To explore the value of diagnosis with 99mTcO4- sequential scintigraphy of parotid gland in Sjögren's syndrome.
Technetium-99m(99mTcO4-) sequential scintigraphy was used in 52 cases of Sjögren's syndrome.
The results were analysed quantitatively with activity curve by using ROI computer program. 46 cases (88.46%) were parotid swelling. The contour was clear in 28 cases (53.85%) and blurred in 18 cases (34.62%). The function of parotid was normal in 7 cases (13.46%), parotids with light damage in 15 cases (28.84%), parotids with middle damage in 17 cases (32.69%), and parotids with serious damage in 13 cases (25%). Most cases of damaged secretary function was present in the early phase, and a few cases of damaged absorption function was found in the following process.
99mTcO4- sequential scintigraphy of parotid gland is greatly valuable to diagnosis of Sjögren's syndrome.