ff ects of low-dose nifedipine on urinary protein excretion rate in patients with renal disease
Conclusions. (1) Nifedipine 10 mg orally did not impair tubular protein reabsorption. (2) Nifedipine Background. The observation that proteinuria is an important determinant of the progression of renal had no immediate antiproteinuric effect despite the observed blood pressure reduction. (3) Nifedipine disease has prompted numerous studies on the effects of antihypertensive agents on protein excretion. increased proteinuria in ambulatory urine collections. This latter observation might explain the seemingly Reports on the proteinuric effects of calcium-channel blockers are quite controversial. It has been suggested different effects of dihydropyridine calcium-channel blockers as reported in previous studies. that the short-acting dihydropyridine calcium-channel blocker nifedipine increases protein excretion by inter