PARIS , France -- Top-seeded Maria Sharapova was a shock casualty at the French Open on Monday when she crashed 6-7 7-6 6-2 against fellow Russian Dinara Safina in Paris . Ecstasy : Safina releases her emotions after her comeback win over Maria Sharapova in the French Open last 16 . Bidding for the only Grand Slam title she has yet to win , new world No. 1 Sharapova twice blew big leads in the second set . Sharapova 's customary screeches reached maximum volume as the match slipped away , and the noise seemed to annoy fans . They whistled and booed Sharapova as she left Court Suzanne Lenglen after the match , and she did n't acknowledge the crowd . `` I ca n't please everyone . It 's not in my job description , '' she said . `` I 'm an athlete , and I go out there and fight my heart out . They paid the ticket to watch me , so they must appreciate me on some level , right ? '' Sharapova won five consecutive games in the second set to go ahead 5-2 , and held a match point serving in the next game . She also led 5-2 in the second tiebreaker before losing five consecutive points , then unraveled down the stretch , losing the final four games and 10 of the last 12 points . It was the latest setback for Sharapova on clay , her least-favorite surface . `` On this stuff , things happen in a hurry , '' she said . `` It was all in her hands , '' Safina said . `` Then suddenly it changed . '' Safina , the younger sister of two-time Grand Slam champion Marat Safin , duplicated her upset of Sharapova in the fourth round at Roland Garros in 2006 . She received a congratulatory text from her brother and said she hopes to join him as the winner of a major title . `` A dream of all our family , '' she said . `` Once we do this , we can put the racket on the wall and say we did everything we could . But to get to his level , I still have to work a little bit harder . '' The No. 13-seeded Safina 's next opponent will be No. 7 Elena Dementieva , who won another all-Russian matchup against No. 11 Vera Zvonareva , 6-4 1-6 6-2 . Trailing Sharapova 5-3 in the second set , Safina saved match point with a backhand winner , then broke two points later when Sharapova pushed a forehand wide . In the second tiebreaker , Sharapova double-faulted for 5-4 and then hit three errant backhands . That evened the match , but the momentum favored Safina . Sharapova 's customary squeals during rallies became more intense during the sixth game of the final set , and she screamed at herself after points . `` Just trying to pump myself up , '' she said . `` I was trying to get angry about something . I just started playing tentatively . '' She erased three break points before conceding the game with a forehand into the net . That gave Safina a 4-2 lead , and she closed out the victory , falling to her knees with glee when Sharapova socked a wild forehand on match point . It was latest in a series of memorable victories over the past month for Safina . She was the last player to beat recently retired Justine Henin , a four-time French Open champion . That upset came on clay in early May at Berlin , where Safina went on to win the biggest title of her career . `` She 's a really tough opponent on this surface , '' Sharapova said . `` I came very close , but it did n't go my way for some reason . '' In other fourth round ties , Russian fourth seed Svetlana Kuznetsova was leading Belarussian 16th seed Victoria Azarenka 6-2 2-2 while Petra Kvitova of the Czech Republic and Estonia 's Kaia Kanepi were 3-6 6-3 when play was halted .