I have had two ESI injections In November 2011 within 13 days of each other. After the second injection I gained 10 pounds within a week, I am 120 pounds and have been consistent with that for 20 years and before that I weighed less. I am 5 6 and 46 years old with exercise as part of my life. I have always had a fast matabolism but since this injection I cannot get the 10 pounds off, not even one ounce. How long does this cortisone injections last in your body and what has it done to my metabolism?
Hello, Cortisone half life 6-8 hours. Three to four half lives 95% of the Chat Doctor.  Don't worry present condition may be due to some other endocrine problems. Please consult with your endocrinologist he will examine and treat you accordingly. Take care. Hope I have answered your question. Let me know if I can assist you further.