Generate a series of (instruction, response) pairs that are similar in context and structure to the example provided below. Each pair should consist of a concise instruction followed by an appropriate, detailed response. The instruction should pose a clear task or question, while the response should provide a comprehensive answer or solution that could be understood by someone with a basic understanding of the subject.

Example pair: 
Instruction: Please condense this book review so it will fit into a tweet, and give it the tone of a tweet as well:

*Spoiler Alert*

You couldn't have prised this out of my hands initially.

However, somewhere at the 60% region, it got bogged down by too many flash-fires while our protagonist, Ryland Grace, the ultimate Gary Sue and the purveyor of all things Space/Biology/Physics/Chemistry/Engineering/Math/Music/Language/Etc, got progressively more facetious and irritating.

Like a modern-day John McClane (but in space) and with astrophage as the villain. The bumbling White guy who we all know will save the day. He even saved the aliens. Imagine that?

The only good thing about this book is Rocky the Eridian.
Response: #Spoilers: 

This book started off great. Unfortunately, by the 60% mark, the protagonist was clearly too perfect at everything (chemistry, math, music, language, etc.) - a bumbling John McClane in space. It was a foregone conclusion that he'd save the day. Rocky was cool, tho.

Your task is to generate more pairs that maintain this level of clarity and detail. The topic is Summarization. Write a long text of instruction by yourself, then summarize the given instruction in a response. Ensure that the responses are informative and accurate, suitable for an educational context. 

Store the generated pairs in valid JSON format, with each pair as an object within an array. Each object should have two key-value pairs: "instruction" and "response". For instance: 

{"contents": [{"instruction": "text", "response": "text"}, {"instruction": "text", "response": "text"}, ...]} 

Remember to maintain consistency in the format and ensure the generated pairs are diverse and cover a broad range of subjects. You must return the response in the asked format and you must not add any additional text in your response.

Explain the importance and functions of the human circulatory system for a middle school biology quiz.
user
The circulatory system is crucial because it transports blood, nutrients, oxygen, and waste products throughout the body. The heart pumps blood through a network of arteries, veins, and capillaries. Blood delivers oxygen and nutrients to cells and removes carbon dioxide and waste. It also helps regulate body temperature and protect against disease.
assistant