Common grade @-@ laboratory abnormalities and adverse events ( irrespective of association with study drug ) included thrombocytopenia ( @ -LSB- @ % -RSB- in the panobinostat group vs @ -LSB- @ % -RSB- in the placebo group ) , lymphopenia ( @ -LSB- @ % -RSB- vs @ -LSB- @ % -RSB- ) , diarrhoea ( @ -LSB- @ % -RSB- vs @ -LSB- @ % -RSB- ) , asthenia or fatigue ( @ -LSB- @ % -RSB- vs @ -LSB- @ % -RSB- ) , and peripheral neuropathy ( @ -LSB- @ % -RSB- vs @ -LSB- @ % -RSB- ) .