My husband just had back surgery.  He was prescribed Amlopdipie besylate 50mg. Hes blood presuure is still high at 188/123. no nausia, no dizziness. At the hospital, he was not released until his BP was below /100.  Not sure if it is normal to take some time for the medicine to work.  He was released 2 days ago.
Brief answer :You need to see your doctor to change or to add any other medication to get a normal blood pressure. Detailed answer:You are right on making this question. Thank you. The blood pressure of 188/ 123 mmHg is really high and has to be treated. Amlodipine desolate is a good medication in his conditions, but seems it is not enough, for the moment. It takes at least 8 hours to reach the peak level in blood, and 3 -4 days to stabilize the blood pressure. So for this 3-4 days after admission from the hospital, he has to add any other blood pressure medication that acts fast, for example Zapotec (enalapril) 10 mg once a day. It begins to act in 20 minutes and has less side effects. If after 4 days the blood pressure is not yet stabilized, then you need to see your doctor to review the treatment. Please feel free to make any other question you need. Kind Regards,