Determination of Sulfadiazine in Water by Solid Phase Extraction and High Performance Liquid Chromatography
The experiment condition of SPE and high performance liquid chromatography about sulfadiazine was researched,and its operation conditions were optimized. A SPE-high performance liquid chromatography method for the residues determination of sulfadiazine in water was established. The regression equation of the standard sulfadiazine curve is y=0.0576x+1.3448.The linearity range is 10～250ng/mL. The correlation coefficient is 0.9969. The limits of quantification is 5ng/mL for sulfadiazine. The average recovery for sulfadiazine is 91.66%～94.45% .The relative standard deviation is 1.7%～3.5%.