Effects of apparatus on age-related impairement of novel-object recognition in Kunming mice
The effects of different apparatus,i.e.,Y-shape,square and rectangle boxs,on age-related impairement of memory in novel-object recognition task in Kunming mice were explored,respectively.The results indicated that there were no age-related changes in the 10-minute-delay trial in each of apparatus.During the 24 hours delay trial,the ability of novel-object recognition in the 21-month mice decreased in the Y-shape box compared to the 6-month and 12-month mice,and in the square box compared to the 12-month mice,with being mainly attributable to females.The data measured in the Y-shape box were more stable than that in the others.These results suggested that there was age-related impairement of long-term memory of novel-object recognition in the female Kunming mice,and the Y-shape box was the suitable apparatus for detection of this impairement.