Of the IL-@-producing Bregs , CD@ ( + ) / CD@ ( high ) / CD@ ( high ) / CD@ ( + ) , CD@ ( + ) / CD@ ( high ) / CD@ ( high ) / CD@ ( + ) , CD@ ( + ) / CD@ ( high ) / CD@ ( high ) / CD@ ( + ) , and CD@ ( + ) / CD@ ( high ) / CD@ ( high ) / CD@ ( - ) had significant higher frequency in patients under belatacept treatment when compared with those under cyclosporine .