Austin is just a little over an hour away, so it's no big deal to run up there for an afternoon. Whether we stay for a few hours or a few days (like we did last week while Nick attended a conference), we tend to keep to a routine of places to shop and eat.
Could this be the best book store in the country? Easily. I say this with authority, because I am a book store tourist. (I would put used book stores in a separate category.) I've been to Powell's, I've been to The Strand. I still put this one at the top because its scope is thorough without being overwhelming. Also, great periodicals, children's section, author events, and coffee shop.
There is plenty of good food in Austin, but we go here every trip. Maybe because it's right across the street from Book People? At first, yes, but I think we would go back even if it were out of the way. Their motto should be "Never Not Good Food." Chicken and waffles if you feel like punishing yourself.
Right next door to 24 Diner, because the universe conspired to put three of our favorite Austin things in one spot. In truth, I don't usually go into Waterloo. I spend extra time in the book store while Nick shops for records. It's one of my favorite places because it makes him happy.
I still don't exactly know how to categorize this place. We go in there at 6 p.m., it's fairly empty, we are escorted to a doilied dining room for dinner. Dinner starts with complementary shots of icy vodka, bread, salt, and raw onions. And the food is good, and Mamie likes it, and I'm still sort of confused by the whole thing. I think it turns into a raging vodka bar after dark, so I feel strange taking my baby there.
Mmmmm, incense. Oils, teas, cards, crystals, books, and more. Even if you don't know what you're looking for, you'll find something magical. Unless your toddler is handsy like mine and decides she really needs that Buddha statue. Then you have to leave without buying anything.
I have to confess -- I've never bought anything here. This is the point in our Austin tour when Mamie starts to break down, and this store is a little too small and close to contain her emotions. But for the few minutes I get to browse, I see amazing special signed copies, gorgeous vintage editions. This is a bibliophile's store.
Yeah, I said it. There is no Ikea in San Antonio, so it's nice to make a trip (technically in Round Rock, north of Austin). It's ok to like something that's not weird and indie!
(*If you like BBQ, get BBQ. It will be good if your expectations are calibrated for what Texans consider BBQ. In other words, prepare to be disappointed if you want pulled pork and delighted if you like sausage or brisket. Don't feel like you have to go somewhere and stand in line for two hours to get "good" BBQ. All the BBQ is pretty good. That said, Stubbs is a special experience, especially on Gospel Sundays.)
Saturday night I tried really hard to get out of cooking dinner. No, I'm not perpetually steam-drenched, hunched over the stove every night, just looking for one night off. I have just about every night off because Nick cooks most of the time, and when it's my turn, I tap into my arsenal of delivery services.
Saturday night, I did, very begrudgingly, grate carrots and sauté bokchoy and glaze chicken. Nick said, "You don't seem to like cooking." But... but... but, I wanted to defend myself, I know how to cook; I used to cook; I used to like cooking.
For example, kids. Feeding kids for the last 4.5 years has consumed me, no apology for the pun. My obsession with managing their growth and nutrition is totally separate from cooking. It's a mental tally of macronutrients and micronutrients; it's creating the perfect veggie snack plate with every cucumber slice salted; it's composing and blending superfood sm…
Early 1980s, summer smells like pool water and cheese crackers from the vending machine at the city pool. And 7-Up in a can because at least one summer, it seemed like we had endless cases of 7-Up in the porch fridge. (I assume you are familiar with the porch fridge.)
I don't know who took me to the pool (Mom? Grammaw?); I don't know if I wore a seatbelt in the backseat; I don't know if anyone ever put sunscreen on me.
But I know what the combination of pool water, cheese crackers, and 7-Up smells like -- a sense memory 35 years old.
Early 1990s, summer smells like pool water, cigarette smoke, and NO-AD tanning lotion in Stacey's backyard. After the sun set, it smelled like plumeria lotion on hot tanned skin and B.C. Moore's parking lot. I never got close enough to a boy to smell Drakkar Noir.
Stacey's mom is gone since last year, and no one smokes cigarettes anymore. I feel so deeply hurt for my oldest friend to have lost her mother and so disoriented to be in…
I just created a document to list the words I've heard Lizzie say. I count 14, but I haven't consulted with Nick or her grandparents to see if I've missed any. I'm doing this homework so when people question me about her development, I can say assuredly whether or not she is meeting her milestones. This week I was ashamed to not know whether she typically leads with her right or left foot, or if she often kneels while playing, and if so, are her hips bent or straight? What direction does the third finger on her left hand point while she lays in bed on the night of a full moon? There are so many things I didn't realize I should be noticing.
So many nagging lists of things a child "should" be doing. I think "should" implies some moral imperative or an obligation to meet external expectations, and I swear the word doesn't apply to a baby.
I have been a librarian, a newspaper reporter, a market researcher for a national farming magazine. Now I am a mother compelled to model passionate pursuits for my daughters. My passionate pursuits are writing, wellness, and creating a family community among the people we love and learn from. This blog is about what I'm doing, learning, reading, and obsessing over. Pretty things, crazy things, secret things.
The USA Book: A Journey Through America by Carla Zimmerman Last year a copy of the compact version of Lonely Planet’s The Travel Book came into my hands and it was a fascinating but brief tour around the world. (See my write-up here.) That small sized book was a lavish 900 page brick, so when Read More
By now you might have cottoned on, by the series of bookish but not books-read posts, that I’m suffering a severe case of end-of-term-can’t-read-itis and have thus resorted to fillers; (all this pondering the stats is helping me formulate my books of the year though). Aside from that, I am reading The Moonstone but mostly Read More
Posted in 2009, Non-fiction, Reading Resolutions, Year in Review Tagged Memoir, Non fiction Leave a comment
It’s my great pleasure today to introduce you to Marcus Chown, author of We Need To Talk About Kelvin who is on a blog tour to promote the book (which I reviewed here). Apart from writing great popular science books, Marcus is cosmology consultant of magazine New Scientist, having formerly been a radio astronomer at Read More
Posted in Author Q and A, Authors C, CHOWN Marcus, Science Tagged Non fiction, Science Leave a comment
On Wednesday, I am delighted that Marcus Chown, author of We Need to Talk About Kelvin: What Everyday Things Tell Us About the Universe” will be visiting my blog to do a Q&A as part of his blogtour to promote the book. Marcus is a best-selling science author and cosmology consultant for New Scientist magazine. Read More
Posted in Authors C, CHOWN Marcus, Non-fiction, Science, Title begins with W Tagged Non fiction, Popular Science, Science Leave a comment
Don’t Swallow Your Gum: and Other Medical Myths Debunked by Dr Aaron Carroll and Dr Rachel Vreeman This short book looks into about seventy-five medical myths and old wives tales, examines the evidence, and debunks them. Many will have read Ben Goldacre’s bestselling book Bad Science – (If you haven’t read it, do! My review Read More
Posted in Authors C, Authors V, Title begins with D Tagged Non fiction, Popular Science, Science Leave a comment
The Travel Book by Lonely Planet Here’s my full written review… This is the new smaller format edition of Lonely Planet’s previous coffee table giant, but it’s still a doorstoppingly thick brick of a book! It has to be 900 pages to give even the tiniest snapshot of every country in the world, (plus a Read More
The Tipping Point by Malcolm Gladwell I’ve just finished my first book in 2009, although started in 2008. The Tipping Point by Malcolm Gladwell is an immensely readable analysis of what makes epidemics happen. However its not really about nasty diseases, although they do feature, but more about business and marketing. It is not just Read More
Posted in Authors G, GLADWELL Malcolm, Title begins with T Tagged Business, Economics, Non fiction, Philosophy Leave a comment
Brewer’s Dictionary of Phrase and Fable Some may consider choosing an encyclopaedic dictionary a bit of a cheat, but I maintain that if you were on a desert island with no internet – there is no better book than Brewer’s for frequent dipping into for little nuggets of information. It is simply the original and Read More
Posted in 5 Star Books, Desert Island Books, Reference Books, Title begins with B Tagged Fable, Myths and legends, Non fiction Leave a comment
From the sublime … “The marvellous thing about a joke with a double meaning is that it can only mean one thing.” Ronnie Barker … to the sublimely ridiculous but still true… “A sure cure for seasickness is to sit under a tree.” – Spike Milligan “Never trust a man, who when left with a Read More
My eight year old daughter recently asked me what my favourite film is. She probably meant which is my favourite film of hers … but I quickly replied The Blues Brothers. Not the best film ever made, and a close run for my top place to Excalibur, but The Blues Brothers was the film that Read More
Posted in Authors W, Non-fiction, Title begins with W, WOODWARD Bob Tagged Comedy, Film, Non fiction Leave a comment
My sister-in-law has a book out and it’s a real retro nostalgia trip. I saw the manuscript earlier this year, and it got us all talking for hours about stories of our own school dinners when we were little – loved and loathed in equal measure I think. And as for the dinner ladies … Read More
Can you have more than one book at a time on the go? In other words are you a serial monogamist or a two-timer in your relationship to your reading materials? I’m always impressed by people who can manage to read several books at a go, swapping between them as the mood takes them and Read More
Posted in Authors S, Reading & Reviewing habits, SUMMERSCALE Kate, Title begins with S Tagged Non fiction, Reading habits, True Crime Leave a comment
BOOKLOVER, lifelong reader and Co-founder/ Fiction Ed of Shiny New Books. I'm also a Mum, materials scientist and school Lab Tech living near Oxford. More on the 'Info & Stuff' tab. Contact me: annabookbel @ gmail . com
© AnnaBookBel 2018. Unauthorised use and/or duplication of this material without express and written permission from this blog’s author and owner is strictly prohibited. Excerpts and links may be used, provided that full and clear credit is given to AnnaBookBel with appropriate and specific direction to the original con
What Happens to Heart Valve Damage Caused by Diet Drugs after Treatment with the Drug Has Been Stopped? | Annals of Internal Medicine | American College of Physicians
What Happens to Heart Valve Damage Caused by Diet Drugs after Treatment with the Drug Has Been Stopped?
The summary below is from the full report titled “The Progression of Fenfluramine-Associated Valvular Heart Disease Assessed by Echocardiography.” It is in the 20 February 2001 issue of Annals of Internal Medicine(volume 134, pp 261-266). The authors are ST Mast, JG Jollis, T Ryan, KJ Anstrom, and JL Crary.
Summaries for Patientsare a service provided by Annalsto help patients better understand the complicated and often mystifying language of modern medicine.
Summaries for Patients are presented for informational purposes only. These summaries are not a substitute for advice from your own medical provider. If you have questions about this material, or need medical advice about your own health or situation, please contact your physician.
In 1997, two drugs used to decrease appetite, fenfluramine and dexfenfluramine, were found to cause abnormalities of the heart valves in up to one third of people who had taken them. As a result, these drugs were withdrawn from the U.S. market. No one knows with certainty, however, what happens to heart valve function once treatment with these drugs have been stopped.
To find out whether valve abnormalities got better, got worse, or stayed the same after treatment with fenfluramine drugs has been stopped.
Fifty patients with at least mild abnormalities of the heart valves who had taken fenfluramine drugs (sometimes in combination with other diet drugs) and were followed for at least 100 days after treatment with the drug had been stopped.
All patients had a first echocardiogram after stopping treatment with the drug and had a second echocardiogram at least 100 days later. (An echocardiogram is a picture of the heart created by using sound waves; it can be used to look at heart valve function.) All echocardiograms were reviewed by two cardiologists who did not know which study was performed first. The specific valve involved, type of abnormality, and severity of damage were recorded.
The two valves on the left side of the heart (mitral and aortic) were most commonly affected, allowing blood to leak backward after the valve should have closed completely (regurgitation). On the first echocardiogram, 38 patients had abnormal mitral valve function; on the follow-up echocardiogram, valve function was unchanged in 19 patients, had improved in 17 patients, and had worsened in 2 patients. Among the 43 patients with aortic valve abnormality on the first echocardiogram, this abnormality remained unchanged in 22 patients, had improved in 19 patients, and had worsened in 2 patients. The two valves on the right side of the heart (tricuspid and pulmonic) were less commonly affected. Tricuspid abnormality was found initially in 29 patients; during follow-up, 9 patients had no change, 18 had improved, and 1 had worsened. Pulmonic abnormality was found initially in 11 patients; 1 had no change and 9 improved during follow-up.
Patients in the study had echocardiograms because problems suggesting heart disease had developed. People who took the drug but did not develop symptoms suggesting heart problems were not studied. Moreover, for the many patients who initially had severe valve abnormalities, the only change that could be observed was improvement. The researchers also could not tell if the patients had heart valve damage before they took the diet drugs. Finally, the follow-up period was relatively short.
Most heart valve abnormalities that developed in people who took the diet drugs fenfluramine and dexfenfluramine improved or remained stable over time after they stopped taking the drug, although a few became worse.
The In the Clinic® slide sets are owned and copyrighted by the American College of Physicians (ACP). All text, graphics, trademarks, and other intellectual property incorporated into the slide sets remain the sole and exclusive property of the ACP. The slide sets may be used only by the person who downloads or purchases them and only for the purpose of presenting them during not-for-profit educational activities. Users may incorporate the entire slide set or selected individual slides into their own teaching presentations but may not alter the content of the slides in any way or remove the ACP copyright notice. Users may make print copies for use as hand-outs for the audience the user is personally addressing but may not otherwise reproduce or distribute the slides by any means or media, including but not limited to sending them as e-mail attachments, posting them on Internet or Intranet sites, publishing them in meeting proceedings, or making them available for sale or distribution in any unauthorized form, without the express written permission of the ACP. Unauthorized use of the In the Clinic slide sets will constitute copyright infringement.
Factors Related to Bacterial Vaginosis That Persists or Occurs Again after Treatment in Women Who Have Sex with Women
Radical polymerization-crosslinking method for improving extracellular matrix stability in bioprosthetic heart valves with reduced potential for calcification and inflammatory response.
Familial clustering of bicuspid aortic valve and its relationship with aortic dilation in first-degree relatives.