Measurements were taken after each crossover arm including BP ( peripheral and central ) , adipokines ( inflammation markers and adiponectin ) , volume markers ( extracellular-to-intracellular -LSB- E/I -RSB- fluid ratio ; N-terminal pro-brain natriuretic peptide -LSB- NT-proBNP -RSB- ) , kidney function ( estimated Glomerular Filtration Rate -LSB- eGFR -RSB- ) and proteinuria ( urine protein-creatinine ratio -LSB- PCR -RSB- and albumin-creatinine ratio -LSB- ACR -RSB- ) .