Let $\mathrm{X}$ be a cubic $d$-fold, and $\mathrm{F}(\mathrm{X})$ its Fano variety of lines. *Is the integral cohomology of $\mathrm{F}(\mathrm{X})$ torsion-free?* For $d=3$ A. Collino (`The fundamental group of the Fano surface, I') proves that there exists an exact sequence $$[\pi\_1,\pi\_1]\rightarrow\pi\_1\rightarrow\mathbf{Z}^{\oplus 10}\rightarrow 0$$ where $\pi\_1=\pi\_1(\mathrm{F}(\mathrm{X}))$ (Prop. 2.3.4 in the paper). Hence $\mathrm{H}\_1(\mathrm{F}(\mathrm{X});\mathbf{Z})=\pi\_1^{\mathrm{ab}}$ is torsion-free, which is enough. For $d=4$ Beauville and Donagi show that $\mathrm{F}(\mathrm{X})$ is deformation equivalent to $\mathrm{Hilb}^2(\mathrm{K3})$, the integral cohomology of which is torsion-free (for example by the general results of [this paper of Totaro](https://arxiv.org/abs/1506.00968)). So the only remaining case is $d>4$, where $\mathrm{F}(\mathrm{X})$ is a Fano variety in the usual sense. Higher-dimensional Fano varieties can have torsion in their integral cohomology, see for example [here](https://mathoverflow.net/questions/180514/does-there-exist-a-fano-variety-with-torsion-in-h3).



Torsion in the cohomology of Fano varieties of lines
Here is an expanded version of my comments. Let's work over the complex numbers which I suppose is assumed in the question. Let $K\_0(Var)$ be the Grothendieck ring of varieties (see e.g. <https://arxiv.org/abs/1405.5154>). Furthemore, let $K\_0(HS)$ be the Grothendieck group of integral polarizable Hodge structures with respect to direct sum operation, and let $K\_0(FinAb)$ be the Grothendieck group of finite abelian groups also with respect to direct sum operation. 


We have a composition of group homomorphisms
$$
K\_0(Var) \to K\_0(HS) \to K\_0(FinAb)
$$
where the first map takes a class of a smooth projective variety to its total Hodge structure, and the second map takes a Hodge structure to its torsion part (forgetting the weights). Section 3 in Efimov's paper <https://arxiv.org/pdf/1707.08997.pdf> gives the details for the definition of the first map, from Bittner's blow up presentation of the Grothendieck ring of varieties. Second map is straightforward. Existence of these maps implies that classes of smooth projective varieties control the torsion in cohomology groups.


Now let $X$ be a smooth cubic of dimension $n$. According to <https://arxiv.org/abs/1405.5154>, Thm. 5.1, the class of the Fano variety $F(X)$ in the Grothendieck ring is expressed as a combination of $Hilb\_2(X)$ and $\mathbb{P}^n \times X$ (with a coefficient $\mathbb{L}^2$ that shifts cohomology groups). Explicitly in $K\_0(FinAb)$ we have the following:
$$
[H^\*(F(X), \mathbb{Z})\_{tors}] + (n+1) [H^\*(X, \mathbb{Z})\_{tors}] =
[H^\*(Hilb\_2(X), \mathbb{Z})\_{tors}] 
$$
In fact, since the category of finite abelian groups has unique decompositions into indecomposables, equality of classes implies isomorphism hence
$$
H^\*(F(X), \mathbb{Z})\_{tors} \oplus H^\*(X, \mathbb{Z})\_{tors}^{\oplus(n+1)} \simeq
H^\*(Hilb\_2(X), \mathbb{Z})\_{tors} 
$$


Thus it suffices to show that $Hilb\_2(X)$ has torsion-free cohomology groups. All hypersurfaces are torsion-free, and by Totaro's result <https://arxiv.org/pdf/1506.00968.pdf>, Thm 2.2, same is true for $Hilb\_2(X)$.


