16232707
A weighted sum validity function for clustering with a hybrid niching genetic algorithm
Clustering is inherently a difficult problem, both with respect to the construction of adequate objective functions as well as to the optimization of the objective functions. In this paper, we suggest an objective function called the Weighted Sum Validity Function (WSVF), which is a weighted sum of the several normalized cluster validity functions. Further, we propose a Hybrid Niching Genetic Algorithm (HNGA), which can be used for the optimization of the WSVF to automatically evolve the proper number of clusters as well as appropriate partitioning of the data set. Within the HNGA, a niching method is developed to preserve both the diversity of the population with respect to the number of clusters encoded in the individuals and the diversity of the subpopulation with the same number of clusters during the search. In addition, we hybridize the niching method with the k-means algorithm. In the experiments, we show the effectiveness of both the HNGA and the WSVF. In comparison with other related genetic clustering algorithms, the HNGA can consistently and efficiently converge to the best known optimum corresponding to the given data in concurrence with the convergence result. The WSVF is found generally able to improve the confidence of clustering solutions and achieve more accurate and robust results.
39184835
Improved Robustness in Time Series Analysis of Gene Expression Data by Polynomial Model Based Clustering
Microarray experiments produce large data sets that often contain noise and considerable missing data. Typical clustering methods such as hierarchical clustering or partitional algorithms can often be adversely affected by such data. This paper introduces a method to overcome such problems associated with noise and missing data by modelling the time series data with polynomials and using these models to cluster the data. Similarity measures for polynomials are given that comply with commonly used standard measures. The polynomial model based clustering is compared with standard clustering methods under different conditions and applied to a real gene expression data set. It shows significantly better results as noise and missing data are increased.
40113853
A Framework for Modelling Short, High-Dimensional Multivariate Time Series: Preliminary Results in Virus Gene Expression Data Analysis
Short, high-dimensional Multivariate Time Series (MTS) data are common in many fields such as medicine, finance and science, and any advance in modelling this kind of data would be beneficial. Nowhere is this more true than functional genomics where effective ways of analysing gene expression data are urgently needed. Progress in this area could help obtain a "global" view of biological processes, and ultimately lead to a great improvement in the quality of human life. We present a computational framework for modelling this type of data, and report preliminary experimental results of applying this framework to the analysis of gene expression data in the virology domain. The framework contains a threestep modelling strategy: correlation search, variable grouping, and short MTS modelling. Novel research is involved in each step which has been individually tested on different real-world datasets in engineering and medicine. This is the first attempt to integrate all these components into a coherent computational framework, and test the framework on a very challenging application area, which has produced promising results.
6104018
A framework for modelling virus gene expression data
Short, high-dimensional, Multivariate Time Series (MTS) data are common in many fields such as medicine, finance and science, and any advance in modelling this kind of data would be beneficial. Nowhere is this truer than functional genomics where effective ways of analysing gene expression data are urgently needed. Progress in this area could help obtain a “global” view of biological processes, and ultimately lead to a great improvement in the quality of human life. We present a computational framework for modelling this type of data, and report experimental results of applying this framework to the analysis of gene expression data in the virology domain. The framework contains a three-step modelling strategy: correlation search, variable grouping, and short MTS modelling. Novel research is involved in each step which has been individually tested on different real-world datasets in engineering and medicine. This is the first attempt to integrate all these components into a coherent computational framework, and test the framework on a very challenging application area, producing promising results.
14510898
Evolutionary learning of dynamic probabilistic models with large time lags
In this paper, we explore the automatic explanation of multivariate time series (MTS) through learning dynamic Bayesian networks (DBNs). We have developed an evolutionary algorithm which exploits certain characteristics of MTS in order to generate good networks as quickly as possible. We compare this algorithm to other standard learning algorithms that have traditionally been used for static Bayesian networks but are adapted for DBNs in this paper. These are extensively tested on both synthetic and real-world MTS for various aspects of efficiency and accuracy. By proposing a simple representation scheme, an efficient learning methodology, and several useful heuristics, we have found that the proposed method is more efficient for learning DBNs from MTS with large time lags, especially in time-demanding situations. © 2001 John Wiley & Sons, Inc.
16058917
Learning Dynamic Bayesian Networks from Multivariate Time Series with Changing Dependencies
Many examples exist of multivariate time series where dependencies between variables change over time. If these changing dependencies are not taken into account, any model that is learnt from the data will average over the different dependency structures. Paradigms that try to explain underlying processes and observed events in multivariate time series must explicitly model these changes in order to allow non-experts to analyse and understand such data. In this paper we have developed a method for generating explanations in multivariate time series that takes into account changing dependency structure. We make use of a dynamic Bayesian network model with hidden nodes. We introduce a representation and search technique for learning such models from data and test it on synthetic time series and real-world data from an oil refinery, both of which contain changing underlying structure. We compare our method to an existing EM-based method for learning structure. Results are very promising for our method and we include sample explanations, generated from models learnt from the refinery dataset.
7272374
Opportunistic transmission scheduling with resource-sharing constraints in wireless networks
We present an "opportunistic" transmission scheduling policy that exploits time-varying channel conditions and maximizes the system performance stochastically under a certain resource allocation constraint. We establish the optimality of the scheduling scheme and also that every user experiences a performance improvement over any nonopportunistic scheduling policy when users have independent performance values. We demonstrate via simulation results that the scheme is robust to estimation errors and also works well for nonstationary scenarios, resulting in performance improvements of 20%-150% compared with a scheduling scheme that does not take into account channel conditions. Last, we discuss an extension of our opportunistic scheduling scheme to improve "short-term" performance.
10662727
Power macromodeling of global interconnects considering practical repeater insertion
In this paper, we present a simple yet highly effective power macromodeling technique for global interconnects that considers optimal repeater insertion. Specifically,our model estimates the interconnect power dissipation from the interconnect length, the timing budget, the repeater location flexibility, and the signal activity using an analytical function that is derived for a given repeater library and fabrication technology. In experiments with different standard cell libraries, the average error of our technique is less than 2%.
3266821
A Least Biased Fuzzy Clustering Method
A new operational definition of cluster is proposed, and a fuzzy clustering algorithm with minimal biases is formulated by making use of the maximum entropy principle to maximize the entropy of the centroids with respect to the data points (clustering entropy). The authors make no assumptions on the number of clusters or their initial positions. For each value of an adimensional scale parameter /spl beta/', the clustering algorithm makes each data point iterate towards one of the cluster's centroids, so that both hard and fuzzy partitions are obtained. Since the clustering algorithm can make a multiscale analysis of the given data set one can obtain both hierarchy and partitioning type clustering. The relative stability with respect to /spl beta/' of each cluster structure is defined as the measurement of cluster validity. The authors determine the specific value of /spl beta/' which corresponds to the optimal positions of cluster centroids by minimizing the entropy of the data points with respect to the centroids (clustered entropy). Examples are given to show how this least biased method succeeds in getting perceptually correct clustering results. >
5155570
Low-power repeater insertion with both delay and slew rate constraints
In this paper, a novel repeater insertion algorithm is presented to minimize the power dissipation of interconnect trees under given timing budgets and slew rate constraints. In contrast to traditional bottom-up dynamic programming approaches, the proposed algorithm combines a Lagrangian relaxation framework and a graph-based search method to derive possible solutions in a top-down fashion. As a result, it is capable of analyzing repeater slew rates efficiently. In addition, our scheme incorporates accurate circuit models and is therefore able to capture the precise delay and slew rate information, leading to high-quality interconnect designs. We have applied our scheme to interconnects of different topologies and various timing and slew rate constraints. Experimental results demonstrate the effectiveness of our approach in comparison with previous low-power repeater insertion schemes. Under tight timing constraints, our scheme can always derive repeater insertion solutions that meet both delay and slew rate requirements, whereas other schemes often fail. Under loose timing constraints, our algorithm achieves up to a 23% average power dissipation reduction for different interconnects specifications with shorter runtimes
292448
Efficient Network Utilization for Multimedia Wireless Networks
In this paper, we present an access scheme to satisfy the QoS requirements for two classes of traffic during the contention phase of packet-switched wireless communications. In the proposed scheme, difierent classes of users contend with other users for resources based on controlled class-dependent permission probabilities. We prove that our algorithm is stable for a large class of arrival processes. Under certain QoS requirements, we derive an upper-bound on the throughput for a general class of random access algorithms. We show that the throughput of our algorithm asymptotically approaches this upper-bound. We also show, through numerical examples, that our algorithm achieves high network utilization.