Determination of Pyrethroid Pesticides in Estuarine and Coastal Sediments by Accelerated Solvent Extraction and Liquid Chromatography-Tandem Mass Spectrometry
A rapid and accurate method was developed for the measurement of 12 pyrethroid pesticides in estuarine and coastal sediments by accelerated solvent extraction(ASE) and liquid chromatography-tandem mass spectrometry (LC-MS/MS).The pyrethroid pesticides were extracted in 5.0 min and repeated one more time by ASE using mixed solvent of n-hexane and acetone(1:1,V/V) at 60 ℃ and pressure of 10.3 MPa with static extraction mode.After concentrated,the pesticides were separated with XDB-C18 column with mobile phase of methanol and water containing 2.5 mmol/L ammonium acetate,and then determined with tandem mass spectrometer using positive ESI at MRM mode.Under the optimized conditions,relative standard deviation(RSD) for developed method was 1.1%-8.6%(20.0 μg/kg,n=8),standard added recoveries were 67.9%-97.3%,and the limits of quantification(LOQ,10 σ) were 0.5-2.5 μg/kg.