In a double-blind , crossover trial , subjects with asthma who had BHR to inhaled mannitol ( n = @ ; @ men ; mean age , @ years ; one-half taking regular inhaled corticosteroids ) were randomized to omega-@ supplements ( @ g/d eicosapentaenoic acid and @ g/d docosahexaenoic acid ) or matching placebo for @ weeks separated by a @-week washout .