Study on the synthesis of α-tocopherol oleate
To present the process development of α- tocopherol oleate synthesis by orthogonal design experiments in which α-tocopherol reacted with oleic chloride catalyzed by triethy lamine. The optimum conditions were as following, at 45℃, the rate of α-tocopherol and oleic chloride(mol/mol)=1∶2.5, in the presence of 0.1mL/g α-tocopherol triethy lamine as catalyst, the esterification of α-tocopherol could exeed 54.87% after 5 hours of reaction.