Synvisc-One
osteoarthritis
"I've had both the cortisone shots and the Synvisc-One.  I believe they were equally painful, the Synvisc maybe slightly more, as the fluid seems to be quite a bit thicker so there was noticeably more pressure.  However, it's been well over 6 months and I haven't had any pain.  I've recommended it for my father and would recommend it if the normal cortisone shots don't seem to work any longer."