Venlafaxine
depression
"It’s now six months since my psychiatrist switched me to 150mg daily of this drug from 40mg Escitalopram, which had worked for me but quite suddenly ceased to be effective - so much so that I became intent on suicide. Instantly, I became a zombie – constantly exhausted, irritable, unable to concentrate, loss of sexual function and basically subsisting from day to day. Whilst I now felt too lethargic to even contemplate suicide, my doctor thought these side-effects were unusual and so we tried halving the dosage, but 75mg proved inadequate and just made me feel wired. Since adjusting the dosage to 112.5mg, however, I feel so much better and all of the initial side-effects have since abated, so for me, getting the dosage right was crucial."