Male patient 79 wipple procedure in 2011 for pancreatic cancer. Uneventful recovery and subsequent chemo with Gemzar (3 cycles only) suspended for allergic reaction (pneumonia). Markers normal up until July 2014 (Ca 19 7.9 , CEA 66 , Ca 125 67) follow up. He has COPD well managed and Bell paralysis. Waiting for consult with Ent for ear pain (neurologist strongly suggest the possibility of occult shingles ). Can CEA and Ca 125 increase be related to Herpes zooster?
Hi, Thanks for writing in. It is important to know the baseline value of CA 19, CEA and CA 125 and the variation in levels after Whipple and chemotherapy. These are tumor markers and not always specific to the condition. However, a certain tread might be seen with progressive cancer. The treatment for pancreatic cancer is difficult. Your patient is lucky to have an operable tumor of pancreas and most patients are detected with the disease at advanced stage. Many infections and inflammations might cause increase in CEA and CA 125 levels however it is not specific to herpes zoster infection and manifestation. Please do not worry.