The Saline v Albumin Fluid Evaluation ( SAFE ) trial reported patient-centred outcomes at @ days in @ patients assigned to fluid resuscitation with either @ % albumin or @ % saline ; the Crystalloid v Hydroxyethyl Starch Trial ( CHEST ) reported patient-centred outcomes at @ days in @ patients assigned to fluid resuscitation with either @ % HES ( @/@ @ ) or @ % saline .