Current Concepts of Neurocytoprotective Therapy
This review addressed the pharmacological effects and clinical efficacies of one of the “oldest” neurocytoprotective agents – Cerebrolysin. Experimental data identifying the molecular mechanisms of action of this agent are described in detail, along with results from clinical trials demonstrating the efficacy of Cerebrolysin in the treatment of acute and chronic cerebral ischemia, Alzheimer’s disease, and moderate and mild cognitive disorders. It is concluded that Cerebrolysin is an effective agent as demonstrated from the point of view of basic research (including in animal models and cell cultures) and numerous clinical trials in a variety of pathological states.