A 60-year-old woman presents with abdominal pain, jaundice, and dark urine. She also reports itching all over her body. On physical examination, her liver is palpable and firm. What could be the potential diagnoses and next steps?
This patient's symptoms are suggestive of cholestatic liver disease, with potential causes including primary biliary cirrhosis, primary sclerosing cholangitis, or a blockage in the bile ducts (possibly due to gallstones or a tumor). The next steps would include liver function tests, an abdominal ultrasound to assess the biliary tract, and possibly further imaging or a liver biopsy depending on the results.