Mid afternoon yesterday I experienced severe itching on my palms and sides of hands. I work with fabrics, mostly imported and assumed it was a contact dermitis problem. When I came home later in evening, itching completely stopped. Went to bed about 10:30 PM. Experienced some inner ear and throat itching. Dismissed it as normal allergies. Around 12:30 PM, I awoke and had extreme swelling in my lower lip and chin area. I immediately took Benadryl and ice pack treatment. Continued this until approx. 4 PM. Swelling is very minimal now. Should I be concerned?
Hi, your history signifies a late phase allergic reaction.  Need more investigations and history. If it happens again. Get yourself evaluated.