Friends husband with enlarged spleen and liver, fever as high as 104, headache with only the edge taken off by Vicoden and fatigue x 1 wk (lyme negative, spinal tap done for meningitis, blood cultures done and pending).  Head CT negative.   Only taken to small community hospital  - West Nile Virus and Rocky ? Spotted fever
Hi and welcome to Chat Doctor. Thank you for your query. I am Chat Doctor, I understand your concerns and I will try to help you as much as I can. Enlarged spleen is called splenomegaly and there are various causes possibly leading to this. In first case these are infections such as mononucleosis Parasitic infections, such as toxoplasmosis or Bacterial infections. It means that any infection in your body may lead to spleen enlargement.  Second most common causes include autoimmune diseases such as thrombocytopenia. If this is ruled out by specific tests then some other causes may be considered and some are more or less serious such as Leukemia Lymphoma, or noninflammatory diseases such as acidosis, lupus, and rheumatoid arthritis. In every case, infectious causes are treated with antibiotics and other causes may require surgical removal of spleen. I hope I have answered you query. If you have any further questions you can contact us in every time. Kindly regards. Wish you a good health.