Linaclotide
irritable bowel syndrome
"I tried everything. Diet, exercise, teas, fiber supplements, miralax, amitiza (rx). This is the only one that has worked immediately and effectively.  I am out of commission for two hrs after taking which has to be on an empty stomach so I'm only taking on weekends now.  No headaches, nausea, or other I'll effects like when I took amitiza or miralax.  Hope this keeps working long term"