Synthesis and structure of asymmetric 2,4,6-triazidopyridines
The reactions of 3-cyanotetrafluoropyridine and tetrachloro-3-trifluoromethylpyridine with sodium azide lead to the corresponding 2,4,6-triazido-5-cyano-3-fluoropyridine and 2,4,6-triazido-5-chloro-3-trifluoromethylpyridine. With the aid of comparative X-ray structural analysis of 2,4,6-triazido-5-cyano-3-fluoropyridine and its previously known 3-chloro-substituted derivative it was established that the geometric parameters and reactivity of the azide groups in the asymmetric 2,4,6-triazi-dopyridines depend not only on the position of these groups in the pyridine ring but also on their mutual orientation in space.