6801442
Fast protein classification with multiple networks
MOTIVATION
Support vector machines (SVMs) have been successfully used to classify proteins into functional categories. Recently, to integrate multiple data sources, a semidefinite programming (SDP) based SVM method was introduced. In SDP/SVM, multiple kernel matrices corresponding to each of data sources are combined with weights obtained by solving an SDP. However, when trying to apply SDP/SVM to large problems, the computational cost can become prohibitive, since both converting the data to a kernel matrix for the SVM and solving the SDP are time and memory demanding. Another application-specific drawback arises when some of the data sources are protein networks. A common method of converting the network to a kernel matrix is the diffusion kernel method, which has time complexity of O(n(3)), and produces a dense matrix of size n x n.


RESULTS
We propose an efficient method of protein classification using multiple protein networks. Available protein networks, such as a physical interaction network or a metabolic network, can be directly incorporated. Vectorial data can also be incorporated after conversion into a network by means of neighbor point connection. Similar to the SDP/SVM method, the combination weights are obtained by convex optimization. Due to the sparsity of network edges, the computation time is nearly linear in the number of edges of the combined network. Additionally, the combination weights provide information useful for discarding noisy or irrelevant networks. Experiments on function prediction of 3588 yeast proteins show promising results: the computation time is enormously reduced, while the accuracy is still comparable to the SDP/SVM method.


AVAILABILITY
Software and data will be available on request.
15456079
Neighborhood PropertyBased Pattern Selection for Support Vector Machines
The support vector machine (SVM) has been spotlighted in the machine learning community because of its theoretical soundness and practical performance. When applied to a large data set, however, it requires a large memory and a long time for training. To cope with the practical difficulty, we propose a pattern selection algorithm based on neighborhood properties. The idea is to select only the patterns that are likely to be located near the decision boundary. Those patterns are expected to be more informative than the randomly selected patterns. The experimental results provide promising evidence that it is possible to successfully employ the proposed algorithm ahead of SVM training.
18209378
Graph Based Semi-supervised Learning with Sharper Edges
In many graph-based semi-supervised learning algorithms, edge weights are assumed to be fixed and determined by the data points' (often symmetric) relationships in input space, without considering directionality. However, relationships may be more informative in one direction (e.g. from labelled to unlabelled) than in the reverse direction, and some relationships (e.g. strong weights between oppositely labelled points) are unhelpful in either direction. Undesirable edges may reduce the amount of influence an informative point can propagate to its neighbours - the point and its outgoing edges have been blunted. We present an approach to sharpening in which weights are adjusted to meet an optimization criterion wherever they are directed towards labelled points. This principle can be applied to a wide variety of algorithms. In the current paper, we present one ad hoc solution satisfying the principle, in order to show that. it can improve performance on a number of publicly available benchmark data sets.
1668855
Fast Pattern Selection Algorithm for Support Vector Classifiers: Time Complexity Analysis
Training SVM requires large memory and long cpu time when the pattern set is large. To alleviate the computational burden in SVM training, we propose a fast preprocessing algorithm which selects only the patterns near the decision boundary. The time complexity of the proposed algorithm is much smaller than that of the naive M 2 algorithm
17704623
Invariance of neighborhood relation under input space to feature space mapping
If the training pattern set is large, it takes a large memory and a long time to train support vector machine (SVM). Recently, we proposed neighborhood property based pattern selection algorithm (NPPS) which selects only the patterns that are likely to be near the decision boundary ahead of SVM training Proc. of the 7th Pacific-Asia Conference on Knowledge Discovery and Data Mining (PAKDD), Lecture Notes in Artificial Intelligence (LNAI 2637), Seoul, Korea, pp. 376-387. NPPS tries to identify those patterns that are likely to become support vectors in feature space. Preliminary reports show its effectiveness: SVM training time was reduced by two orders of magnitude with almost no loss in accuracy for various datasets. It has to be noted, however, that decision boundary of SVM and support vectors are all defined in feature space while NPPS described above operates in input space. If neighborhood relation in input space is not preserved in feature space, NPPS may not always be effective. In this paper, we show that the neighborhood relation is invariant under input to feature space mapping. The result assures that the patterns selected by NPPS in input space are likely to be located near decision boundary in feature space.
9432088
Response modeling with support vector machines
Support Vector Machine (SVM) employs Structural Risk Minimization (SRM) principle to generalize better than conventional machine learning methods employing the traditional Empirical Risk Minimization (ERM) principle. When applying SVM to response modeling in direct marketing, however, one has to deal with the practical difficulties: large training data, class imbalance and scoring from binary SVM output. For the first difficulty, we propose a way to alleviate or solve it through a novel informative sampling. For the latter two difficulties, we provide guidelines within SVM framework so that one can readily use the paper as a quick reference for SVM response modeling: use of different costs for different classes and use of distance to decision boundary, respectively. This paper also provides various evaluation measures for response models in terms of accuracies, lift chart analysis, and computational efficiency.
34064197
The study of quick download mechanism in an infrastructural wireless environment
Frequent handoff consumes a lot of system capability and signalling resources in a mobile system. In this paper, we present download mechanisms in mobile systems or broadcast systems to support data users to receive the whole packet in time before moving out of the coverage area. Three download strategies: Quick Download using Multi-channel (QDM) scheme, Prior Download using Single channel (PDS) scheme and the Quit Download (QUD) scheme are proposed in this study where the efficiencies of the three strategies are compared with the one without particular treatment. Some significant estimations such as the percentage of handoff data users having completed service before leaving the cell, the mean waiting time of non-handoff data users, and the blocking probability of data users are analysed and compared. The numerical results show that, the QDM strategy is most efficient in reducing the handoff rate, the QUD strategy can assure the waiting time of non-handoff data users and the PDS strategy can keep the handoff rate constant at light and heavy voice load. Furthermore, various number of guard channels for data users are evaluated in terms of data and voice performance based on various download strategies. Copyright © 2006 John Wiley & Sons, Ltd.
2296282
On the error probability of binary and M-ary signals in Nakagami-m fading channels
In this letter, we present new closed-form formulas for the exact average symbol-error rate (SER) of binary and M-ary signals over Nakagami-m fading channels with arbitrary fading index m. Using the well-known moment generating function-based analysis approach, we express the average SER in terms of the higher transcendental functions such as the Gauss hypergeometric function, Appell hypergeometric function, or Lauricella function. The results are generally applicable to arbitrary real-valued m. Furthermore, with the aid of reduction formulas of hypergeometric functions, we show previously published results for Rayleigh fading (m=1) as special cases of our expressions.
5638609
Color image segmentation
In this work, a new approach to fully automatic color image segmentation, called JSEG, is presented. First, colors in the image are quantized to several representing classes that can be used to differentiate regions in the image. Then, image pixel colors are replaced by their corresponding color class labels, thus forming a class-map of the image. A criterion for "good" segmentation using this class-map is proposed. Applying the criterion to local windows in the class-map results in the "J-image", in which high and low values correspond to possible region boundaries and region centers, respectively. A region growing method is then used to segment the image based on the multi-scale J-images. Experiments show that JSEG provides good segmentation results on a variety of images.
6919897
An Accurate Worst Case Timing Analysis for RISC Processors
An accurate and safe estimation of a task's worst case execution time (WCET) is crucial for reasoning about the timing properties of real-time systems. In RISC processors, the execution time of a program construct (e.g., a statement) is affected by various factors such as cache hits/misses and pipeline hazards, and these factors impose serious problems in analyzing the WCETs of tasks. To analyze the timing effects of RISC's pipelined execution and cache memory, we propose extensions to the original timing schema where the timing information associated with each program construct is a simple time-bound. In our approach, associated with each program construct is worst case timing abstraction, (WCTA), which contains detailed timing information of every execution path that might be the worst case execution path of the program construct. This extension leads to a revised timing schema that is similar to the original timing schema except that concatenation and pruning operations on WCTAs are newly defined to replace the add and max operations on time-bounds in the original timing schema. Our revised timing schema accurately accounts for the timing effects of pipelined execution and cache memory not only within but also across program constructs. This paper also reports on preliminary results of WCET analysis for a RISC processor. Our results show that tight WCET bounds (within a maximum of about 30% overestimation) can be obtained by using the revised timing schema approach.
34315220
The study of dynamic multi-channel scheme with channel de-allocation in wireless networks
This paper proposes an analytical model to demonstrate the benefit of data service in wireless networks using dynamic multi-channel scheme with channel de-allocation (DMC-w-DA). Buffers are provided for voice calls to reduce the voice blocking probability caused by data packets contention. All free channels are allocated to data users dynamically. For those data users using more than one channel, channels would be de-allocated for new requests, voice or data. Handoff calls are given priority to be queued in the front of the buffer instead of providing guard channels to reduce their dropping probability To compensate the data packet loss probability in data, guard channels are provided for data traffic. Based on a given handoff dwell time, we analyze the dropping probability of handoff call. The probability distribution of receiving service within the handoff dwell time is obtained for each buffered handoff call and based on this result, an appropriate amount of handoff call allowed in buffer is obtained. Numerical results show that the dynamic multi-channel scheme with possible de-allocation, compared with the dynamic channel scheme without channel de-allocation, fixed channel allocation and single channel allocation scheme, can enhance data traffic performance significantly in terms of the mean service time and the packet loss probability. A system providing buffer to voice traffic and giving priority to queued handoff calls can indeed decrease new call blocking probability and handoff call dropping probability.