Synthesis of ethyl Β-(2,2 -dimethyltetrahydro-4-pyranyl)-Β-oxopropionate
The acylation of carbethoxymethylenetriphenylphosphorane with 2,2-dimethyltetrahydropyran-4-carboxylic acid chloride and subsequent pyrolysis of the resulting ylid lead to the formation of ethyl 2,2-diniethyltetrahydro-4-pyranylpropiolate, the hydration of which gives the corresponding Β-keto ester.