on the handle and Kercher 's DNA on the blade . The defense disputes that , but last Friday , the court denied the request for a review . Closing arguments in the trial are expected at the beginning of November , and Knox 's parents hope a verdict will finally vindicate their daughter . Watch Curt Knox say why he thinks his daughter was arrested '' Her father , Curt Knox , told CNN that he thinks Amanda Knox was targeted as a suspect from the beginning . Within days of Kercher 's murder , Knox and her then-boyfriend , Raffaele Sollecito , were questioned and portrayed in the media as the undisputed killers . `` I believe that there was a huge mistake made very , very early on by , you know , having a -- literally a ` case closed , ' you know , presentation by the police over there , '' he said . Prosecutors held news conferences weeks after the killing , declaring the case solved . Knox , Sollecito and bar owner Patrick Lumumba were believed to have killed Kercher during a sexual game gone horribly awry . Knox was criticized in
-LRB- CNN -RRB- -- Amanda Knox 's parents are hopeful that an Italian court 's decision not to re-evaluate the evidence against their daughter means she will be found not guilty of killing her roommate . Edda Mellas and Curt Knox say they have never believed their daughter was guilty . `` We asked for the independent review because we were sure that anybody -LSB- who -RSB- independently looked at it would support our position , '' Edda Mellas , Knox 's mother , told CNN 's Larry King in an interview to air Friday night . `` Now , maybe the court decided that they do n't even need that support . That our arguments have already been good enough . '' Knox , of Seattle , Washington , has been in an Italian jail and on trial for nearly two years on charges that she helped murder her roommate , British student Meredith Kercher . Knox 's defense lawyers had asked the court for an independent review of the evidence , which can be requested if there is contested or contradicting evidence . Prosecutors say a kitchen knife , allegedly the murder weapon , has Knox 's DNA