@ adult patients ( @-@ years ) with established insulin-dependent type @ diabetes and at least one diabetes-related autoantibody were enrolled and randomly assigned ( in a @:@:@:@ ratio , by computer-generated randomisation list , with block size four ) to placebo or IL@ at @ MIU/day , @ MIU/day , or @ MIU/day for a @-day course and were followed up for @ days .