lens assembly
26657911
Metagenomic assembly through the lens of validation: recent advances in assessing and improving the quality of genomes assembled from metagenomes
Metagenomic samples are snapshots of complex ecosystems at work. They comprise hundreds of known and unknown species, contain multiple strain variants and vary greatly within and across environments. Many microbes found in microbial communities are not easily grown in culture making their DNA sequence our only clue into their evolutionary history and biological function. Metagenomic assembly is a computational process aimed at reconstructing genes and genomes from metagenomic mixtures. Current methods have made significant strides in reconstructing DNA segments comprising operons, tandem gene arrays and syntenic blocks. Shorter, higher throughput sequencing technologies have become the de facto standard in the field. Sequencers are now able to generate billions of short reads in only a few days. Multiple metagenomic assembly strategies, pipelines and assemblers have appeared in recent years. Owing to the inherent complexity of metagenome assembly, regardless of the assembly algorithm and sequencing method, metagenome assemblies contain errors. Recent developments in assembly validation tools have played a pivotal role in improving metagenomics assemblers. Here, we survey recent progress in the field of metagenomic assembly, provide an overview of key approaches for genomic and metagenomic assembly validation and demonstrate the insights that can be derived from assemblies through the use of assembly validation strategies. We also discuss the potential for impact of long read technologies in metagenomics. We conclude with a discussion of future challenges and opportunities in the field of metagenomic assembly and validation.
Briefings Bioinform.
Nathan D Olson Todd J Treangen Christopher Michael Hill Victoria Cepeda-Espinoza Jay Ghurye Sergey Koren Mihai Pop
125721913
Design and analysis for the flexible support structure of high precision lens assembly
In order to achieve support and positioning of lens assembly which have large aperture and high precision in the on orbit assembly space telescope validation prototype, A novel lens support structure with multi point flexible units and four point length adjustable radial holding is proposed. Then, the structure optimization is finished based on gravity deformation and thermal deformation. Finally, the influence of gravity and thermal load on the lens surface figure under this support structure is given by finite element analysis. The results show that: the largest first lens in the lens assembly is taken as an example, lens surface figure (RMS) of the upper surface causing by gravity and +2 degrees C thermal load is 3.09 nm, while the lower surface is 103 nm, and lens surface figure RMS of the upper surface causing by gravity and 2 degrees C thermal load is 3.43 nm, while the lower surface is 3.39 nm. The results and practice indicate that the multi point flexible support structure can effectively reduce the influence on lens surface figure by gravity and thermal load, and can be satisfied with the lens surface figure accuracy (RMS 4 nm)
Yan Gao Bao Zhang
26407237
Precise lens assembly techniques based on adhesive bonding and hammering for compact 100GbE TOSA
Two precise lens assembly techniques based on the adhesive bonding and hammering are proposed. These techniques allow us to realize a compact 100GbE TOSA 15.1 x 6.5 x 5.6 mm which is suitable for the QSFP28 form factor. The measured DC output powers are more than +4.0 dBm which fully achieve the target value of+1.0 dBm with the large margin.
2017 Conference on Lasers and Electro Optics Pacific Rim (CLEO PR)
Keita Mochizuki Tadashi Murao Yoshiyuki Kamo Nobuyuki Yasui Masatomo Mikuni Koji Kamiyama Takahiro Yoshimoto Daisuke Echizenya Masaya Shimono Chinatsu Sanda Hidekazu Kodera Masamichi Nogami
126022341
Design and component test results of the LSST Camera L1 L2 lens assembly
The Large Synoptic Survey Telescope (LSST) camera will be the largest camera ever constructed for astronomy. When light enters the camera it will first pass through the two large lenses of the L1 L2 Lens Assembly. This assembly consists of a 1.6 m spherical lens and a 1.2 m aspheric lens held in critical alignment by a carbon fiber composite structure. The structure is mounted to the camera structure by six adjustable struts, which provide the mechanism to align the L1 L2 Assembly to the rest of the camera optical system. Final optical performance of this assembly is based upon lens figure, lens alignment, and alignment stability. With manufacture of the individual components of the L1 L2 Lens assembly and testing of the integrated composite structure nearing completion, design, design drivers, and test results will be presented.
Optical Engineering Applications
Allison A Barto Scott E Winters James H Burge Don Davies H Doty Roger Richer P Seyforth
67349285
Precision lens assembly with alignment turning system
The poker chip assembly with high precision lens barrels is widely applied to ultra high performance optical system. ITRC applies the poker chip assembly technology to the high numerical aperture objective lenses and lithography projection lenses because of its high efficiency assembly process. In order to achieve high precision lens cell for poker chip assembly, an alignment turning system (ATS) is developed. The ATS includes measurement, alignment and turning modules. The measurement module is equipped with a non contact displacement sensor (NCDS) and an autocollimator (ACM) The NCDS and ACM are used to measure centration errors of the top and the bottom surface of a lens respectively; then the amount of adjustment of displacement and tilt with respect to the rotational axis of the turning machine for the alignment module can be determined. After measurement, alignment and turning processes on the ATS, the centration error of a lens cell with 200 mm in diameter can be controlled within 10 arcsec. Furthermore, a poker chip assembly lens cell with three sub cells is demonstrated, each sub cells are measured and accomplished with alignment and turning processes. The lens assembly test for five times by each three technicians; the average transmission centration error of assembly lens is 12.45 arcsec. The results show that ATS can achieve high assembly efficiency for precision optical systems.
Optifab
Cheng-Fang Ho Chien-Yao Huang Yi-Hao Lin Hui-Jean Kuo Ching-Hsiang Kuo Wei-Yao Hsu Fong-Zhi Chen
140257632
Lens assembly and camera module including the same
A lens assembly having a lens barrel having an internal space. The lenses are stacked in the internal space of the lens barrel. Each of the lenses has an effective portion and a rib extending in a radial direction from an outer radial edge of the effective portion; and a blocking part is provided on an axial surface of at least one rib.
126039420
Lens assembly for optical imaging
The invention relates, first aspheric positive lens element and the second aspherical negative lens element, the optical imaging lens assembly comprising in order from the object side to the image side, each of which has a target side surface and image side surface It provides a three dimensional. Elements of the optical imaging lens assembly is, (i) T <1.2f, (ii) 1.1 <f f1 <1.5, (iii) 1.5 <f f2 0.6, (iv) 0.2 <R1 f 0.5, and (v) 0.25 <K1 <may be configured so as to satisfy the relation of 0.05, f is the focal length of the lens assembly, f1 is the focal length of the first lens element, f2 is the focal length of the second lens element, R1 is the radius of curvature of the object side surface of the first lens element, K1 is the conic of the target surface of the first lens element, T is the optical lens it is the total track length.
140446786
Intraocular lens assembly
The present invention provides an intraocular lens support body for effectively transferring the movement of the zonule of Zinn, thereby improving the performance of the intraocular lens. The present invention provides an intraocular lens assembly, which is inserted into the eyeball, comprising: an intraocular lens support body (10) configured in the shape of a ring inserted into the capsular sac of the eyeball, the outer peripheral surface (11) of the intraocular lens support body (10) which contacts the capsular sac, comprising a first front contact portion (11a) that contacts the front portion of the capsular sac and a first rear contact portion (11b) that contacts the rear portion of the capsular sac, and the inner peripheral surface (12) of the intraocular lens support body (10) which faces the outer peripheral surface (11) comprising a second front contact portion (12a) that faces the first front contact portion (11a) and a second rear contact portion (12b) that faces the first rear contact portion (11b) a connection means (50) comprising a third front contact portion (52a) which contacts at least one section of the second front contact portion (12a) a third rear contact portion (52b) which contacts at least one section of the second rear contact portion (12b) and a deformation facilitating groove (52c) which is provided between the third front contact portion (52a) and the third rear contact portion (52b) so as to form a space such that the same is spaced from the inner peripheral surface (12) and an intraocular lens (30) connected to the connection means. Accordingly, the movement of the zonule of Zinn is efficiently transferred to the intraocular lens.
53389001
Developing a method for soft gamma ray Laue lens assembly and calibration
Abstract Laue lenses constitute a promising option for concentrating soft gamma rays with a large collection area and reasonable focal lengths. In astronomy they could lead to increased telescope sensitivity by one to two orders of magnitude, in particular for faint nuclear gamma ray lines, but also for continua like hard X ray tails from a variety of compact objects. Other fields like Homeland security and nuclear medicine share the same need for more sensitive gamma ray detection systems and could find applications for gamma ray focusing optics. There are two primary challenges for developing Laue lenses: the search for high reflectivity and reproducible crystals, and the development of a method to accurately orient and fix the thousands of crystals constituting a lens. In this paper we focus on the second topic. We used our dedicated X ray beamline and Laue lens assembly station to build a breadboard lens made of 15 crystals. This allowed us to test our tools and methods, as well as our simulation code and calibration procedure. Although some critical points were identified, the results are very encouraging, with a crystal orientation distribution lower than 10" as required to build a Laue lens telescope dedicated to the study of Type Ia supernovae (30 m focal length) This breadboard lens represents an important step towards raising the technology readiness level of Laue lenses.
Nicolas M Barriere John A Tomsick Steven E Boggs Alexander W Lowell Colin Wade Maxwell Baugh Peter von Ballmoos Nikolay V Abrosimov L Hanlon
141095671
Intraocular lens assembly
The invention eye as the lens structure (IOL) the front lens capsule flap is placed in the lens capsule in a state to surround the front portion of the opening of the lens capsule wherein the IOL, and the S IOL for fixing the IOL in the opening It provides an intraocular lens assembly including a secondary intraocular lens (IOL S) including a fixing portion for attachment to the IOL.
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