Propranolol
migraine prevention
"Propranolol has reduced the frequency of migraines during the past 8 months that I've been on it. However, it makes me so tired and "out-of-it" that I'm lethargic...so I've put on 15 pounds and I never want to do anything! I can't stand this awful side effect. I'm 46, female, and now weigh 160. Was at 145 before propranolol. The size Large pants are getting tight. I'll be in XL soon if I stay in this medication. It doesn't help that I'm also on Lyrica since one month ago (so now I'm even MORE tired and confused!)   Tried topamax in the past to prevent migraines. It did help in my 30s, but not in my 40s."