Cancer diagnosis at early stage using serum derivative fluorescence emission spectra
Abstract First-order derivative fluorescence emission spectroscopy was proposed to screen cancer at early stage. Wistar rat were inoculated with sarcoma. After extracting their serum with ethanol, the intensities of fluorescence band (630 nm) of supernatants were measured with first-order derivative fluorescence emission spectrometry. An obvious contrast between healthy and diseased serum could be observed, and diagnosis of malignant tumors at early stage could be achieved. No false negative samples were found in all ten cancer samples, but only one healthy sample was false positive.