Can zoloft cause more anxiety and depression even on a lower dose. Also can it effect how well Valium works in your body. I have been on zoloft and valiun for over a year, but with no results. Is there a medication that can keep you calmer and more relaxed. Thank YOU
HiT hanks for using Chat Doctor Zoloft is a very good antidepressant and has good effect on anxiety or depression. At low dose, it would not show good effect. Effective dose of Zoloft is more than 100 mg. In case, your dose is less than 100 mg, then you should ask your psychiatrist to increase the dose up to 200 mg per day rather than to shift to another antidepressant. Thanks