LIFEx reads DICOM images locally or over a network using a DICOM browser, is compatible with Osirix and includes a powerful 3D reconstruction-based slice viewer. Volume of interest (VOI) can be either imported from previously created files or drawn and manipulated using LIFEx. Results are exported in Excel format files. LIFEx runs on Windows, MacOs and Linux. It is distributed with examples and includes a tutorial. User support is offered. Users can optionally contribute to the gathering of index values in different tissue types and different images as a public data bank of reference values is currently being built and integrated to the software for assisting the users with the interpretation of their results.

This release includes:

New software features:
- possible setting of the voxel size in which textural features are calculated in texture protocol
- management of multi-series with common ROI

File handling:
- PET images displayed in Bq/mL Units when conversion into SUV unit is not possible (missing Dicom fields)
- fixed bug: modification of problematic slash into PatientName DICOM field  when saving results of texture protocol in an xls file
- fixed bug: oblique images now properly displayed when "orientation matrix » DICOM field is not null

Algorithms and utilities:
- refinement of the ROI position to calculate SUVpeak in PET: difference ≤ 0.01 between new SUVpeak compared to the one calculated in previous LIFEx regions

VOIs and paint:
- fixed bug: error in displaying ROI statistics when multi-series were loaded simultaneously
- fixed bug: Nestle ROI calculation was refined
- new tool: ROI erosion with defined voxels or spacing
- new tool: ROI dilation with defined voxels or spacing
- pencil2D tool: increased line width and added color at drag handle point. The Press "e" option was introduced to close (end handle point) ROI

Images and paint:
- change in maximum zoom factor of displayed image: images can be zoomed 4 times more
- addition of a low/high switch for quality rendering on images canvas with pressing the "s" key
- display of the position and value of the cursor for each loaded image series

Texture:
- addition of a saving option (xls format) of the diplayed histogram values
- texture script are no longer stalled when a MIP view has been displayed
- removal of the empty row between title and values in the xls texture files
- addition of the SeriesDate field in the xls texture files

Miscellaneous, fixed and checked issues:
- correct setting of the ROI when displayed on an image series different from the one that was used to create the ROI
- cleaning a some stalled information messages

Documentation:
- UserGuide \ Nestle Segmentation, p.33: V (threshold) is changed into T (threshold) for clarity
- UserGuide \ tools GUI: Addition of the dilate/erode tools help
- AppendixTexture: Addition of the multi-series management