Is extraterrestrial mining more difficult or impractical for bodies without plate tectonics? This article talks about the possibility of mining Uranium on the moon. Since the Moon lacks the geological forces that have created veins of concentrated minerals on Earth, would extraterrestrial mining be more difficult or impractical? How does Moon, Martian, or asteroid mining overcome the lack of mineral veins otherwise formed by Earth's geology? 

It seems like extraterrestrial mining would be at least as difficult as trying to refine desert sand, which isn't a thing.

A short video on how gold veins form

Wayfaring Stranger added an interesting link on ore genesis.
I vaguely remember my dad talking about this. 

Uranium and other heavy elements are dense. When the celestial body was molten (early in it's life) all the heavy elements sank to the core of the body. Now, with tectonics, the heavy elements are brought back up to the surface. This is why we can mine Uranium on Earth near the surface: the Uranium was brought back up due to convention current on Earth.
In conclusion, it's not worth it at all to mine on a non-tectonically active planet/moon

If anyone can extend this, please do.