Lithium
bipolar disorde
"After almost dying of chronic alcoholism I was diagnosed with bipolar disorder and put on lithium in May 2006 (currently on 750 mg per day). I was also taking Seroquel and Imipramine.  I put on 50 lbs and my wife kept commenting on how I was listless and "zoned out".  This was a big problem because I write fiction for a living, which requires energy and alertness.  With my doctor I started tweaking the Seroquel and Imipramine and finally quit them altogether (the info sheets for both state they "may result in weight gain"). The weight is melting off, I'm off the booze and feel great.  Life hasn't been this good in a long time."