my mother aged 58 years.  She is having head ache for the past 1 year.  When the CT scan of brain plain was done, the report says that there is gliotic changes in brain.  please suggest me whether it is permanently curable by medicine or not with details.
Hello! Welcome on Chat Doctor ! These CT scan findings are suggestive of small vessel disease, which is related to uncontrolled high blood pressure or diabetes. From the other hand, migraine can lead to such changes. For this reason, I would recommend you to closely monitor her blood pressure values and start antihypertensive therapy in case of uncontrolled hypertension. Taking daily aspirin 80-100 mg is necessary (if no contraindications), to help stop the progression of these changes. There is no treatment for such changes, just prevention of further progression. In case her blood pressure values are normal, I would recommend starting a calcium channel blocker (verapamil) or topiramate to help improve her headache. But it would be better consulting first with a neurologist in order to determine the exact type of headache and proper treatment. Hope you will find this answer helpful! Best wishes,