A NEW ROUTE TO 3,7-DIMETHYL-2,6-OCTADIEN-1-OL AND 3,7-DIMETHYL-2-OCTENE-1,7-DIOL FROM ISOPRENE
A convenient synthetic method for 3,7-dimethyl-2,6-octadien-1-ol (1) (geraniol and nerol) and 3,7-dimethyl-2-octene-1,7-diol (2), involving the anionic telomerization of isoprene and the rearrangement of amine oxide was established. The overall yields of (1) and (2) (E/Z ratio=2) from isoprene were 61 and 44%, respectively.