Aspirin
pain
"This would be the second most effective NSAID for me, behind Motrin but well ahead of Aleve or other OTC's of any type - It is my preference for "cold and flu" because it breaks a fever pretty quick.   If there is a downside, it's that if I take 2 or 3 a day for more than a week, it definitely causes a ringing in my ears, loud.   Short-term or simple pain, the old school aspirin just works."