France coach Philippe Saint-Andre has made a couple of changes to his starting line-up for Saturday's RBS 6 Nations showdown against England with Jules Plisson and Vincent Debaty set to start. Stade Francais fly-half Plisson comes in for the injured Camille Lopez, who sustained a badly bruised knee during Sunday's 29-0 triumph over Italy, while loosehead prop Eddy Ben Arous has also been ruled out for the match at Twickenham as Vincent makes a start. Plisson, who impressed as he came off the bench and scored 10 points against Italy, broke his nose at the Stadio Olimpico but has been passed fit to take on leaders England. Stade Francais fly-half Jules Plisson will start for France in the Six Nations game against England . France coach Philippe Saint-Andre's (right) side still have a minor chance of winning the Six Nations . Plisson has replaced Camille Lopez in the France team to face England on Saturday at Twickenham . Saint-Andre told www.lequipe.fr: 'At Twickenham, I need players that are a hundred percent fit, and Camille was doubtful on Wednesday. Jules has a broken nose but he is determined to play. He's okay for Saturday.' Veteran France prop Thomas Domingo had been tipped to replace Ben Arous as he joined up with the squad for training this week, but Saint-Andre believes he has sufficient cover on the replacements bench in Uini Atonio and Rabah Slimani. He added: 'With Uini Atonio and Rabah Slimani, we have two versatile players. 'It's hard for Thomas (Domingo) but it is difficult to assimilate into two training sessions (what is needed). We trust those who are with us from the start of the Six Nations.' Lopez (right) sustained a badly bruised knee in the 29-0 victory over Italy last weekend . Vincent Debaty starts ahead of Eddy Ben Arous, who has also been ruled out with injury . Saint-Andre believes that the versatility of players such as Uini Atonio is key to his team's strength . Les Bleus' victory last weekend - their second of the tournament - took them to within two points of England, who sit level with Ireland and Wales. There is still a slight chance France can lift the trophy if they can beat England on their home turf and the other two results go their way with Wales travelling to Italy and Scotland at home to the Irish. VIDEO Robshaw sets sights on France following Scotland win .
France take on England in a dramatic Six Nations finale on Saturday . Both teams play at Twickenham with a chance of winning the competition . Jules Plisson and Vincent Debaty come in for France against England .