Total iv MEQ were not significantly reduced during the PACU stay in patients receiving nicotine ( median -LSB- interquartile range ( IQR ) -RSB- , @ -LSB- @ , @ -RSB- mg for nicotine vs. @ -LSB- @ , @ -RSB- mg for placebo , one-tailed P = @ ) or for the first @ h following PACU discharge ( @ -LSB- @ , @ -RSB- mg for nicotine vs. @ -LSB- @ , @ -RSB- mg for placebo , one-tailed P = @ ) .