To study the effect of electroacupuncture with near-to-bone needling on the proliferation and apoptosis of knee osteoarthritis.
Totally 40 New Zealand rabbits were randomly divided into two groups, the normal group (A, 
HE stain demonstrated that the chondrocytes of A group,C group and D group were arranged in a more regular and smooth surface when compared with B group. The expressions of Bcl-2 and PCNA in C and D groups were higher than those of B group, but the expression of Caspase-3 and Bax were lower, when evaluated with Western blot;increased expressions of 
The electroacupuncture with near-to-bone needling method is superior to the electroacupuncture with ordinary needling in decreasing apoptosis and promoting proliferation of chondrocytes.