Amitriptyline
irritable bowel syndrome
"After years of messing around with various diets, pills, etc - and getting down to 125 lbs (I'm a 51 year old male, 5'9") - Elavil has apparently cured my IBS-D.  I still avoid dairy and spicy food (also have GERD) - but basically, I'm cured.  I've also gained 25 lbs - which is actually too much.  It does seem to increase your appetite.  But - that's a trade-off I'm willing to make.  I have no idea why I wasn't given this med by my GI guy.  I was actually given it by my PCP for Anxiety, and I wanted something that wouldn't make my IBS-D worse."