passionflower anxiety, sleep
54587488
A double blind, placebo controlled investigation of the effects of Passiflora incarnata (passionflower) herbal tea on subjective sleep quality. PubMed NCBI
Passiflora incarnata is a traditional herbal sedative, anxiolytic and a popular sleep aid used for the treatment of sleep disturbance. Several controlled experiments have demonstrated enhanced sleep in laboratory animals, but clinical trials in humans are lacking. The aim of the present study was to investigate the efficacy of Passiflora incarnata herbal tea on human sleep, as measured using sleep diaries validated by polysomnography (PSG) This study featured a double blind, placebo controlled, repeated measures design with a counterbalanced order of treatments (passionflower vs placebo tea) separated by a 1 week 'washout' period. Forty one participants (18 35 years) were exposed to each treatment for a week, whereby they consumed a cup of the tea and filled out a sleep diary for 7 days, and completed Spielberger's state trait anxiety inventory on the seventh morning. Ten participants also underwent overnight PSG on the last night of each treatment period. Of six sleep diary measures analysed, sleep quality showed a significantly better rating for passionflower compared with placebo (t(40) 2.70, p 0.01) These initial findings suggest that the consumption of a low dose of Passiflora incarnata, in the form of tea, yields short term subjective sleep benefits for healthy adults with mild fluctuations in sleep quality. Copyright (c) 2011 John Wiley Sons, Ltd. PMID: 21294203 [PubMed indexed for MEDLINE] PubMed Commons 0 comments Abstract 1 Author information Publication Types, MeSH Terms, Substances LinkOut more resources Full text links PubMed A double blind, placebo controlled investigation of the effe. http:/www.ncbi.nlm.nih.gov/pubmed/21294203 1 of 1 6/2/15 1:38 AM
23681993
A Double blind, Placebo controlled Investigation of the Effects of Passiflora incarnata (Passionflower) Herbal Tea on Subjective Sleep Quality
Passiflora incarnata is a traditional herbal sedative, anxiolytic and a popular sleep aid used for the treatment of sleep disturbance. Several controlled experiments have demonstrated enhanced sleep in laboratory animals, but clinical trials in humans are lacking. The aim of the present study was to investigate the efficacy of Passiflora incarnata herbal tea on human sleep, as measured using sleep diaries validated by polysomnography (PSG) This study featured a double blind, placebo controlled, repeated measures design with a counterbalanced order of treatments (passionflower vs placebo tea) separated by a 1 week 'washout' period. Forty one participants (18 35 years) were exposed to each treatment for a week, whereby they consumed a cup of the tea and filled out a sleep diary for 7 days, and completed Spielberger's state trait anxiety inventory on the seventh morning. Ten participants also underwent overnight PSG on the last night of each treatment period. Of six sleep diary measures analysed, sleep quality showed a significantly better rating for passionflower compared with placebo (t(40) 2.70, p 0.01) These initial findings suggest that the consumption of a low dose of Passiflora incarnata, in the form of tea, yields short term subjective sleep benefits for healthy adults with mild fluctuations in sleep quality. Copyright (c) 2011 John Wiley Sons, Ltd.
Phytotherapy research PTR
A Ngan Russell Conduit
71589150
Herbs for the nervous system: Ginkgo, kava, valerian, passionflower
The World Health Organization estimates that 80% of the world's population relies on herbal medicine, with the use of herbs in the United States expanding significantly in the past decade. Alternative and herbal medicines such as St. John's wort, kava, ginkgo biloba, and valerian, among others have become increasingly popular treatments for nervous and sleep disorders including stress, anxiety, dementia, and forgetfulness. This article reviews the use of ginkgo, kava, passionflower, and valerian in psychiatric practice, summarizing existing research on these major botanicals. Herbal remedies are compared with pharmaceuticals, and dosages, benefits, adverse effects, and drug herb interactions are discussed for each herb.
Hyla Cass
229685801
Passiflora incarnata in Neuropsychiatric Disorders A Systematic Review
Background: Stress is a natural response of the body, induced by factors of a physical (hunger, thirst, and infection) and/or psychological (perceived threat, anxiety, or concern) nature. Chronic, long term stress may cause problems with sleep, concentration, and memory, as well as affective disorders. The passionflower (Passiflora incarnata) is a perennial plant with documented therapeutic properties. The literature data suggest that the passionflower itself, as well as its preparations, helps reduce stress and can therefore be helpful in the treatment of insomnia, anxiety, and depression. The objective of this systematic review was to evaluate Passiflora incarnata in terms of its neuropsychiatric effects. Methods: The scientific databases PubMed, ClinTrials.gov, and Embase were searched up to 22 October 2019. The search identified randomized clinical trials describing the effects of Passiflora incarnata in neuropsychiatric disorders. Results: The systematic review included nine clinical trials. The duration of the studies included in the analysis varied widely, from one day up to 30 days. Study participants were no less than 18 years old. In each of the papers, the effects of passionflower were measured by using a number of different tests and scales. The majority of studies reported reduced anxiety levels following the administration of Passiflora incarnata preparations, with the effect less evident in people with mild anxiety symptoms. No adverse effects, including memory loss or collapse of psychometric functions, were observed. Conclusion: Passiflora incarnata may be helpful in treating some symptoms in neuropsychiatric patients.
Nutrients
Katarzyna Janda Karolina Wojtkowska Karolina Jakubczyk Justyna Antoniewicz Karolina Skonieczna-Zydecka
10353305
Anxiety, depression, and insomnia.
Evidence for alternative treatments for depression, anxiety, and insomnia are reviewed in this article. Treatment of depression with St. John's wort, L tryptophan, 5 hydroxytryptophan, S adenosylmethionine, dehydroepiandosterone, folate, exercise, acupuncture, and meditation are examined. Evidence for the efficacy of kava kava, exercise, relaxation therapies, and acupuncture in treatment anxiety is reviewed. The use of valerian, melatonin, chamomile, passionflower, exercise, acupuncture, and behavioral therapies (i.e. sleep restriction, stimulus control, relaxation, and sleep hygiene) for insomnia is discussed.
Primary care
Michele McCarthy Larzelere Pamela M Wiseman
39275610
Complementary and alternative medicine usage for behavioral health indications.
Evidence on the use of complementary and alternative medicine (CAM) modalities in the treatment of depression, anxiety, sleep disorders, and attention deficit/hyperactivity disorder (ADHD) is reviewed. There is strong evidence to support the use of St. John's wort (SJW) in depression, and growing support for the use of omega 3 fatty acids and S adenosyl l methionine as potential adjuncts to conventional therapies. Evidence is insufficient to support the antidepressant benefit of dehydroepiandrosterone, inositol, folate, and saffron. Only kava has high quality evidence for use in the treatment of anxiety disorders, and its use is discouraged because of safety concerns. There is preliminary supportive evidence for valerian and inositol treatment of anxiety, but SJW and passionflower have achieved little research support. Melatonin is likely to be useful in treating delayed sleep phase, jet lag, or shift work, but there is little evidence for the benefit of valerian compared with placebo. There are currently no evidence supported CAM treatments for ADHD (zinc and omega 3 fatty acids are reviewed)
Primary care
Michele McCarthy Larzelere James S Campbell Marta Robertson
54930481
Herbal Medicines In The Treatment of Psychiatric and Neurological Disorders
Objective: This review will indicate the quality of the evidence supporting the clinical effects of a number of commonly used types of herbal medicines for psychiatric and neurological disorders. Method: We conducted a review of literature to understand the biochemical and evidential bases for the use of herbs in psychiatric and neurological disorders as follow: 1) Alzheimer's disease, 2) Depression, 3) Anxiety, 4) Insomnia, 5) Substance use disorders, 6) Attention deficit/hyperactivity disorder (ADHD) 7) Migraine. Results: Evidences support use of Ginkgo biloba, Huperzine A, Galantamine, Melissa officinalis,and Salvia officinalis for Alzheimer's disease; St. John's wort, Lavender, and Saffron for depression; Passionflower, and Kava, for anxiety disorders; Valerian, and English Lavender for sleep disorders; Hypericum for substance related disorders; Ginkgo biloba, and Passionflower for ADHD; and feverfew, and Butterbur root for migraine. The highest level of confidence derives from well designed, randomized, double blind controlled studies. Conclusion: Herbs may have beneficial effects in variety of psychiatric and neurological disorder; however we must consider their potential side effects and drug drug interactions.
Shahin Akhondzadeh Javad Maleki
68600162
Concise Handbook of Psychoactive Herbs: Medicinal Herbs for Treating Psychological and Neurological Problems
Chapter 1. Introduction Plants As Medicines The Use of Herbal Medicines Why Do Plants Make Drugs? How Humans Came to Use Herbal Medicines The Science of Herbal Medicines Summary Chapter 2. How the Brain Works Mind, Brain, and Behavior Communication in and Between Neurons Structure of the Nervous System Chapter 3. How Drugs Work How the Body Affects Drugs How Drugs Affect the Body Relationships Between Drug Doses and Effects Chapter 4. Stimulant Herbs Pharmaceutical Stimulants Caffeine Stimulants Tobacco and Tobacco Like Stimulants Amphetamine Like Stimulants Summary Chapter 5. Cognition Enhancing Herbs Discussion and Treatment of Dementia Ginkgo Ginseng Tobacco Solanaceous Vegetables: Tomato, Potato, and Eggplant Discussion and Treatment of Parkinson's Disease Fava Beans Summary Chapter 6. Sedative and Anti Anxiety Herbs The Problem of Anxiety Insomnia The Structure of Sleep Central Nervous System Depressants Valerian Kava Passionflower Chamomile Other Reputed Sedative Herbs Summary Chapter 7. Herbs for Mental Illnesses The Era of Psychotherapeutic Drugs Depression and Anxiety St. John's Wort Ginger Ginkgo Schizophrenia and Psychosis Chapter 8. Herbal Painkillers What Is Pain? The Pain Systems The Analgesia System Herbal Analgesics Opium Poppy Myrrh Willow Meadowsweet Feverfew Ginger Chili Peppers Stimulant Analgesics Local Anesthetic Herbs Chapter 9. Herbal Hallucinogens What to Call Them? The Historical Uses of Hallucinogenic Plants LSD Like Hallucinogens Collective Issues with LSD Like Hallucinogens The Nightshade Hallucinogens Fly Agaric Chapter 10. Cannabis History Cannabis and the Human Body Cannabis Addiction Therapeutic Uses of Cannabis Summary Chapter 11. Use, Abuse, and Addiction Definitions Evolutionary Basis for Drug Abuse Psychological Perspective Addiction in the Brain Are Addictions Limited to Drugs? Treatment Treatment Methods Prevention Conclusions Glossary Bibliography Index Reference Notes Included
Marcello Spinella
218473020
COVID 19, anxiety, sleep disturbances and suicide
Sleep Medicine
Leo Sher
218582834
The enemy who sealed the world: effects quarantine due to the COVID 19 on sleep quality, anxiety, and psychological distress in the Italian population
Abstract Background The 2019 Coronavirus Disease (COVID 19) pandemic has become a global health emergency. The extreme actions aimed to reduce virus diffusion have profoundly changed the lifestyles of the Italian population. Moreover, fear of contracting the infection has generated high levels of anxiety. This study aimed to understand the psychological impact of the COVID 19 outbreak on sleep quality, general anxiety symptomatology, and psychological distress. Methods An online survey collected information on socio demographic data and additional information concerning the COVID 19 pandemic. Furthermore, sleep quality, sleep disorders, generalized anxiety symptoms, psychological distress, and post traumatic stress disorder (PTSD) symptomatology related to COVID 19 were assessed. Results This study included 2291 respondents. The results revealed that 57.1% of participants reported poor sleep quality, 32.1% high anxiety, 41.8% high distress, and 7.6% reported PTSD symptomatology linked to COVID 19. Youth and women, those uncertain regarding possible COVID 19 infection, and greater fear of direct contact with those infected by COVID 19 had an increased risk of developing sleep disturbances, as well as higher levels of anxiety and distress. Finally, a significant relationship between sleep quality, generalized anxiety, and psychological distress with PTSD symptoms related to COVID 19 was evidenced. Conclusions Our findings indicate that the COVID 19 pandemic appears to be a risk factor for sleep disorders and psychological diseases in the Italian population, as previously reported in China. These results should be used as a starting point for further studies aimed to develop psychological interventions to minimize the brief and long term consequences of the COVID 19 pandemic.
Sleep Medicine
Maria Casagrande Francesca Favieri Renata Tambelli Giuseppe Forte