Comparison on dissolution rate of dehy-droandrogrpholide
Objective: To investigate the effect of the ultra-fine powder on dissolution rates of dehy-droandrogrpholide. Method: The dissolution rates of dehy-droandrogrpholide from the normal and ultra-fine powder of Andrographis were detected with SPE-HPLC techniques. Result: The dissolution rates of dehydroandrogrpholide from the ultra-micro powder was higher than that from the normal powder, but there was no difference after 40 mins. Conclusion: The dissolution velocity of dehydroandrogrpholide are greatly increased and there is not loss of the components in ultra-micro powder.