Total knee replacement (TKR) is an effective and cost-effective strategy for treating end-stage knee osteoarthritis. Greater risk for complications among TKR recipients with a body mass index (BMI) of 40 kg/m
To assess the value of TKR in recipients with a BMI of 40 kg/m
Osteoarthritis Policy Model to assess long-term clinical benefits, costs, and cost-effectiveness of TKR in patients with a BMI of 40 kg/m
Total knee replacement parameters from longitudinal studies and published literature, and costs from Medicare Physician Fee Schedules, the Healthcare Cost and Utilization Project, and published data.
Recipients of TKR with a BMI of 40 kg/m
Lifetime.
Health care sector.
Total knee replacement.
Cost, quality-adjusted life-years (QALYs), and incremental cost-effectiveness ratios (ICERs), discounted at 3% annually.
Total knee replacement increased QALYs by 0.71 year and lifetime medical costs by $25 200 among patients aged 50 to 65 years with a BMI of 40 kg/m
In TKR recipients with a BMI of 40 kg/m
Data are derived from several sources.
National Institute of Arthritis and Musculoskeletal and Skin Diseases of the National Institutes of Health.
From a cost-effectiveness perspective, TKR offers good value in patients with a BMI of 40 kg/m