Condensed imidazo-1,2,4-azines 22. Alkylation of 5H-imidazo[1,2-b]-1,2,4-triazepin-4-ones
Substituted 5H-imidazo[1,2-b]-1,2,4-triazepin-4-ones react with alkyl (alkenyl) halides, 2-chloroethanol, glycerin dichlorohydrin, haloacetic acids, the methyl ester and amide of monochloroacetic acid in a methanol-sodium methylate system to form N(5)-alkylation products, and with hydroxylamino-O-sulfonic acid to form 5-aminoimidazo[1,2-b]-1,2,4-triazepin-4-one.