CRYSTAL STRUCTURES OF PERMETHYLATED α-CYCLODEXTRIN COMPLEXES WITH L- AND D-MANDELIC ACIDS
The crystal structures of permethylated α-cyclodextrin complexes with L- and D-mandelic acids were determined by the X-ray method. The host molecule of the L-mandelic acid complex, having a pseudo two-fold symmetry, loosely includes the phenyl group, while the hydroxyl and carboxyl groups form hydrogen bonds with water molecules located outside the host cavity. D-Mandelic acid is tightly bound within the host cavity, forming a host–guest hydrogen bond.