The proportion of patients achieving an overall response did not differ between treatment groups ( @ -LSB- @ % , @ % CI @-@ -RSB- for panobinostat vs @ -LSB- @ % , @-@ -RSB- for placebo ; p = @ ) ; however , the proportion of patients with a complete or near complete response was significantly higher in the panobinostat group than in the placebo group ( @ -LSB- @ % , @ % CI @-@ -RSB- vs @ -LSB- @ % , @-@ -RSB- ; p = @ ) .