A facile synthesis of diformylated pyrroles by dehydroxylation of N-aryl-5-hydroxy-γ-lactam derivatives under Vilsmeier reaction conditions
A simple and efficient methodology for the conversion of substituted trans-1,4-diaryl-5-hydroxypyrrolidin-2-ones to diformylated N-arylpyrroles by treatment with Vilsmeier–Haack reagent has been developed.