Electrochemical investigation of nucleic acid behaviour: Part II. a.c. polarographic investigations of methylated DNA
Abstract The a.c. polarogram obtained in the case of chemically methylated Micrococcus lysodeikticus DNA is characterized by the appearance of a supplementary peak. Within the range of pH, studied this peak corresponds to a reduction in the adsorbed state without desorption of the reduced products. This peak is characteristic of the structural modifications of the DNA by methylation at the level of the guanine-cytosine base pairing.