Spironolactone
acne
"I've been having painful nodular cystic acne for the past 1 year. I've had polycystic ovarian syndrome for some time, but for some reason, the acne became a problem this year. So far, I have been on the spironolactone for 1 month, and I broke out AGAIN after my period as expected, but it's much less. Smaller nodules, barely noticeable, and not painful. 

I'm at a 50 mg/day dose now. Hopefully the acne should improve if I'm patient, but so far the acne is definitely less severe. 

Side effects: some weight loss, which is probably all the urine I'm peeing out as this is a diuretic; some dryness of the skin, nothing a moisturizer can't help with. 

"