as used herein , “ at least one ,” “ one or more ,” and “ and / or ” are open - ended expressions that are both conjunctive and disjunctive in operation . for example , each of the expressions “ at least one of a , b and c ,” “ at least one of a , b , or c ,” “ one or more of a , b , and c ,” “ one or more of a , b , or c ” and “ a , b , and / or c ” means a alone , b alone , c alone , a and b together , a and c together , b and c together , or a , b and c together . various embodiments of the present inventions are set forth in the attached figures and in the detailed description as provided herein and as embodied by the claims . it should be understood , however , that this detailed description does not contain all of the aspects and embodiments of the one or more present inventions , is not meant to be limiting or restrictive in any manner , and that the invention ( s ) as disclosed herein is / are and will be understood by those of ordinary skill in the art to encompass obvious improvements and modifications thereto . additional advantages of the present invention will become readily apparent from the following discussion , particularly when taken together with the accompanying drawings . in the following discussion , the terms “ proximal ” and “ distal ” will be used to describe the opposing axial ends of the inventive ablation device , as well as the axial ends of various component features . the term “ proximal ” is used in its conventional sense to refer to the end of the ablation device ( or component thereof ) that is closest to the operator during use of the ablation device . the term “ distal ” is used in its conventional sense to refer to the end of the ablation device ( or component thereof ) that is initially inserted into the patient , or that is closest to the patient during use . for example , an ablation device may have a proximal end and a distal end , with the proximal end designating the end closest to the operator , such as a handle , and the distal end designating an opposite end of the ablation device . similarly , the term “ proximally ” refers to a direction that is generally towards the operator along the path of the ablation device and the term “ distally ” refers to a direction that is generally away from the operator along the ablation device . fig1 illustrates an embodiment of a flexible mesh ablation device 100 in accordance with the present invention . the flexible mesh ablation device 100 includes a flexible woven mesh 102 at a distal portion 104 . the flexible woven mesh 102 is operably connected to an inner shaft 106 and an outer shaft 108 . the flexible woven mesh 102 may be secured at a proximal end 120 to a distal end 122 of the outer shaft 108 and at a distal end 124 to a distal end 126 of the inner shaft 106 . in some embodiments , the inner shaft 106 is coaxially positioned within the outer shaft 108 as shown in fig1 . the flexible woven mesh 102 expands and collapses by longitudinal movement of the inner shaft 106 relative to the outer shaft 108 as explained in more detail below . a control handle 110 is provided at a proximal portion 112 of the flexible mesh ablation device 100 . the control handle 110 is operable to control the movement of the inner shaft 106 and the outer shaft 108 relative to one another . the control handle 110 may be any type of handle that is operable to control the movement of the inner shaft 106 relative to the outer shaft 108 and need not have the structure illustrated in fig1 . as shown in fig1 , a distal portion 112 of the flexible woven mesh 102 is operably connected to the inner shaft 106 . a proximal portion 114 of the flexible woven mesh 102 is operably connected to the outer shaft 108 . relative movement between the inner shaft 106 and the outer shaft 108 causes the flexible woven mesh 102 to change between a collapsed configuration shown in fig1 , and an expanded configuration shown in fig2 . the flexible woven mesh 102 in the unexpanded configuration has a first outside diameter 116 and the flexible woven mesh 102 in the expanded configuration extends beyond the first outside diameter 116 at a middle segment 118 . the unexpanded configuration may be used to deliver the flexible mesh ablation device 100 to a treatment site within a patient and for repositioning the flexible mesh ablation device 100 within a patient &# 39 ; s lumen to provide treatment to additional sites if needed . fig2 illustrates the flexible mesh ablation device of fig1 in an expanded configuration . the outer shaft 108 has been moved distally relative to the inner shaft 106 decreasing the distance between the distal end 122 of the outer shaft 108 and the distal end 126 of the inner shaft 106 . the decrease in distance causes the flexible woven mesh 102 to expand radially as shown in fig2 . because the mesh is flexible , it will conform to the surface of the lumen in which it is deployed , including many surface irregularities . a cross - sectional view of an embodiment of the flexible woven mesh 102 is shown in fig3 and a side view of the flexible woven mesh 102 is shown in fig4 . the flexible woven mesh 102 is comprised of a plurality of nonconductive filaments 202 that are woven together to form a cylindrical sleeve 200 having a cylindrical inner surface 204 and a cylindrical outer surface 206 . in some embodiments , the nonconductive filaments 202 may be formed from a polymeric material such as a polyolefin , a fluoropolymer , a polyester , for example , polypropylene , polytetrafluoroethylene , polyvinylidene fluoride , polyethylene terephthalate ( pet ), and combinations thereof . other materials known to one skilled in the art may also be used to form the nonconductive filaments 202 , provided that they enable the flexible woven mesh 102 to be changeable from the expanded state and the unexpanded state in response to the inner shaft 106 moving relative to the outer shaft 108 . fig5 through fig9 illustrates various embodiments of a flexible woven mesh 102 suitable for use in the flexible mesh ablation device shown in fig1 . the inner shaft 106 and outer shaft 108 are not illustrated for clarity . each embodiment of the flexible woven mesh 102 will be illustrated in an unexpanded state and an expanded state . it will be generally understood that the flexible woven mesh 102 may enter the expanded state when the proximal end 120 and the distal end 124 of the flexible woven mesh 102 are brought closer together . fig5 illustrates an exemplary flexible woven mesh 500 illustrating the placement of a conductive coating 502 on at least one nonconductive filament 504 . in some embodiments , the conductive coating 502 is placed on a single filament 504 , while in other embodiments the conductive coating 502 is placed on a plurality of intermeshed filaments , as shown in fig5 . fig6 illustrates the same flexible woven mesh 500 as fig5 , but with the flexible woven mesh 500 being expanded . in this embodiment the conductive coating 502 is applied to the outer cylindrical surface of the flexible woven mesh 500 along a helical pattern of intermeshed filaments 504 to form a helical conductor . other configurations of conductive coatings are possible . for example , in embodiments in which a different ablation pattern is necessary , the conductive coating 502 could be applied in a complementary pattern , such as run parallel to the axis of the flexible woven mesh 500 or perpendicular to the axis of the flexible woven mesh 500 . the conductive coating 502 may partially circumscribe the cylindrical surface of the flexible woven mesh 500 , extend one full revolution about the axis of the flexible woven mesh 500 , or may extend more than one revolution about the axis . in some embodiments , the conductive coating 502 may span a gap between adjacent nonconductive filaments 504 . a flexible base material may be wrapped around the mesh as a base layer for the conductive coating 502 . the flexible base material may span the area between filaments 504 which may increase the amount of conductive coating 502 that can be applied . one example of a suitable flexible base material between the conductive coating 502 and the filaments 504 is silicone . the conductive coating 502 may be a conductive ink applied to the surface of the mesh . one example a conductive ink is silver ink , although other metallic inks are possible . the conductive coating 502 may comprise a conductive painting , conductive glue , or other conductive materials that form a flexible coating on the non - conductive filaments 504 . fig7 illustrates an exemplary flexible woven mesh 700 illustrating a bipolar arrangement of conductive coatings 702 , 704 . fig8 illustrates the flexible woven mesh 700 of fig7 with the flexible woven mesh 700 being expanded . a first conductive coating 702 coats a first pattern of nonconductive filaments 706 and a second conductive coating 704 coats an adjacent pattern of nonconductive filament 706 . an ablation zone 708 is formed between the first conductive 702 coating and the second conductive coating 704 . the first conductive coating 702 and the second conductive coating 704 are electrically isolated from one another such that there is no conductive path from the first conductive coating 702 to the second conductive coating 704 . this bipolar arrangement allows for a precise ablation zone 708 between the conductive coatings 702 , 704 . fig9 illustrates another embodiment of an exemplary flexible mesh 900 illustrating another pattern of conductive coatings to form a bipolar ablation device . fig1 illustrates the flexible mesh 900 of fig9 with the flexible mesh 900 expanded . in the embodiment of fig9 a first conductive coating 902 coats a proximal hemispherical portion of filaments 910 . a second conductive coating 904 coats an opposite , distal hemispherical portion of filaments 910 that are electrically insulated from the first conductive coating such that there is no conductive path from the first conductive coating 902 to the second conductive coating 904 . an ablation zone 906 is formed in a region between the first conductive coating 902 and the second conductive coating 904 . the first conductive coating 902 and the second conductive coating 904 may have a boundary 908 that follows a nonconductive filament 910 as shown in fig1 . in some embodiments the boundary of the conductive coatings may follow a path other than a nonconductive filament 910 . fig1 illustrates the proximal end of a flexible mesh ablation device 1100 . in each of the previously described embodiments , the conductive coating is operably connected to an energy source . as shown in fig1 , a handle 1102 may include a connector 1104 for operably connecting the conductive coating to an energy source 1106 . as shown , the energy source 1106 may be a radio frequency source . however , other types of energy sources may also be used to provide energy to the conductive coating . by way of non - limiting example , additional possible energy sources may include microwave and electric current . the conductive coating is connected to the power source by an electrical conductor , such as one or more wires 1108 that extend from the conductive coating to the connector 1104 that connects to the energy source 1106 . the one or more wires 1108 may extend through a lumen 1110 of the inner 1112 shaft or may extend through a lumen of the outer shaft 1114 or external to the outer shaft 1114 and may optionally include a sleeve surrounding the outer shaft 1114 and one or more wires 1108 . as discussed above , the handle 1102 is operable to move the inner shaft 1112 relative to the outer shaft 1114 so that the flexible woven mesh 1102 moves between the expanded configuration and the collapsed configuration ( see fig1 and 2 ). by way of non - limiting example , the handle 1102 includes a first portion 1116 and a second portion 1118 that move relative to each other . as shown in fig1 , the first portion 1116 is operably connected to the inner shaft 1112 . the second portion 1118 is operably connected to the outer shaft 1114 . the first portion 1116 may be moved proximally and / or the second portion 1118 may be moved distally to move the inner shaft 1112 proximally and / or the outer shaft 1114 distally to move the flexible woven mesh 102 to the expanded configuration as shown in fig2 . as shown in fig1 , the first portion 1116 may be moved distally and / or the second portion 1118 moved proximally to move the inner shaft 1112 distally and / or the outer shaft 1114 proximally to move the flexible woven mesh 102 to the collapsed configuration . the handle 1102 may include a lock 1120 shown in fig7 to releasably lock the first portion 1116 in position relative to the second portion 1118 and thus lock the flexible woven mesh 102 in position . the lock 1120 may releasably lock the first and second portions 1116 , 1118 of the handle 1102 together at any proximal / distal positioning of the inner and outer shafts 1112 , 1114 so that the flexible woven mesh 102 may be locked at any size that is suitable for the treatment site . for example , if the treatment site is in a narrow lumen , the first portion 1116 of the handle 1102 may be moved slightly in the proximal direction to give the flexible woven mesh 102 a smaller diameter than if the first portion 1116 were moved fully distally to give the flexible woven mesh 102 the largest diameter . fig1 illustrates another embodiment of a flexible mesh ablation device 1200 . the flexible mesh ablation device 1200 is comprised of a catheter 1202 , a nonconductive flexible mesh 1204 , and a sheath 1206 . the sheath 1206 is mounted about the catheter 1202 such that it may be moved between a first location ( shown in fig1 ) in which the sheath 1206 provides a radial constraint to the nonconductive flexible mesh 1204 and a second position ( shown in fig1 ) in which the sheath 1206 does not provide a radial constraint to the nonconductive flexible mesh 1204 . a conductive coating 1208 is disposed on an exterior of the nonconductive flexible mesh 1204 and is in electrical communication with a power source ( not shown ) through a conductor 1210 . the nonconductive flexible mesh 1204 is woven in an expanded configuration with an outside diameter 1212 greater than an outside diameter 1214 of the catheter 1202 . the nonconductive flexible mesh 1204 is biased to maintain the expanded configuration . a proximal end 1216 is radially compressed to have a reduced diameter complementary to the outside diameter of the catheter 1202 . the reduced diameter is secured to the catheter 1202 , maintaining the reduced diameter despite the bias of the nonconductive flexible mesh 1204 . the nonconductive flexible mesh 1204 tapers from the reduced diameter portion to the expanded diameter . as previously described , the conductive coating is applied to an outer surface of the nonconductive flexible mesh 1204 , preferable in a helical pattern . because the filaments of the nonconductive flexible mesh 1204 are typically woven in a helical pattern , the conductive coating 1208 may follow at least one filament . in the embodiment of fig1 , the conductive coating 1208 is applied to adjacent filaments and the filament segments between the adjacent filaments . a flexible base material may be applied between the nonconductive flexible mesh 1204 and the conductive coating 1208 . the nonconductive flexible mesh 1208 may be changed from the expanded state of fig1 to the radially constrained state of fig1 by advancing the sheath 1206 relative to the catheter 1202 . advancing the sheath 1206 engages the taper of the nonconductive flexible mesh 1204 providing an inward radial force to collapse the nonconductive flexible mesh 1204 . as the nonconductive flexible mesh 1204 collapses , the sheath 1206 can be advanced further , constraining the nonconductive flexible mesh 1204 and further collapsing it . the sheath 1206 may be advanced until it completely covers the nonconductive flexible mesh 1204 . in this collapsed state , the nonconductive flexible mesh 1204 may be delivered to a treatment site . the above figures and disclosure are intended to be illustrative and not exhaustive . this description will suggest many variations and alternatives to one of ordinary skill in the art . all such variations and alternatives are intended to be encompassed within the scope of the attached claims . those familiar with the art may recognize other equivalents to the specific embodiments described herein which equivalents are also intended to be encompassed by the attached claims .
a flexible mesh ablation device for ablating tissue in a body lumen . the flexible mesh ablation device includes a flexible mesh with at least one conductor on an exterior surface of the flexible mesh . when the flexible mesh is compressed axially it expands radially to contact the inner surface of the body lumen and conform to the shape of the body lumen . power is applied to the conductor ablating tissue proximate the conductor .