Comparison of the effects of protein and polysaccharide from oat on blood glucose and lipids in diabetic model mice by alloxan
Objective: Comparison of the effects of protein and polysaccharides from oat on blood glucose and lipids in diabetic model mice by alloxan. Methods: The mice model with diabetes was established through the injection of alloxan. Both diabetic model mice and normal mice were treated with the same doses of oat protein and polysaccharide, and set up a normal control group and diabetic model group. At the same time, the mice body weight and blood glucose value were observed and recorded. After 15 days, the serum was obtained from retro-orbital blood drawn from anesthetized mice for the analysis of the GLU, CHOL, TG and HDL levels. Results: Both oat protein and polysaccharide all had the hypoglycemiceffects on diabetic mice, but oat polysaccharide was more obvious. And they could maintain the TG at a relatively low level, but the effect of oat polysaccharide to improve the content of CHOL and HDL to tent to normal values was more than oat protein. Conclusion: The effection that oat polysaccharide controlled blood glucose of diabetic mice was faster and more obvious than protein. Oat protein was more prominent in improving the CHOL and HDL than polysaccharide.