Safety was the primary objective ; secondary objectives included standardized neurological assessments ( Friedreich Ataxia Rating Scale -LSB- FARS -RSB- , International Cooperative Ataxia Rating Scale -LSB- ICARS -RSB- , @-Hole Peg Test -LSB- @HPT -RSB- , Timed @-Foot Walk , Low-Contrast Letter Acuity ) , general functional status ( Activities of Daily Living ) , and cardiac assessments .