Lithium
bipolar disorde
"I have had depression forever and after failed SSRIs mania started to occur. Luckily I was already seeing a psychiatrist he tried me on Seroquel which made me way too sleepy and then Lithium which stopped both mania and depression. Although it doesn't cure bipolar so I still have manic and depressive episodes during stressful times but they are much more minor now I'm on Lithium. Only side effects are tremors for me but they are fairly minor."