Synthesis of Citronellyl Acetate via a Transacetylation to Citronellol from Acetyl Coenzyme A Produced from Glucose and Acetate in Growing Yeasts
A novel coupling system, which is an acetylation system of primary alcohols with acetyl coenzyme A [acetyl-CoA] formed via the metabolism of glucose and acetate, was developed with Hansenula and Pichia. The supplementation of sodium acetate to glucose as the source of acetyl-CoA was effective to enhance the reaction rate and yield of acetylation of citronellol.