My mom has ESRD, PVD.  She has been on Metoprolol, Cardizem, Lasix, Coumadin (Afib), recently had Digoxin added because her heart rate at rest is 118bpm Per nephrology .125mcg QOD is ok.  She has started this leg weakness.  She  gets up and starts shaking, she feels like she is going to fall.  She had this occur several months  ago when she was on MultaK, when this stopped, so did these symptoms.  The only newer meds are the Cardizem about 3 months ago and the recent DIG.  She was evaluated by Neurology when this occured in the past and they said that it did not appear to be TIA or Stroke.  Could it be due to build up of waste?  It just is odd that it stopped for a long while and now all of the sudden, 2 weeks post Dig. beginning it started.  I also wonder if it is possibly related to decreased blood volume?I know this is complex, I just dont get any good answer on cause, Per nephrology, it is not that, Per Neurology it is not that, Renal and Cardiology keep thinking possible TIA.  She has a Pacer so she is unable to have MRI and we cant use Dye for CT.  I wonder if we are not seeing something possibly?                   Thanks,
Hello their have noted the history with great interest Hope her electrolyte levels are fins because that's one thing that needs to be monitored in patients of ESD.Also, she is on too many Chat Doctor.  I want to look at the etc interval on every difficult to assess on old basis . She needs to be put in the hospital and then evaluated Hope that helps