Based on this assumption a novel treatment for tonal tinnitus - tailor-made notched music training ( TMNMT ) ( Proc Natl Acad Sci USA @:@ -@ , @ ; Ann N Y Acad Sci @:@ -@ , @ ; Frontiers Syst Neurosci @:@ , @ ) has been introduced and will be tested in this clinical trial on a large number of tinnitus patients .