30210949
Exact and approximate algorithms for unordered tree matching
We consider the problem of comparison between unordered trees, i.e., trees for which the order among siblings is unimportant. The criterion for comparison is the distance as measured by a weighted sum of the costs of deletion, insertion and relabel operations on tree nodes. Such comparisons may contribute to pattern recognition efforts in any field (e.g., genetics) where data can naturally be characterized by unordered trees. In companion work, we have shown this problem to be NP-complete. This paper presents an efficient enumerative algorithm and several heuristics leading to approximate solutions. The algorithms are based on probabilistic hill climbing and bipartite matching techniques. The paper evaluates the accuracy and time efficiency of the heuristics by applying them to a set of trees transformed from industrial parts based on a previously proposed morphological model. >
12680145
Finding Patterns in Three-Dimensional Graphs: Algorithms and Applications to Scientific Data Mining
Presents a method for finding patterns in 3D graphs. Each node in a graph is an undecomposable or atomic unit and has a label. Edges are links between the atomic units. Patterns are rigid substructures that may occur in a graph after allowing for an arbitrary number of whole-structure rotations and translations as well as a small number (specified by the user) of edit operations in the patterns or in the graph. (When a pattern appears in a graph only after the graph has been modified, we call that appearance "approximate occurrence.") The edit operations include relabeling a node, deleting a node and inserting a node. The proposed method is based on the geometric hashing technique, which hashes node-triplets of the graphs into a 3D table and compresses the label-triplets in the table. To demonstrate the utility of our algorithms, we discuss two applications of them in scientific data mining. First, we apply the method to locating frequently occurring motifs in two families of proteins pertaining to RNA-directed DNA polymerase and thymidylate synthase and use the motifs to classify the proteins. Then, we apply the method to clustering chemical compounds pertaining to aromatic compounds, bicyclicalkanes and photosynthesis. Experimental results indicate the good performance of our algorithms and high recall and precision rates for both classification and clustering.
11616193
Automatic Hierarchical Classification of Structured Deep Web Databases
We present a method that automatically classifies structured deep Web databases according to a pre-defined topic hierarchy. We assume that there are some manually classified databases, i.e., training databases, in every node of the topic hierarchy. Each training database is probed using queries constructed from the node titles of the topic hierarchy and the query result counts reported by the database are used to represent the content of the database. Hence, when adding a new database it can be probed by the same set of queries and classified to a node whose training databases are most similar to the new one. Specifically, a support vector machine classifier is trained on each internal node of the topic hierarchy with these training databases and the new database can be classified into the hierarchy top-down level by level. A feature extension method is proposed to create discriminant features. Experiments run on real structured Web databases collected from the Internet show that this classification method is quite accurate.
236203
New Techniques for DNA Sequence Classification
DNA sequence classification is the activity of determining whether or not an unlabeled sequence S belongs to an existing class C. This paper proposes two new techniques for DNA sequence classification. The first technique works by comparing the unlabeled sequence S with a group of active motifs discovered from the elements of C and by distinction with elements outside of C. The second technique generates and matches gapped fingerprints of S with elements of C. Experimental results obtained by running these algorithms on long and well conserved Alu sequences demonstrate the good performance of the presented methods compared with FASTA. When applied to less conserved and relatively short functional sites such as splice-junctions, a variation of the second technique combining fingerprinting with consensus sequence analysis gives better results than the current classifiers employing text compression and machine learning algorithms.
2286283
Query result ranking over e-commerce web databases
To deal with the problem of too many results returned from an E-commerce Web database in response to a user query, this paper proposes a novel approach to rank the query results. Based on the user query, we speculate how much the user cares about each attribute and assign a corresponding weight to it. Then, for each tuple in the query result, each attribute value is assigned a score according to its "desirableness" to the user. These attribute value scores are combined according to the attribute weights to get a final ranking score for each tuple. Tuples with the top ranking scores are presented to the user first. Our ranking method is domain independent and requires no user feedback. Experimental results demonstrate that this ranking method can effectively capture a user's preferences.
14900181
Unordered tree mining with applications to phylogeny
Frequent structure mining (FSM) aims to discover and extract patterns frequently occurring in structural data, such as trees and graphs. FSM finds many applications in bioinformatics, XML processing, Web log analysis, and so on. We present a new FSM technique for finding patterns in rooted unordered labeled trees. The patterns of interest are cousin pairs in these trees. A cousin pair is a pair of nodes sharing the same parent, the same grandparent, or the same great-grandparent, etc. Given a tree T, our algorithm finds all interesting cousin pairs of T in O(|T|/sup 2/) time where |T| is the number of nodes in T. Experimental results on synthetic data and phylogenies show the scalability and effectiveness of the proposed technique. To demonstrate the usefulness of our approach, we discuss its applications to locating co-occurring patterns in multiple evolutionary trees, evaluating the consensus of equally parsimonious trees, and finding kernel trees of groups of phylogenies. We also describe extensions of our algorithms for undirected acyclic graphs (or free trees).
1269749
Complexity-adaptive search algorithm for block motion estimation
We propose a complexity-adaptive fast block matching algorithm design strategy that allows the user to terminate the algorithm at any target computational complexity. Two complexity-adaptive techniques, frame level complexity allocation and block level complexity allocation, are developed to approach the global complexity-distortion optimization A buffer control strategy is proposed to dynamically adjust the target complexity of one frame. The predictive complexity-distortion benefit list (PCDB list) technique is employed to allocate the target complexity into each block. By these techniques, we modify the full-search block matching, three-step search, new three-step search, and four-step search to the complexity-adaptive algorithms. Experimental results show that the complexity-adaptive algorithms could achieve better performance than traditional fixed algorithms from the viewpoint of complexity-distoftion optimization.
16538539
Optimal jumper insertion for antenna avoidance under ratio upper-bound
Antenna effect may damage gate oxides during plasma-based fabrication process. The antenna ratio of total exposed antenna area to total gate oxide area is directly related to the amount of damage. Jumper insertion is a common technique applied at routing and post-layout stages to avoid and to fix the problems caused by the antenna effect. This paper presents an optimal algorithm for jumper insertion under the ratio upper-bound. It handles Steiner trees with obstacles. The algorithm us based on dynamic programming while works on free trees. The time complexity is O(alpha|V|2 ) and the space complexity is O(|V|2), where |V| is the number of nodes in the routing tree and a is a factor depending on how to find a non-blocked position on a wire for a jumper
14306866
Differences in gene expression between B-cell chronic lymphocytic leukemia and normal B cells: a meta-analysis of three microarray studies
MOTIVATION
A major focus of current cancer research is to identify genes that can be used as markers for prognosis and diagnosis, and as targets for therapy. Microarray technology has been applied extensively for this purpose, even though it has been reported that the agreement between microarray platforms is poor. A critical question is: how can we best combine the measurements of matched genes across microarray platforms to develop diagnostic and prognostic tools related to the underlying biology?


RESULTS
We introduce a statistical approach within a Bayesian framework to combine the microarray data on matched genes from three investigations of gene expression profiling of B-cell chronic lymphocytic leukemia (CLL) and normal B cells (NBC) using three different microarray platforms, oligonucleotide arrays, cDNA arrays printed on glass slides and cDNA arrays printed on nylon membranes. Using this approach, we identified a number of genes that were consistently differentially expressed between CLL and NBC samples.
2380687
Packet classification using multidimensional cutting
This paper introduces a classification algorithm called phHyperCuts. Like the previously best known algorithm, HiCuts, HyperCuts is based on a decision tree structure. Unlike HiCuts, however, in which each node in the decision tree represents a hyperplane, each node in the HyperCuts decision tree represents a k--dimensional hypercube. Using this extra degree of freedom and a new set of heuristics to find optimal hypercubes for a given amount of storage, HyperCuts can provide an order of magnitude improvement over existing classification algorithms. HyperCuts uses 2 to 10 times less memory than HiCuts optimized for memory, while the worst case search time of HyperCuts is 50--500% better than that of HiCuts optimized for speed. Compared with another recent scheme, EGT-PC, HyperCuts uses 1.8--7 times less memory space while the worst case search time is up to 5 times smaller. More importantly, unlike EGT-PC, HyperCuts can be fully pipelined to provide one classification result every packet arrival time, and also allows fast updates.
37966786
Analysis of soft handoff algorithms with dynamic spreading WCDMA system
The undergoing 3G wireless network needs to support integration of voice and multimedia data services with varying QoS requirements. It is critical that the least BER for voice traffic, WWW traffic, and streaming video traffic be guaranteed at all time. With the capability of dynamically changing spreading factor, CDMA system could provide a range of QoS fitting the needs for different traffic type. In this paper, we extend our dynamic spreading admission control scheme to a multi-cell situation, by proposing a dynamic spreading enable soft handoff framework. The static system behavior is analyzed through the studying of the updating probability for both handoff mobile and target cell. Our analysis shows that the updating probability varies according the traffic of interest. A general expression of the joint updating probability is given assuming an equal distribution of traffic type. The processing time of the handoff request is analyzed. We found that the update process caused by handoff is the major component of delay. Further investigation shows that the update associated with handoff might consume too much access channel time, and increase the delay of handoff, especially when handoff traffic is heavy. We therefore adopt a batch mechanism such that multiple handoff requests could be processed simultaneously. The average delay is reduced from 1.12 seconds to 800 ms in heavy handoff rate.