Lack of Osmosensitive CD9 Expression in Rat Liver Cells
CD9 mRNA was found to be strongly expressed in H4IIE rat hepatoma cells and rat liver macrophages (Kupffer cells), whereas the expression was weak in primary rat liver parenchymal cells. An osmosensitive regulation of CD9 mRNA levels was not detectable in all three cell types, whereas this has recently been described for MadinDarby canine kidney cells and rabbit renal papillary cells (see text). The findings suggest that osmoregulation of specific genes may exhibit cell type specificity.