Obesity is associated with worse disease activity and drug responses in patients with rheumatoid arthritis (RA). However, the immunological mechanisms responsible for the relationship between RA and obesity have not yet been clarified in detail. This study aimed to elucidate the immunological mechanisms contributing to the pathogenesis of RA in overweight patients.
The frequencies of CD4
The frequencies of T helper (Th)17 (CD4
Quantitative and qualitative changes in Th17 cells were characteristic in overweight patients with RA.