My husband got his first Lupron depot 22.5 mg shot for prostate cancer on Wednesday 2/19/14. He is to get this shot every 3 months but now is very hesitate to have any further shots.   He is constantly hurting in the hip and falling.  He also has spasms in his calves.  This is something he has not had problems with before.  I am very concerned as this is getting worse instead of better.  Please advise what we should do and/or take to stop this from happening.
It means the disease at the hip is active and there is no response to leuprolide. It is better to get hip irradiated to get the relief in pain.