A 40-year-old male presents with persistent muscle and joint pain, cognitive difficulties, and profound fatigue. He was diagnosed with Lyme disease a year ago and completed a course of antibiotics. What could be the diagnosis, and what is the treatment plan?
This patient's ongoing symptoms despite previous treatment for Lyme disease suggest post-treatment Lyme disease syndrome (PTLDS). This syndrome is characterized by persistent symptoms such as fatigue, musculoskeletal pain, and cognitive difficulties, which can last for more than six months after completion of antibiotic therapy. Currently, there are no proven treatments for PTLDS, but managing symptoms with physical therapy, pain management, cognitive rehabilitation, and other supportive measures is often beneficial.