Reaction of 3-aminoindole-2-carboxylic acids with diethyl acetylenedicarboxylate
Abstractδ-Carboline and indolo-δ-carboline derivatives were obtained by reaction of the potassium salts of 3-aminoindole-2-carboxylic acids with diethyl acetylenedicarboxylate. A difference in the behavior of 3-aminoindole derivatives in the Michael reaction due to the nature of the substituent in the 5 position of the indole ring was established.