Hello Doctor, I am a female 65 years old , last year I had a bypass anastomossis for heart revascularization, I take the following medecines: 1 cartia 100mg 1 lipitpr 80g tab. now reduced to 40mg 1 metoprplol tartrate 100mg and my GOT AST is 78 U/L GPT alt is134 GGT is 58 U/L Is this Situation curable? Awaiting your reply, thanking you in advance, Very Much
Hello. Thanks for posting here. I have gone through your description. Lipitor can cause increase in the liver enzymes. Your liver enzymes are high but not very high to stop Lipitor. I guess that's why your doctor has reduced the dose to 40 mg. If the liver enzymes GOT and SGPT are greater than 3 times the normal range, they are stopped. These levels usually come down when stop therapy or reduce your Lipitor dose. So in short, this is a reversible increase in the enzymes. Please continue Lipitor at 40 mg and do an LFT after two weeks. If the levels continue to increase, then statin can be stopped for a period of four weeks. We must also consider the probability of fatty liver disease in this case, which can also cause increase in liver enzyme levels. Please do a sonography of the abdomen to rule out fatty liver disease. CARTA and metoprolol do not affect liver enzyme levels and can be safely continued. Wishing you good health. Regards