The study of osteoarthrosis (OA) course in the region of goiter endemia regarding thyroid status.
The examination of 62 females with OA included enzyme immunoassay of blood TTH, T4, T3 and ultrasound investigation of the thyroid.
OA patients were found to have subnormal levels of thyroid hormones and low thyroid index. Blood TTH rose with thyroid size. Joint changes were also directly related to thyroid size.
Alterations in the thyroid status influence the course of degenerative-dystrophic process in the joints.