Sandoricum
90175470
Pengaruh Pemberian Ekstrak Etanol Daun Kecapi (Sandoricum koetjape (Burm.f. Merr. Terhadap Penurunan Kadar Kolesterol Total pada Mencit Jantan (Mus musculus)
The research about utilization of ethanol extract form leafkecapi Sandoricum koetjape (Burm.f.)Merr.)has been done, it proved could decrease total cholesterol levels in male mice Mus musculus In this research sample macerated with ethanol 96% and then concentrated by rotary evaporator, and gained 15.6% of yield. Based on the results of phytochemical test, secondary metabolites compound that contained in bark kecapi are alkaloid, flavonoid, triterpenoid, steroid, phenolic and saponin. On antihiperkolesterolemia activity test by using male mice, there are several treatments that negative control positive control and three treatment with different doses i.e. a low doses (9.5 mg/kg BB) middle doses (19 mg/kg BB) and high doses (38 mg/kg BB) The parameter measured was blood serum of male mice by using a Cholesterol Test Strips. From this test it showed that the effectiveness of decreased total cholesterol level doses of 19 mg/kg BB showed total cholesterol level under 100 mg/dL. Keywords: Leaf kecapi (Sandoricum koetjape (Burm.f. Merr. Phytochemicals test, Total cholesterol levels, Cholesterol test strips.
Rudi Kartika
90411420
Uji Aktivitas Antifungi Ekstrak dan Fraksi Daun Kecapi (Sandoricum koetja( Burm.f. Merr terhadap Candida albicans
Kecapi Sandoricum koetjape (Burm.f. Merr) merupakan salah satu tanaman obat tradisional dari suku Meliaceae, mengandung senyawa flavonoid, saponin dan polifenol yang dapat digunakan sebagai antifungi Salah satu penyakit yang disebabkan oleh Candida albicans yaitu Candidiasis. Tanaman kecapi di masyarakat, biasa digunakan untuk mengobati penyakit tersebut. Penelitian ini bertujuan untuk mengetahui aktivitas antijamur daun kecapi Sandoricum koetjape Burm.f. Merr) dalam menghambat pertumbuhan Candida albicans Uji aktivitas antifungi ekstrak etanol daun kecapi terhadap Candida albicans dilakukan dengan metode difusi agar dengan perforasi pada media Saboraud Dextrose Agar (SDA) Ekstrak etanol daun kecapi pada konsentrasi 15% memberikan aktivitas antifungi yang ditandai dengan membentuk zona hambat pada plat agar. Fraksinasi ekstrak etanol dilakukan secara Ekstraksi Cair Cair (ECC) Aktivitas antifungi tertinggi ditunjukan oleh fraksi etilasetat sebesar (23 mm) diikuti oleh fraksi N heksana sebesar (19,2 mm) ekstrak etanol sebesar (18,2 mm) dan fraksi air sebesar (13 mm) Kemudian dilakukan pemantauan komponen dalam fraksi etilasetat secara Kromatografi Lapis Tipis (KLT) menggunakan penampak bercak universal H 2 SO 4 10% dalam methanol.
Agnes Maulida Mursyid Kiki Mulkiya Yuliawati Esti Rachmawati Sadiyah
102955346
UJI AKTIVITAS ANTIOKSIDAN DARI EKSTRAK BUAH SENTUL (Sandoricum koetjape Merr.
Sentul fruit (Sandoricum koetjape Merr. is representing one kind of fruit that is amount enough abundance at West Nusa Tenggara, but it hasn't been exploited in an optimal fashion and more castaway useless. Parts of Sentul plant have been applied as traditional medicine. Sentul fruit can be oxidated by the browning reaction when it is pared or sliced, these symptoms showed the existences of phenolic compounds so that very potential as an antioxidant. To analyze the total phenolic and antioxidant activity of methanol extract of Sentul fruit, the Folin Ciocalteu and DPPH methods have been used. Results of analysis for three treatment types of samples A, B, and C) shown their total phenolic: 6,9 12,86 and 9,36 respectively and also their antioxidant activity shown by values of IC 50 of each: 43,36 ppm (1/IC50 0,023 ppm 1) 40,53 ppm (1/IC50 0,025 ppm 1) and 44,43 ppm (1/IC50 0,0225 ppm 1) respectively. These results indicated that Sentul fruit is very potential as an antioxidant.
Faizul Bayani
99377419
ISOLASI SENYAWA KUMARIN DARI KULIT BATANG KECAPI (Sandoricum koetjape) SEBAGAI ANTIBAKTERI
Isolation of coumarine on stem bark from Sandoricum koetjape has done. Stem bark powder were extracted by maceration method using organic solvents hexane, ethyl acetate and methanol. Extract of ethyl acetate was separated by column chromatography. The antibacterial activities of extracts made by method of diffusion discs. The results showed the extracts of ethyl acetate has the highest activity than others with 12 mm (Staphylococcus aureus) and 19 mm (Escherichia coli) inhibitory area. Isolation result is needle white crystals from extracts of ethyl acetate with melting point 194oC 195oC.
Febria Elvy Susanti
104462898
Uji Aktivitas Antibakteri Ekstrak Kulit Buah Kecapi (Sandoricum koetjape) terhadap Bakteri Staphylococcus aureus dan Escherichia coli
Hasil uji antibakteri ekstrak kulit buah kecapi (Sandoricum koetjape) terhadap bakteri Staphylococcus aureus dan Escherichia coli sama sama menunjukkan aktivitas antibakteri paling besar pada ekstrak etanol 75% dengan waktu inkubasi 24 jam, diameter zona hambat Staphylococcus aureus sebesar 12,02 mm dan Escherichia coli sebesar 18,12 mm. Hasil uji skrining fitokimia menunjukkan ekstrak kulit buah kecapi (Sandoricum koetjape) mengandung senyawa metabolit sekunder dari golongan flavonoid, alkaloid, terpenoid, dan tanin.
Mentari Mentari
115050930
PENGARUH KONSENTRASI BAHAN STABILISATOR PEG 1000 DAN LAMA PERENDAMAN TERHADAP KESTABILAN DIMENSI KAYU KECAPI (Sandoricum koetjape Merr)
Kayu bersifat higroskopis dan anisotropis, karena itulah untuk meningkatkan kualitas kayu diperlukan suatu perlakuan stabilisasi dimensi. Tujuan dari penelitian ini adalah untuk menguji pengaruh konsentrasi Polyethylene Glycol 1000 dan waktu perendaman terhadap stabilisasi dimensi kayu yakni nilai penyusutannya. Sampel yang digunakan dalam penelitian ini adalah Polyethylene glycol 1000, kayu Kecapi dan air suling sebagai pelarutnya. Proses stabilisasi dimensi dilakukan dengan menggunakan metode proses difusi bulking yang mengganti bahan penstabilnya dengan air. Sampel yang digunakan dalam penelitian ini adalah sebanyak 120 buah sampel. Hasil penelitian menunjukkan bahwa Polyethylene Glycol 1000 pada tingkat konsentrasi 30% dan lama perendaman 5 hari memiliki nilai stabilisasi dimensi terbaik untuk semua parameter yang diuji. Tingkat konsentrasi tertinggi untuk Polyethylene Glycol 1000 dan lama perendaman yang terlama, nilai penyusutannya paling kecil dan juga dapat meningkatkan nilai stabilisasi dimensi. Wood is h y gros c opi c and anisotropi c, hence it is needed to improve the quality of wood by dimension stabilization treatment. The aim of study is to examine the effect of Polyethylene Glycol 1000 concentration and soaking time on the shrinkage rate stabilization dimension s. Polyethylene glycol 1000 and Kecapi wood were used in the research and distilled water as a solvent. Stabilization was carried out by bulking method that replaced stabilizer material with water by diffusion process A member of 120 pieces samples were used in the study The research results showed that Polyethylene Glycol 1000 at 30% concentration level and 5 days of soaking time have the best value of stabilization for all tested parameter s. The hingher leve l concentration of Polyethylene Glycol 1000 and the longer immersion time smaller shrinkage and increa sing the value o f stabilization dimensions as well
Lusyiani Lusyiani Violet Burhanuddin Putri Nadilla
89658912
Identifikasi Kandungan Senyawa Metabolit Sekunder dan Uji Bioaktivitas Terhadap Larva Udang (Artemia salina Leach. Ekstrak Daun Kecapi (Sandoricum koetjape Merr.
Secondary metabolites identification and bioactivity of santol leaves extract (S.koetjape Merr. against Artemia salina Leach has been done. Secondary metabolite identification was done by testing santol leaves extract and fractions against reagent, whereas the bioactivity tests carried out by Brine Shrimp Lethality Test (BSLT) method. Santol leaves extract was extracted using methanol solvent and was fractioned using n hexane, ethyl acetate and n butanol solvents. The results showed that the santol leaves extract contain flavanoid, saponin, tannin, karatenoid, fenol, steroid, and triterpenoid. LC50 value of each crude extract, n hexane fraction, ethyl acetate fraction, and n butanol fraction was 190.12 ppm, 189.23 ppm, 299.23 ppm, and 301.99 ppm.
Destri Erawaty Aditya Fridayanti Laode Rijai
101274548
IDENTIFICATION OF COMPOUND ANTIFUNGI OF Sandoricum koetjape. Stem AND ACTIVITY TO Candida albicans
Kecapi (Sandoricum koetjape (Burm.f. Merr) was one of the traditional medicine from family Meliaceae and had compounds such as flavonoids, saponins and polyphenols that can be used as antifungal. The objective of this research to know compounds contained from S. koetjape bark that has potential as an antifungal toward C. albicans.Research carried out two stages using extraction by maceration with methanol and fractionation by column chromatography method used the solvent n hexane, chloroform, ethyl acetate and methanol. The next step was examined its activity toward C. albicans and identification of fraction active compounds with the Gas Chromatograpy Mass Spectrometry (GC MS) The results of this research showed that methanol extract from S. koetjape bark had antifungal activity againstC. albicans (39,654% Next, the methanol extract was fractionated and fractionation results were obtained six fractions with the greatest antifungal activity of fraction III, followed by fraction V (39.66% b/v) fraction IV (39.02% b/v) fraction II (37.91% b/v) fraction VI (35.48 b/v) and fraction I (33.72% b/v) Identification of compounds with GC MS in fraction III and compounds contained have potential as an antifungal are a gurjunene, trans caryophyllene, aromadendrene, a humulene, b caryophyllene, d Cadinene, alloaromadendrene, octadecanoic acid (as. stearat) hexadecanoic acid metil ester (metil palmitate) hexadecanoic acid (as. palmitate) 9 octadecenoic acid metil ester (metil elaidate) 9 octadecenoic acid (as. oleat)
Warsinah Warsinah Eka Kusumawati Sunarto Sunarto
89907072
Postharvest quality of waxed and wrapped Santol [Sandoricum koetjape (Burm. f. Merr. fruit
The postharvest quality of waxed and cling wrapped aBangkoka santol [Sandoricum koetjape (Burm. f. Merr. fruit held under ambient room conditions (24A+ 0.63AdegC, 86A+ 4% RH) was evaluated. At 13 DAT (days after treatment) wrapped fruit still had a good visual quality (rating of 5.4) with the least weight loss of 5.4% The lightness, L* and yellowness, b* of the skin color of santol were likewise better maintained. Consistently better visual quality and reduced decay were observed in wrapped fruit compared with the control and waxed fruit particularly at the later periods of holding where the latter fruit were fair to poor. As in control, early fruit shriveling was evident in waxed fruit while the onset was delayed in wrapped fruit. Aril pH tended to increase with time. Total soluble solids, firmness, and browning did not vary with treatment. Based on the results, the postharvest quality of aBangkoka santol fruit held at ambient is better maintained by using cling wrap film.
Emma Ruth V Bayogan A T Lacap Leizel B Secretaria V L Loquias
108542860
ISOLASI DAN KARAKTERISASI SENYAWA KUMARIN DARI EKSTRAK AKTIF ETIL ASETAT KULIT BATANG KECAPI (Sandoricum koetjape) SEBAGAI ANTIBAKTERI
Isolasi senyawa kumarin telah dilakukan dari kulit batang tumbuhan kecapi (Sandoricum koetjape) Serbuk kulit batang kecapi diekstrak dengan metoda maserasi menggunakan pelarut heksana, etil asetat dan metanol. Pemurnian ekstrak dengan kromatografi kolom dan identifikasi senyawa dilakukan dengan spektroskopi UV dan IR. Uji aktifitas antibakteri terhadap ekstrak dilakukan dengan metoda difusi cakram. Hasilnya menunjukkan aktifitas antibakteri ekstrak etil asetat lebih aktif dibandingkan ekstrak heksana dan metanol dengan daerah hambatnya 12 mm (Staphylococcus aureus) dan 19 mm (Escherichia coli) Senyawa hasil isolasi berupa kristal jarum berwarna putih yang diperoleh dari ekstrak etil asetat dengan titik leleh 194oC 195oC. Dari data spektroskopi UV dan IR menunjukkan senyawa ini merupakan senyawa kumarin yang memiliki gugus fungsi hidroksil. Kata kunci Sandoricum koetjape, kumarin, antibakteri
Elvy Susanti Febria