206580995
Discovering compact and highly discriminative features or combinations of drug activities using support vector machines
Nowadays, high throughput experimental techniques make it feasible to examine and collect massive data at the molecular level. These data, typically mapped to a very high dimensional feature space, carry rich information about functionalities of certain chemical or biological entities and can be used to infer valuable knowledge for the purposes of classification and prediction. Typically, a small number of features or feature combinations may play determinant roles in functional discrimination. The identification of such features or feature combinations is of great importance. In this paper, we study the problem of discovering compact and highly discriminative features or feature combinations from a rich feature collection. We employ the support vector machine as the classification means and aim at finding compact feature combinations. Comparing to previous methods on feature selection, which identify features solely based on their individual roles in the classification, our method is able to identify minimal feature combinations that ultimately have determinant roles in a systematic fashion. Experimental study on drug activity data shows that our method can discover descriptors that are not necessarily significant individually but are most significant collectively.
11841640
Accelerating Profile Queries in Elevation Maps
Elevation maps are a widely used spatial data representation in geographical information systems (GIS). Paths on elevation maps can be characterized by profiles, which describe relative elevation as a function of distance. In this research, we address the inverse of this mapping - given a profile, how to efficiently find paths that could have generated it. This is called the profile query problem. Profiles have a wide variety of uses that include registering tracking information, or even other maps, to a given map. We describe a probabilistic model to characterize the maximal likelihood that a point lying on a path matches the query profile. Propagation of such probabilities to neighboring points can effectively prune the search space. This model enables us to efficiently answer queries of arbitrary profiles with user-specified error tolerances. When compared to existing spatial index methods, our approach supports more flexible queries with orders of magnitude speedup.
14969897
Dynamic adaptive file management in a local area network
In light of advances in processor and networking technology, especially the emergence of network attached disks, the traditional client-server architecture of file systems has become suboptimal for many computation/data intensive applications. We introduce a revised architecture for file management employing network attached storage: the dynamic file server environment (Dynamo). Dynamo introduces two main architectural innovations: to provide high scalability, the file management functions are mainly performed cooperatively by the clients in the system. Furthermore, data is transferred directly to the client's cache from network-attached disks, thus avoiding copies from a disk to the server buffer and then over the network to the client. Secondly, Dynamo uses a cooperative cache management which employs a decentralized lottery-based page replacement strategy. We show via performance benchmarks run on the Dynamo system and simulation results how this architecture increases the system's adaptability, scalability and cost performance.
28890
Extension of Lower Probabilities and Coherence of Belief Measures
Coherence is an important concept which is introduced and discussed in a new mathematics branch, Imprecise Probability Theory. By using the Choquet integral, belief measures can be extended to be coherent lower previsions on the linear space consisting of all bounded functions. As a special case, we establish that all belief measures are coherent imprecise probabilities.
19868872
Management Assistance for Work First via a Dynamic Website
The purpose of the Work First project is to assist the state Dept. of Health and Human Services (DHHS) staff and each county Dept. of Social Services (DSS) across the state in the management of welfare reform initiatives. Work First is the cash assistance program in NC. One important objective is to encourage and support program managers to use data on outcomes to assess their performance. This is accomplished by providing them with easy to use and easy to understand comprehensive information on the experiences of families and individuals that have received assistance through their agency over time.
62615149
Mining Asynchronous Periodic Patterns in Time Series Data
Periodicy detection in time series data is a challenging problem of great importance in many applications. Most previous work focused on mining synchronous periodic patterns and did not recognize the misaligned presence of a pattern due to the intervention of random noise. In this paper, we propose a more flexible model of asynchronous periodic pattern that may be present only within a subsequence and whose occurrences may be shifted due to disturbance. Two parameters min/spl I.bar/rep and max/spl I.bar/dis are employed to specify the minimum number of repetitions that is required within each segment of nondisrupted pattern occurrences and the maximum allowed disturbance between any two successive valid segments. Upon satisfying these two requirements, the longest valid subsequence of a pattern is returned. A two-phase algorithm is devised to first generate potential periods by distance-based pruning followed by an iterative procedure to derive and validate candidate patterns and locate the longest valid subsequence. We also show that this algorithm cannot only provide linear time complexity with respect to the length of the sequence but also achieve space efficiency.
12623712
A transparent rate adaptation algorithm for streaming video over the Internet
The lack of end-to-end quality of service support in the current Internet has caused significant difficulties to ensuring playback continuity in video streaming applications. This study addresses this challenge by investigating a new adaptation algorithm to adjust the bit-rate of video data in response to the network bandwidth available to improve playback continuity. Unlike previous works, the proposed algorithm is transparent to the video client, requires no parameter tuning, and yet can outperform existing algorithms. This paper presents this algorithm, evaluates and compares its performance with the best algorithm currently available using extensive trace-driven simulations.
1993887
Locating Motifs in Time-Series Data
Finding motifs in time-series is proposed to make clustering of time-series subsequences meaningful, because most existing algorithms of clustering time-series subsequences are reported meaningless in recent studies. The existing motif finding algorithms emphasize the efficiency at the expense of quality, in terms of the number of time-series subsequences in a motif and the total number of motifs found. In this paper, we formalize the problem as a continuous top-k motif balls problem in an m-dimensional space, and propose heuristic approaches that can significantly improve the quality of motifs with reasonable overhead, as shown in our experimental studies.
42677463
Heterogeneous software reliability modeling
A number of Markov-based software reliability models have been developed for measuring software reliability. However, the application of these models is strictly limited to software that satisfies the Markov properties. The objective of our work is to expand the application domain of the Markov-based models, so that most software can be modeled and software reliability can be measured at the architecture level. To overcome the limitations of Markov properties, our model takes execution history into account and addresses both deterministic and probabilistic software behaviors. Each state represents the executions of one or more components depending on the architectural styles. In addition, the executions of one component are depicted by using distinctive states, when such executions are influenced by past states. Furthermore, we construct loops to eliminate the likelihood of unlimited state expansion and utilize a binomial tree structure to account for all the different execution paths. We show that Markov models are applicable even to software that does not fully satisfy the Markov properties. Therefore, we significantly improve the state of the art in architecture-based software reliability modeling.
18265885
Identifying intrusions in computer networks with principal component analysis
Most current anomaly intrusion detection systems (IDSs) detect computer network behavior as normal or abnormal but cannot identify the type of attacks. Moreover, most current intrusion detection methods cannot process large amounts of audit data for real-time operation. In this paper, we propose a novel method for intrusion identification in computer networks based on principal component analysis (PCA). Each network connection is transformed into an input data vector. PCA is employed to reduce the dimensionality of the data vectors and identification is handled in a low dimensional space with high efficiency and low use of system resources. The normal behavior is profiled based on normal data for anomaly detection and models of each type of attack are built based on attack data for intrusion identification. The distance between a vector and its reconstruction onto those reduced subspaces representing the different types of attacks and normal activities is used for identification. The method is tested with network data from MIT Lincoln labs for the 1998 DARPA intrusion detection evaluation program and testing results show that the model is promising in terms of identification accuracy and computational efficiency for real-time intrusion identification.
16100691
Design multicast protocols for non-cooperative networks
Conventionally, most network protocols assume that the network entities that participate in the network activities will always behave as instructed. However, in practice, most network entities will try to maximize their own benefits instead of altruistically contribute to the network by following the prescribed protocols, which is known as selfish. Thus, new protocols should be designed for the non-cooperative network, which is composed of selfish entities. In this paper, we specifically show how to design strategyproof multicast protocols for non-cooperative networks such that these selfish entities will follow the protocols out of their own interests. By assuming that a group of receivers is willing to pay to receive the multicast service, we specifically give a general framework to decide whether it is possible, and how if possible to transform an existing multicast protocol to a strategyproof multicast protocol. We then show how the payments to those relay entities are shared fairly among all receivers so that it encourages collaboration among receivers. As a running example, we show how to design the strategyproof multicast protocol for the currently used core-based multicast structure. We also conduct extensive simulations to study the relations between payment and cost of the multicast structure.