"Took byetta for a number of years and started getting sugar "crashes" around 1 to 2 hrs after injecting so had to sugar up to counteract which was rather non productive.  There was some fear that I would go low for a week when first starting but that didn't happen.  Very stable A1c @ 6.25 like a rock for years.  Do not eat full size meals or you can experience pretty nasty nausea when your stomach won't empty and the meal "ferments".  I don't call the shot the core drill for nothing.  Bleeding should be expected and the time release makes nodules which can work out through the skin surface with a small red bump which lasts up to two weeks.  I keep a small led flashlight to eyeball (shine through)  the pen ."