Electrophilic substitution in benzo[b]furo[2,3-c]pyridines: nitration, acylation
It has been shown that the nitration and acylation of substituted benzo[b]furo[2,3-c]pyridines proceeds exclusively at position 6 of the benzene ring. If position 6 is blocked by a substitutnt, the product of monosubstitution at the C(8) atom is formed. The molecules that were investigated have been calculated in the MNDO approximation.