Review of the literature addressing the rheumatic manifestations of various malignancies as well as of common chemotherapeutic agents.
A literature search was performed to identify key articles regarding the association of rheumatic disease with malignancy.
Our review focused on the association of rheumatic disease with malignancy, paraneoplastic syndromes with rheumatic manifestations, and chemotherapeutic agents related to rheumatic syndromes. We have discussed the importance of a newly described autoantibody that may identify patients at risk for malignancy associated myositis.
Based on our literature review, recommendations are suggested regarding who and how patients should be screened for malignancy when presenting with various rheumatic symptoms.