Pramipexole
restless legs syndrome
"I've dealt with 10+ years of restless legs and arms to the point I'd be in tears and have actually fallen out of my king sized bed.  After trials of numerous medications (Ambien, Lunesta, leviteracetam, tranquilizers, mega vitamins) and months of little to no sleep I went begging for help to my GP.  i was desperate at that point.  With nothing else to try he sent me to a neurologist who specialized in sleep disorders and RLS.  She started me on melatonin 1 mg at 6 pm, 5 mg at sleep along with pramipexole 0.25 mg in late afternoon if needed and 0.5 mg at 9 PM. WOW. Within one week I was getting far more sleep than I've seen in at least 2 years."