muscle biomechanical
5996231
Mechanics without muscle: biomechanical inspiration from the plant world.
Plant and animal biomechanists have much in common. Although their frame of reference differs, they think about the natural world in similar ways. While researchers studying animals might explore airflow around flapping wings, the actuation of muscles in arms and legs, or the material properties of spider silk, researchers studying plants might explore the flow of water around fluttering seaweeds, the grasping ability of climbing vines, or the material properties of wood. Here we summarize recent studies of plant biomechanics highlighting several current research themes in the field: expulsion of high speed reproductive projectiles, generation of slow movements by shrinking and swelling cell walls, effects of ontogenetic shifts in mechanical properties of stems, flexible reconfiguration and material properties of seaweeds under crashing waves, and the development of botanically inspired commercial products. Our hope is that this synopsis will resonate with both plant and animal biologists, encourage cross pollination across disciplines, and promote fruitful interdisciplinary collaborations in the future.
Integrative and comparative biology
Patrick T Martone Michael L Boller Ingo Burgert Jacques Dumais Joan E Edwards Katharine J Mach Nick P Rowe Markus Rueggeberg Robin Seidel Thomas Speck
3370318
Shear wave sonoelastography of skeletal muscle: basic principles, biomechanical concepts, clinical applications, and future perspectives
Imaging plays an important role in the diagnosis and therapeutic response evaluation of muscular diseases. However, one important limitation is its incapacity to assess the in vivo biomechanical properties of the muscles. The emerging shear wave sonoelastography technique offers a quantifiable spatial representation of the viscoelastic characteristics of skeletal muscle. Elastography is a non invasive tool used to analyze the physiologic and biomechanical properties of muscles in healthy and pathologic conditions. However, radiologists need to familiarize themselves with the muscular biomechanical concepts and technical challenges of shear wave elastography. This review introduces the basic principles of muscle shear wave elastography, analyzes the factors that can influence measurements and provides an overview of its potential clinical applications in the field of muscular diseases.
Skeletal Radiology
Maud Creze Antoine Nordez Marc Soubeyrand Laurence Rocher Xavier Maitre Marie France Bellin
13886393
Androgen deprivation causes selective deficits in the biomechanical leg muscle function of men during walking: a prospective case control study
Although muscle mass declines with testosterone deficiency in men, previous studies of muscle function have not demonstrated consistent deficits, likely due to relatively insensitive methodology. Our objective was to determine the effects of testosterone deprivation on the biomechanical function of individual lower limb muscles.
Journal of cachexia, sarcopenia and muscle
Ada S Cheung Hans A Gray Anthony G Schache Rudolf Hoermann Daryl Lim Joon Jeffrey D Zajac Marcus G Pandy Mathis Grossmann
9422918
Relationship between recovery of calf muscle biomechanical properties and gait pattern following surgery for achilles tendon rupture.
BACKGROUND The relationship between ankle plantar flexor biomechanical properties and gait pattern following surgery for acute rupture of the Achilles tendon has not yet been fully investigated. METHODS Forty nine young adults (27 men and 22 women) who underwent surgical repair of a complete Achilles tendon rupture were evaluated at 3, 6, 12 and 24 months by clinical assessment, biomechanical evaluation and gait analysis. FINDINGS Ankle range of motion, plantar flexor passive stiffness and concentric strength were recovered within 12 months. Gait abnormalities related to these factors took longer to disappear owing to the presence of anomalous muscle patterns. At 24 months, a deficit in calf muscle eccentric strength was still present, determining adaptive changes in gait strategy that involved ankle motion and coordinated muscular activity. INTERPRETATION Improvement of gait pattern is slower than recovery of plantar flexor mechanical properties. Persisting mechanical impairment resulting in gait adaptations may be detrimental to the healing structures by increasing stress on the Achilles tendon. Restoration of calf muscle eccentric strength and coordinated antagonist muscle activity should be key points in postoperative rehabilitation following surgical repair of Achilles tendon rupture.
Clinical biomechanics
Romildo Don Alberto Ranavolo Angelo Cacchio Mariano Serrao Francesca Costabile Massimo Iachelli Filippo Camerota Massimo Frascarelli Valter Santilli
1171435
A real time system for biomechanical analysis of human movement and muscle function
Mechanical analysis of movement plays an important role in clinical management of neurological and orthopedic conditions. There has been increasing interest in performing movement analysis in real time, to provide immediate feedback to both therapist and patient. However, such work to date has been limited to single joint kinematics and kinetics. Here we present a software system, named human body model (HBM) to compute joint kinematics and kinetics for a full body model with 44 degrees of freedom, in real time, and to estimate length changes and forces in 300 muscle elements. HBM was used to analyze lower extremity function during gait in 12 able bodied subjects. Processing speed exceeded 120 samples per second on standard PC hardware. Joint angles and moments were consistent within the group, and consistent with other studies in the literature. Estimated muscle force patterns were consistent among subjects and agreed qualitatively with electromyography, to the extent that can be expected from a biomechanical model. The real time analysis was integrated into the D Flow system for development of custom real time feedback applications and into the gait real time analysis interactive lab system for gait analysis and gait retraining.
Medical Biological Engineering Computing
Anton J van den Bogert Thomas Geijtenbeek Oshri Even-Zohar Frans Steenbrink Elizabeth C Hardin
28752423
Noncontact quantitative biomechanical characterization of cardiac muscle using shear wave imaging optical coherence tomography.
We report on a quantitative optical elastographic method based on shear wave imaging optical coherence tomography (SWI OCT) for biomechanical characterization of cardiac muscle through noncontact elasticity measurement. The SWI OCT system employs a focused air puff device for localized loading of the cardiac muscle and utilizes phase sensitive OCT to monitor the induced tissue deformation. Phase information from the optical interferometry is used to reconstruct 2 D depth resolved shear wave propagation inside the muscle tissue. Cross correlation of the displacement profiles at various spatial locations in the propagation direction is applied to measure the group velocity of the shear waves, based on which the Young's modulus of tissue is quantified. The quantitative feature and measurement accuracy of this method is demonstrated from the experiments on tissue mimicking phantoms with the verification using uniaxial compression test. The experiments are performed on ex vivo cardiac muscle tissue from mice with normal and genetically altered myocardium. Our results indicate this optical elastographic technique is useful as a noncontact tool to assist the cardiac muscle studies.
Biomedical optics express
Shang Wang Andrew L Lopez Yuka Morikawa Ge Tao Jiasong Li Irina V Larina James F Martin Kirill V Larin
35667573
Flexibility, muscle strength and running biomechanical adaptations in older runners.
BACKGROUND The increased injury risk in older runners has been associated with alterations in muscle strength, flexibility, and gait biomechanics. This study investigated whether older runners exhibit changes in muscle strength, flexibility and running biomechanics compared to younger runners, and possible relationships between these changes. METHODS Thirty five young (20 36yrs) and 35 older (55 71yrs) recreational runners participated in the study. Measures of three dimensional biomechanical data during treadmill running at 2.7m/s and measures of muscle strength and flexibility were compared between groups. A correlation analysis between biomechanical and clinical variables was also performed. FINDINGS Older runners demonstrated an overall reduction in muscle strength and flexibility, and altered running patterns compared to young runners but correlations between clinical and biomechanical variables were scarce. Reduced hip, ankle and trunk excursions along with reduced knee and ankle positive work were found in older runners. Older runners also exhibited increased knee abduction impulse, ankle abduction impulse and vertical loading rates. In contrast, older runners did not present a distal to proximal lower extremity joint moment redistribution. INTERPRETATION We observed age related reduced strength and flexibility concomitant with alterations in running biomechanics, but a lack of correlation between these variables. This finding hampers the use of single, or even a subset of characteristics to better understand age related changes in runners. The observed changes are complex and multivariate in nature. Clinicians will most likely have to monitor both clinical and biomechanical characteristics to optimize care. However, future studies need to prospectively address what are biomechanical age related risk factors in runners.
Clinical biomechanics
Reginaldo Kisho Fukuchi Darren John Stefanyshyn Lisa Stirling Marcos Duarte Reed Ferber
8588144
WHAT IS A MOMENT ARM? CALCULATING MUSCLE EFFECTIVENESS IN BIOMECHANICAL MODELS USING GENERALIZED COORDINATES.
Biomechanics researchers often use multibody models to represent biological systems. However, the mapping from biology to mechanics and back can be problematic. OpenSim is a popular open source tool used for this purpose, mapping between biological specifications and an underlying generalized coordinate multibody system called Simbody. One quantity of interest to biomechanical researchers and clinicians is "muscle moment arm," a measure of the effectiveness of a muscle at contributing to a particular motion over a range of configurations. OpenSim can automatically calculate these quantities for any muscle once a model has been built. For simple cases, this calculation is the same as the conventional moment arm calculation in mechanical engineering. But a muscle may span several joints (e.g. wrist, neck, back) and may follow a convoluted path over various curved surfaces. A biological joint may require several bodies or even a mechanism to accurately represent in the multibody model (e.g. knee, shoulder) In these situations we need a careful definition of muscle moment arm that is analogous to the mechanical engineering concept, yet generalized to be of use to biomedical researchers. Here we present some biomechanical modeling challenges and how they are resolved in OpenSim and Simbody to yield biologically meaningful muscle moment arms.
Proceedings of the ASME Design Engineering Technical Conferences. ASME Design Engineering Technical Conferences
Michael A Sherman Ajay Seth Scott L Delp
40652412
Biomechanical Aspects of the Muscle Bone Interaction
There is growing interest in the interaction between skeletal muscle and bone, particularly at the genetic and molecular levels. However, the genetic and molecular linkages between muscle and bone are achieved only within the context of the essential mechanical coupling of the tissues. This biomechanical and physiological linkage is readily evident as muscles attach to bone and induce exposure to varied mechanical stimuli via functional activity. The responsiveness of bone cells to mechanical stimuli, or their absence, is well established. However, questions remain regarding how muscle forces applied to bone serve to modulate bone homeostasis and adaptation. Similarly, the contributions of varied, but unique, stimuli generated by muscle to bone (such as low magnitude, high frequency stimuli) remains to be established. The current article focuses upon the mechanical relationship between muscle and bone. In doing so, we explore the stimuli that muscle imparts upon bone, models that enable investigation of this relationship, and recent data generated by these models.
Current Osteoporosis Reports
Keith G Avin Susan A Bloomfield Ted S Gross Stuart J Warden
22019022
The relationships between muscle strength, biomechanical functional moments and health related quality of life in non elite older adults.
OBJECTIVE to investigate the association between muscle strength, biomechanical functional moments during everyday tasks and health related quality of life (HRQoL) in older adults. METHODS eighty four healthy adults aged 60 88 years were tested. A torque dynamometer was utilised to measure muscle moments at the knee and hip joints. Functional assessment involved three dimensional biomechanical analysis of gait, chair rise and sit down, stair ascent and descent using an 8 camera VICON(r) system with Kistler force plates. HRQoL was assessed using the Short Form 36 (SF 36) questionnaire. RESULTS Spearman's correlation coefficient showed significant correlation (P 0.001) between isometric strength and functional moments (r 0.24 0.67) Muscle strength was significantly correlated with SF 36 scores, including physical functioning, bodily pain, vitality, social functioning and role emotional scores. Knee flexion moment was correlated with role physical, vitality, social functioning, role emotional, mental health and mental component scores (r 0.24 0.40) CONCLUSION loss of muscle strength is associated with poorer functional ability and both are associated with reduced HRQoL. The reduction in HRQoL is considerable in the physical functioning domain. Cause and effect was not established but studies need to be undertaken to evaluate the benefits of strength training, functional activity training or increased participation in life.
Age and ageing
D Samuel Philip John Rowe V Hood A C Nicol