Carotid-femoral pulse wave velocity ( PWV ) was measured with aplanation tonometry ( Sphygmocor ) after @ ( W@ ) and @ weeks ( W@ ) of treatment by the single-pill combination valsartan-amlodipine ( @/@ mg , then @/@ mg ) or an atenolol-amlodipine combination ( @/@ mg , then @/@ mg ) in a prospective , randomized , parallel-groups multicenter trial with PROBE design .