Electrochemiluminescence of Sodium Dodecyl Sulfate-Verapamil Hydrochloride-Ru(bpy)_3~(2+) System and Its Application
When [SDS] was 0.3125 mmol/L,the electrochemical and ECL behaviours of Ru(bpy)32+-verapamil hydrochloride(yswlpm) system at the Au electrode were studied.An enhancement electrochemical activity and ECL response were exhibited in the presence of SDS.Base on this,ECL method was established for the determination of verapamil hydrochloride.Under the optimum experimental conditions,the ECL intensities had good linear relationship with the concentration of the verapamil hydrochloride in the range of 1.0×10-4-1.0×10-7 mol/L(r=0.9958).The detection limit was 5.2×10-10 mol/L.The RSD for 5 times determination of 1.0×10-5 mol/L verapamil hydrochloride was 3.1%.The results of recovery were between 98.7%-106.5%,the RSD for 5 times was 3.0%.This proposed method showed high selectivity and sensitivity,and the sensitivity,and the disposal method of the sample was simple.