On week @ , the mean ( SD ) change in total Kupperman index score ( -@ -LSB- @ -RSB- ) from baseline to week @ ; the mean ( SD ) changes in individual scores for paresthesia ( -@ -LSB- @ -RSB- ) , insomnia ( -@ -LSB- @ -RSB- ) , irritability ( -@ -LSB- @ -RSB- ) , joint or muscle pain ( -@ -LSB- @ -RSB- ) , fatigue ( -@ -LSB- @ -RSB- ) , headache ( -@ -LSB- @ -RSB- ) , formication ( -@ -LSB- @ -RSB- ) , and sexual life ( -@ -LSB- @ -RSB- ) ; and the mean ( SD ) changes in total cholesterol ( -@ -LSB- @ -RSB- mmol/L ) and triglycerides ( -@ -LSB- @ -RSB- mmol/L ) were significantly higher in the intervention group than in the control group ( P < @ ) .