To investigated the association between single nucleotide polymorphisms (SNPs) in 
We systemically extracted the genetic data of 
The extracted genetic association data from three previous GWASs showed that the allele T of functional SNP rs2431697 increased RA susceptibility. The significant association for the SNP was also found in the Chinese replication cohort (OR = 1.24, 95% CI = 1.06-1.46, 
In summary, this study supports that genetic variant in 