referring to the drawings in particular , fig1 shows a schematic view of a mamillary three - compartment model with a central compartment 1 , two peripheral compartments 2 , 3 and an effect compartment e . the drug is administered exclusively into the central compartment 1 , and the elimination takes place exclusively from the central compartment 1 . there is no explicit mass transport into the effect compartment e , arrow drawn in broken line , k 1 e . the concentration ratio between the central compartment 1 and the effect compartment e is indicated by ke 0 . the concentration in the effect compartment e is correlated with the action independently in time . a data processing means 6 is provided in the anesthesia device according to the present invention . as is shown in fig3 , the data processing means 6 comprises a module 10 for pharmacokinetic compartment model calculations , which is set up to perform corresponding compartment model calculations for the different anesthetics of interest on the basis of the continuously entering rates of administration of the individual anesthetics . as a result , a continuously updated sequence of concentration values is provided for the anesthetics of interest , which reflect the course of anesthesia through the sequences of concentration values of the individual anesthetics . provisions are made for the module 10 for pharmacokinetic compartment model calculations to be also used to calculate concentration values for each anesthetic for one point in time or for a plurality of points in time , making the assumption that the administration of the anesthetics is continued constantly . the module 10 for the compartment model calculations may be embodied either in a separate arithmetic unit or implemented as a program section of the data processing means 6 . furthermore , a so - called action module 20 , which keeps ready the curve of at least one anesthesia action parameter as a function of the concentrations of the first and second anesthetics , is provided in the data processing means . such an anesthesia action parameter may be , e . g ., the probability of tolerance of laryngoscopy ( tol ) and that of the tolerance to shaking and shouting ( toss ). another anesthesia action parameter may be “ mac awake ” which is known as the minimum alveolar concentration ( mac ) of inhaled anesthetics that suppresses the appropriate response to command in 50 % of subjects . this dependence of the anesthesia action parameters on the concentrations of two anesthetics used can be represented in a three - dimensional system of coordinates , in which the x and y axes show the concentration of the first and second anesthetic , respectively , the respective anesthesia action parameter being shown on the x axis . examples of two such so - called response surfaces are shown in fig2 , namely , the response surfaces for the probability of the tolerance of laryngoscopy ( tol ) and the tolerance to shaking and shouting ( toss ) for the anesthetics propofol and remifentanyl . such response surfaces are obtained by statistical analyses on volunteers and on patients . the response surface can also be adapted over time in a patient specific manner . the response surfaces can be parametrized and stored in the parametrized form ; as an alternative , it is possible to store a plurality of isoboles , i . e ., lines of equal action , which are formed on cutting the response surfaces with a plane that is parallel to the x - y plane , and which can likewise characterize the course of the response surface if they are available in a sufficient number . furthermore , the data processing means 6 is provided with a display module 30 . the display module 30 receives the concentration data from the module 10 for pharmacokinetic compartment model calculation as well as data from the action module 20 , which characterize the response surface . the display module 30 is set up to actuate a display means 8 , so that at least one action diagram will be displayed on it . the concentrations of the first and second anesthetics are plotted on the x and y axes in this action diagram . the sequence of concentration values up to the current point in time is represented in this x - y system of coordinates as a sequence of dots , which represents the course of the anesthesia . furthermore , the display module 30 superimposes to the x - y system of coordinates a view of the response surface of a selected anesthetic action parameter . this superimposition can be performed , e . g ., by projecting the response surface into the x - y planes by assigning to each point of the x - y plane an intensity that corresponds to the value of the response surface at that point or to the corresponding tristimulus value of a color scale set previously . in a preferred embodiment , the display module 30 performs the projection of the response surface into the x - y diagram of the concentrations of the first and second anesthetics by a plurality of isoboles of the response surface being projected into the x - y plane and by the surfaces located between adjacent isoboles being covered with different colors . it is , in turn , advantageous to assign a color scale to the isobole values in advance , so that , e . g ., critical areas of the anesthetic action parameter are marked by a correspondingly intense red color , middle areas by an increasingly yellow color , and noncritical areas by an increasingly intense green color . the representation of a plurality of isoboles in the x - y plane of the concentrations corresponds to the representation of contour lines for the response surface , which is shown three - dimensionally in fig2 . an exemplary view of the display means 8 is shown schematically in fig4 . the concentration of remifentanyl is shown on the y axis and the concentration of propofol on the x axis . furthermore , four isoboles 51 - 54 , namely , for 25 %, 50 %, 75 % and 95 % probability that no reaction will develop , are shown for the anesthetic action parameter in case of probability of tolerance of laryngoscopy ( tol ). furthermore , three isoboles 55 , 56 , 57 are shown , which show the 25 %, 50 % and 75 % probability that the patient does not respond to loud shouting and shaking ( anesthesia action parameter toss ). furthermore , the display module displays the sequence of concentration data of the first and second anesthetics as a sequence of points 58 , which are connected to one another as a trajectory . the current status is indicated by a cross 59 . the line originating from the end of the trajectory with three circle symbols 60 shows the predicted concentration data for the status in 1 , 5 and 15 minutes in case the further rate of infusion is unchanged . furthermore , the module 10 for the pharmacokinetic compartment model calculations performs a model calculation for the assumption that the feed of the anesthetics is immediately interrupted . the point in time at which the awakening curve is intersected with , e . g ., 50 % toss , which corresponds to the hypothetical point of awakening in case of immediate interruption of the feed of anesthetic , is then determined in the module 10 for pharmacokinetic compartment model calculation . this expected awakening time is displayed in the display unit . the concentration data of the anesthetics , which are then predicted , are displayed by a separate asterisk symbol 61 . the data processing means 6 can also have an awakening time prognosis module , which is set up for calculating a predicted awakening time on the basis of the current concentrations of the first and second anesthetics . an awakening isobole can be determined from interaction models and the maximum concentrations for spontaneous breathing . the awakening time prognosis module sends the predicted awakening time on the basis of the current concentrations to the display module , which displays the predicted point in time of awakening in the action diagram at the concentrations of the first and second anesthetics , which concentrations are predicted for that point in time of awakening . two windows , in which the concentrations of the individual anesthetics are shown , are shown next to the action diagram in the display means shown in fig4 . the concentration curve from the beginning of the anesthesia procedure to the current point in time ( vertical line ) as well an extrapolation with predicted concentration values for about 15 minutes into the future are displayed here . the schematic block diagram of the anesthesia device according to fig3 comprises a data processing means 6 and a display means 8 . the data processing means 6 has a user interface 40 , via which the anesthesiologist can enter settings to set the anesthetics fed intravenously or by inhalation . the data processing means 6 acts for this purpose on injection pumps 4 in a controlling manner and for the administration of intravenous anesthetics and a gas dispensing means 5 for adding gaseous anesthetics , such as desflurane , sevoflurane , isoflurane and enflurane , in order to set these corresponding to the requirements for the patient 7 . the arrows in fig3 shall schematically indicate interfaces and transported data . during operation , the injection pumps 4 continuously supply data on the current rates of infusion and other data , which are useful for the determination of the status in the data processing means 6 . if gaseous anesthetics are administered , the data processing means 6 acts on the gas dispensing means 5 in a controlling manner . the action module 20 and the display module 30 may be embodied each in a separate arithmetic unit or implemented as program parts in the data processing means . while specific embodiments of the invention have been shown and described in detail to illustrate the application of the principles of the invention , it will be understood that the invention may be embodied otherwise without departing from such principles .
an anesthesia device supplying a first and second anesthetic in a quantitatively settable , controlled manner . a data processing unit with a corresponding display is set up for determining the current concentrations in the plasma or at the site of action from continuously supplied data on the quantities of the anesthetics administered with a module for a pharmacokinetic compartment model calculation and for storing these concentration values . concentration data is predicted for at least one point in time in the future . an action module provides a curve of an anesthesia action parameter as a function of the concentrations of the anesthetics . a display module displays a diagram showing the sequence of concentration of the first or second anesthetic , and the predicted concentration .