[Effects of nicotinamide on sinoatrial conduction time and sinus node recovery time in rabbit hearts].
The effects of nicotinamide (Nic) on sinoatrial conduction time (SACT) and sinoatrial node recovery time (SNRT) were studied in anesthetized rabbits and the isolated sinoatrial preparation of rabbit hearts by right atrium pacing techniques. In vivo, SNRT and corrected sinoatrial node recovery time (SNRTc) were markedly shortened after Nic administration (0.6 g/kg, iv) 12% (p 0.05).