The point estimates ( PEs ) of the Test/Reference ( T/R ) adjusted geometric mean ratios of AUC ( @-last ) , AUC ( @ - ) , and C ( max ) were @ % , @ % , and @ % , respectively , and all of them showed @ % - confidence intervals ( CIs ) within the range of @ - @ % as suggested by regulatory requirements for bioequivalence assessment In total , @ subjects experienced @ AEs during the study , the most frequently reported AE , i.e. , headache , accounted for @ out of the total @ AEs ( @ % ) and no AEs of severe intensity were reported .