Can a change in the density of interstellar and intergalactic quantum fields affect the Redshift of photons? Using our solar system's heliosphere as an analagy to what is happening in our galaxy and even the universe as a whole, can light redshift with changes in quantum fields? 

The universe is constantly being bombarded by particles from stars, pulsars, quasars, black holes, etc..    Is it possible for these particles to interact with photons in a way that will cause light to redshift?
No.

Or at least such an effect has never been observed, neither in the locality of the Earth or in light detected from distant sources.

If a photon has an interaction with a quantum field (such as an electromagnetic field) this causes a scattering. Scattering would cause a blurring and dimming of distant sources. This is not observed. 

Such an effect, if it existed, should also be present on more local scales. But there is no redshift related to distance within our galaxy. Nor is there any evidence of any shift, even tiny, in the photons emitted by other local sources

Thus such a proposal would require an unknown interaction of light, that causes no scattering, only affects light from outside the local group of galaxies, but is otherwise linear with distance. And one would have to explain such phenomena as the slowing of time in distant galaxies, (which an expanding universe model understands as the relativistic time dilation)

So in short: No, a change in the density of interstellar and intergalactic quantum fields does not cause the observed red-shift of photons.