Long-term effects of fenofibrate on VLDL and HDL subspecies in participants with type 2 diabetes mellitus
An incorrect conversion factor was used by the authors resulting in values given in g/l being ten times higher than they should have been. The corrected sections of Tables 1, 2, 3, 4 are reproduced below. In addition there are two text corrections: The last paragraph of the Abstract should have read: Conclusions/interpretation Fenofibrate markedly reduced large VLDL particles and produced a clear shift in HDL subspecies towards smaller particles. The HDL3-C increase in conjunction with unchanged apoA-I levels is a dilemma with regard to cardiovascular disease. The last sentence of the subsection on ‘Impact of homocysteine levels on HDL’ in the Results should have read: In patients with low homocysteine levels (n=42), HDL-C and apoA-I levels were slightly increased by fenofibrate (Δ=0.05 mmol/l for HDL-C and Δ=0.034 g/l for apoA-I), whereas in patients with high homocysteine levels (n=42) HDL-C and apoA-I levels decreased (Δ=−0.04 mmol/l for HDL-C and Δ=−0.014 g/l for apoA-I) (p=0.028 for both the differences in ΔHDL-C and ΔapoA-I between the low and high homocysteine groups). Diabetologia (2007) 50:2611–2613 DOI 10.1007/s00125-007-0845-3