hi i am a patient of psoriasis as well as psoriatic arthiritis and was on a 10mg dose of methodroxate from last 2 years recently my disease flaired as told b my doc. rite now have acute pain in my knee and a little pain in my ankle .as advised my dose for methodroxate has been increased to 15mg per week and told to have 2ml depomedrol injections for 4 week (once a week)having depo for three week till now there has been no improvement in my knee and i feel weekness in the my partcular right leg in which i have pain please suggest what to do now?email id : YYYY@YYYY
Sometimes other medicines are also added with methotrexate for example HY Chat Doctor.  You have little choice but to either accept your current doctor or consult another rheumatologist who may add up medication seeing more joints involvement