-LRB- CNN -RRB- -- Kyrgyzstan 's president signed a bill Friday to close an air base that the U.S. military uses as a route for troops and supplies heading into Afghanistan , the president announced on his Web site . Manas Air Base in Kyrgyzstan serves as a U.S. supply route for troops and supplies into Afghanistan . The news came as two other central Asian nations -- Tajikistan and Uzbekistan -- reportedly agreed to let U.S. cargo pass through their countries on the way to Afghanistan . Such deals , if confirmed , could help fill the void left by the closing of the Manas Air Base in Kyrgyzstan . The Kyrgyz order became effective on Friday when President Kurmanbek Bakiyev reportedly signed legislation that the parliament in Bishkek backed on Thursday , the Pentagon said . Pentagon spokesman Bryan Whitman said the Kyrgyz Foreign Ministry on Friday officially notified the U.S. Embassy in Bishkek that a 180-day withdrawal process is under way . Embassy spokeswoman Michelle Yerkin told CNN the United States hopes to retain the base . Officials in Washington and Bishkek signed a deal three years ago allowing the United States to renew the arrangement annually through July 2011 . `` We do remain in contact with the government of Kyrgyzstan , '' Yerkin said . `` The Manas Air Base continues to operate under existing agreements , as per the coalition 's efforts in Afghanistan . '' U.S. Defense Secretary Robert Gates said Friday the United States will continue to work with Kyrgyzstan on keeping the base open . Watch why Kyrgyzstan wants to close the base '' `` I continue to believe that this is not a closed issue and that there remains the potential at least to reopen this issue with the Kyrgyz and perhaps reach a new agreement , '' Gates said at a NATO meeting in Krakow , Poland . `` If we are unable to do that on reasonable terms then , as I have suggested , we are developing alternative methods to get resupply and people into Afghanistan . '' The Manas Air Base outside Bishkek is the only U.S. base in Central Asia and is a major resupply hub for the war in Afghanistan . Its closing could deal a significant blow to the U.S. military effort there , especially following President Barack Obama 's announcement of additional troops to halt a resurgence of the country 's former Taliban rulers . The United States pays $ 17.4 million a year to use Manas , a major logistical and refueling center that supports troops in Afghanistan , the Pentagon said . About 15,000 troops and 500 tons of cargo reportedly move through Manas monthly , it said . The air base currently employs more than 1,000 servicemen , 95 percent of whom are Americans , Russia 's Interfax news agency reported . `` This is an important facility , it has been an important facility , but it 's not irreplaceable and , if necessary , we will find other options , '' Whitman said . How far is Manas from Afghanistan ? View our map '' Tajikistan and Uzbekistan , two other Central Asian nations that border Afghanistan , have agreed to allow U.S. cargo to be transported to Afghanistan through their countries , the Russian news agency Interfax reported Friday . The agency said Rear Adm. Mark Harnitchek , U.S. transportation command director for strategy , policy , programs and logistics , held a meeting with Tajik Foreign Minister Kharokhon Zarifi , after which he said he had also secured Uzbekistan 's consent . A Tajik government statement said only that the two sides discussed the issue , but a spokesman for the Tajik foreign ministry told CNN that `` practically all issues '' to allow U.S. cargo transit through the country have been resolved . If confirmed , success would still depend on how much access the United States would have to those countries for flights and cargo , and even then , it may not totally replace the capacity lost in Kyrgyzstan . U.S. General David Petraeus , who oversees the war in Afghanistan , was in Uzbekistan this week for talks on Afghanistan and other regional issues . A Pentagon spokesman told CNN that his discussions included the regional supply network into Afghanistan . The U.S. military leased a base in Uzbekistan after the September 11 , 2001 , attacks on the United States . But after Uzbek troops were accused of killing at least 150 people during a demonstration in 2005 , the autocratic government of President Islam Karimov came under criticism from Washington and severed most of its military ties with the United States .