Optimization of the technology condition for ultra high pressure extraction Coreopsis basalis total flavonoids by response surface method
With the yeild of Coreopsis flavonoids as index, the preparation process of ultra-high pressure (UHP) on extraction total flavonoids from Coreopsis basalis was optimized according to Box-Behnken central composition design principle, the method of response surface analysis with 3 factors and 3 levels combined with Minitab15.0-statistical data analysis software was adopted. According to the above results, the optimum extraction conditions were obtained as follows: ratio of solid to liquid l:16(g/mL), pressure 340 MPa, material particles 80 mesh, holding time 3 min, and under this condition, the yeild of Coreopsis flavonoids was up to 12.35%.