3193955
An Improved Biclustering Method for Analyzing Gene Expression Profiles
Microarrays are one of the latest breakthroughs in experimental molecular biology, which provide a powerful tool by which the expression patterns of thousands of genes can be monitored simultaneously and are already producing huge amount of valuable data. The concept of bicluster was introduced by Cheng and Church1 to capture the coherence of a subset of genes and a subset of conditions. A set of heuristic algorithms were also designed to either find one bicluster or a set of biclusters, which consist of iterations of masking null values and discovered biclusters, coarse and fine node deletion, node addition, and the inclusion of inverted data. These heuristics inevitably suffer from some serious drawback. The masking of null values and discovered biclusters with random numbers may result in the phenomenon of random interference which in turn impacts the discovery of high quality biclusters. To address this issue and to further accelerate the biclustering process, we generalize the model of bicluster to incorporate null values and propose a probabilistic algorithm (FLOC) that can discover a set of k possibly overlapping biclusters simultaneously. Furthermore, this algorithm can easily be extended to support additional features that suit different requirements at virtually little cost. Experimental study on the yeast gene expression data2 shows that the FLOC algorithm can offer substantial improvements over the previously proposed algorithm.
11841640
Accelerating Profile Queries in Elevation Maps
Elevation maps are a widely used spatial data representation in geographical information systems (GIS). Paths on elevation maps can be characterized by profiles, which describe relative elevation as a function of distance. In this research, we address the inverse of this mapping - given a profile, how to efficiently find paths that could have generated it. This is called the profile query problem. Profiles have a wide variety of uses that include registering tracking information, or even other maps, to a given map. We describe a probabilistic model to characterize the maximal likelihood that a point lying on a path matches the query profile. Propagation of such probabilities to neighboring points can effectively prune the search space. This model enables us to efficiently answer queries of arbitrary profiles with user-specified error tolerances. When compared to existing spatial index methods, our approach supports more flexible queries with orders of magnitude speedup.
28890
Extension of Lower Probabilities and Coherence of Belief Measures
Coherence is an important concept which is introduced and discussed in a new mathematics branch, Imprecise Probability Theory. By using the Choquet integral, belief measures can be extended to be coherent lower previsions on the linear space consisting of all bounded functions. As a special case, we establish that all belief measures are coherent imprecise probabilities.
14969897
Dynamic adaptive file management in a local area network
In light of advances in processor and networking technology, especially the emergence of network attached disks, the traditional client-server architecture of file systems has become suboptimal for many computation/data intensive applications. We introduce a revised architecture for file management employing network attached storage: the dynamic file server environment (Dynamo). Dynamo introduces two main architectural innovations: to provide high scalability, the file management functions are mainly performed cooperatively by the clients in the system. Furthermore, data is transferred directly to the client's cache from network-attached disks, thus avoiding copies from a disk to the server buffer and then over the network to the client. Secondly, Dynamo uses a cooperative cache management which employs a decentralized lottery-based page replacement strategy. We show via performance benchmarks run on the Dynamo system and simulation results how this architecture increases the system's adaptability, scalability and cost performance.
19868872
Management Assistance for Work First via a Dynamic Website
The purpose of the Work First project is to assist the state Dept. of Health and Human Services (DHHS) staff and each county Dept. of Social Services (DSS) across the state in the management of welfare reform initiatives. Work First is the cash assistance program in NC. One important objective is to encourage and support program managers to use data on outcomes to assess their performance. This is accomplished by providing them with easy to use and easy to understand comprehensive information on the experiences of families and individuals that have received assistance through their agency over time.
62615149
Mining Asynchronous Periodic Patterns in Time Series Data
Periodicy detection in time series data is a challenging problem of great importance in many applications. Most previous work focused on mining synchronous periodic patterns and did not recognize the misaligned presence of a pattern due to the intervention of random noise. In this paper, we propose a more flexible model of asynchronous periodic pattern that may be present only within a subsequence and whose occurrences may be shifted due to disturbance. Two parameters min/spl I.bar/rep and max/spl I.bar/dis are employed to specify the minimum number of repetitions that is required within each segment of nondisrupted pattern occurrences and the maximum allowed disturbance between any two successive valid segments. Upon satisfying these two requirements, the longest valid subsequence of a pattern is returned. A two-phase algorithm is devised to first generate potential periods by distance-based pruning followed by an iterative procedure to derive and validate candidate patterns and locate the longest valid subsequence. We also show that this algorithm cannot only provide linear time complexity with respect to the length of the sequence but also achieve space efficiency.
14663639
An Effective Method to Improve Convergence for Sequential Blind Source Separation
Based on conventional natural gradient algorithm (NGA) and equivariant adaptive separation via independence algorithm (EASI), a novel sign algorithm for on-line blind separation of independent sources is presented. A sign operator for the adaptation of the separation model is obtained from the derivation of a generalized dynamic separation model. A variable step-size sign algorithm rooted in NGA is also derived to better match the dynamics of the input signals and unmixing matrix. The proposed algorithms are appealing in practice due to their computational simplicity. Experimental results verify the superior convergence performance over conventional NGA and EASI algorithm in both stationary and non-stationary environments.
9657581
k-anycast game in selfish networks
Conventionally, the majority of network routing protocols assume that every network terminal or link forwards data for others without any deviation. However, this may not be true when the terminals or links are owned by individual selfish users, who always tries to maximize their own benefits instead of faithfully following a prescribed protocol. In this paper, we propose a new routing protocol, called k-anycast routing, that works well even if network links (or terminals or both) are selfish. In our protocol, the source node first finds a tree that spans k receivers out of a set of possible receivers and pay the relay links to compensate their costs. We prove that every relay link follows the routing protocol: it maximizes its profit when it declares its actual cost
44902530
The 2-dipath chromatic number of Halin graphs
11973783
Answering Approximate Range Aggregate Queries on OLAP Data Cubes with Probabilistic Guarantees
Approximate range aggregate queries are one of the most frequent and useful kinds of queries for Decision Support Systems (DSS). Traditionally, sampling- based techniques have been proposed to tackle this problem. However, its effectiveness will degrade when the underlying data distribution is skewed. Another approach based on the outlier management can limit the effect of data skew but fails to address other requirements of approximate range aggregate queries, such as error guarantees and query processing efficiency. In this paper, we present a technique that provide approximate answers to range aggregate queries on OLAP data cubes efficiently with theoretical error guarantees. Our basic idea is to build different data structures for outliers and the rest of the data. Experimental results verified the effectiveness of our proposed methods.
49675441
Real-time rendering of plant leaves
This paper presents a framework for the real-time rendering of plant leaves with global illumination effects. Realistic rendering of leaves requires a sophisticated appearance model and accurate lighting computation. For leaf appearance we introduce a parametric model that describes leaves in terms of spatially-variant BRDFs and BTDFs. These BRDFs and BTDFs, incorporating analysis of subsurface scattering inside leaf tissues and rough surface scattering on leaf surfaces, can be measured from real leaves. More importantly, this description is compact and can be loaded into graphics hardware for fast run-time shading calculations, which are essential for achieving high frame rates. For lighting computation, we present an algorithm that extends the Precomputed Radiance Transfer (PRT) approach to all-frequency lighting for leaves. In particular, we handle the combined illumination effects due to low-frequency environment light and high-frequency sunlight. This is done by decomposing the local incident radiance of sunlight into direct and indirect components. The direct component, which contains most of the high frequencies, is not pre-computed with spherical harmonics as in PRT; instead it is evaluated on-the-fly using pre-computed light-visibility convolution data. We demonstrate our framework by the rendering of a variety of leaves and assemblies thereof.