Zika virus: An update review
Zika virus (ZIKV) was first isolated in 1947. It is known to circulate mainly in tropical areas and can be transmitted through Aedes mosquitoes. In 2015, an outbreak of ZIKV began in Brazil and then spread rapidly to the Latin Americans and Caribbean. Accumulating evidence indicates that there are associations between ZIKV infection and human nervous disorders, such as the occurrence of microcephaly in neonates and Guillain-Barre syndrome in adults. The current ZIKV outbreak has been declared a public health emergency of international concern. Here, we review the virological features, transmission and epidemiological characteristics of ZIKV and the clinical featrues and prevention of ZIKV infection. 
 
 
Key words: 
Zika virus; Outbreak; Aedes mosquitoes; Arthropod-borne virus; Microcephaly; Guillain-Barre syndrome