I have been on many SSRI s over the past 26 yrs. I seem to develop a resistance to them after varying lengths of time. When this has happened, my psychiatrist switches me to another drug or adds a drug. While on medication last year I had a depressive episode, possibly triggered by my son & his family moving overseas. I was given Fetzima in addition to buproprion, which I have been on constantly for many years. I have never felt completely better since this episode. This weekend it reach crisis stage, inability to get out of bed, constant crying and for the first time, suicide ideation. Then I began reading about tardive dysphoria which made me feel even more hopeless. It seems with medication I will continue to get worse but without medication, I will surely get worse. Is it hopeless?
Hi, thanks for the query. It's very sad to know that you are still not able to recover despite treatment for depression. In a sizable number of patients (almost 33%) trials with many Chat Doctor.