Plasma glucagon levels ( AUC@-@h @,@ @ vs. @,@ @ ng/L/h , P = @ ) and lipolysis ( free fatty acid AUC@-@h @ @ vs. @ @ mmol/L/h , P = @ ; - OH-butyrate AUC@-@h @ @ vs. @ @ mmol/L/h , P = @ ; glycerol , P < @ ) were overall more suppressed after evening versus morning glargine administration .