[The criteria of early detection of biotinidase deficiency-based epilepsy].
OBJECTIVE An analysis of clinical and paraclinical symptomatology of three cases of infant epilepsy due to biotinidase deficiency is presented. MATERIAL AND METHODS The diagnosis took 4 months in the first case and 1 day in the last one. RESULTS AND CONCLUSION It is emphasized that early diagnosisbased on knowing the reference signs of this inherited metabolic disease provides an opportunity to avoid patient's disability or death.