15545886
Dimensionality reduction via discretization
The existence of numeric data and large numbers of records in a database present a challenging task in terms of explicit concepts extraction from the raw data. The paper introduces a method that reduces data vertically and horizontally, keeps the discriminating power of the original data, and paves the way for extracting concepts. The method is based on discretization (vertical reduction) and feature selection (horizontal reduction). The experimental results show that (a) the data can be effectively reduced by the proposed method; (b) the predictive accuracy of a classifier (C4.5) can be improved after data and dimensionality reduction; and (c) the classification rules learned are simpler.
14543078
Resource description framework: metadata and its applications
Universality, the property of the Web that makes it the largest data and information source in the world, is also the property behind the lack of a uniform organization scheme that would allow easy access to data and information. A semantic web, wherein different applications and Web sites can exchange information and hence exploit Web data and information to their full potential, requires the information about Web resources to be represented in a detailed and structured manner. Resource Description Framework (RDF), an effort in this direction supported by the World Wide Web Consortium, provides a means for the description of metadata which is a necessity for the next generation of interoperable Web applications. The success of RDF and the semantic web will depend on (1) the development of applications that prove the applicability of the concept, (2) the availability of application interfaces which enable the development of such applications, and (3) databases and inference systems that exploit RDF to identify and locate most relevant Web resources. In addition, many practical issues, such as security, ease of use, and compatibility, will be crucial in the success of RDF. This survey aims at providing a glimpse at the past, present, and future of this upcoming technology and highlights why we believe that the next generation of the Web will be more organized, informative, searchable, accessible, and, most importantly, useful. It is expected that knowledge discovery and data mining can benefit from RDF and the Semantic Web.
5365583
NeuroRule: A Connectionist Approach to Data Mining
Classification, which involves finding rules that partition a given da.ta set into disjoint groups, is one class of data mining problems. Approaches proposed so far for mining classification rules for large databases are mainly decision tree based symbolic learning methods. The connectionist approach based on neura.l networks has been thought not well suited for data mining. One of the major reasons cited is that knowledge generated by neural networks is not explicitly represented in the form of rules suitable for verification or interpretation by humans. This paper examines this issue. With our newly developed algorithms, rules which are similar to, or more concise than those generated by the symbolic methods can be extracted from the neural networks. The data mining process using neural networks with the emphasis on rule extraction is described. ExperimenM results and comparison with previously published works are presented.
8367210
Sensor Sequence Modeling for Driving
Intelligent systems in automobiles need to be aware of the driving and driver context. Available sensor data stream has to be modeled and monitored in order to do so. Currently there exist no building blocks for hierarchical modeling of driving. By semi-supervised segmentation such building blocks can be discovered. We call them drivemes in analogy to phonemes. More parsimonious modeling of driving becomes now possible.
16386059
A Monotonic Measure for Optimal Feature Selection
Feature selection is a problem of choosing a subset of relevant features. In general, only exhaustive search can bring about the optimal subset. With a monotonic measure, exhaustive search can be avoided without sacrificing optimality. Unfortunately, most error- or distancebased measures are not monotonic. A new measure is employed in this work that is monotonic and fast to compute. The search for relevant features according to this measure is guaranteed to be complete but not exhaustive. Experiments are conducted for verification.
46794790
Analysis of Hidden Representations by Greedy Clustering
The hidden layer of backpropagation neural networks (NNs) holds the key to the networks' success in solving pattern classification problems. The units in the hidden layer encapsulate the network's internal representations of the outside world described by the input data. this paper, the hidden representations of trained networks are investigated by means simple greedy clustering algorithm. This clustering algorithm is applied to networks have been trained to solve well-known problems: the monks problems, the 5-bit problem and the contiguity problem. The results from applying the algorithm to problems with known concepts provide us with a better understanding of NN learning. These also explain why NNs achieve higher predictive accuracy than that of decision-tree methods. The results of this study can be readily applied to rule extraction from Production rules are extracted for the parity and the monks problems, as well as benchmark data set: Pima Indian diabetes diagnosis. The extracted rules from the Indi...
9642703
Discovering typical structures of documents: a road map approach
The structure of a document refers to the role and hierarchy of subdocument references. Many online documents are similarly structured, though not identically structured. We study the problem of discovering “typical” structures of a collection of such documents, where the user specifies the minimum frequency of a typical structure. We will consider structural features of subdocument references such as labeling, nesting, ordering, cyclicity, and wild-card references, like those found on the Web and digital libraries. Typical structures can be used to serve the following purposes. (a) The “table-ofcontent” for gaining the general information of a source. (b) A road map for browsing and querying a source. (c) A basis for clustering documents. (d) Partial schemas for building structured layers to provide standard database access methods. (e) User/customer’s interests and browsing patterns. We present a solution to the discovery problem.
36964410
A Knowledge Object Oriented System for High Throughput Collection and Analysis of Data
3172606
Gene name ambiguity of eukaryotic nomenclatures
MOTIVATION
With more and more scientific literature published online, the effective management and reuse of this knowledge has become problematic. Natural language processing (NLP) may be a potential solution by extracting, structuring and organizing biomedical information in online literature in a timely manner. One essential task is to recognize and identify genomic entities in text. 'Recognition' can be accomplished using pattern matching and machine learning. But for 'identification' these techniques are not adequate. In order to identify genomic entities, NLP needs a comprehensive resource that specifies and classifies genomic entities as they occur in text and that associates them with normalized terms and also unique identifiers so that the extracted entities are well defined. Online organism databases are an excellent resource to create such a lexical resource. However, gene name ambiguity is a serious problem because it affects the appropriate identification of gene entities. In this paper, we explore the extent of the problem and suggest ways to address it.


RESULTS
We obtained gene information from 21 organisms and quantified naming ambiguities within species, across species, with English words and with medical terms. When the case (of letters) was retained, official symbols displayed negligible intra-species ambiguity (0.02%) and modest ambiguities with general English words (0.57%) and medical terms (1.01%). In contrast, the across-species ambiguity was high (14.20%). The inclusion of gene synonyms increased intra-species ambiguity substantially and full names contributed greatly to gene-medical-term ambiguity. A comprehensive lexical resource that covers gene information for the 21 organisms was then created and used to identify gene names by using a straightforward string matching program to process 45,000 abstracts associated with the mouse model organism while ignoring case and gene names that were also English words. We found that 85.1% of correctly retrieved mouse genes were ambiguous with other gene names. When gene names that were also English words were included, 233% additional 'gene' instances were retrieved, most of which were false positives. We also found that authors prefer to use synonyms (74.7%) to official symbols (17.7%) or full names (7.6%) in their publications.


CONTACT
lifeng.chen@dbmi.columbia.edu
11306780
Mean-entropy discretized features are effective for classifying high-dimensional biomedical data
This paper studies an empirical feature selection heuristics for classifying high-dimensional bio-medical data. A feature's discriminating power can be measured by its entropy value. Based on this idea, we do not consider those features that are ignored by the entropy idea. Such a selection can usually reduce the dimensionality of the data by 90-95%. Then we rank the remaining features, and select features whose entropy is smaller than the average of all the remaining features' entropies. This round of selection can usually further reduce two thirds of the features. So, we can achieve a reduction from tens of thousands of features to only hundreds of important features. Furthermore, we also observe that learning algorithms, including our new tree-committee classifier, generally improve their accuracy after the feature selection. This heuristics appears to be more systematic than the prevailing use of specific numbers of top-ranked features for classification.
11034725
Data Mining Tools for Biological Sequences
We describe a methodology, as well as some related data mining tools, for analyzing sequence data. The methodology comprises three steps: (a) generating candidate features from the sequences, (b) selecting relevant features from the candidates, and (c) integrating the selected features to build a system to recognize specific properties in sequence data. We also give relevant techniques for each of these three steps. For generating candidate features, we present various types of features based on the idea of k-grams. For selecting relevant features, we discuss signal-to-noise, t-statistics, and entropy measures, as well as a correlation-based feature selection method. For integrating selected features, we use machine learning methods, including C4.5, SVM, and Naive Bayes. We illustrate this methodology on the problem of recognizing translation initiation sites. We discuss how to generate and select features that are useful for understanding the distinction between ATG sites that are translation initiation sites and those that are not. We also discuss how to use such features to build reliable systems for recognizing translation initiation sites in DNA sequences.