Transient receptor potential cation channel subfamily, member 3. Activated by muscarinic receptor activation. An alternative ion permeation pathway in TRPM3 allows large inward currents upon hyperpolarization, independently of the central pore. Four residues in S4 (W982, R985, D988 and G991) are crucial determinants of the properties of the alternative ion permeation pathway (Held et al. 2018). ().
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