stanozolol is a synthetic steroid derived from dihydrotestosterone ( dht ). it is commonly sold under the name winstrol . in an injectable liquid form , the stanozolol is usually dissolved in paraben water along with benzyl alcohol and sesame oil . the stanozolol will preferably be deployed in the present composition as an injectable suspension from about 10 to about 50 mg of stanozolol per ml of suspension . other components in the stanozolol suspension may include minor amounts of propylene glycol ; sodium carboxymethylcellulose ( nacmc ), sodium chloride and the like . nandralone is most usually sold as its decanoate ester under the name deca - durabolin . less common is the phenylpropionate ester commercially available under the mark durabolin . nandralone is a white crystalline powder which forms an oily , yellow suspension when suspended in benzyl alcohol and a suitable oil such as peanut oil , grapeseed oil , sesame oil and the like . the nandralone , as an injectable suspension , is present in an amount ranging from about 100 to about 200 milligrams per ml of suspension . generally , the injection will comprise from about a 0 . 5 : 1 to about 2 . 0 : 1 weight ratio of nandralone to stanozolol , and preferably about a 1 : 1 weight ratio . the resulting injectable suspension is stable for about five ( 5 ) minutes . it is injected into the buttocks of a female . in use the suspension is administered over a period of 7 to 14 days until the pain is alleviated . generally , the injection is deployed about once a week . the medications are continued until the pain is gone , indefinitely or if pregnancy is contemplated . it is further contemplated that in lieu of an injectable composition , that the composition hereof be applied as a topical cream based upon a plo or pluronoic lecithin organo gel . as is known to those skilled in the art to which the present invention pertains , plo gels are transdermal vehicles used to administer medications through the skin . these gels can be formulated to be absorbed through the skin for immediate effects . they contain combinations of ingredients that provide quick relief without unwanted side - effects . plo gels disrupt the lipid layers of the stratum corneum without damaging the skin . this allows the medication to defuse through the stratum corneum into the dermal - epidermal blood flow . generally speaking , plos are acleas - based and ordinarily contain poloxamer 407 potassium sorbate water as an aqueous phase and an organic phase of lecithin and isopropyl palmitate in sorbate acid . typically there is a four to one aqueous to organic phase in preparing the cream . in preparing a topical cream in accordance herewith , to prepare a 30 day mixture administered as two mgs of composition per day generally , about 20 mg admixed with about mg of the gel of stanozolol per ml of suspension and 20 mg per ml of suspension of nandralone are added to the plo gel . however , greater amounts can be used . for example up to about 200 mgs of the nandralone suspension and up to about 40 mgmg of the suspension stanozolol can be prepared by mixing equal volumes of the two components into the plo gel at ambient conditions with stirring . where used , the cream is applied anywhere from daily to a little as about twice a week , as dictated by the pain . where the combination of oral ingestion of stanozolol plus the injection of nandralone , generally , 20 to 50 mg per week of stanozolol is ingested , along with an injection of nadralone in the amount of 20 mg to about 40 mg of nandralone in one ml of suspension . the nadralone is a single injection on a weekly basis . the stanozolol is taken over the week in the requisite amounts to achieve a 20 to 50 mg per week dosage of suspension or cream . it should be noted that the use of nandrolone , alone , also suppresses the fsh ( follicle stimulating hormone ) and lh ( leutinizing hormone ) release from the pituitary . the present treatment focuses on plugging up the androgen - receptor ( a - r ) receptor on the endometriotic cell walls . nandrolone has an affinity to stick tightly into the a - r ; about three times stronger than testosterone and about ten to thirty times stronger than any of the estrogens , i . e . estrone , estradiol , xeno - estrogen . when the nandrolone is in the receptor , the endometrial cells ‘ dry up .’ however potent the nandrolone is , it is diluted in the blood stream by sex hormone binding globulin ( shbg ). normal range of shbg in the female blood stream is usually about 30 - 40 nmol / l . yet , the dilution potency of shbg can increase , during pregnancy , to about 500 nmol / l . thus , a woman with an androgen producing tumor will deliver a baby unaffected because of the high shbg . therefore , to maximize the effect of nandrolone it is necessary to minimize shbg . many women , not pregnant , with or without endometriosis , can have an shbg level of over about 250 nmol / l . with the use of the presently defined dosage of shbg , the shbg should suppress to less than 30 nmol / l . otherwise , more stanozolol is used in the mixture . it should be further noted that reliance on nandrolone alone fails as the androgenic side effects ( acne , weight gain , hair growth ) are self - limiting . the utilization of the present invention has exhibited efficacy in the treatment of endometriosis .
the present invention provides a composition and method for treating endometriosis which generally , comprises a mixture of anabolic steroids and the administration of same . the first anabolic steroid used is stanozolol used in conjunction with nandralone . the composition is preferably deployed an as injectable liquid suspension . it is also possible to deploy the steroids used herein as an oral administration of the stanozolol alone with an injection of nandralone weekly or as a daily topical nandralone cream .