What is the largest hydrogen-burning star? I am wondering what is the largest known core hydrogen-burning star?  A look at the list of largest known stars on Wikipedia seems to indicate VV Cephei B (at the bottom of the list), but I would like to know for sure if it is the largest known.  In addition to knowing which star it is, I would also like to know its temperature, size, and expected lifetime.

I am also curious to know if the largest known core hydrogen-burning star is similar to what astrophysicists theorize is the largest possible core hydrogen-burning star (given current metallicity conditions in the universe; I know star-formation timescales have a metallicity dependence) and the expected temperature, size, and lifetime of such an object.
I assume by largest, you mean largest radius.

Well it won't be VV Cep B since this is merely a B-type main sequence star.

O-type main sequence stars are known and these have both larger masses and larger radii on the main sequence (when they are burning hydrogen in their cores).

A selection of the most massive objects can be found in the R136 star forming region in the Large Magellanic Clouds. If you look at this list (though I recommend having a look at the primary literature), you will see that O3V stars are listed. Such objects are also present in our Galaxy, for instance in the supercluster NGC 3603 (Crowther &amp; Dessart 1998).

Such stars have masses of maybe $100 M_{\odot}$, luminosities of $2\times 10^{6} L_{\odot}$ and temperatures of 50,000 K. Using Stefan's law, we can deduce radii of $\sim 20 R_{\odot}$.

There are suggestions that even more massive main sequence stars have existed in R136 and NGC 3603 (see Crowther et al. 2010), which are now seen as evolved Wolf-Rayet objects, possibly up to $300 M_{\odot}$ on the main sequence (though this is a model-dependent extrapolation), and these would have had radii $&gt;20 R_{\odot}$.

In the very early universe, population III main sequence stars without metals could have been much more massive and larger.