Correlation between intestinal microbiota and immune response to vaccination
Intestinal microbiota plays an important role in the development of immune system, especially in the formation of immune response. Immune response to vaccination varies with region and population, which may be related to the differences in intestinal microbiota. This review focused on the correlation between intestinal microbiota and immune response to vaccination in order to find a new way to enhance vaccine-induced immune response. It was revealed that intestinal microbiota might be involved in the immune responses to vaccines against rotavirus, typhoid and polio. Although probiotics, prebiotics and synbiotics could not significantly enhance vaccine-induced immune response, they might have a beneficial effect on vaccine by regulating intestinal microbiota. 
 
 
Key words: 
Intestinal tract; Microbiota; Vaccine; Immune response