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license: cc-by-4.0
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## Citation
DepMap, Broad; Corsello, Steven; Kocak, Mustafa; Golub, Todd (2019). PRISM Repurposing 19Q4 Dataset. figshare. Dataset.

Current dataset: [https://doi.org/10.6084/m9.figshare.9393293.v4](https://doi.org/10.6084/m9.figshare.9393293.v4)

General guidance: [https://doi.org/10.1101/730119](https://doi.org/10.1101/730119)

## Dataset Fields
- **broad_id**: ID used to identify drug-batch combinations
- **name**: Name of the drug
- **depmap_id**: ID to identify a cell line
- **ccle_name**: ID to identify a cell line
- **screen_id**: ID to identify a screen
- **upper_limit**: Limit of the curve as dose approaches infinity
- **lower_limit**: Limit of the curve as dose approaches zero
- **slope**: Slope of the dose-response curve
- **r2**: Goodness of fit measure between dose-response curve and replicate viability data
- **auc**: Area under the dose-response curve
- **ec50**: Dose at the inflection point of the dose-response curve
- **ic50**: Dose that corresponds to a viability of 50 on the dose-response curve
- **moa**: Broad Repurposing Hub mechanism of action annotation
- **target**: Broad Repurposing Hub gene target annotation
- **disease_area**: Broad Repurposing Hub disease area annotation
- **indication**: Broad Repurposing Hub indication annotation
- **smiles**: Simplified Molecular Input Line Entry System (SMILES) molecular identifier
- **phase**: Broad Repurposing Hub latest clinical phase annotation
- **passed_str_profiling**: Indicator for problems identified by STR profiling