Participants received single , total doses of IR/ER HB/APAP @ / @ mg ( intact ; three active tablets ) and @/@ mg ( intact and crushed -LSB- encapsulated -RSB- ; six active tablets ) , IR HB/APAP @ / @ mg ( intact ; three active tablets ) and @/@ mg ( intact and crushed -LSB- encapsulated -RSB- ; six active tablets ) , and placebo .