one embodiment of a syringe kit for mixing two medicinal chemicals according to the present invention will be described below referring to the attached drawings . a syringe kit for mixing two medicinal chemicals according to one embodiment is used to mix a medicinal chemical a and a medicinal chemical b when necessary , for example . as shown in fig1 , a syringe kit for mixing two medicinal chemicals according to one embodiment comprises a first barrel 2 ( see fig2 and 3 ) and a second barrel 4 ( see fig4 and 5 ), wherein a first plunger 1 is inserted into the first barrel 2 in a freely slidable manner and a medicinal chemical a is contained in the inner space in advance , and a second plunger 3 is inserted into the second barrel 4 in a freely slidable manner and a medicinal chemical b is contained in the inner space in advance . the first plunger 1 has a gasket ( not shown in drawings ) and an end plate 1 a , wherein the gasket is attached to the tip portion which faces the inner space of the first barrel 2 and the end plate 1 a is formed at the rear end portion of the first plunger 1 which protrudes from the rear end portion of the first barrel 2 . the second plunger 3 is similarly configured and the second plunger 3 has a gasket ( not shown in drawings ) at the tip portion which faces the inner space of the second barrel 4 , and an end plate 3 a is formed at the rear end portion of the second plunger 3 which protrudes from the rear end portion of the second barrel 4 . although the material constituting the first barrel 2 is not limited to a specific material , it is preferable to use a material which is generally used for syringes , which is optically transparent and which has a grass transition point or a melting point of 110 ° c . or higher , for example , polypropylene , polymethylpentene , polyolefin like cyclic polyolefin , polyethylene terephthalate , polyethylene naphthalate , amorphous polyarylate , etc . cyclic polyolefin is especially desirable in view of a high transparency , a high steam sterilization property and a good medical agent non - absorption property . the first barrel 2 is integrally formed by one of the aforementioned various types of synthetic resins using injection - molding so that a flange 2 a is formed at the rear end portion . similarly , the second barrel 4 is integrally formed by one of the aforementioned various synthetic resins using injection - molding so that a flange 4 a is formed at the rear end portion . the first barrel 2 and the second barrel 4 may be formed by either an identical synthetic resin or a similar type of synthetic resin ( hereinafter , called as a similar type of synthetic resin ) or different synthetic resins or different types of synthetic resins ( hereinafter , called as different types of synthetic resins ). here , as shown in fig2 and 3 , a connecting tube portion 2 b is formed at the tip portion of the first barrel 2 , and a male screw 2 c is formed on the outer periphery of the connecting tube portion 2 b . the male screw 2 c is constituted as a trapezoidal screw with a large lead angle and a less winding number . an inner tapered surface 2 d is formed on the inner periphery of the connecting tube portion 2 b . the inner tapered surface 2 d has a taper angle in a range between 6 % and 12 %, preferably in a range between 6 % and 10 %. in general , nozzles of commercially supplied injectors have a taper ( which corresponds to the outer tapered surface 4 e according to the present invention ) of about 6 % usually . therefore , it is preferable to set the taper angle of the inner tapered surface 2 d to 6 % because it is possible to connect a commercially supplied injector to the first barrel according to the present invention . in this case , the male screw 2 c needs to have a shape and size which is suitable to screw together with a commercially supplied injector . additionally , it is preferable to set the taper angle of the inner tapered surface 2 d to a range between 6 % and 10 % as described above because it is possible to use a commercially supplied injector and the second barrel designed according to the present invention as well . alternatively , it is effective in some applications to intentionally set the taper angle of the inner tapered surface 2 d to an angle for which a commercially supplied injector cannot be used . on the other hand , as shown in fig4 and 5 , a nozzle portion 4 c having a center hole 4 b is formed at the tip portion of the second barrel 4 , and a screw tube portion 4 d is formed at the external side of the nozzle portion 4 c in a concentric fashion . an outer tapered surface 4 e is formed on the outer periphery of the nozzle portion 4 c . the outer tapered surface 4 e has the aforementioned taper angle and fits tightly and smoothly to the inner tapered surface 2 d on the inner periphery of the connecting tube portion 2 b . a female screw 4 f is formed on the inner periphery of the screw tube portion 4 d . the female screw 4 f is screwed together with the male screw 2 c on the outer surface of the connecting tube portion 2 b in a freely removable manner . it is preferable to arrange so that the taper angle of the inner tapered surface 2 d and that of the outer tapered surface 4 e are concerted in view of a good sealing performance , however they do not need to be concerted always as described above . either one of the surface of the male screw 2 c of the connecting tube portion 2 b of the first barrel 2 and the surface of the female screw 4 f of the screw tube portion 4 d of the second barrel 4 is roughened to a predetermined surface roughness . in this embodiment , the surface of the female screw 4 f of the screw tube portion 4 d of the second barrel 4 is not roughened , whereas the surface of the male screw 2 c and the outer periphery of the connecting tube portion 2 b of the first barrel 2 shown in fig6 are roughened to a surface roughness in a range between ra1 . 0 and ra2 . 0 . additionally , it is constituted so that the tip portion of the nozzle portion 4 c of the second barrel 4 is positioned in the connection tube portion 2 b of the first barrel 1 in a condition that the inner tapered surface 2 d of the connecting tube portion 2 b of the first barrel 2 and the outer tapered surface 4 e of the nozzle portion 4 c of the second barrel 4 are in a taper - fitted condition ( see fig8 ). in a syringe kit for mixing two medicinal chemicals according to one embodiment as described above , for example , when the medicinal chemical a in the first barrel 2 is mixed with the medicinal chemical b in the second barrel 4 , the male screw 2 c on the outer periphery of the connecting tube portion 2 b of the first barrel 2 and the female screw 4 f on the inner periphery of the screw tube portion 4 d of the second barrel 4 shown in fig1 are screwed together , and the inner tapered surface 2 d on the inner periphery of the connecting tube portion 2 b of the first barrel 2 and the outer tapered surface 4 e on the outer periphery of the nozzle portion 4 c of the second barrel 4 are taper - fitted ( see fig7 ). during the operation , because either the surface of the male screw 2 c and the outer periphery of the connecting tube portion 2 b of the first barrel 2 or the surface of the female screw 4 f and the inner periphery of the screw tube portion 4 d of the second barrel 4 or both of them ( in this embodiment , the surface of the male screw 2 c of the connecting tube portion 2 b of the first barrel 2 ) is roughened to a surface roughness in a range between ra1 . 0 and ra2 . 0 , stick and slip phenomena are prevented . additionally , it is preferable in view of a secured sealing performance to roughen neither the inner tapered surface 2 d on the inner periphery of the connecting tube portion 2 b of the first barrel 2 nor the outer tapered surface 4 e of the nozzle portion 4 c of the second barrel 4 . therefore , in a syringe kit for mixing two medicinal chemicals according to one embodiment , it is possible to prevent stick and slip phenomena which tend to occur when the male screw 2 c on the outer periphery of the connecting tube portion 2 b of the first barrel 2 and the female screw 4 f on the inner periphery of the screw tube portion 4 d of the second barrel 4 are screwed together or they are released from a screwed condition , and thus it is possible to ensure a smooth and steady operation . additionally , in a syringe kit for mixing two medicinal chemicals according to one embodiment , the tip portion of the nozzle portion 4 c of the second barrel 4 is positioned in the connecting tube portion 2 b of the first barrel 2 in a condition that the inner tapered surface 2 d on the inner periphery of the connecting tube portion 2 b of the first barrel 2 and the outer tapered surface 4 e on the outer periphery of the nozzle portion 4 c of the second barrel 4 are taper - fitted ( see fig8 ). thus , in a condition that the connecting tube portion 2 b of the first barrel 2 is connected to the screw tube portion 4 d of the second barrel 4 as shown in fig7 , the gasket of the first plunger 1 of the first barrel 2 can slide in the first barrel 2 with a sufficient stroke . as a result , it is possible to sufficiently and certainly mix the medicinal chemical a in the first barrel 2 with the medicinal chemical b in the second barrel 4 . a syringe kit for mixing two medicinal chemicals according to the present invention is not limited to the aforementioned embodiment . for example , it is possible to roughen only the surface of the female screw 4 f and the inner periphery of the screw tube portion 4 d of the second barrel 4 to a surface roughness in a range between ra1 . 0 and ra2 . 0 while the surface of the male screw 2 c and the outer periphery of the connecting tube portion 2 b of the first barrel 2 are not roughened . it is also possible to roughen both the surface of the male screw 2 c and the outer periphery of the connecting tube portion 2 b of the first barrel 2 and the surface of the female screw 4 f and the inner periphery of the screw tube portion 4 d of the second barrel 4 . the most preferable embodiment is to roughen only the surface of the male screw 2 c and the outer periphery of the connecting tube portion 2 b of the first barrel 2 . this embodiment can be used as a commercially supplied injector . it is also possible to change the surface roughness for roughening within a range between ra1 . 0 and ra2 . 0 depending upon the type of synthetic resin which constitutes the first barrel 2 or the second barrel 4 . by setting the surface roughness to this range , it successfully prevent stick and slip phenomena even when the first barrel 2 and the second barrel 4 are formed by either a same type of synthetic resin or different types of synthetic resins . it is impossible to effectively prevent stick and slip phenomena by using synthetic resins which is generally used for syringes if the surface roughness is less than ra1 . 0 . the screwed connection may be loosened because of a decreased screwed connection resistance during the mixing operation if the surface roughness is higher than ra2 . 0 .
a syringe kit for mixing two medicinal fluids includes first and second barrels containing medicinal fluids therein . the first barrel includes a connecting tube portion at a tip portion having a male screw on an outer periphery , and a non - roughened inner tapered surface on an inner periphery . the second barrel includes a second plunger , a screw tube portion with a female screw on an inner periphery thereof freely engageable with the male screw of the connecting tube portion , and a nozzle portion situated inside the screw tube portion with a non - roughened outer tapered surface fitting to the non - roughened inner tapered surface . a surface of the male screw and the outer periphery of the connecting tube portion , or a surface of the female screw and the inner periphery of the screw tube portion are roughened to a surface roughness in a range between ra 1 . 0 and ra 2 . 0 micrometer .