Promoting effects of 6-Gingerol on probiotic adhesion to colonic epithelial cells
Intestinal probiotics are mixture of microorganisms which have beneficial effects on the health of the host by adjusting balance of intestinal flora, including preventing the occurrence of intestinal inflammatory diseases and stimulating the beneficial effects of probiotics in the gut system (Huang et al., 2014). Several studies have demonstrated that probiotics could inhibit the growth of harmful bacteria and strengthen the intestinal mucosal barrier of host (Bao et al., 2010; Kotzamanidis et al., 2010; Vázquez-Fresno et al., 2014; Liu et al., 2016). Meanwhile, probiotic adhesion is an essential prerequisite for physiological functions of probiotics (Zhang, 2019; Li et al., 2011; Wang et al., 2019; Bai et al., 2012). So promoting the probiotic adhesion would strengthen the beneficial effects of probiotics. It has been reported that some natural foods and their extracts such as apple extracts (peel and pulp) and their phenolic constituents increased the adhesion of two probiotics strains to intestinal epithelial cells (Volstatova et al., 2017).