Plaquenil
systemic lupus erythematosus
"I was eventually diagnosed with SLE in 2012, 3 months after my first (& worst) flare.  I took prednisone for a week, & started taking 200mg plaquenil & 2400mg ibuprofen daily, & 50-150mg tramadol as needed for pain.  In my experience, the prednisone helped to reduce the excruciating, debilitating joint pain by calming the inflammation, & plaqenil & ibuprofen keep it at bay...for the most part.  My rheumatologist took me off plaquenil 2 years ago; I still take 400 mg of ibuprofen 2X/week.  I still get flares once or twice a year, but they are not as bad...6, as opposed to a 10 , on the pain scale. Tinnitus started a few weeks after I started plaquenil & I still have it.  It's vastly annoying, but at least it doesn't hurt!  best of luck to all!"