Cyclosporine
keratoconjunctivitis sicca
"I have used Restasis for about a year now and have seen almost no progress.  For most of my life I've had red and bothersome eyes. After trying various eye drops, my doctor recommended Restasis.  He said it typically takes 3 to 6 months for it to really kick in but it never did kick in.  When I put the drops in it burns my eyes for the first 30 - 40 minutes.  I've talked with my doctor about this and he said it is normal but should go away after some time, but it hasn't. Every year around spring time my eyes get terrible irritated  and this year has been the same (maybe even worse than other years) even though I've been using Restasis for a year now. The only difference I notice was for the first couple weeks, but now I'm ready to move on."