Combination Therapy with Valsartan Plus Bailing Capsule for Chronic Kidney Disease
Objective To study the effect and rationality of treating chronic kidney disease using combination therapy of valsartan plus Bailing capsule.Methods 56 patients with chronic kidney disease were randomly divided into control group (n=27, only giving valsartan) and treating group (n=29, giving valsartan combination with Bailing capsule), Control group were given valsartan 80mg/d, and were given 160mg/d after one week, Treating group were above dose valsartan plus Bailing capsule 3.0g/d, Before given above treatment, serum creatinine (Scr), Creatinine clearance (Ccr), urinary protein excretion were measure. Then Scr, Ccr and urinary protein excretion were measured at the end of 4th and 12th weeks.Results Scr both treating group and control group increased at the end of 4th weeks, but no more increase from then on. Ccr both two group weren't significantly different(P0.05). Urinary protein excretion both two group were significantly decreased after treating 4th weeks, and were more significantly decreased compared to that at the 12th week(P0.05).At the same time, urinary protein excretion of treating group were more significantly decreased than that of control group(P0.05).Conclusion Urine protein can be decreases regardless of treating with valsartan only or treating with valsartan combined Bailing Capsule on chronic kidney disease. And the effect of latter therapy is better than former.