Lipocalin-type prostaglandin D synthase (L-PGDS) catalyzes the formation of prostaglandin D
Experimental OA was induced in wild-type (WT) and L-PGDS-deficient (L-PGDS
Compared to WT mice, L-PGDS
Collectively, these findings suggest a protective role of L-PGDS in OA, and therefore enhancing levels of L-PGDS may constitute a promising therapeutic strategy.