To report the first case of sarcoid-related uveitis in a patient receiving adalimumab.
Case report.
A 61-year-old woman with rheumatoid arthritis treated with adalimumab for 4 years presented with a 1-year history of bilateral panuveitis with venous vasculitis and peripheral multifocal choroiditis. A small papular lesion was found on her forehead, which upon biopsy showed noncaseating granulomas. No systemic involvement was observed.
An ophtalmological and clinical improvement was seen after (TNF) antagonist withdrawal plus a course of prednisone.
Ophthalmologists should know that a sarcoid-like granulomatosis can develop during TNFα blockade therapy.