Effects of black garlic on life-span and antioxidation in UV-damaged Drosophila Melanogaster
Objective: To explore the effect of black garlic on the life-span and antioxidation in ultravioletdamaged Drosophila Melanogaster. Methods: The male Drosophila at 2 d aged were divided randomly into 5 groups, control group(0 mg/mL, UV radiation 0 min), model group(0 mg/mL, UV radiation 40 min), dose groups(15 mg/mL, 30 mg/mL, 60 mg/mL, UV radiation 40 min) of black garlic. In life-span study, dead flies were counted every 3 days until all flies died, the mean life span, maximum span and 50% survival time were calculated. In antioxidation study, the SOD activity, CAT activity and MDA content of flies were measured for the effect of black garlic after 18 days treated. Results: The results showed that black garlic could improve the average life span and maximum life of UV-damaged Drosophila Melanogaster. The activities of SOD and CAT was increased with the decreasing of MDA content at the same time. Conclusion: It was concluded that the antioxidant effect of black garlic in Drosophila Melanogaster maintained on an ultraviolet-damaged was accompanied by up-regulation of CAT and SOD with the decreasing of MDA.