We examined the soluble CD23 (sCD23) molecules in sera and saliva from patients with Sjögren's syndrome.
The determination of sCD23 and other soluble molecules were made by the enzyme-linked immunosorbent assay.
The amounts of sCD23 in the sera/saliva were significantly increased in the patients compared to the controls and the levels were significantly correlated with sialoectasis.
The findings suggest that increased sCD23 molecules in saliva from patients with Sjögren's syndrome may reflect active sialoectasis.