalization ratio has been showing a general decline since July 2021. Since January 2023,
566
  it has remained under 0.15 , varying between 0.06 to 0.14. This is an encouraging trend indicating a lower mortality
@@ -569,7 +513,8 @@ risk among hospitalized individuals.
569
  Please n ote that the causes for these decreases cannot be directly interpreted from these data, but likely include a
570
  combination of increases in infection -derived or vaccine -derived immunity, improvements in early diagnosis and
571
  clinical care, reduced strain on hea lth systems, and other factors. It is not possible to infer a decreased intrinsic
572
- virulence amongst newer SARS -CoV-2 variants from these data.
 
573
 
574
 
575
 
@@ -609,12 +554,6 @@ reported both new hospitalizations and new ICU admissions. The d eath ratio figu
609
  and new deaths.
610
  Source : WHO COVID -19 Detailed Surveillance Dashboard
611
 
612
- 18
613
- SARS -CoV-2 variants of"
614
- "that reported both new hospitalization
615
- and new deaths.
616
- Source : WHO COVID -19 Detailed Surveillance Dashboard
617
-
618
  18
619
  SARS -CoV-2 variants of interest and variants under monitoring
620
 
@@ -626,6 +565,8 @@ collection dates, so the number of submissions in a given time period may change
626
 
627
  WHO is currently tracking several SARS -CoV-2 variants, including:
628
  • Five variants of interest (VOIs): XBB.1.5, XBB.1.16, EG.5, BA.2.86 and JN.1
 
 
629
  • Five variants under monitoring (VUMs): DV.7, XBB, XBB.1.9.1, XBB.1.9.2 and XBB.2.3
630
 
631
  Table 6 shows the number of countries reporting VOIs and VUMs, and their prevalence from epidemiological week
@@ -634,8 +575,6 @@ exhibiting increasing trends are highlighted i n yellow, those that have remaine
634
  those with decreasing trends are highlighted in green.
635
 
636
  Globally, JN.1 is currently the dominant circulating VOI (reported by 71 countries), accounting for 65.5% of sequences
637
- in week 52 compared to 24.8% in week 48 (Figure"
638
- "dominant circulating VOI (reported by 71 countries), accounting for 65.5% of sequences
639
  in week 52 compared to 24.8% in week 48 (Figure 10, Table 6). Its parent lineage, BA.2.86, is stable and accounted
640
  for 7.8% of sequences in week 52 compared to 7.0% in week 48 (Figure 10, Table 6 ). The initial risk evaluation for
641
  JN.1 was published on 19 December 2023, with an overall evaluation of low public health risk at the global level
@@ -644,7 +583,8 @@ based on available evidence.
644
  The other VOIs, XBB.1.5, XBB.1.16 and EG.5, have decreased in global prevalence during the same period: XBB.1.5
645
  accounted for 3.3% of sequences in week 52, a decrease from 8.3% in week 48; XBB.1.6 accounted for 1.5% of
646
  sequences in week 52, a decrease from 6.3% in week 48; EG.5 accounted for 16.6% of sequences in week 52, a
647
- decrease from 43.6% in week 48 (Figure 10, Table 6).
 
648
 
649
  All VUMs have shown a decreasing trend over the reporting period (Table 6).
650
 
@@ -652,8 +592,6 @@ Sufficient sequencing data to calculate variant prevalence at the regional level
652
  from four WHO regions: the Region of the Americas, the Western Pacific Region, the South -East Asia Region, and the
653
  European Region (Table 7). Among the VOIs, JN.1 was the most reported variant and showing an increasing trend in
654
  all the four regions. Except for XBB.1.16 that showed a small increase in the Western Pacific Region, the other VOIs
655
- and all the VUMs in all four regions observed dec reasing or stable trends. "
656
- "regions. Except for XBB.1.16 that showed a small increase in the Western Pacific Region, the other VOIs
657
  and all the VUMs in all four regions observed dec reasing or stable trends.
658
 
659
  With declining rates of testing and sequencing globally (Figure 10), it is increasingly challenging to estimate the
@@ -680,6 +618,9 @@ adequately assessing the variant landscape.
680
  * Includes descendant lineages, except those individually specified elsewhere in the table. For example, XBB* does not includ e
681
  XBB.1.5, XBB.1.16, EG.5, XBB.1.9.1, XBB.1.9.2, and XBB.2.3.
682
 
 
 
 
683
 
684
  Table 7. Weekly prevalence of SARS -CoV-2 VOIs and VUMs by WHO regions, week 48 to week 52 of 2023
685
 
@@ -687,8 +628,6 @@ Table 7. Weekly prevalence of SARS -CoV-2 VOIs and VUMs by WHO regions, week 48
687
 
688
  * Includes descendant lineages, except those individually specified elsewhere in the table. For example, XBB* does not includ e
689
  XBB.1.5, XBB.1.16, EG.5, XBB.1.9.1, XBB.1.9.2, and XBB.2.3.
690
- ¥ due to the small numbers of sequences submitted"
691
- "XBB.1.16, EG.5, XBB.1.9.1, XBB.1.9.2, and XBB.2.3.
692
  ¥ due to the small numbers of sequences submitted in these regions, it has not been possible to determine trends for the VOIs and
693
  VUMs in these regions; this is also represented by the shaded cells in the table .
694
 
@@ -733,22 +672,14 @@ November to 3 December 2023
733
 
734
 
735
  Figure 10. Panel A shows the number, and Panel B the percentage, of all circulating variants since July to December 2023. The variants
736
- shown here include descendent lineages, except for the descendent lineage(s) listed here. The Unassigned category includes lineages
 
737
  pending for a PANGO lineage name designation, whereas the Other category includes lineages that are assigned but not listed here.
738
  Source: SARS -CoV-2 sequence data and metadata from GISAID, from 3 July to 31 December 2023.
739
 
740
 
741
 
742
 
743
- A
744
- B
745
- 22
746
- Additional"
747
- "V-2 sequence data and metadata from GISAID, from 3 July to 31 December 2023.
748
-
749
-
750
-
751
-
752
  A
753
  B
754
  22
@@ -768,9 +699,8 @@ Data for 11 December 2023 to 7 January 2024
768
  African Region
769
  The African Region reported over 3354 new cases, a 63% decrease as compared to the previous 28 -day period. Five (10%) of the 50 countries for which data are
770
  available reported increases in new cases of 20% or greater, with the highest proportional increases observed in Mauritania ( 30 vs six new cases; +400%), Senegal
771
- (17 vs six new cases ; +183%), Mali (two vs one new case; +100%), Burundi (78 vs 51 new cases; +53%), and Angola (417 vs 316 new cases; +32%). The highest
772
- numbers of new cases were reported from Mauritius (3228 new cases; 253.8 new cases per 100 000; -57%"
773
- "; +32%). The highest
774
  numbers of new cases were reported from Mauritius (3228 new cases; 253.8 new cases per 100 000; -57%), Angola (417 new cas es; 1.3 new cases per 100 000;
775
  +32%), and Burundi (78 new cases; <1 new case per 100 000; +53%).
776
  The number of new 28 -day deaths in the Region decreased by 113% as compared to the previous 28 -day period, with no new deaths reported. The highest numbers
@@ -784,8 +714,8 @@ The Region of the Americas reported over 42 000 new cases, an 18% decrease as co
784
  which data are available reported increases in new cases of 20% or greater, with the highest proportio nal increases observed in Panama (822 vs 180 new cases;
785
  +357%), Barbados (33 vs 14 new cases; +136%), Plurinational State of Bolivia (1563 vs 670 new cases; +133%), Guyana (six vs three new cases; +100%), Colombia
786
  (1 680 vs 1 266 new cases; +33%), Paraguay (92 vs 73 new cases; +26%), and Jamaica (32 vs 26 new cases; +23%). The highest numbers of new cases were reported
787
- from Canada (18 947 new cases; 50.2 new cases per "
788
- "), and Jamaica (32 vs 26 new cases; +23%). The highest numbers of new cases were reported
789
  from Canada (18 947 new cases; 50.2 new cases per 100 000; -18%), Chile (9693 new cases; 50.7 new cases per 100 000; -25%), and Peru (4657 new cases; 14.1
790
  new cases per 100 000; -38%).
791
  The number of new 28 -day deaths in the Region decreased by 41% as compared to the previous 28 -day period, with 3869 new deaths reported. The highest
@@ -801,9 +731,9 @@ Updates from the Region of the Americas
801
  The Eastern Mediterranean Region reported over 2464 new cases, a 13% decrease as compared to the previous 28 -day period. One (5%) of the 22 countries for
802
  which data are available reported increases in new cases of 20% or greater, with the highest proportional increases observed in Kuwait (102 vs 39 new cases;
803
  +162%). The highest numbers of new cases were reported from Afghanistan (1256 new cas es; 3.2 new cases per 100 000; +14%), the Islamic Republic of Iran (663
804
- new cases; <1 new case per 100 000; -48%), and Morocco (443 new cases; 1.2 new cases per"
805
- "ic Republic of Iran (663
806
  new cases; <1 new case per 100 000; -48%), and Morocco (443 new cases; 1.2 new cases per 100 000; +6%).
 
 
807
  The number of new 28 -day deaths in the Region decreased by 53% as compared to the previous 28 -day period, with 37 new deaths reported. The highest numbers
808
  of new deaths were reported from the Islamic Republic of Iran (27 new deaths; <1 new death per 100 00 0; -63%), Afghanistan (8 new deaths; <1 new death per
809
  100 000; +60%), and Morocco (2 new deaths; <1 new death per 100 000; +100%).
@@ -818,9 +748,9 @@ Updates from the Eastern Mediterranean Region
818
  The European Region reported over 701 000 new cases, a 13% decrease as compared to the previous 28 -day period. 10 (16%) of the 62 countries for which data
819
  are available reported increases in new cases of 20% or greater, with the highest proportional increases observed in Malta (310 vs 75 new cases; +313%), Republic
820
  of Moldova (2 951 vs 1 485 new cases; +99%), Ireland (3 433 vs 1 856 new cases; +85%), Greece (68 590 vs 37 925 new cases; +81%), the United Kingdom (37 787 vs
821
- 22 791 new cases; +66%), Romania (7 380 vs 4 916 new cases; +50%), Portugal (4 451 vs 3 103 new cases; +43%), Belgium (10 653 vs 8 623 new cases"
822
- "16 new cases; +50%), Portugal (4 451 vs 3 103 new cases; +43%), Belgium (10 653 vs 8 623 new cases; +24%),
823
- Luxembourg (2 054 vs 1 696 new cases; +21%), and Netherlands (5 330 vs 4 442 new cases; +20%). The highest numbers of new cases were reported from the
824
  Russian Federation (235 198 new cases; 161.2 new cases per 100 000; -30%), Italy (163 599 new cases; 274.3 new cases per 100 000; -18%), and Greece (68 590
825
  new cases; 639.9 new c ases per 100 000; +81%).
826
  The number of new 28 -day deaths in the Region decreased by 3% as compared to the previous 28 -day period, with 4194 new deaths reported. The highest numbers
@@ -835,10 +765,10 @@ Updates from the European Region
835
  25
836
  South -East Asia Region
837
  The South -East Asia Region reported over 26 000 new cases, a 379% increase as compared to the previous 28 -day period. Five (45%) of the 11 countries for which
838
- data are available reported increases in new cases of 20% or greater, with the highest proportion al increases observed in India (15 07"
839
- "-day period. Five (45%) of the 11 countries for which
840
  data are available reported increases in new cases of 20% or greater, with the highest proportion al increases observed in India (15 079 vs 1 599 new cases; +843%),
841
  Myanmar (110 vs 20 new cases; +450%), Indonesia (8 610 vs 1 727 new cases; +399%), Bangladesh (276 vs 141 new cases; +96%), and Sri Lanka (67 vs 42 new
 
 
842
  cases; +60%). The highest numbers of new cases were reported from India (15 079 new cases; 1.1 new cases per 100 000; +843%), Indonesia (8610 new cases; 3.1
843
  new cas es per 100 000; +399%), and Thailand (2327 new cases; 3.3 new cases per 100 000; +17%).
844
  The number of new 28 -day deaths in the Region increased by 564% as compared to the previous 28 -day period, with 186 new deaths reported. The highest
@@ -852,17 +782,14 @@ Updates from the South -East Asia Region
852
  26
853
  Western Pacific Region
854
  The Western Pacific Region reported over 338 000 new cases, a 77% increase as compared to the previous 28 -day period. Ten (29%) of the 35 countries for which
855
- data are available reported increases in new cases of "
856
- "000 new cases, a 77% increase as compared to the previous 28 -day period. Ten (29%) of the 35 countries for which
857
  data are available reported increases in new cases of 20% or greater, with the highest proportional increases observed in Niu e (98 vs six new cases; +1533%), Palau
858
  (16 vs two new cases; +700%), Tonga (62 vs 12 new cases ; +417%), Cook Islands (29 vs six new cases; +383%), Cambodia (76 vs 16 new cases; +375%), Brunei
859
- Darussalam (16 648 vs 4 207 new cases; +296%), Malaysia (67 206 vs 25 484 new cases; +164%), the Philippines (10 262 vs 4 672 new cases; +120%), Singapore
 
860
  (174 643 vs 80 296 new cases; +117%), and China (2 514 vs 1 674 new cases; +50%). The highest numbers of new cases were repor ted from Singapore (174 643
861
  new cases; 2985.2 new cases per 100 000; +117%), Malaysia (67 206 new cases; 207.6 new cases per 100 000; +164%), and Australia (41 965 new cases; 164.6
862
  new cases per 100 000; -18%).
863
  The number of new 28 -day deaths in the Region decreased by 45% as compared to the previous 28 -day period, with 416 new deaths reported. The highest numbers
864
- of new deaths were reported from Australia (185 new deaths; <1 new death per 100 000; -67%), Malaysi a (97 new"
865
- "s reported. The highest numbers
866
  of new deaths were reported from Australia (185 new deaths; <1 new death per 100 000; -67%), Malaysi a (97 new deaths; <1 new death per 100 000; +259%),
867
  and New Zealand (54 new deaths; 1.1 new deaths per 100 000; -49%).
868
 
@@ -874,6 +801,8 @@ Updates from the Western Pacific Region
874
  Data presented are based on official laboratory -confirmed COVID -19 cases and deaths reported to WHO by
875
  coun try/territories/areas, largely based upon WHO case definitions and surveillance guidance . While steps are taken to
876
  ensure accuracy and reliability, all data are subject to continuous verification and change, and caution must be taken when
 
 
877
  interpreting these data as several factors influence the counts presented, with variable underestimation o f true case and
878
  death incidences, and variable delays to reflecting these data at the global level. Case detection, inclusion criteria, testi ng
879
  strategies, reporting practices, and data cut -off and lag times differ between countries/territories/areas. Dif ferences are
@@ -883,8 +812,6 @@ countries of interest, time period, and purpose of the request/intended usage. P
883
  see covid19.who.int for the most up -to-date data.
884
  ‘Countries’ may refer to countries, territories, areas or other jurisdictions of similar status. The designations employed,
885
  and the presentation of these materials , do not imply the expression of any opinion whatsoever on the part of WHO
886
- concerning the legal status of any country, territory, or area or of its authorities, or concerning the delimitation"
887
- "presentation of these materials , do not imply the expression of any opinion whatsoever on the part of WHO
888
  concerning the legal status of any country, territory, or area or of its authorities, or concerning the delimitation of its
889
  frontiers or boundaries. Dotted and dashed lines on maps r epresent approximate border lines for which there may not
890
  yet be full agreement. Countries, territories, and areas are arranged under the administering WHO region. The mention
@@ -916,16 +843,4 @@ proprietary products are distinguished by initial capital letters.
916
  26
917
  Annex 2. SARS -CoV-2 variants assessment and classification
918
 
919
- WHO, in collaboration with national authorities, institutions and researchers, routinely assesses if variants of SARS -
920
- CoV-2 alter transmission or disease characteristics, or impact the effectiveness of vaccines, therapeutics, diagnostics
921
- or public health a nd social measures (PHSM) applied to control disease spread. Potential variants of concern (VOCs),
922
- variants of interest (VOIs) or variants under monitoring (VUMs) are regularly assessed based on the risk posed to
923
- global public health.
924
-
925
- The classifications of variants will be revised as needed to reflect the continuous evolution of circulating variants and
926
- their changing epidemiology. Criteria for variant classification, and the lists of currently circulating and previously
927
- circulating VO Cs, VOIs and VUMs, are available on the WHO Tracking SARS -CoV-2 variants website . National
928
- authorities may choose to designate other variants and are strongly encouraged to investigate and report newly
929
- emerging variants and their impact.
930
-
931
- WHO continues to monitor SARS -Co"
 
27
  2024.
28
  • During the 28 -day period from 11 December 2023 to 7 January , 53 and 42 countries provided data at least
29
  once on COVID -19"
30
+ "at least
 
31
  once on COVID -19 hospitalizations and admissions to an intensive care unit (ICU) , respectively . From the
32
  available data, over 173 000 new hospitalizations and over 1900 new ICU admissions were reported during
33
  the 28 -day period . Amongst the countries reporting these data consistently over the current and past
 
41
  five VOIs – XBB.1.5, XBB.1.16 , EG.5 BA.2.86 and JN.1 ; and five VUMs : DV.7, XBB, XBB.1.9.1, XBB .1.9.2 and
42
  XBB.2.3
43
  • The Global WHO Coronavirus (COVID -19) Dashboard has been updated and adapted with a new interface
 
 
44
  on 22 December 2023 to support WHO and Member States’ work to transition from COVID -19 as an
45
+ emergency to longer -term disease management, as outlined in WHO’s 3 May 2023 COVID -19 2023"
46
+ "3 COVID -19 2023 -2025
47
  Updated Strategic Preparedness and Response Plan . The new dashboard will progressively incorporate more
48
  components throughout 2024. The previous link of the Global WHO Coronavirus (COVID -19) Dashboard will
49
  still be active and redirect users to the new one from 22 December onward. Please note that start time of
 
68
 
69
  Data as of 7 January 2024
70
  Globally, the number of new weekly cases remained stable during the 28 -day period of 11 December 2023 to 7
 
 
 
71
  January 2024 as compared to the previous 28 -day period, with over 1.1 million new cases reported (Figure 1,
72
  Table 1). The number of new weekly deaths decreased by 26% as compared to the previous 28 -day period, with
73
+ 8700 new fatalities"
74
+ "
75
  8700 new fatalities reported. As of 7 January 2024, over 774 million confirmed cases and over 7 million deaths
76
  have been reported globally. According to estimates obtained from viral loads in wastewater surveillance, clinical
77
  detection of cases underestimated the real burden 2 to 19 -fold1,2,3
 
85
  deaths – the latter of which are considered more reliable indicators given reductions in testing. Global and
86
  national data on SARS -CoV-2 PCR percent positivity are available on WHO’s integrated influenza and other
87
  respiratory viruses surveillance dashboard . Recent data (epidemiological week one, 1 to 7 January 2024) from
 
 
 
88
  sentinel sites show that the SARS -CoV-2 PCR percent positivity from reporting countries averages approximately
89
  8% (Figure 2).
90
  As many countries discontinue COVID -19-specific reporting and integrate it into respiratory disease surveillance,
91
  WHO will use all available sources to continue monitoring the COVID -19 epidemiological situation, especially
92
  data on morbidity and impact on h ealth systems. COVID -19 remains a major threat, and WHO urges Member
93
+ States to maintain, not dism"
94
+ "
95
  States to maintain, not dismantle, their established COVID -19 infrastructure. It is crucial to sustain, inter alia ,
96
  early warning, surveillance and reporting, variant tracking, early clin ical care provision, administration of vaccine
97
  to high -risk groups, improvements in ventilation, and regular communication.
 
109
  countries.
110
 
111
 
 
 
 
 
112
  Figure 1. COVID -19 cases and global deaths by 28 -day intervals reported by WHO Region, as of 7 January 2024 ( A); 26
113
  June to 17 January 2024 (B)**
114
 
 
122
  At the regional level, the number of newly reported 28 -day cases decreased across four of the six WHO regions:
123
  the African Region ( -63%), the Region of the Americas ( -18%), the Eastern Mediterranean Region ( -13%), and
124
  the European Region ( -13%); while case numbers increased in two WHO regions: the Western Pacific Region
125
+ (+77%), and the South -East"
126
+ "77%), and the South -East Asia Region (+379%). The number of newly reported 28 -day deaths decreased or
127
  remained stable across five regions: the African Region ( -113%), the Eastern Mediterra nean Region ( -53%), the
128
  Western Pacific Region ( -45%), the Region of the Americas ( -41%), and the European Region ( -3%); while death
129
  numbers increased in the South -East Asia Region (+564%).
 
131
  198 new cases; -30%), Singapore (174 643 new cases; +117%), Italy (163 599 new cases; -18%), Greece (68 590
132
  new cases; +81%), and Malaysia (67 206 n ew cases; +164%). The highest numbers of new 28 -day deaths were
133
  reported from Italy (1016 new deaths; -21%), the Russian Federation (679 new deaths; +45%), Poland (543 new
 
 
134
  deaths; +229%), Sweden (446 new deaths; -47%), and Greece (322 new deaths; +79%).
135
 
136
  Table 1. Newly reported and cumulative COVID -19 confirmed cases and deaths, by WHO Region, as of 7 January 2024**
 
153
  reporting
154
  deaths in
155
  the last 28
156
+ "
157
+ "in
158
+ the last 28
159
  days
160
  Europe 701 053
161
  (63%) -13% 278 615
 
175
  (49%) 8/35
176
  (23%)
177
  America
 
 
 
 
 
 
178
  s 42 330
179
  (4%) -18% 193 223
180
  732
 
198
  (0%) -113% 175 473
199
  (3%) 28/50
200
  (56%) 4/50
201
+ (8%)"
202
+ " 4/50
203
  (8%)
204
  Eastern
205
  Mediter
 
219
  (45%) 51/234
220
  (22%)
221
 
 
 
 
 
 
 
222
  *Percent change in the number of newly confirmed cases/deaths in the past 28 days, compared to 28 days prior. Data from previous weeks are
223
  updated continuously with adjustments received from countries.
224
  **See Annex 1: Data, table, and figure notes
 
240
  **See Annex 1: Data, table, and figure notes
241
 
242
  7
243
+ Figure 4. Percentage change in confirmed COVID -19 cases over the last 2"
244
+ "-19 cases over the last 28 days relative to the previous 28 days, as of 7 January 2024**
245
 
246
  **Se e Annex 1: Data, table, and figure notes
247
 
 
253
  9
254
  Figure 6. Percentage change in confirmed COVID -19 deaths over the last 28 days relative to the previous 28 days, as of 7 January 2024**
255
 
 
 
 
256
  **Se e Annex 1: Data, table, and figure notes
257
 
258
  10
 
270
 
271
 
272
  New hospitalizations
273
+ During the past 28 days, 5 3 (23%) countries reported data to WHO on new hospitalizations at least once (Figure 7)."
274
+ "izations at least once (Figure 7).
275
  The Region of the Americas had the highest proportion of countries reporting data on new hospitalizations (1 9
276
  countries; 3 4%), followed by the European Region (15 countries; 25%), the African Region (12 countries; 24%), the
277
  South -East Asia Region (two countries; 20%), and the Western Pacific Region (five countries; 14%). No country in the
278
  Eastern Mediterranean Region shared1. The number of countries that consistently reported new hospitalizations
 
 
 
279
  for the period was 9% (22 countries) (Table 2).
280
 
281
  Among the 22 countries consistently reporting new hospitalizations, 8 (36%) countries registered an increase of 20%
 
297
 
298
  11
299
 
300
+ Table 2. Number of new hospitalization admissions"
301
+ "2. Number of new hospitalization admissions reported by WHO regions, 11 December 2023 to 7 January 2024
302
  compared to 16 October to 13 November to 10 December 2023
303
  Region Countries reported at least once in
304
  the past 28 days Countries reported consistently in the past and
305
  previous 28 days*
 
 
 
 
 
306
  Number of
307
  countries
308
  (percentage)** Number of new
 
323
  Global 53/234 (2 3%) 173 547 24/234 ( 10%) 167 646 +40%
324
 
325
  *Percent change is calculated for countries reporting consistently both in the past 28 days and the previous 28 days (compari son period).
326
+ **Number of countries reported / total number of countries in the region ("
327
+ "reported / total number of countries in the region (percentage of reporting).
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
328
  *** N/A represents not available or applicable .
329
 
330
 
 
367
  Europe Estonia 420 474 -11%
368
  Europe Italy 8845 13857 -36%
369
  Europe Portugal 29 57 -49%
370
+ South -East Asia Indonesia 133"
371
+ "East Asia Indonesia 1337 149 797%
 
 
372
  South -East Asia Bangladesh 21 23 -9%
373
  Western Pacific Brunei Darussalam 588 161 265%
374
  Western Pacific Malaysia 9312 4137 125%
 
392
  country; 10%). No country in the Eastern Mediterranean Region reported ICU data during the period. The
393
  proportion of coun tries that consistently reported new ICU admissions for the period was 8% (1 8 countries).
394
  Among the 1 8 countries consistently reporting new ICU admissions, eight ( 44%) countries showed an increase of
395
+ 20% or greater in new ICU admissions during the past 28 days compared to the previous 28 -day period: Indones"
396
+ "the previous 28 -day period: Indonesia
 
 
397
  (164 vs 18; +811%), Malaysia (135 vs 15; +800%), Singapore (77 vs38; +103%), Estonia (18 vs 10; +80%), Ireland (20
398
  vs 13; +54%), Netherlands (120 vs 86; +40%), Greece (120 vs 88; +36%), and Czechia (18 2 vs 146; +25%)
399
  The highest numbers of new ICU admissions were reported from Italy (464 vs 492; -6%), Czechia (182 vs 146;
 
415
  admissions Percent change in
416
  new ICU admissions
417
  Africa 13/50 (26%) 6 1/50 ( 2%) 0 N/A
 
 
418
  Americas 10/56 (1 8%) 386 2/56 (16%) 99 -55%
419
  Eastern
420
  Mediterranean 0/22 (<1%) N/A*** 0/22 (<1%) N/A N/A
421
+ Europe 12/61 (20%) 1097 8/61 (1 3"
422
+ "7 8/61 (1 3%) 1032 +3%
423
  South -East
424
  Asia 1/10 (10%) 164 1/10 (10%) 164 +811%
425
  Western
 
440
  previous 28 days % Change in ICU
441
  admissions from
442
  previous 28 -day period
 
 
 
 
 
 
443
  Africa Mauritania 0 0 N/A
444
  Americas Canada 99 221 -55%
445
  Americas Honduras 0 0 N/A
446
  Europe Italy 464 492 -6%
447
  Europe Czechia 182 146 25%
448
  Europe Netherlands 120 86 40%
449
+ Europe Greece 120 88 36%"
450
+ "120 88 36%
451
  Europe Sweden 101 158 -36%
452
  Europe Ireland 20 13 54%
453
  Europe Estonia 18 10 80%
 
473
 
474
  15
475
  Figure 7. 28 -day global COVID -19 new hospitalizations and ICU admissions, from 3 February 2020 to 7 January
 
 
476
  2024 (A); and from 1 May 2023 to 7 January 2024 (B)
477
  A
478
 
 
489
  Severity indicators
490
 
491
  The ICU -to-hospitalization ratio and death -to-hospitalization ratio have been key indicators for understanding
492
+ COVID -19 severity throughout the pandemic. The ICU -to-hospitalization ratio is used"
493
+ "U -to-hospitalization ratio is used to assess the proportion of
494
  patients requiring ICU admission in relation to the total number of hospitalizations. The death -to-hospitalization ratio
495
  is used to assess the proportion of death s in relation to hospitalized patients.
496
 
 
505
  dropping below 0.15 since the beginning of 2022, and around 0.05 since the start of 2023 (Figure 8) . The trend has
506
  been stable in recent wee ks. This suggests that a decreasing proportion of new hospitalizations require intensive
507
  care.
 
 
 
 
508
 
509
  Similarly, the death -to-hospitalization ratio has been showing a general decline since July 2021. Since January 2023,
510
  it has remained under 0.15 , varying between 0.06 to 0.14. This is an encouraging trend indicating a lower mortality
 
513
  Please n ote that the causes for these decreases cannot be directly interpreted from these data, but likely include a
514
  combination of increases in infection -derived or vaccine -derived immunity, improvements in early diagnosis and
515
  clinical care, reduced strain on hea lth systems, and other factors. It is not possible to infer a decreased intrinsic
516
+ virulence amongst newer SARS -CoV-2 variants"
517
+ "newer SARS -CoV-2 variants from these data.
518
 
519
 
520
 
 
554
  and new deaths.
555
  Source : WHO COVID -19 Detailed Surveillance Dashboard
556
 
 
 
 
 
 
 
557
  18
558
  SARS -CoV-2 variants of interest and variants under monitoring
559
 
 
565
 
566
  WHO is currently tracking several SARS -CoV-2 variants, including:
567
  • Five variants of interest (VOIs): XBB.1.5, XBB.1.16, EG.5, BA.2.86 and JN.1
568
+ • Five variants under monitoring (V"
569
+ "
570
  • Five variants under monitoring (VUMs): DV.7, XBB, XBB.1.9.1, XBB.1.9.2 and XBB.2.3
571
 
572
  Table 6 shows the number of countries reporting VOIs and VUMs, and their prevalence from epidemiological week
 
575
  those with decreasing trends are highlighted in green.
576
 
577
  Globally, JN.1 is currently the dominant circulating VOI (reported by 71 countries), accounting for 65.5% of sequences
 
 
578
  in week 52 compared to 24.8% in week 48 (Figure 10, Table 6). Its parent lineage, BA.2.86, is stable and accounted
579
  for 7.8% of sequences in week 52 compared to 7.0% in week 48 (Figure 10, Table 6 ). The initial risk evaluation for
580
  JN.1 was published on 19 December 2023, with an overall evaluation of low public health risk at the global level
 
583
  The other VOIs, XBB.1.5, XBB.1.16 and EG.5, have decreased in global prevalence during the same period: XBB.1.5
584
  accounted for 3.3% of sequences in week 52, a decrease from 8.3% in week 48; XBB.1.6 accounted for 1.5% of
585
  sequences in week 52, a decrease from 6.3% in week 48; EG.5 accounted for 16.6% of sequences in week 52, a
586
+ decrease from 43.6% in week 48 (Fig"
587
+ ".6% in week 48 (Figure 10, Table 6).
588
 
589
  All VUMs have shown a decreasing trend over the reporting period (Table 6).
590
 
 
592
  from four WHO regions: the Region of the Americas, the Western Pacific Region, the South -East Asia Region, and the
593
  European Region (Table 7). Among the VOIs, JN.1 was the most reported variant and showing an increasing trend in
594
  all the four regions. Except for XBB.1.16 that showed a small increase in the Western Pacific Region, the other VOIs
 
 
595
  and all the VUMs in all four regions observed dec reasing or stable trends.
596
 
597
  With declining rates of testing and sequencing globally (Figure 10), it is increasingly challenging to estimate the
 
618
  * Includes descendant lineages, except those individually specified elsewhere in the table. For example, XBB* does not includ e
619
  XBB.1.5, XBB.1.16, EG.5, XBB.1.9.1, XBB.1.9.2, and XBB.2.3.
620
 
621
+ "
622
+ ".2.3.
623
+
624
 
625
  Table 7. Weekly prevalence of SARS -CoV-2 VOIs and VUMs by WHO regions, week 48 to week 52 of 2023
626
 
 
628
 
629
  * Includes descendant lineages, except those individually specified elsewhere in the table. For example, XBB* does not includ e
630
  XBB.1.5, XBB.1.16, EG.5, XBB.1.9.1, XBB.1.9.2, and XBB.2.3.
 
 
631
  ¥ due to the small numbers of sequences submitted in these regions, it has not been possible to determine trends for the VOIs and
632
  VUMs in these regions; this is also represented by the shaded cells in the table .
633
 
 
672
 
673
 
674
  Figure 10. Panel A shows the number, and Panel B the percentage, of all circulating variants since July to December 2023. The variants
675
+ shown here include descendent lineages, except for the descendent lineage(s)"
676
+ "except for the descendent lineage(s) listed here. The Unassigned category includes lineages
677
  pending for a PANGO lineage name designation, whereas the Other category includes lineages that are assigned but not listed here.
678
  Source: SARS -CoV-2 sequence data and metadata from GISAID, from 3 July to 31 December 2023.
679
 
680
 
681
 
682
 
 
 
 
 
 
 
 
 
 
683
  A
684
  B
685
  22
 
699
  African Region
700
  The African Region reported over 3354 new cases, a 63% decrease as compared to the previous 28 -day period. Five (10%) of the 50 countries for which data are
701
  available reported increases in new cases of 20% or greater, with the highest proportional increases observed in Mauritania ( 30 vs six new cases; +400%), Senegal
702
+ (17 vs six new cases ; +183%), Mali (two vs one new case; +100%), Burundi (78 vs 51 new cases; +53%), and Angola ("
703
+ "; +53%), and Angola (417 vs 316 new cases; +32%). The highest
 
704
  numbers of new cases were reported from Mauritius (3228 new cases; 253.8 new cases per 100 000; -57%), Angola (417 new cas es; 1.3 new cases per 100 000;
705
  +32%), and Burundi (78 new cases; <1 new case per 100 000; +53%).
706
  The number of new 28 -day deaths in the Region decreased by 113% as compared to the previous 28 -day period, with no new deaths reported. The highest numbers
 
714
  which data are available reported increases in new cases of 20% or greater, with the highest proportio nal increases observed in Panama (822 vs 180 new cases;
715
  +357%), Barbados (33 vs 14 new cases; +136%), Plurinational State of Bolivia (1563 vs 670 new cases; +133%), Guyana (six vs three new cases; +100%), Colombia
716
  (1 680 vs 1 266 new cases; +33%), Paraguay (92 vs 73 new cases; +26%), and Jamaica (32 vs 26 new cases; +23%). The highest numbers of new cases were reported
717
+ from"
718
+ "highest numbers of new cases were reported
719
  from Canada (18 947 new cases; 50.2 new cases per 100 000; -18%), Chile (9693 new cases; 50.7 new cases per 100 000; -25%), and Peru (4657 new cases; 14.1
720
  new cases per 100 000; -38%).
721
  The number of new 28 -day deaths in the Region decreased by 41% as compared to the previous 28 -day period, with 3869 new deaths reported. The highest
 
731
  The Eastern Mediterranean Region reported over 2464 new cases, a 13% decrease as compared to the previous 28 -day period. One (5%) of the 22 countries for
732
  which data are available reported increases in new cases of 20% or greater, with the highest proportional increases observed in Kuwait (102 vs 39 new cases;
733
  +162%). The highest numbers of new cases were reported from Afghanistan (1256 new cas es; 3.2 new cases per 100 000; +14%), the Islamic Republic of Iran (663
 
 
734
  new cases; <1 new case per 100 000; -48%), and Morocco (443 new cases; 1.2 new cases per 100 000; +6%).
735
+ The number of new 2"
736
+ "6%).
737
  The number of new 28 -day deaths in the Region decreased by 53% as compared to the previous 28 -day period, with 37 new deaths reported. The highest numbers
738
  of new deaths were reported from the Islamic Republic of Iran (27 new deaths; <1 new death per 100 00 0; -63%), Afghanistan (8 new deaths; <1 new death per
739
  100 000; +60%), and Morocco (2 new deaths; <1 new death per 100 000; +100%).
 
748
  The European Region reported over 701 000 new cases, a 13% decrease as compared to the previous 28 -day period. 10 (16%) of the 62 countries for which data
749
  are available reported increases in new cases of 20% or greater, with the highest proportional increases observed in Malta (310 vs 75 new cases; +313%), Republic
750
  of Moldova (2 951 vs 1 485 new cases; +99%), Ireland (3 433 vs 1 856 new cases; +85%), Greece (68 590 vs 37 925 new cases; +81%), the United Kingdom (37 787 vs
751
+ 22 791 new cases; +66%), Romania (7 380 vs 4 916 new cases; +50%), Portugal (4 451 vs 3 103 new cases; +43%), Belgium (10 653 vs 8 623 new cases; +24%),
752
+ Luxembourg (2 054 vs 1 696 new cases; +21%), and Netherlands (5 330 vs 4 442 new cases; +20%). The highest numbers of new"
753
+ "; +20%). The highest numbers of new cases were reported from the
754
  Russian Federation (235 198 new cases; 161.2 new cases per 100 000; -30%), Italy (163 599 new cases; 274.3 new cases per 100 000; -18%), and Greece (68 590
755
  new cases; 639.9 new c ases per 100 000; +81%).
756
  The number of new 28 -day deaths in the Region decreased by 3% as compared to the previous 28 -day period, with 4194 new deaths reported. The highest numbers
 
765
  25
766
  South -East Asia Region
767
  The South -East Asia Region reported over 26 000 new cases, a 379% increase as compared to the previous 28 -day period. Five (45%) of the 11 countries for which
 
 
768
  data are available reported increases in new cases of 20% or greater, with the highest proportion al increases observed in India (15 079 vs 1 599 new cases; +843%),
769
  Myanmar (110 vs 20 new cases; +450%), Indonesia (8 610 vs 1 727 new cases; +399%), Bangladesh (276 vs 141 new cases; +96%), and Sri Lanka (67 vs 42 new
770
+ cases; +"
771
+ "vs 42 new
772
  cases; +60%). The highest numbers of new cases were reported from India (15 079 new cases; 1.1 new cases per 100 000; +843%), Indonesia (8610 new cases; 3.1
773
  new cas es per 100 000; +399%), and Thailand (2327 new cases; 3.3 new cases per 100 000; +17%).
774
  The number of new 28 -day deaths in the Region increased by 564% as compared to the previous 28 -day period, with 186 new deaths reported. The highest
 
782
  26
783
  Western Pacific Region
784
  The Western Pacific Region reported over 338 000 new cases, a 77% increase as compared to the previous 28 -day period. Ten (29%) of the 35 countries for which
 
 
785
  data are available reported increases in new cases of 20% or greater, with the highest proportional increases observed in Niu e (98 vs six new cases; +1533%), Palau
786
  (16 vs two new cases; +700%), Tonga (62 vs 12 new cases ; +417%), Cook Islands (29 vs six new cases; +383%), Cambodia (76 vs 16 new cases; +375%), Brunei
787
+ Darussalam (16 648 vs 4 207 new cases; +296%), Malaysia (67"
788
+ "296%), Malaysia (67 206 vs 25 484 new cases; +164%), the Philippines (10 262 vs 4 672 new cases; +120%), Singapore
789
  (174 643 vs 80 296 new cases; +117%), and China (2 514 vs 1 674 new cases; +50%). The highest numbers of new cases were repor ted from Singapore (174 643
790
  new cases; 2985.2 new cases per 100 000; +117%), Malaysia (67 206 new cases; 207.6 new cases per 100 000; +164%), and Australia (41 965 new cases; 164.6
791
  new cases per 100 000; -18%).
792
  The number of new 28 -day deaths in the Region decreased by 45% as compared to the previous 28 -day period, with 416 new deaths reported. The highest numbers
 
 
793
  of new deaths were reported from Australia (185 new deaths; <1 new death per 100 000; -67%), Malaysi a (97 new deaths; <1 new death per 100 000; +259%),
794
  and New Zealand (54 new deaths; 1.1 new deaths per 100 000; -49%).
795
 
 
801
  Data presented are based on official laboratory -confirmed COVID -19 cases and deaths reported to WHO by
802
  coun try/territories/areas, largely based upon WHO case definitions and surveillance guidance . While steps are taken to
803
  ensure accuracy and reliability, all data are subject to continuous verification and change, and caution must be taken when
804
+ interpreting these"
805
+ "must be taken when
806
  interpreting these data as several factors influence the counts presented, with variable underestimation o f true case and
807
  death incidences, and variable delays to reflecting these data at the global level. Case detection, inclusion criteria, testi ng
808
  strategies, reporting practices, and data cut -off and lag times differ between countries/territories/areas. Dif ferences are
 
812
  see covid19.who.int for the most up -to-date data.
813
  ‘Countries’ may refer to countries, territories, areas or other jurisdictions of similar status. The designations employed,
814
  and the presentation of these materials , do not imply the expression of any opinion whatsoever on the part of WHO
 
 
815
  concerning the legal status of any country, territory, or area or of its authorities, or concerning the delimitation of its
816
  frontiers or boundaries. Dotted and dashed lines on maps r epresent approximate border lines for which there may not
817
  yet be full agreement. Countries, territories, and areas are arranged under the administering WHO region. The mention
 
843
  26
844
  Annex 2. SARS -CoV-2 variants assessment and classification
845
 
846
+ WHO, in collaboration with national authorities, institutions and researchers, routinely assesses if variants of S"