Methotrexate
psoriasis
"Age 59, F, living N W Eire. No history of psoriasis until it struck 2 yrs ago. Small plaques on scalp, left elbow, then palms of hands, fingers & soles of feet. Itchy, shredding skin, burning as if stung by nettles. Open, painful cracks. Emollients, lotions, prescription creams had no effect. Water & detergents irritated. Touch & walking agony. Latex gloves for shower/chores, cotton gloves at work. Dermatologist found 'debilitating stage 2 psoriatic arthritis' prescribed 2.5 Methotrexate x6 once wkly plus Folic Acid and bloods checked wkly. Now 7th week. Plus: using hands &  walking, no irritation. Neg: tired, poor focus, urinary infections, worse in bad weather, still avoiding water/detergents. Conclusion: Highly recommend Methotrexate"