Comparing intact tablets , the drug liking E ( max ) ( median -LSB- @ % CI -RSB- ) was significantly lower for IR/ER HB/APAP @/@ mg ( @ -LSB- @ , @ -RSB- ) than an equal dose of IR HB/APAP ( @ -LSB- @ , @ -RSB- ; difference , -@ -LSB- -@ , -@ -RSB- ; P < @ ) .