in the following detailed description , reference is made to the accompanying drawings which form a part hereof , and in which is shown by way of illustration specific embodiments in which the invention may be practiced . in this regard , directional terminology , such as “ top ,” “ bottom ,” “ front ,” “ back ,” “ leading ,” “ trailing ,” etc ., is used with reference to the orientation of the figure ( s ) being described . because components of the embodiments can be positioned in a number of different orientations , the directional terminology is used for purposes of illustration and is in no way limiting . it is to be understood that other embodiments may be utilized and structural or logical changes may be made without departing from the scope of the present invention . the following detailed description , therefore , is not to be taken in a limiting sense , and the scope of the present invention is defined by the appended claims . fig1 a illustrates a front view of a combination exo - endocervical sampling device 20 according to one embodiment of the present invention . combination exo - endocervical sampling device 20 includes a shaft 22 , a sampler 24 , and a combination exo - endocervical sampler 26 . as a point of reference , shaft 22 and sampling device 20 are aligned along a central axis a . central axis a is a major , or longitudinal , axis of sampling device 20 . although combination exo - endocervical sampling device 20 is not typically employed in a sterile field when cell samples are collected , one embodiment provides for combination exo - endocervical sampling device 20 to be sterilized or sterilizable . in any regard , combination exo - endocervical sampling device 20 is provided with a reduced bio - load that does not disrupt cell sampling or analysis . shaft 22 defines a first end 30 opposite a second end 32 , a transverse break line 34 between the first end 30 and the second 32 , and a textured surface 36 adjacent to break line 34 . in one embodiment , shaft 22 is integrally formed of molded plastic . suitable molded plastics for shaft 22 include thermoplastic materials in general , and medical grade polyolefins including polypropylene and polyethylene in particular . in one embodiment , shaft 22 defines a first portion 37 that extends from break line 34 to sampler 24 , and a second portion 39 that extends from break line 34 to combination exo - endocervical sampler 26 . in one embodiment , textured surface 36 is disposed on second portion 39 adjacent to break line 34 . in this regard , when shaft 22 is severed at break line 34 , sampler 24 defines a distal end of first portion 37 . in a similar manner , when shaft 22 is severed at break line 34 , combination exo - endocervical sampler 26 defines a distal end of second portion 39 . in one embodiment , break line 34 is approximately centered within textured surface 36 . in one embodiment , first portion 37 defines a length l 1 between about 5 to 7 cm , and preferably the length l 1 of first portion 37 is about 6 . 5 cm . in one embodiment , second portion 39 defines a length l 2 that is between about 16 to 20 cm , preferably about 18 cm . sampler 24 is coupled to first end 30 . in one embodiment , sampler 24 includes a cotton - tipped swab . in another embodiment , sampler 24 is a rigid spatula ( as best illustrated in fig4 ). combination exo - endocervical sampler 26 is coupled to second end 32 of shaft 22 . combination exo - endocervical sampler 26 includes a pair of opposing wings 40 , 42 that are disposed transverse to shaft 22 ( i . e ., transverse to central axis a ), and a brush 46 that extends away from the wings 40 , 42 along the central axis a of shaft 22 . the wings 40 , 42 combine to define a generally curved sampling surface 44 separate from a sampling surface area provided by brush 46 . in one embodiment , brush 46 defines a height h between about 1 to 3 cm , and preferably the height h of brush 46 is about 1 . 5 cm when sampling device 20 is employed in a pap test on a non - parous patient , and height h of brush 46 is about 2 cm when sampling device 20 is employed in a pap test for a parous patient . the sampler 24 and the combination exo - endocervical sampler 26 of the combination exo - endocervical sampling device 20 enable the simultaneous collection of cells during pap test procedures and wet prep procedures through the use of a single device 20 . as employed herein , parous means a patient who has given birth vaginally one or more times . the terms non - parous and nulli - parous mean a woman who has never given birth vaginally . pregnant means a patient carrying developing offspring within the body , and in particular within the uterus . stenotic means a constriction or narrowing of a canal and in particular , a constriction or narrowing of the cervical canal . fig1 b illustrates a right side view of combination exo - endocervical sampling device 20 according to one embodiment of the present invention . in one embodiment , at least a portion of brush 46 defines a diameter that is wider than a thickness of wing 42 . in other words , portions of brush 46 extend transverse to the central axis a and are wider than the wings 40 , 42 are thick . fig1 c illustrates a top view of exo - endocervical sampler 26 according to one embodiment of the present invention . in one embodiment , exo - endocervical sampler 26 includes rigid , molded wings 40 , 42 and a flexible brush 46 formed from looped fibers ( as best illustrated in fig2 ). wings 40 , 42 define a thickness t that is between about 1 . 5 to 5 mm , and preferably thickness t is between about 2 to 4 mm . in one embodiment , wings 40 , 42 extend transverse to the central axis a ( fig1 a ) and combine to define sampling surface 44 . wings 40 , 42 are molded from a plastic , such as thermoplastic polyolefin including polyethylene , polypropylene , polyester , nylon , or “ soft ” polymers including block co - polymers such as block co - polyesters . in general , wings 40 , 42 are molded from plastics that are fda approved for medical devices . sampling surface 44 is provided to atraumatically scrape a face portion of a cervix to collect exocervical cells . in one embodiment , sampling surface 44 includes an array of beads 60 a , 60 b , 60 c , 60 d , 60 e , 60 f that project from sampling surface 44 by between about 1 - 2 mm . in one embodiment , the array of beads 60 a , 60 b , 60 c , 60 d , 60 e , 60 f is a staggered array of alternating beads , as illustrated . as shown in the illustrated embodiment , the sampling surface 44 has a first row of first projections ( e . g ., beads in the top row in fig1 c including beads 60 b and 60 d ) with each of the first projections spaced one from a next by a gap and a second row of second projections ( e . g ., beads in the bottom row in fig1 c including beads 60 a , 60 c , 60 e , and 60 f ) with each of the second projections spaced apart and disposed in one of the gaps formed by the first row of first projections . it is to be understood that other patterns of arranging 60 a , 60 b , 60 c , 60 d , 60 e , 60 f are also acceptable , and other suitable arrangements of beads is contemplated . in addition , although beads 60 a , 60 b , 60 c , 60 d , 60 e , 60 f are illustrated as circular , other shapes and conformations of beads 60 a , 60 b , 60 c , 60 d , 60 e , 60 f are contemplated . sampling surface 44 and beads 60 a , 60 b , 60 c , 60 d , 60 e , 60 f combine to atraumatically collect , or sample , exocervical cells during a pap test procedure . fig2 illustrates a perspective , simplified view of brush 46 according to one embodiment of the present invention . in general , brush 46 is provided to atraumatically collect endocervical cell samples . brush 46 includes multiple loops of fibers 70 , only three of which are illustrated in the simplified view . it is to be understood that brush 46 includes many multiples of loops of fibers 70 . in this regard , in one embodiment the multiple loops of fibers 70 are wound in a helical fashion . in another embodiment , the multiple loops of fibers 70 are wound and uniformly spaced in a symmetric “ christmas tree ” configuration . in any regard , the loops of fibers 70 do not terminate in an end , as is commonly associated with a bristle of a bristle - styled brush . bristles of a bristle brush have the potential to damage cells as they are collected . in contrast , the endless loops of fibers 70 atraumatically collect exo - endocervical and retain the cells in a void space defined between the loops of fibers 70 . brush 46 includes a semi - rigid or rigid strand 68 , and looped fibers 70 a , 70 b , and 70 c that are coupled to strand 68 . strand 68 is generally oriented along central axis a , and looped fibers 70 a , 70 b , and 70 c generally extend transverse to strand 68 and central axis a . in one embodiment , strand 68 includes two twined or twisted strands wrapped to capture looped fibers 70 a , 70 b , and 70 c . strand 68 includes corrosion resistant metal , such as stainless steel . alternatively , strand 68 is formed from plastic materials , such as nylon or polyester . in one embodiment , each looped fiber includes a first closed end 72 opposite a second closed end 74 , and the closed ends 72 , 74 extend transverse from the central axis a . the open spaces between the closed loop ends 72 , 74 provide a first means to atraumatically collect endocervical cell samples . looped fibers 70 a , 70 b , and 70 c capture and retain cervical cell samples between loop ends 72 , 74 . in contrast to the known bristle brushes that have bristle ends ( i . e . end - on bristles ), looped fibers 70 a , 70 b , and 70 c do not have bristle ends that can potentially puncture or otherwise damage tissue . significantly , looped fibers 70 a , 70 b , and 70 c are provided with closed loop ends 72 , 74 that present a lower puncture / trauma risk to tissue when compared to end - on bristles of the known cervical brushes . fig3 a illustrates a cross - sectional view of looped fiber 70 a according to one embodiment of the present invention . in one embodiment , looped fiber 70 a defines a transverse cross - section that is tri - lobal . for example , looped fiber 70 a includes a first lobe 80 a , a second lobe 80 b , and a third lobe 80 c . in one embodiment , looped fiber 70 a defines an effective diameter d 1 of between about 50 micrometers ( microns ) to about 1 , 000 microns . diameter and effective diameter are terms that are used broadly in this specification to define the outermost planform ( or perimeter ) of an object viewed in cross - section . diameter , as used herein , is not limited to circular objects . in particular , shaped looped fibers , such as fiber 70 a , define a perimeter that is non - circular . the open area between each lobe 80 a , 80 b , 80 c defines a trough that is suitable for the atraumatic collection of cervical cells . looped fiber 70 a defines a non - circular perimeter in transverse cross - section that is configured for atraumatic collection of cervical cells in a pap test procedure . in this regard , the surfaces of looped fiber 70 a are suited to abrade portions of the endocervical canal to remove cervical cells for sampling without traumatizing the surface from which the cells are removed , and without damaging the collected cells . the cross - sectional non - circular shape of looped fibers 70 provide a second means for atraumatically collecting endocervical cell samples . suitable fibers and equipment to produce suitable fibers are available from , for example , hills , inc ., w . melbourne , fla . other suitable fibers are shaped fibers available from du pont , wilmington , del . one such suitable fiber is a mushroom - shaped bicomponent fiber identified as a 3gt fiber available from du pont - torray co ., as marketed by du pont - torray co ., ltd ., and available through du pont in wilmington , del . fig3 b illustrates a cross - sectional view of another looped fiber 70 a . in one embodiment , looped fiber 70 a is x - shaped in transverse cross - section . in another embodiment , looped fiber 70 a is cross - shaped in transverse cross - section . in this regard , x - shaped looped fiber 70 a defines an effective diameter d 2 that is between about 50 to 1 , 000 microns . the open areas illustrated between legs of the x - shaped fiber 70 a form troughs that are suitable for atraumatic collection of cervical cells in a pap test procedure , as described above . suitable materials for forming / extruding shaped looped fibers 70 include polyolefins in general and thermoplastic polymers such as nylon , or polyester in particular . fig4 illustrates a front view of another combination exo - endocervical sampling device 100 according to one embodiment of the present invention . combination exo - endocervical sampling device includes a shaft 102 , a sampler 104 , and a combination exo - endocervical sampler 106 . in general , shaft 102 and exo - endocervical sampler 106 are similar to shaft 22 and exo - endocervical sampler 26 , respectively , illustrated in fig1 a above . in one embodiment , sampler 104 includes a molded plastic spatula that defines a width s of between about 0 . 5 to 2 cm , and preferably width s is about 0 . 75 cm . in one embodiment , molded plastic spatula sampler 104 is integrally formed with shaft 102 of a molded plastic , such as , for example , polyethylene . sampler 104 is suitable for atraumatic collection of cervical cells from a face of a cervix and / or cells from a vaginal wall , for example , during a pap test procedure . fig5 a illustrates a front view of an exocervical sampling device 220 according to one embodiment of the present invention . in one embodiment , exocervical sampling device 220 is configured for cervical cell sampling of a pregnant patient and includes a shaft 222 , a sampler 224 , and an exocervical sampler 226 . in one embodiment , exocervical sampling device 220 is sterilized or sterilizable , similar to device 20 above . shaft 222 defines a first end 230 opposite a second end 232 , a transverse break line 234 between the first end 230 and the second 232 , and a textured surface 236 adjacent to break line 234 . in one embodiment , shaft 222 is integrally formed of molded plastic . suitable molded plastics for shaft 222 include thermoplastic materials in general , and medical grade plastics including polypropylene and polyethylene in particular . in one embodiment , shaft 222 defines a first portion 237 that extends from break line 234 to sampler 224 , and a second portion 239 that extends from break line 234 to combination exo - endocervical sampler 226 . in one embodiment , textured surface 236 is disposed on second portion 239 adjacent to break line 234 . in this regard , when shaft 222 is severed at break line 234 , sampler 224 defines a distal end of first portion 237 . in a similar manner , when shaft 222 is severed at break line 234 , combination exo - endocervical sampler 226 defines a distal end of second portion 239 . in another embodiment , textured surface 236 spans either side of break line 234 . in one embodiment , first portion 237 defines a length ll 1 between about 5 to 7 cm , and preferably the length ll 1 of first portion 237 is about 6 . 5 cm . in one embodiment , second portion 239 defines a length ll 2 that is between about 16 to 20 cm , preferably about 16 . 5 cm . sampler 224 is coupled to first end 230 . in one embodiment , sampler 224 is a mat of fibers , such as are provided in a cotton - tipped swab . in another embodiment , sampler 224 is a rigid spatula ( similar to spatula 104 illustrated in fig4 ). exocervical sampler 226 is coupled to second end 232 of shaft 222 . exocervical sampler 226 includes a pair of opposing wings 240 , 242 that are disposed transverse to shaft 222 ( i . e ., transverse to central axis a ) and are curved to correspond to a shape compatible with an exterior surface of the cervix . the wings 240 , 242 combine to define a sampling surface 244 . fig5 b illustrates a top view of exocervical sampler 226 according to one embodiment of the present invention . wings 240 , 242 define a thickness t 2 that is between about 1 . 5 to 5 mm , and preferably thickness t 2 is between about 2 to 4 mm . in one embodiment , wings 240 , 242 extend transverse to the central axis a ( fig1 a ) and combine to define sampling surface 244 . sampling surface 244 is provided to atraumatically scrape a face portion of a cervix of a pregnant patient to collect exocervical cells . in one embodiment , sampling surface 244 includes an array of beads 260 a , 260 b , 260 c , 260 d that project above sampling surface 244 . in one embodiment , array of beads 260 a , 260 b , 260 c , 260 d is a staggered array , although other arrangements for beads 260 a , 260 b , 260 c , 260 d are also acceptable . beads 260 a , 260 b , 260 c , 260 d are illustrated as cylinders , although other shapes are also acceptable . sampling surface 244 and beads 260 a , 260 b , 260 c , 260 d combine to atraumatically collect , or sample , exocervical cells from a face of a cervix of a pregnant patient during a pap test procedure . in one embodiment , wings 240 , 242 are molded from a plastic , such as thermoplastic polymers including polyethylene , polypropylene , polyester , nylon , or “ soft ” polymers including block co - polymers such as block co - polyesters . in general , wings 240 , 242 are molded from plastics that are fda approved for medical devices . in another embodiment , wings 240 , 242 include a lofted intertwined mat of endless fibers that form a surface that is characterized by a random collection of interconnecting fibrils , as more fully described below in fig9 a . fig6 illustrates a front view of another combination exo - endocervical sampler 326 according to one embodiment of the present invention . combination exo - endocervical sampler 326 includes a pair of opposing wings 340 , 342 that are disposed transverse to shaft 322 ( i . e ., transverse to central axis a ), and a brush 346 that extends away from the wings 340 , 342 along the central axis a of shaft 322 . the wings 340 , 342 combine to define a sampling surface 344 separate from a sampling surface area provided by brush 346 . in one embodiment , brush 346 is substantially cylindrical in shape and defines a height h 2 between about 1 to 3 cm , and preferably the height h 2 of brush 346 is about 1 . 5 cm when sampler 326 is employed in a pap test on a non - parous patient , and height h 2 of brush 346 is about 2 cm when sampler 326 is employed in a pap test for a parous patient . brush 346 includes multiple loops of fibers 370 . brush 346 includes a semi - rigid or rigid strand 368 , and looped fibers 370 that are coupled to strand 368 . strand 368 is generally oriented along central axis a , and looped fibers 370 generally extend transverse to strand 368 and central axis a . in one embodiment , strand 368 includes two twined or twisted strands wrapped to capture looped fibers 370 . strand 368 includes corrosion resistant metal , such as stainless steel . alternatively , strand 368 is formed from plastic materials , such as nylon . in one embodiment , each looped fiber includes a first closed end opposite a second closed end , and the closed ends extend transverse from the central axis a , in a manner similar to that illustrated in fig2 . fibers 370 are similar to the fibers illustrated in fig2 and 3a and 3 b . in this regard , fibers 370 are looped and can include a non - circular perimeter in transverse cross - section that is configured for atraumatic collection of cervical cells in a pap test procedure . looped fibers 370 are suited to abrade portions of the endocervical canal to remove cervical cells for sampling without traumatizing the surface from which the cells are removed . fig7 illustrates a front view of another embodiment of a combination exo - endocervical sampler 426 according to one embodiment of the present invention . combination exo - endocervical sampler 426 includes a pair of opposing wings 440 , 442 that are disposed transverse to shaft 422 ( i . e ., transverse to central axis a ), and a brush 446 that extends away from the wings 440 , 442 along the central axis a of shaft 422 . the wings 440 , 442 combine to define a sampling surface 444 separate from a sampling surface area provided by brush 446 . in one embodiment , brush 446 is substantially conical in shape and defines a height h 3 between about 1 to 3 cm , and preferably the height h 3 of brush 446 is about 1 . 5 cm when sampler 426 is employed in a pap test on a non - parous patient , and height h 3 of brush 446 is about 2 cm when sampler 426 is employed in a pap test for a parous patient . brush 446 includes multiple loops of fibers 470 wound conically in a helical fashion about a semi - rigid or rigid strand 468 . strand 468 is generally oriented along central axis a , and looped fibers 470 generally extend transverse to strand 468 and central axis a . in one embodiment , strand 468 includes two twined or twisted strands wrapped to capture looped fibers 470 . strand 468 includes corrosion resistant metal , such as stainless steel . alternatively , strand 468 is formed from plastic materials , such as nylon . in one embodiment , each looped fiber includes a first closed end opposite a second closed end , and the closed ends extend transverse from the central axis a , in a manner similar to that illustrated in fig2 . fibers 470 are similar to the fibers illustrated in fig2 and 3a and 3 b . in this regard , fibers 470 are looped and can include a non - circular perimeter in transverse cross - section that is configured for atraumatic collection of cervical cells in a pap test procedure . looped fibers 470 are suited to abrade portions of the endocervical canal to remove cervical cells for sampling without traumatizing the surface from which the cells are removed . fig8 illustrates a perspective view of a brush 546 according to one embodiment of the present invention . brush 546 is usefully employed on any one of the combination exo - endocervical samplers 26 , 106 , 326 , and 426 illustrated above . in one embodiment , brush 546 is substantially conical in shape and defines a height h 4 between about 1 to 3 cm , and preferably the height h 4 of brush 546 is about 1 . 5 cm when employed in a pap test on a non - parous patient , and height h 4 of brush 546 is about 2 cm when employed in a pap test for a parous patient . brush 546 includes a sponge 550 that defines a helical surface 552 wound about a semi - rigid or rigid strand 568 . in one embodiment , sponge 550 is an open celled absorbent sponge formed of natural or synthetic cellulose or its derivatives , or of polymers . in another embodiment , sponge 550 is a closed cell sponge form of polyurethane or the like . strand 568 is generally oriented along central axis a , and includes corrosion resistant metal , such as stainless steel . alternatively , strand 568 is formed from plastic materials , such as nylon . helical surface 552 includes helically spaced ledges 554 a , 554 b , and 554 c . helical surface 552 is suited to abrade portions of the endocervical canal to remove cervical cells for sampling without traumatizing the surface from which the cells are removed . in one embodiment , brush 546 includes a pair of opposing wings defined by helical surfaces 552 that are disposed transverse to the strand 568 , and a prominence defined by top 550 of sponge . prominence , or top 550 of sponge , extends from the wings 552 along a central axis a of the strand 568 . in this regard , the opposing wings 552 define a first sampling surface and the prominence 550 defines a second sampling surface . the sponge 550 is characterized by an absence of bristles and defines pores or a void space within the sponge 550 that is configured to capture exo - endocervical cells . fig9 a illustrates a perspective view of another combination exo - endocervical sampling device 620 according to one embodiment of the present invention . combination exo - endocervical sampling device 620 includes a shaft 622 , and a combination exo - endocervical sampler 626 extending from shaft 622 and aligned along a central longitudinal axis a . in one embodiment , a separate sampler such as a swab or a spatula is coupled to shaft 622 opposite sampler 626 in a manner similar to that illustrated in figure la ( swab ) or fig4 ( spatula ). combination exo - endocervical sampler 626 includes a pair of opposing wings 640 , 642 that are disposed transverse to shaft 622 ( i . e ., transverse to central axis a ), and a prominence 646 that extends away from the wings 640 , 642 along the central axis a of shaft 622 . the prominence 646 and wings 640 , 642 combine to define a sampling surface 644 . in one embodiment , sampling surface 644 is covered at least partially by a lofted intertwined mat 648 of looped fibers that is suitable for the collection of cells from the cervical face and / or the endocervical canal . in one embodiment , prominence 646 is substantially conical in shape and defines a height h 5 between about 1 to 3 cm , and preferably the height h 5 of prominence 646 is about 1 . 5 cm when sampler 626 is employed in a pap test on a non - parous patient , and height h 5 of prominence 646 is about 2 cm when sampler 626 is employed in a pap test for a parous patient . lofted intertwined mat 648 of fibers forms a surface that is characterized by a random collection of interconnecting fibrils . the interconnecting fibrils define open spaces between the fibrils . the fibrils and the opens spaces combine to create a “ lofty ” structure that is useful in the atraumatic collection of cervical cells in a pap test procedure . the looped fibrils may be referred to as “ endless ” fibers or fibrils , as individual fibrils forming the lofted intertwined mat 648 are formed to have no distinct “ beginning ” or “ end ” ( i . e ., the fibrils are not bristles ). the lofted intertwined mat 648 is suited to abrade portions of the endocervical canal to remove cervical cells for sampling , and the open spaces between fibrils gather / retain the cells and minimize trauma to the cells as the cells are removed from the patient . fig9 b illustrates a cross - sectional view of combination exo - endocervical sampler 626 . wings 640 , 642 and prominence 646 are covered by lofted intertwined mat 648 of fibers . in one embodiment , lofted intertwined mat 648 of fibers includes a base 650 and intertwined fibers 652 extending from base 650 . in one embodiment , lofted intertwined mat 648 of fibers is formed by extruding fibers 652 from a strand die onto a carrier web , or base 650 . in an alternative embodiment , lofted intertwined mat 648 of fibers is formed by extruding fibers 652 from a strand die onto a moving conveyor belt , where the speed of the conveyor belt is selected to enable a portion of fibers 652 to cool into a continuous polymeric base 650 , and another portion of fibers 652 becomes randomly tangled and intertwined as they cool on top of base 650 . in this manner , a single process is employed to form base 650 and intertwine fibers 652 . by an appropriate selection of fiber extrusion rate and collection speed , the mat of randomly intertwined fibers 652 will extend a distance from base 650 to provide a lofty structure . between each of the randomly intertwined fibers 652 , a void or space 653 is defined that is suited for the collection of cervical cell samples . in one embodiment , base 650 and intertwined fibers 652 are formed from a thermoplastic polymeric material . preferably , thermoplastic polymeric material is flexible , soft , and suited for medical applications . examples of suitable thermoplastic materials include polyurethane , polyolefins , and polyolefins including a soft fraction of another polymer , for example , polybutylene . in one embodiment , after forming base 650 and intertwined fiber 652 , lofted intertwined mat 648 of “ endless ” fibers is thermo - formed onto sampler 626 to cover wings 640 , 642 and prominence 646 . fig1 illustrates a cross - sectional view of combination exo - endocervical sampling device 20 employed to collect cervical cells from a cervix during a pap test according to one embodiment of the present invention . with reference to fig1 a , second portion 39 of combination exo - endocervical sampling device 20 has been severed from first portion 37 . first portion 37 including sampler 24 ( fig1 a ) is provided to permit the clinician to collect a sample of cells from a wall of vagina v . generally , sampler 24 is swabbed along walls of the vagina v to capture cells for analysis . first portion 37 having the cells collected on sampler 24 is removed from the vagina v , deposited inside a standard sized test tube , the test tube is capped , and the collected sample is sent to a laboratory for analysis . thereafter , second portion 39 is inserted into the vagina v to collect cervical cells . for example , exo - endocervical sampler 26 is placed in contact with the cervix c such that sampling surface 44 contacts exocervical surface ex and brush 46 enters the cervical os to contact endocervical surface en . textured surface 36 on shaft 22 is available to provide a gripping surface that enables a clinician , for example a clinician wearing gloves , to rotate shaft 22 . rotation of shaft 22 rotates exo - endocervical sampler 26 such that sampling surface 44 sweeps across the exocervical surface ex and brush 46 rotates within and around the endocervical surface en . in this manner , sampling surface 44 collects cells from exocervical surface ex and looped fibers 70 atraumatically abrades and collects cells from the endocervical surface en of cervix c . the exo - endocervical cells that are collected are appropriately “ smeared ” across one or more microscope plates and readied for subsequent laboratory analysis , or alternatively , deposited in a standard wet prep broth container . in one embodiment , combination exo - endocervical sampling devices described above are selected based upon a status of the patient . for example , one algorithm of use provides that the clinician determines whether the patient is pregnant , and if so selects exocervical sampling device 200 ( fig5 a ). if the patient is not pregnant , the clinician determines if the patient is nulli - parous and / or likely stenotic , and if so employs combination exo - endocervical sampling device 20 ( fig1 a ). in this regard , in the case where the patient is nulli - parous , height h of brush 46 is selected to have a height of about 1 . 5 cm . if the clinician determines that the patient is parous , the clinician selects combination exo - endocervical sampling device 20 provided with brush 46 having a height h of about 2 . 0 cm . embodiments described above permit the clinician to use one tool to collect both endocervical and exocervical cell samples during a pap test procedure . this reduces the duration of the office visit , which translates to improved clinic efficiency , and reduces the cost of the instruments used to collect the samples . the looped fibers effectively collect endocervical cell samples without traumatizing the endocervical tissue or the cells . the combination exo - endocervical sampling devices described above permit the clinician to match the device to a given cervix type and sample tissue , which after analysis and diagnosis provides vitally important information useful to the clinician in the early diagnosis of cytopathologic abnormalities and common vaginoses . although specific embodiments have been illustrated and described herein , it will be appreciated by those of ordinary skill in the art that a variety of alternate and / or equivalent implementations may be substituted for the specific embodiments shown and described without departing from the scope of the present invention . this application is intended to cover any adaptations or variations of the specific embodiments discussed herein . therefore , it is intended that this invention be limited only by the claims and the equivalents thereof
a method of simultaneously collecting exocervical and endocervical cells from a female patient , includes providing a combination exo - endocervical sampling device including a sampler having a pair of opposing wings and a prominence extending from the wings . the opposing wings include a sampling surface and the prominence includes a multiplicity of endless looped fiber pairs distributed axially along a distal end section of the prominence . each looped fiber pair includes a first loop extending transverse from the shaft and a second loop extending transverse from the shaft . the loops define a void space therebetween configured to capture exo - endocervical cells . the method includes placing the sampling device in contact with a cervix of the female patient , collecting exocervical cells with the opposing wings of the sampling device , and simultaneously collecting endocervical cells with the prominence .