To explore the specific mechanism of heat-reinforcing needling (HRN) for rheumatoid arthritis (RA) rabbits with cold syndrome based on metabolomics.
A total of 40 healthy rabbits were randomly divided into a normal group, a model group, a reinforcing-reducing needling(RRN) group, a twirling-reinforcing needling (TRN) group and a HRN group (
The pain threshold and the local skin temperature in the model group were lower than those in the normal group (
HRN for RA with cold syndrome is effective, which may be related to the specific regulation for the krebs cycle and glycometabolism.