Directions to Proxima Centauri I'm writing a sci-fi novel in which humans venture to the stars for the first time. Their "shake down" cruise takes them to Proxima Centauri. I'm trying to understand where Proxima Centauri is located relative to the sun rather than Earth, as that seems a more logical reference for navigation to nearby stars.

The location of Proxima Centauri in Earth's night sky is described with the Earth-relevant coordinates


  Right ascension   14h 39m 36.49400
  
  Declination –60° 50′ 02.3737


However, the Earth's orbit is inclined 7.155° to the Sun's equator and our axis is tilted at 23.4392811°.

Is there a reference indicating Proxima Centauri's sol-relative position, or can that position be calculated based on the above information?
A system of coordinates requires a fixed plane to define "zero latitude" and a direction chosen in that plane to define "zero longitude".

For directions to the stars, the distances are so great that it matters not if you base your coordinates at the Sun or at the Earth, because the distance between the Sun and Earth is so small in relation to the distances to the stars. 

There are a few coordinate systems in use.  The first uses the Earth's Equator as the fixed plane and the direction of the sun on March 21 (vernal equinox) as the direction of zero longitude. For historical reasons the longitude in this system is called Right Ascension and latitude is called Declination. It would be quite suitable for your adventurers to use.

You can also use the plane of the solar system, or the plane of the galaxy as the fixed plane. In these coordinates systems Proxima is located at

-44:45:47.62 Latitude(deg)   +239:06:53.08 Longitude(deg) Ecliptic
-01:55:37.90 Latitude(deg)   +313:56:23.96 Longitude(deg) Galactic


But remember that Proxima is moving, so these figures are not fixed.