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The BiBiServ team discontinued the online service for MoRAine. Please contact the author(s) of MoRAine for any questions concerning MoRAine.
MoRAine is a tool for reannotation of transcription factor binding motifs and the creation of sequence logos.
It reasseses the given binding sequences, by swicthing the strand annotations, and by shifting the motifs in order to maximize the information content of the corresponding position specific scoring matrix.
ROCOCO reconstructs ancestral gene clusters. Given the topology of a phylogenetic tree and the gene orders of the leaf nodes, it calculates optimal sets of gene clusters for the inner nodes. The optimization criterion combines two properties: parsimony, i.e. the number of gains and losses of gene clusters has to be minimal, and consistency, i.e. for each ancestral node, there must exist at least one potential gene order that contains all the reconstructed clusters.
The underlying model, the labelling problem and the method are introduced in [STO:WIT:2009] by Stoye and Wittler. A more recent, extensive description can be found in [WIT:2010]
In the current version (2.0), two sequence-based gene cluster models are included. That means, paralogs in the gene order are incorporated in the model. ROCOCO provides a graphical user interface (ROCOCO-Compare) to compare and explore the reconstruction results. You can load results from different internal nodes or from different gene cluster models to look for similarities or search for specific genes. You can download Rococo-Compare as a jar archive from the dowload page or execute it using the Java WebStart technology.
71So the king and Haman went in to feast with Queen Esther. 2On the second day, as they were drinking wine, the king again said to Esther, What is your petition, Queen Esther? It shall be granted you. And what is your request? Even to the half of my kingdom, it shall be fulfilled. 3Then Queen Esther answered, If I have won your favour, O king, and if it pleases the king, let my life be given methat is my petitionand the lives of my peoplethat is my request. 4For we have been sold, I and my people, to be destroyed, to be killed, and to be annihilated. If we had been sold merely as slaves, men and women, I would have held my peace; but no enemy can compensate for this damage to the king.* 5Then King Ahasuerus said to Queen Esther, Who is he, and where is he, who has presumed to do this? 6Esther said, A foe and enemy, this wicked Haman! Then Haman was terrified before the king and the queen. 9Then Harbona, one of the eunuchs in attendance on the king, said, Look, the very gallows that Haman has prepared for Mordecai, whose word saved the king, stands at Hamans house, fifty cubits high. And the king said, Hang him on that. 10So they hanged Haman on the gallows that he had prepared for Mordecai. Then the anger of the king abated.
20 Mordecai recorded these things, and sent letters to all the Jews who were in all the provinces of King Ahasuerus, both near and far, 21enjoining them that they should keep the fourteenth day of the month Adar and also the fifteenth day of the same month, year by year, 22as the days on which the Jews gained relief from their enemies, and as the month that had been turned for them from sorrow into gladness and from mourning into a holiday; that they should make them days of feasting and gladness, days for sending gifts of food to one another and presents to the poor.