Diclofenac / misoprostol
sciatica
"Arthrotec75 was prescribed after I developed serious aching in my right thigh that prevented me from standing or walking for more than a few minutes. Eventually, a herniated disc at L-4-L5 was diagnosed. A large fragment was pressing up against a nerve. After a few more weeks, the onset of motor deficit in my foot led to the need to have surgery. If that hadn't happened, I might have been able to avoid the surgery indefinitely by continuing to take Arthrotec. Other NSAIDs might have worked too, but protection of the stomach lining by Arthrotec's misoprostol was appealing."