QUAKING REGULATION OF VISCERAL ENDODERM FUNCTION IS REQUIRED FOR VASCULAR REMODELING AND RETINOIC ACID-MEDIATED CONTROL OF ENDOTHELIAL CELL PROLIFERATION
markedly reduced following over-expression of ILK-KD compared to control infected cells (5.1 + 0.8 fold) and similar findings were observed endothelial cells. VCAM-1 activates endothelial cell NADPH oxidase in minutes and stimulates lymphocyte matrix metalloproteinase (MMP) activafter 72 hr (52.0 + 6.8%, n = 3). Furthermore, expression of proliferating cell nuclear antigen levels was reduced to 35.2 + 1.7% of RAd LacZ control levels, after 24 hr. Wounding assays illustrated VSMC migration was