6000563
A Minimum Description Length Approach to Statistical Shape Modelling
117576
Transforming pixel signatures into an improved metric space
Abstract We address the problem of using scale-orientation pixel signatures to characterise local structure in X-ray mammograms, though the method we report is of general application. When signatures are treated as vectors for statistical analysis, the Euclidean metric is not well behaved. We have previously described a Best Partial Match (BPM) metric that measures signature similarity more naturally, but at high computational cost. We present a method for transforming signatures into a new space in which Euclidean distance approximates BPM distance, allowing BPM distance to be estimated at low computational cost. The new space is constructed using multi-dimensional scaling. The nonlinear transformation between the old and new spaces is learned using support vector regression. We present experimental results for mammographic data.
17273589
Developing a Measure of Similarity between Pixel Signatures
Our previous work in computer-aided mammography has used scaleorientation pixel signatures that provide a rich description of local structure. We describe work using the transportation (`earth mover') algorithm to de ne a measure of similarity between two signatures that recognises similar structures whilst remaining robust to background variability and the presence of other structures. Speci cally, we investigate an un-normalised, normalised and novel best-partialmatching (BPM) approach to measuring this transportation distance and compare it with Euclidean distance. Receiver operating characteristic (ROC) methodology is used to compare performance and an example of clinical application is given. The BPM approach outperforms the other methods.
35191926
Automatic Extraction of the Face Identity-Subspace
Facial variation divides into a number of functional subspaces, and ensemblespecific variation. An improved method of measuring these is presented, within the space defined by an Appearance Model. Initial estimates of the subspaces (lighting, pose, identity and expression) are obtained by Principal Components Analysis on appropriate groups of faces. An expectationmaximization algorithm is applied to image codings to maximise the probability of coding across these non-orthogonal subspaces. Ensemble specific variation is then removed by measuring the spatial predictability of the eigenvectors excluding those which are less predictable than the ensemble. These procedures significantly enhance identity recognition for a disjoint test set.
9944487
Constrained Active Appearance Models
Active Appearance Models (AAMs) have been shown to be useful for interpreting images of deformable objects. Here we place the AAM matching algorithm in a statistical framework, allowing extra constraints to be applied. This enables the models to be combined with other methods of object location. We demonstrate how user interaction can be used to guide the search and give results of experiments showing the effect of constraints on the performance of model matching.
18409496
Building optimal 2D statistical shape models
Statistical shape models are used widely as a basis for segmenting and interpreting images. A major drawback of the approach is the need, during training, to establish a dense correspondence across a training set of segmented shapes. We show that model construction can be treated as an optimisation problem, automating the process and guaranteeing the effectiveness of the resulting models. This is achieved by optimising an objective function with respect to the correspondence. We use an information theoretic objective function that directly promotes desirable features of the model. This is coupled with an effective method of manipulating correspondence, based on reparameterising each training shape, to build optimal statistical shape models. The method is evaluated on several training sets of shapes, showing that it constructs better models than alternative approaches. q 2003 Elsevier B.V. All rights reserved.
3993976
A Software Framework for Creating Patient Specific Geometric Models from Medical Imaging Data for Simulation Based Medical Planning of Vascular Surgery
The primary purpose of vascular surgery is to restore blood flow to organs and tissues. Current methods of vascular treatment planning rely solely on diagnostic and empirical data to guide the decision-making process. This paper details a simulation-based medical planning system for cardiovascular disease that use computational methods to evaluate alternative surgical options prior to treatment using patient-specific models of the vascular system. A software framework, called Geodesic, is mtroduced that reduces the time required to build patient-specific models from medical imaging data from several weeks to less than one day.
8887048
Using a Soft Core in a SoC Design: Experiences with picoJava
Through our experience in synthesis, validation, test, and integration of the picoJava processor core in a system-on-chip (SoC) design we point out the challenges faced and issues to address in efficient reuse of a soft core.
13161464
Macroscopic traffic flow modelling and ramp metering control using Matlab/Simulink
Computer programs to simulate traffic flow offer an opportunity to evaluate new strategies for reducing delays, congestion, fuel consumption and pollution. This paper describes a Statistical Traffic Model or STM, which is based on accepted macro-modelling concepts, such as the conservation of vehicles and the fundamental traffic diagram. In this case, the model is constructed using the well known Matlab/Simulink™ software package, so providing an integrated approach for data processing, graphical presentation of data, control system design and macroscopic simulation in one straightforward to use, widely available environment. To illustrate the methodology, the STM is applied to a section of the M3/M27 Ramp Metering Pilot Scheme in the UK. This Highways Agency sponsored project, based in the Southampton area, utilises traffic lights at the on-ramp entrances to regulate access to the main carriageway of the motorway, in an attempt to maintain flow close to the capacity. The paper utilises the model to help design a locally-coordinated ramp metering algorithm, based on proportional-integral-plus (PIP) control methods. In this manner, the STM proves particularly valuable for the application of multi-objective optimisation techniques in the design of new traffic management systems.
207655806
Environmental time series analysis and forecasting with the Captain toolbox
The Data-Based Mechanistic (DBM) modelling philosophy emphasises the importance of parametrically efficient, low order, 'dominant mode' models, as well as the development of stochastic methods and the associated statistical analysis required for their identification and estimation. Furthermore, it stresses the importance of explicitly acknowledging the basic uncertainty in the process, which is particularly important for the characterisation and forecasting of environmental and other poorly defined systems. The paper focuses on a Matlab^(R) compatible toolbox that has evolved from this DBM modelling research. Based around a state space and transfer function estimation framework, Captain extends Matlab^(R) to allow, in the most general case, for the identification and estimation of a wide range of unobserved components models. Uniquely, however, Captain focuses on models with both time variable and state dependent parameters and has recently been implemented with the latest methodological developments in this regard. Here, the main innovations are: the automatic optimisation of the hyper-parameters, which define the statistical properties of the time variable parameters; the provision of smoothed as well as filtered parameter estimates; the robust and statistically efficient identification and estimation of both discrete and continuous time transfer function models; and the availability of various special model structures that have wide application potential in the environmental sciences.
33669607
Patient-Specific Operative Planning for Aorto-Femoral Reconstruction Procedures
Traditionally, a surgeon will select a procedure for a particular patient based on past experience for patients with a similar state of disease. The experience gained from this patient will be selectively used when treating the next patient with similar symptoms. In this work, a surgical planning system was developed enabling a vascular surgeon to create and test alternative operative plans prior to surgery for a given patient. One dimensional and three dimensional hemodynamic (i.e. blood flow) simulations were performed for rest and exercise for operative plans for two aorto-femoral bypass patients and compared with actual postoperative data. The information that can be obtained from one-dimensional (volume flow distribution and pressure losses) and three-dimensional (wall shear stress) hemodynamic simulation may be clinically relevant to vascular surgeons planning interventions.