Primary Sjögren's syndrome (SS) is a lymphoproliferative disease with a chronic autoimmune disorder characterized by mononuclear cell (MNC) infiltration of notably the lacrimal and salivary glands. As mesenchymal stem cells (MSCs) regulate series of immunological responses partially by regulating proportion of CD4
Potent immunosuppressive effects of human UC-MSCs on SS were explored 
In both protocols, the histopathology of submandibular and sublingual salivary glands showed decreased inflammatory infiltrates. 
Human UC-MSCs are capable of inducing CD4