the invention will next be illustrated with reference to the figures wherein the same numbers indicate similar elements in all figures such figures are intended to be illustrative rather than limiting and are included herewith to facilitate the explanation of the apparatus of the present invention . for the purposes of this disclosure , like reference numerals in the figures shall refer to like features unless otherwise indicated . depicted in the figures are various aspects of the invention . elements depicted in one figure may be combined with , or substituted for , elements depicted in another figure as desired . embodiments of the invention are directed to folding arrangements of both multiple lumen type and single lumen type balloon catheters . referring now to fig1 , there is shown a multiple balloon type catheter ( 2 ) along whose main catheter shaft ( 7 ) is an expanded side balloon structure ( 5 ). fig2 shows disposed about the inflated side balloon structure ( 5 ) and the inflated main catheter balloon ( 3 ) a bifurcated stent ( 1 ) in an expanded state . some examples of multiple lumen catheters are discussed in published us patent publication nos . us 2003 / 0163082 , us 2005 / 0015108a1 , and us 2005 / 0102019a1 and co - pending , concurrently filed , and commonly owned u . s . application having an attorney docket number of s63 . 2b - 13216 - us01 the entire disclosure of which are incorporated herein by reference in their entirety . the multiple lumen type balloon catheter ( 2 ) comprises at least two balloons . one is the main catheter balloon ( 3 ) and the other is the side branch balloon ( 6 ). the side branch balloon ( 6 ) comprises a side balloon structure ( 5 ) in fluid communication with a side inflation lumen ( 8 ). some examples of single balloon type balloon catheters are discussed in published us patent publication no . us 2004 / 0138737 a1 the entire disclosure of which is incorporated herein by reference in its entirety . in a single balloon type balloon catheter , integrated into the material of the main catheter balloon is a blister of bulge which defines the side balloon structure ( 5 ). as the main catheter balloon is inflated , its side balloon structure ( 5 ) inflates as well . referring again to fig2 it is shown that the stent ( 1 ) comprises two portions , a generally tubular main stent body ( 10 ) which defines a primary fluid lumen ( 14 ) and a side branch assembly ( 30 ) the stent ( 1 ) has an expanded and an unexpanded state . when in the expanded state , the stent ( 1 ) assumes a greater volume than when in the unexpanded state . the main stent body or main branch ( 10 ) of the bifurcated stent ( 1 ) extends about a main branch central axis ( 16 ). the main stent body ( 10 ) can be expanded by pressure applied to the inner surface of the main stent body ( 10 ) by the inflation of the main catheter balloon ( 3 ), it can be inflated by a self - expansion mechanism , or it can be expanded by some combination of the two . when the stent ( 1 ) is in the expanded state , the side branch assembly or side branch ( 30 ) forms a bifurcating side branch which defines a secondary fluid lumen ( 34 ) in fluid communication with the primary fluid lumen ( 14 ). the side branch assembly extends about a side branch axis ( 46 ). this side branch is capable of extending in a radial direction ( 31 ) out of the parent vessel and into the branch vessel . in at least one embodiment , the side branch assembly ( 30 ) comprises one or more petals ( 32 ). for purposes of this application the definition of the term “ petal ” is one or more side branch members capable of twisting , bending , pivoting or otherwise opening to define the second fluid lumen ( 34 ) by opening away from the tubular shape defined by the generally tubular structure of the outer surface of the first stent body ( 10 ). it will be appreciated by persons of ordinary skill in the art that side branch assemblies can also comprises non - petal structures . as a result , all embodiments in this application which describe petals will be understood to contemplate non - petal type side branch assemblies as well . the petals ( 32 ) can be arranged in an iris configuration when the stent ( 1 ) is unexpanded and in a crown configuration when the stent ( 1 ) is expanded . for purposes of this application the definition of the term “ iris ” is when one or more petals ( 32 ) are generally lying along the tubular shape defined by the generally tubular structure of the outer surface of the first stent body ( 10 ) and are covering at least a portion of a side branch opening ( 18 ) in the main stent body ( 10 ). for purposes of this application the definition of the term “ crown ” is when as at least one petal ( 32 ) are positioned at an oblique angle radially displaced from the tubular shape defined by the generally tubular structure of the outer surface of the first stent body ( 10 ). for the purposes of this application , the definition of the term “ oblique ” is an angle of greater than zero degrees , such as an angle of between about 1 and about 180 degrees . an oblique angle explicitly includes angles of both exactly and about 90 degrees . the petals ( 32 ) are pushed from the iris configuration into the crown configuration at least in part by pressure applied to the inner surface of the petals ( 32 ) by the inflation of the a side balloon structure ( 5 ). before expansion , when in the unexpanded state , the side balloon structure ( 5 ) is in an un - inflated configuration . when this un - inflated configuration is the result of deflation and / or the application of a generally untargeted force in the luminal ( towards the stent lumen ) direction ( 35 ) or one or more generally untargeted forces along at least a portion of the radial end ( 60 ), the luminal end ( 59 ), and / or the side length ( 58 ) of the side balloon structure ( 5 ) ( as shown in fig3 ), the un - inflated balloon assumes an irregular shape . as fig4 illustrates , simple compressive force causes the balloon folds ( 57 ) and the overall assumed shape to be randomly formed due to the inconsistent and random buckling and pleating that takes place within the balloon material . only a small portion if any of the inner surface of the radial end ( 60 a ) and the inner surface of the luminal end ( 59 a ) of the side balloon structure ( 58 ) come into direct contact with each other and are separated by material from other portions of the side balloon structure . in at least one embodiment of the invention , the side balloon structure ( 5 ) when in the unexpanded state is configured according to an organized arrangement . referring now to fig6 there is shown one such organized arrangement , the “ cup ” arrangement . when the side balloon structure ( 5 ) is in the cup arrangement , at least a portion of the inner surface of the radial end ( 60 a ) and the inner surface of the luminal end ( 59 ) are substantially flush with one another . similarly at least a portion of the inner side of the upper ends of the side lengths ( 58 a ″) and the inner side of the lower ends of the side lengths ( 58 a ′) are also substantially flush with one another . the cup arrangement is characterized by a folded interface ( 56 ) being formed between the upper and lower ends of the side balloon structure . fig9 illustrates the cup arrangement in a dual lumen type balloon catheter and fig1 illustrates the cup arrangement in a single lumen type balloon catheter . as illustrated in fig5 , in at least one embodiment , the cup arrangement is formed by the application of a compressive force in the luminal direction ( 35 ) evenly distributed along the entirety of the radial end ( 60 ) and vectored towards the luminal end ( 59 ). this force can be applied in combination with a mandrel which keeps the side lengths ( 58 ) straight and rigid . this applied force will cause a folded interface to form between that portion of the side length ( 58 ) that is pushed internal to the inner side of the lower ends of the side lengths ( 58 a ′) and that portion which remains external to the inner side of the lower ends of the side lengths ( 58 a ′). as portions of the side length ( 58 ) are pushed internal to the inner side of the lower ends of the side lengths ( 58 a ′), a lip ( 29 ) forms . in at least one embodiment the cup arrangement is formed by the application of a luminally directed ( 35 ) force focused towards the center of the radial end ( 60 ) of the side balloon structure ( 5 ). this focused force cooperates with a side directed force that pushes that portion of the upper end of the balloon material internal to the inner side of the lower ends of the side lengths ( 58 a ′) to be flush with the inner side of the lower ends of the side lengths ( 58 a ′). the side balloon structure ( 5 ) can folded while , before , or after the main stent body inflating balloon or balloon portion is inflated or collapsed . referring now to fig7 there is shown at least one embodiment of the invention where at least some of the upper ends of the side lengths ( 58 a ″ and 58 b ″) and lower ends of the side lengths ( 58 a ′ and 58 b ′) are folded according to a “ discus ” arrangement . the discus arrangement can be cooperative with a cup arrangement or independently arranged . in a discus arrangement , at least a portion of the outer surface of the upper end of the side length ( 58 a ″) is folded in such a manner that it lies flush against the outer surface of the radial end ( 60 b ). in at least one embodiment illustrated in fig7 , the discus arrangement in the side balloon structure ( 5 ) has generally organized arrangement of pleats ( 40 ) in the folded balloon material . these pleats ( 40 ) can be evenly spaced about the compressed side balloon structure ( 5 ). because those portions of the balloon material closer to the center of the side balloon structure ( 5 ) have less area for their material to be spread about , the pleats ( 40 ) are present in portions of the balloon material closer to the center of the side balloon structure ( 5 ). referring now to fig1 and 11 , it can be understood because the pleats allow for overlap of balloon material in the smaller central region of the side balloon structure ( 5 ) in the discus arrangement , they can be located at or near the lip ( 29 ) between the upper and lower ends of the side length of the side balloon structure ( 5 ). in at least one embodiment illustrated in fig1 and 15 , at least a portion of the side balloon structure ( 5 ) is in a discus arrangement where the overlapping folds of material ( 27 ) are in an inter - layered arrangement fig1 illustrates a top down view of this structure and fig1 delineates with phantom lines the covered folded segments of balloon material ( 20 ). for purposes of this application , the term inter - layered is defined as an arrangement in which one side of an object is positioned above the adjacent side of a first adjacent object and the other opposite side of the object is positioned below the adjacent side of a second adjacent object . fig1 and 15 illustrate a segment ( 20 ) of the compressed side balloon structure ( 5 ) where the portion of a first end ( 20 a ) in a first overlapping region ( 41 ′) is positioned above the material of at least one adjacent folded segment ( 20 ′) and a second end ( 20 b ) overlapping region ( 41 ′) is positioned below the material of at least one adjacent folded segment ( 20 ″). the inter - layered arrangement provides at least two advantages . first during inflation as each segment is pushed in a radial direction , each inter - layered segment radially pushes the adjacent segment reducing the overall energy needed to radially push all of the segments . secondly while inflating , the arrangements cause the segments to move in a rotational direction ( 43 ). this rotational direction ( 43 ) provides a precisely directed pushing force against the crowning side branch assembly , and by sweeping each of the petals in a different tangential direction , reduces the likelihood of petals colliding with each other when crowning . the phantom lines in fig1 shown at least one embodiment where the overlapping regions ( 41 ) become progressively smaller the further they are from the center of the side balloon structure ( 5 ). referring now to fig1 there are shown an embodiment in which the discus arrangement features a plurality of evenly spaced pleats ( 40 ). the evenly spaced pleats ( 40 ) when inflated at least partially push the petals in different direction reducing the likelihood of petal collisions . fig1 and 18 illustrate embodiments having combinations of the features of fig1 and 16 . fig1 and 18 show both one or more pleats ( 40 ) and one or more folded overlapping regions ( 41 ). in addition they show that if one segment ( 20 ) of balloon material has a highly overlapping region at one end ( 45 ″) it can also have a less overlapping region ( 45 ′) at the other end of that segment . modifying the degree of overlap at different segment ends allows for modulation in the rotational sweep and speed with which different portions of the side balloon structure ( 5 ) will attain during inflation . such modulation facilitates expansion of irregularly shaped side branch structures . the various flush and even folding arrangements impart a number of advantages to the inflation process of the side balloon structure ( 5 ). one advantage is that the folding arrangement allows for control over the sequence of the inflation of particular portions of the side balloon structure allowing forces to be applied in a desired sequence . another advantage is that they allow for the smooth and even expansion of the outer surface of the radial end ( 60 b ) as it moves radially ( 31 ) away from the luminal end ( 59 ). also , the organized unfolding that the side balloon undergoes has a predictable sweeping motion which is cooperative with the crowning motion of the petals . this predictable sweeping motion reduces or prevents shear forces which can be caused by erratic motion that accompanies the inflation induced smoothing out of erratically shaped fold lines and erratically positioned portions of the side balloon structure ( 5 ). the sweeping motion with which the organized folds and pleats unfold when expanded also reduces wasted inflation energy that would otherwise accompany untangling and untwisting erratically positioned portions of the side balloon structure ( 5 ). the organized folding designs are also repeatable and can be easily integrated into industrial production lines . in addition , the organized structures reduce the likelihood of unwanted volume producing voids occupying the side branch structure ( 5 ) reducing its overall profile . similarly , the flush and even folding arrangements when inflated allow for an increase in side balloon structure ( 5 ) volume at a uniform or predictable rate volume which reduces rapid fluctuations in the velocity of the balloon inflation which would otherwise accompany the inflation of dissimilarly folded portions . the organized arrangement also allows for application of precise pushing force to be applied by the outer surface of the radial end ( 60 b ) against the petals . this precise pushing force increases inflation efficiency by assuring that majority of the volumetric expansion can be harnessed to crown the side branch assembly . fig1 - 23 illustrate one embodiment in which the precise pushing force is applied efficiently to petals ( 32 ), other portions of the side branch assembly ( 30 ), other portions of the balloon , of any other object positioned over the side balloon structure ( 5 ) in fig1 - 23 there is shown at least one embodiment of a side balloon structure ( 5 ) having a cup and discus arrangement where the blunt unfocused radial force that the inflation of the side balloon structure ( 5 ) of fig4 would produce is replaced by an orderly , sequential , and precisely directed series of forces . when the side balloon structure ( 5 ) inflates , first the discus arrangement at least partially unfolds , after which the cup arrangement is rearranged as the balloons volume is increased . as shown in fig1 , prior to inflation , the folded side balloon structure ( 5 ) has a low cross sectional profile . although fig1 illustrates a volume void between the folded side lengths equal to the volume of the lengths it will be understood that significantly greater or lesser void volumes are contemplated by this invention . as illustrated in fig2 and temporally subsequent fig2 , when the side balloon structure ( 5 ) begins its inflation , the outer surface of the radial end ( 60 b ) bulges radially before other portions of the side balloon structure ( 5 ). as shown in fig2 and 22 , this initial bulging applies a controlled radially directed pressing force against the folded side lengths ( 58 ). the radially directed pressure pushes the side lengths in a sweeping path complimentary to the bending or twisting motions that the petals ( 32 ) will undergo as they transition from an iris to a crown configuration . in particular , because the radial bulge ( 36 ) is more luminal at its center than an its edges , the radial bulge ( 36 ) applies more pushing force against the petal summit ( 38 ) and less against the petal base ( 42 ) providing torque which is highly cooperative to the bending and twisting motion needed for successful crowning . because the folding arrangement , limits the allowed initial motions to the side lengths ( 58 ) in an outwardly directed arced path there is a greatly reduced the amount of friction , rubbing or chaffing between the petal and the unfolding side balloon structure ( 5 ). in addition , because the petals ( 32 ) begin to bend outward ( and away from majority of the mass of the side branch structure ( 5 )) at the very beginning of the inflation process , the likelihood of an erratic motion by a portion of the balloon deforming , distorting , or otherwise improperly extending the side branch assembly becomes reduced . lastly because the initial inflation process moves the petals , the petals develop outwardly directed momentum which reduces the overall energy needed to extend the petals ( 32 ). referring now to fig2 there is shown that after the discus arrangement becomes somewhat unfolded the cup arrangement then becomes unfolded as well . the radially directed ( 31 ) force described in fig1 , 20 , and 21 declines and is replaced by outward a force directed in outward directions ( 37 ) parallel to axes extending from the center of the side opening ( 18 ) to the main stent body ( 10 ). this gradual replacement of the radially directed force with the outwardly directed force is complimentary to the direction vector of the petals as they gradually transition from a substantially iris configuration to a substantially crowned configuration . because as the petals become more crowned the petal tips ( 38 ) arc from a primarily radial trajectory ( 31 of fig2 ) to a primarily outward trajectory ( 37 ) the sequence of inflation matches the motion of the petals resulting in highly efficient inflation system . referring now to fig1 , in at least one embodiment , to facilitate the inflation properties of the side balloon structure ( 5 ), the radial side ( 60 ) is thinner than ( 60 ) the side length ( 58 ). by folding the side balloon structure ( 60 ) into discus arrangements , the thicker of the materials abuts the side branch assembly ( 30 ) reducing the likelihood that a portion of balloon will be ruptured or otherwise damaged by impacting against the side branch assembly ( 30 ). referring now to fig2 and 25 there is shown the main catheter balloon ( 3 ) and the side balloon structure ( 5 ). the main catheter balloon ( 3 ) and the side balloon structure ( 5 ) are in fluid communication which allows the main catheter balloon ( 3 ) and the side balloon structure ( 5 ) to undergo common inflation and deflation . fig2 illustrates a balloon catheter ( 2 ) in the unexpanded state and fig2 in the expanded state these figures also show inflation lumens at the distal and proximal sides of the side balloon structure ( 5 ) which can apply inflating fluid to different portions of the folded side balloon structure ( 5 ). embodiments contemplated by this invention include catheters in which the main catheter balloon ( 3 ) and the side balloon structure ( 5 ) are linked to different fluid sources which allows them to undergo independent inflation and deflation . similarly two or more inflation lumens can be positioned at locations about the side balloon structure ( 5 ). these inflation lumens need not only be distal to or proximal to the side balloon structure and can be positioned above , below , or at any position around the side balloon structure ( 5 ). depending on the desired sequences of inflation , the catheter may be configured so that each inflation lumen can be independently filled . alternatively the inflation lumens may be configured to be in common fluidic communication with one or more of the other inflation lumens . in addition one or more inflation lumens may be independent to provide for the withdrawal of fluid from the side balloon structure ( 5 ) or may utilize valves to only allow fluid to pass once a desired pressure level is present within the side balloon structure ( 5 ) and / or within the inflation lumen . coordination of the order of inflation , inflation pressure , fluid flux , and fluid flow directions can be combined with the other inflation embodiments disclosed in this application to facilitate the efficient and successful inflation of the side balloon structure ( 5 ). in at least one embodiment , at least one of one or more fluid lumens are positioned directly against or immediately adjacent to one or more balloon portions including but not limited to : a lip , a folded segment , a pleat , a radial end , a luminal end , a side length , a inner side of a side length , an outer side of a side length , an upper end of a side of a side length , a lower end of a side length , or any combination thereof to facilitate its displacement prior to the displacement by inflation fluid of another second portion of the side balloon structure ( 5 ). sequential displacement can be accomplished by the sequential flow of fluid through a number of specifically positioned lumens against specific side balloon structure portions . such coordinated inflation can cause or cooperatively facilitate rotationally directed movement and momentum within the inflating side balloon structure ( 5 ). in some embodiments the stent , its delivery system , or other portion of an assembly may include one or more areas , bands , coatings , members , etc . that are detectable by imaging modalities such as x - ray , mri , ultrasound , etc . in some embodiments at least a portion of the stent and / or adjacent assembly is at least partially radiopaque . in some embodiments at least a portion of the stent is configured to include one or more mechanisms for the delivery of a therapeutic agent . often the agent will be in the form of a coating or other layer ( or layers ) of material placed on a surface region of the stent , which is adapted to be released at the site of the stent &# 39 ; s implantation or areas adjacent thereto . the therapeutic agent can be at least one or various types of therapeutic agents including but not limited to : at least one restenosis inhibiting agent that comprises drug , polymer and bio - engineered materials or any combination thereof . in addition , the coating can be a therapeutic agent such as at least one drug , or at least one other pharmaceutical product such as non - genetic agents , genetic agents , cellular material , etc . some examples of suitable non - genetic therapeutic agents include but are not limited to : at least one anti - thrombogenic agents such as heparin , hepatin derivatives , vasculai cell growth promoters , growth factor inhibitors , paclitaxel , etc . where an agent includes a genetic therapeutic agent , such a genetic agent may include but is not limited to : dna , rna and their respective derivatives and / or components ; hedgehog proteins , etc . where a therapeutic agent includes cellular material , the cellular material may include but is not limited to : cells of human origin and / or non - human origin as well as their respective components and / or derivatives thereof . where the therapeutic agent includes a polymer agent , the polymer agent may be a polystyrene - polyisobutylene - polystyrene triblock copolymer ( sibs ), polyethylene oxide , silicone rubber and / or any other suitable substrate . it will be appreciated that other types of coating substances , well known to those skilled in the art , can be applied to the stent ( 1 ) as well . this completes the description of the preferred and alternate embodiments of the invention . the above disclosure is intended to be illustrative and not exhaustive . this description will suggest many variations and alternatives to one of ordinary skill in this art . the various elements shown in the individual figures and described above may be combined , substituted , or modified for combination as desired . all these alternatives and variations are intended to be included within the scope of the claims where the term “ comprising ” means “ including , but not limited to ”. further , the particular features presented in the dependent claims can be combined with each other in other manners within the scope of the invention such that the invention should be recognized as also specifically directed to other embodiments having any other possible combination of the features of the dependent claims . for instance , for purposes of claim publication , any dependent claim which follows should be taken as alternatively written in a multiple dependent form from all prior claims which possess all antecedents referenced in such dependent claim if such multiple dependent format is an accepted format within the jurisdiction ( e . g . each claim depending directly from claim 1 should be alternatively taken as depending from all previous claims ). in jurisdictions where multiple dependent claim formats are restricted , the following dependent claims should each be also taken as alternatively written in each singly dependent claim format which creates a dependency from a prior antecedent - possessing claim other than the specific claim listed in such dependent claims below .
a balloon fold design for efficient expansion of a side branch assembly in a bifurcated stent . the design involves forming a cup allangement by folding the radial end of the side branch balloon structure into the luminal end of the side branch balloon structure and then folding the cup down into an orderly discus arrangement . the folding pattern allows for the side branch balloon structure to inflate in a sweeping rotational manner efficiently pushing the side branch assembly petals out and away from the main body of the stent with a low risk of the balloon becoming entangled or damaged by its contact with the petals . the design also allows for the expansion force to be applied at the appropriate time in the optimally needed direction by initially being oriented in a predominantly circumferential direction which is gradually shifting to a predominantly radial direction . in addition , the fold design reduces the overall volume and profile of the side branch balloon structure .