Are there some nice properties for a finite two-player game having an increasing differences utility and a decreasing differences utility? Nice properties of the set of Nash equilibria can be shown for supermodular games(see here). But for a two-player game in which 


Strategy spaces for two player, $S_1$ and $S_2$ are finite, and both of them are subsets of $\mathbb R$.
$u_1$ exhibits increasing differences while $u_2$ exhibits decreasing differences.


What can we say about it?
There is a recent paper which may help you:
Games with strategic complements and substitutes (Monaco and Sabarwal (2015))